BDBM20157 1-benzyl-3-phenyl-4-(phenylamino)-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 5

SMILES O=C1N(Cc2ccccc2)C(=O)C(=C1Nc1ccccc1)c1ccccc1

InChI Key InChIKey=GLDDBILAEOMQJI-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 20157   

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 20157BDBM20157(GSK3987 Analogue | 1-benzyl-3-phenyl-4-(phenylamin...)
Affinity DataEC50:  70nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 20157BDBM20157(GSK3987 Analogue | 1-benzyl-3-phenyl-4-(phenylamin...)
Affinity DataEC50:  100nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 20157BDBM20157(GSK3987 Analogue | 1-benzyl-3-phenyl-4-(phenylamin...)
Affinity DataEC50:  265nMAssay Description:Agonist activity at GST-tagged LXRbeta LBD (unknown origin) measured after 6 hrs in presence of fluorescein-TRAP220/DRIP-2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 20157BDBM20157(GSK3987 Analogue | 1-benzyl-3-phenyl-4-(phenylamin...)
Affinity DataEC50:  312nMAssay Description:Agonist activity at GST-tagged LXRalpha LBD (unknown origin) measured after 6 hrs in presence of fluorescein-TRAP220/DRIP-2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed