BDBM50161825 3-((Z)-2-Carboxy-2-phenyl-vinyl)-4,6-dichloro-1H-indole-2-carboxylic acid (cis)::CHEMBL179574::cid_5353745

SMILES Cc1ccc(-n2nnnc2CNC(=O)NCc2nnnn2-c2ccc(C)c(C)c2)cc1C

InChI Key InChIKey=LPWVUDLZUVBQGP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161825   

TargetPyruvate kinase PKLR(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161825BDBM50161825(CHEMBL6078153)
Affinity DataEC50:  290nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed