BDBM485849 US10946019, Example 4

SMILES OC(=O)c1ccc(Nc2nc(nc(c2CC=C)C(F)(F)F)-c2ccccc2)cc1

InChI Key InChIKey=ZAFMYTXBZLETPN-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 485849   

TargetNuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha(Human)
University of Ioannina

Curated by ChEMBL

LigandBDBM485849(US10946019, Example 4)Copy SMILESCopy InChI

Affinity DataEC50:  200nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
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TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent

LigandBDBM485849(US10946019, Example 4)Copy SMILESCopy InChI

Affinity DataEC50:  200nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/26/2021
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL