BDBM226310 US9328096, 3

SMILES C[C@H]9Cc1c([nH]c2ccccc12)[C@H](c8cnc(N3CCC7(CC3)C[C@@H](CN6CCC(c5ccc(N[C@@H]4CCC(=O)NC4=O)cc5)CC6)CO7)nc8)N9CC(F)F

InChI Key InChIKey=CFHYOADDEKEKQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226310   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 226310BDBM226310((R)-3-((4-(1-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroe...)
Affinity DataIC50: 275nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent