BDBM229718 US9334269, 45

SMILES CC[C@@H]1CN([C@@H]2CC[C@H](c3nc(-c4cnc(C(F)(F)F)c(F)c4)nn3C(C)C)C2)CCO1

InChI Key InChIKey=GWZPJOODPNBCRI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229718   

Target7-dehydrocholesterol reductase(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 229718BDBM229718((R)-2-ethyl-4-((1R,3S)-3-(3- (5-fluoro-6-(trifluor...)
Affinity DataKi:  11.3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent