34 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Medicinal chemistry-based perspectives on thiophene and its derivatives: exploring structural insights to discover plausible druggable leads.
Birla Institute of Technology and Sciences Pilani Pilani Campus
Design and synthesis of N-(3-cyanothiophen-2-yl)-2-phenoxyacetamide-based α-glucosidase inhibitors.
University of Jinan
1-Deoxynojirimycin Derivative Containing Tegafur Induced HCT-116 Cell Apoptosis through Mitochondrial Dysfunction and Oxidative Stress Pathway.
Jiangsu University of Science and Technology
Hydrazinecarboxamides: Comprehensive review of their anticancer, anticonvulsive, anti-inflammatory, enzyme inhibition, antioxidant and other activities.
Charles University
Designed and synthesized novel tripeptides targeting diabetes and its related pathologies.
Ha'il University
Design, synthesis and enzymatic inhibition evaluation of novel 4-hydroxy Pd-C-Ⅲ derivatives as α-glucosidase and PTP1B dual-target inhibitors.
The Affiliated Hospital of Guizhou Medical University
Synthesis, highly potent α-glucosidase inhibition, antioxidant and molecular docking of various novel dihydropyrimidine derivatives to treat diabetes mellitus.
NED University of Engineering and Technology
Advancing drug discovery: Thiadiazole derivatives as multifaceted agents in medicinal chemistry and pharmacology.
Purdue University
Quinoline-based Schiff bases as possible antidiabetic agents: ligand-based pharmacophore modeling, 3D QSAR, docking, and molecular dynamics simulations study.
KLE College of Pharmacy
Thiazolidine-2,4-dione hybrids as dual alpha-amylase and alpha-glucosidase inhibitors: design, synthesis, in vitro and in vivo anti-diabetic evaluation.
IK Gujral Punjab Technical University
Review of bioactivity and structure-activity relationship on baicalein (5,6,7-trihydroxyflavone) and wogonin (5,7-dihydroxy-8-methoxyflavone) derivatives: Structural modifications inspired from flavonoids in Scutellaria baicalensis.
Shaanxi University of Chinese Medicine
Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species.
Tanta University
Synthesis of benzotriazoles derivatives and their dual potential as α-amylase and α-glucosidase inhibitors in vitro: Structure-activity relationship, molecular docking, and kinetic studies.
University of Karachi
Role of sulphur-heterocycles in medicinal chemistry: An update.
Maharaja Ranjit Singh Punjab Technical University
Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion.
Sun Yat-Sen University
α-Glucosidase inhibition activity and in silico study of 2-(benzo[d][1,3]dioxol-5-yl)-4H-chromen-4-one, a synthetic derivative of flavone.
Goa University
1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview.
Chinese Academy of Sciences
Rational approaches, design strategies, structure activity relationship and mechanistic insights for therapeutic coumarin hybrids.
Guru Nanak Dev University
Natural dimers of coumarin, chalcones, and resveratrol and the link between structure and pharmacology.
Nagasaki International University
Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review.
Wuhan University of Technology
Synthesis, in vitro and in vivo evaluation of 2-aryl-4H-chromene and 3-aryl-1H-benzo[f]chromene derivatives as novel α-glucosidase inhibitors.
Volgograd State Medical University
Synthetic heterocyclic candidates as promising α-glucosidase inhibitors: An overview.
Babasaheb Bhimrao Ambedkar University (A Central University)
Recent advances in the chemistry and biology of oleanolic acid and its derivatives.
Merck-Life Science
4-epi-Isofagomine derivatives as pharmacological chaperones for the treatment of lysosomal diseases linked to β-galactosidase mutations: Improved synthesis and biological investigations.
Orleans University
Design, synthesis and in vitro study of densely functionalized oxindoles as potent α-glucosidase inhibitors.
Shiv Nadar University
Design, semisynthesis, α-glucosidase inhibitory, cytotoxic, and antibacterial activities of p-terphenyl derivatives.
Ocean University of China
Bioactive Azaphilone Derivatives from the Fungus Talaromyces aculeatus.
Hebei University
Inhibition of protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase by xanthones from Cratoxylum cochinchinense, and their kinetic characterization.
Gyeongsang National University