BDBM485848 US10946019, Example 3

SMILES CN(c1ccc(cc1)C(O)=O)c1nc(nc(c1CC=C)C(F)(F)F)-c1ccccc1

InChI Key InChIKey=WFLMIJKKTIOYSO-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 485848   

TargetNuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha(Human)
University of Ioannina

Curated by ChEMBL

LigandBDBM485848(US10946019, Example 3)Copy SMILESCopy InChI

Affinity DataEC50:  900nMAssay Description:Activation of Nurr1-RXRalpha (unknown origin) heterodimer transfected in HEK293 cells co-transfected with pcDNA3 incubated for 16 hrs by Dual-Glo luc...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent

LigandBDBM485848(US10946019, Example 3)Copy SMILESCopy InChI

Affinity DataEC50:  900nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/26/2021
Entry Details
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