BDBM50086228 CHEMBL3425726

SMILES Oc1cn(ccc1=O)-c1ccccc1

InChI Key InChIKey=LOTDBSFZJRXRMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50086228   

TargetCatechol O-methyltransferase(Rat)
University of Porto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086228BDBM50086228(CHEMBL3425726)
Affinity DataIC50: 101nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetCatechol O-methyltransferase(Rat)
University of Porto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086228BDBM50086228(CHEMBL3425726)
Affinity DataIC50: 380nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetCatechol O-methyltransferase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086228BDBM50086228(CHEMBL3425726)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
University of Porto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086228BDBM50086228(CHEMBL3425726)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed