BDBM50314505 CHEMBL1089026::N-isopropyl-N-(6-methoxypyridin-3-yl)-5-o-tolylpyrazine-2-carboxamide

SMILES C#CCN(C)Cc1ccc(N(CC)C(=O)c2cc(C(C)C)c(O)cc2O)cc1

InChI Key InChIKey=ORHJUUZFBBHDBO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314505   

TargetHeat shock protein HSP 90-alpha(Human)
Taipei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314505BDBM50314505(CHEMBL6092104)
Affinity DataIC50: 0.540nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetLysine-specific histone demethylase 1A(Human)
Taipei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314505BDBM50314505(CHEMBL6092104)
Affinity DataIC50: 7.18E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed