BDBM114367 2-[(2-tert-butyl-4-quinazolinyl)thio]acetic acid ethyl ester::2-[(2-tert-butylquinazolin-4-yl)thio]acetic acid ethyl ester::MLS000709831::SMR000286998::cid_1442473::ethyl 2-(2-tert-butylquinazolin-4-yl)sulfanylacetate::ethyl 2-(2-tert-butylquinazolin-4-yl)sulfanylethanoate

SMILES Cc1cc2n(Cc3ccc(S(N)(=O)=O)nc3)cc(C(C)C)c(=O)n2n1

InChI Key InChIKey=KBCUNRKOHQPPAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 114367   

LigandChemical structure of BindingDB Monomer ID 114367BDBM114367(US20260001886, Compound 16)
Affinity DataKd:  1.58nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 114367BDBM114367(US20260001886, Compound 16)
Affinity DataEC50:  2.51nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
RE Ventures I

US Patent
LigandChemical structure of BindingDB Monomer ID 114367BDBM114367(US20260001886, Compound 16)
Affinity DataKd:  1.00E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetCarbonic anhydrase 1(Human)
RE Ventures I

US Patent
LigandChemical structure of BindingDB Monomer ID 114367BDBM114367(US20260001886, Compound 16)
Affinity DataKd:  3.98E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent