BDBM308372 US9649309, Compound UNC1817A

SMILES CCCCNc1ncc(C(=O)NCc2ccc(cc2)S(N)(=O)=O)c(NC2CC[C@H](O)CC2)n1

InChI Key InChIKey=CQFHCAGCNILQLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 308372   

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308372BDBM308372(US9649309, Compound UNC1817A)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MER (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as fluorogenic substrate incubated for 60 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308372BDBM308372(US9649309, Compound UNC1817A)
Affinity DataIC50: 10nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308372BDBM308372(US9649309, Compound UNC1817A)
Affinity DataIC50: 72nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as fluorogenic substrate incubated for 60 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed