BDBM106940 US8592468, EbSe7

SMILES Clc1ccc(cc1)-n1[se]c2ccccc2c1=O

InChI Key InChIKey=KIFWXWMOJVGFLN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106940   

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandChemical structure of BindingDB Monomer ID 106940BDBM106940(US8592468, EbSe7)
Affinity DataKi:  550nM IC50: 7.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shandong Second Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 106940BDBM106940(US8592468, EbSe7)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease preincubated for 75 mins followed by urea addition and measured after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed