BDBM50274547 CHEMBL484547::diethyl 2-(4-(benzyloxy)benzylidene)malonate

SMILES Cc1[nH]c(C(=O)Nc2ccc(-c3noc(=O)[nH]3)cc2N2CCC(N)CC2)c(Cl)c1Cl

InChI Key InChIKey=LZZXQJZRMAWSJH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274547   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274547BDBM50274547(CHEMBL6092076)
Affinity DataIC50: 0.253nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274547BDBM50274547(CHEMBL6092076)
Affinity DataIC50: 2.62E+4nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed