BDBM50108236 (S)-3-[4-(4-Acetyl-piperazine-1-carbonyl)-phenyl]-2-[((S)-1-benzyl-5-oxo-pyrrolidine-2-carbonyl)-amino]-propionic acid::CHEMBL32060

SMILES Cc1ccc(-n2nnnc2CNC(=O)Nc2cccs2)cc1C

InChI Key InChIKey=FXNUCHXDIULYQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108236   

TargetPyruvate kinase PKLR(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108236BDBM50108236(CHEMBL6103083)
Affinity DataEC50:  3.50E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetPyruvate kinase PKLR(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108236BDBM50108236(CHEMBL6103083)
Affinity DataEC50:  4.60E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed