BDBM50065454 CHEBI:63453::CHEMBL3348846

SMILES COc1cc(CCc2cc(NC(=O)c3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)n[nH]2)cc(OC)c1

InChI Key InChIKey=VRQMAABPASPXMW-UHFFFAOYSA-N

Data  79 IC50  3 Kd  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 94 hits for monomerid = 50065454   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human FGFR1 in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human FGFR1 in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human FGFR1 in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FGFR1 in human KG1 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to FGFR1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FGFR2 using poly (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FGFR2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FGFR2 using poly (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FGFR3 in human RT112 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human FGFR1 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of FGFR1 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA based spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of FGFR1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR1 (399 to 822 residues) expressed in baculovirus infected Sf9 cells incubated for 60 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of FGFR1 (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of FGFR1 (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FGFR1 (459 to 765 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human FGFR3 in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human FGFR3 in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human FGFR3 in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FGFR3 (450 to 758 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to FGFR3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human FGFR2 (458 to 768 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human FGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human FGFR2 in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human FGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human FGFR2 in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human FGFR2 in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to FGFR2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065454BDBM50065454(CHEMBL3348846 | CHEBI:63453)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
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