15 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase.
Lexicon Pharmaceuticals
4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase.
Lexicon Pharmaceuticals
AI-Driven Discovery of Highly Specific and Efficacious hCES2A Inhibitors for Ameliorating Irinotecan-Triggered Gut Toxicity.
Hainan University
Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity.
University College London
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
University College London
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling.
University College London
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity.
University College London
Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity.
University College London
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors.
University College London
Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling.
The Scripps Research Institute
6-amino-2,4-dihydropyrano [2,3-c] pyrazoles and methods of use
Purdue Research Foundation