BDBM50295775 2-(4-(6-methoxypyridin-3-yl)-5-methyl-4H-1,2,4-triazol-3-yl)-5-(2-(methylthio)phenoxy)pyrazine::CHEMBL561520

SMILES Cc1[nH]c(C(=O)Nc2ccc(-c3nnn[nH]3)cc2N2CCCC(CN)C2)c(Cl)c1Cl

InChI Key InChIKey=FENMUNUGOFAACO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295775   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295775BDBM50295775(CHEMBL6074536)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of BACE1 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295775BDBM50295775(CHEMBL6074536)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed