BDBM50229216 CHEMBL254742::N-(4-(2-hydroxy-3,4-dioxocyclobut-1-enyl)benzyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxamide

SMILES O=C(N[C@H](COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)Cc1ccccc1)c1ccccc1

InChI Key InChIKey=XICWOOPHRLYMIR-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229216   

TargetProcathepsin L(Human)
Seoul National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229216BDBM50229216(ASPERPHENAMATE)
Affinity DataIC50: 9.12E+4nMAssay Description:Antagonist activity at human PPAR-alpha assessed as inhibition of GW7647-induced effect after overnight incubation by cell-based luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed