BDBM187491 US9169252, 91

SMILES CC(C)Nc1cc(ncc1C(=O)N[C@H]1CC[C@@H](CC1)C(=O)NC1CC1)-n1ccc2cc(cnc12)C#N

InChI Key InChIKey=QPYNPSIRCQLZNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 187491   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 187491BDBM187491(US9169252, 91)
Affinity DataIC50: 2nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 187491BDBM187491(US9169252, 91)
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed