BDBM50108235 (S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)-amino]-3-[4-((S)-1-phenyl-ethylcarbamoyl)-phenyl]-propionic acid::CHEMBL29005

SMILES Cc1nc(CNC(=O)NCc2ncnn2-c2ccc3cccnc3c2)n(-c2ccc(Cl)c(F)c2)n1

InChI Key InChIKey=WXQLXHGOKLKOED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108235   

TargetPyruvate kinase PKLR(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108235BDBM50108235(CHEMBL6133200)
Affinity DataEC50:  28nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetPyruvate kinase PKLR(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108235BDBM50108235(CHEMBL6133200)
Affinity DataEC50:  375nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed