BDBM50139609 3-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)-N-methylbenzamide::3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-phenoxy}-N-methyl-benzamide::CHEMBL166030

SMILES CNC(=O)c1cccc(Oc2ccc(NC(=O)Nc3cc(on3)C(C)(C)C)cc2)c1

InChI Key InChIKey=NACKJUZBJUGMSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139609   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139609BDBM50139609(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139609BDBM50139609(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Raf-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139609BDBM50139609(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 1.20E+5nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed