BDBM50274435 4-[1-[3-(3-Methyl-benzyloxy)-phenyl]-methylidene]-1-(pyridine-4-carbonyl)-pyrazolidine-3,5-dione::CHEMBL520976

SMILES Cc1[nH]c(C(=O)Nc2ccc(-c3noc(=O)[nH]3)cc2N2CCN(C(=O)OC(C)(C)C)CC2)c(Cl)c1Cl

InChI Key InChIKey=MRRVJYUMKYXNHN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274435   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274435BDBM50274435(CHEMBL6077983)
Affinity DataIC50: 14nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed