BDBM50376106 CHEMBL259638

SMILES O=C1Cc2c([nH]c3ccc(cc23)C#N)-c2ncccc2N1

InChI Key InChIKey=MGQSIUXWCFOENX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50376106   

TargetCyclin-dependent kinase 5 activator 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376106BDBM50376106(CHEMBL259638)
Affinity DataIC50: 300nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376106BDBM50376106(CHEMBL259638)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376106BDBM50376106(CHEMBL259638)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376106BDBM50376106(CHEMBL259638)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed