BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
524401	FC(F)c1cc(ccc1Cl)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H10ClF2N5O/c15-12-3-2-10(6-11(12)13(16)17)22-7-9(20-21-22)8-23-14-18-4-1-5-19-14/h1-7,13H,8H2	YYLHOWLEPPMRSU-UHFFFAOYSA-N	276094	2-((1-(4-Chloro-3-(difluoromethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)-::US10071988, Example 1::US10233173, Example 1	Retinoic acid receptor RXR-alpha	Homo sapiens		 49.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276094&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302255	378157766							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524402	FC(F)Oc1cc(ccc1Cl)-n1cc(CNc2ccccn2)nn1	InChI=1S/C15H12ClF2N5O/c16-12-5-4-11(7-13(12)24-15(17)18)23-9-10(21-22-23)8-20-14-3-1-2-6-19-14/h1-7,9,15H,8H2,(H,19,20)	QVFZWKFTJHULNK-UHFFFAOYSA-N	276095	N-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 2::US10233173, Example 2	Retinoic acid receptor RXR-alpha	Homo sapiens		 213					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276095&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309368	378157767							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524403	Fc1ccc(cc1C(F)(F)F)-n1cc(CNc2ncccn2)nn1	InChI=1S/C14H10F4N6/c15-12-3-2-10(6-11(12)14(16,17)18)24-8-9(22-23-24)7-21-13-19-4-1-5-20-13/h1-6,8H,7H2,(H,19,20,21)	FAWGDTACYVANSD-UHFFFAOYSA-N	276096	N-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 3::US10233173, Example 3	Retinoic acid receptor RXR-alpha	Homo sapiens		 2800					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276096&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309369	378157768							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524404	FC(F)Oc1cc(ccc1F)-n1cc(COc2ccccn2)nn1	InChI=1S/C15H11F3N4O2/c16-12-5-4-11(7-13(12)24-15(17)18)22-8-10(20-21-22)9-23-14-3-1-2-6-19-14/h1-8,15H,9H2	NQSXVBDOPFNNGZ-UHFFFAOYSA-N	276097	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-::US10071988, Example 4::US10233173, Example 4	Retinoic acid receptor RXR-alpha	Homo sapiens		 392					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276097&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309370	378157769							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524405	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2cccnc2)nn1	InChI=1S/C15H11ClF2N4O2/c16-13-4-3-11(6-14(13)24-15(17)18)22-8-10(20-21-22)9-23-12-2-1-5-19-7-12/h1-8,15H,9H2	FSJJMRNDUDYWHK-UHFFFAOYSA-N	276098	3-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 5::US10233173, Example 5	Retinoic acid receptor RXR-alpha	Homo sapiens		 333					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276098&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309372	378157770							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524406	FC(F)c1cccc(c1)-n1cc(CNc2ncccn2)nn1	InChI=1S/C14H12F2N6/c15-13(16)10-3-1-4-12(7-10)22-9-11(20-21-22)8-19-14-17-5-2-6-18-14/h1-7,9,13H,8H2,(H,17,18,19)	KZUZBLIVDLIHPM-UHFFFAOYSA-N	276099	N-((1-(3-(Difluoromethyl)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 6::US10233173, Example 6	Retinoic acid receptor RXR-alpha	Homo sapiens		 10573					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276099&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302187	378157771							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524407	Cn1ccnc1NCc1cn(nn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C14H13F3N6O/c1-22-5-4-18-14(22)19-7-9-8-23(21-20-9)10-2-3-11(15)12(6-10)24-13(16)17/h2-6,8,13H,7H2,1H3,(H,18,19)	AQWHNTMKFNSEPW-UHFFFAOYSA-N	276100	N-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 7::US10233173, Example 7	Retinoic acid receptor RXR-alpha	Homo sapiens		 1870					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276100&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309371	378157772							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524408	Cc1cccc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C16H13F3N4O2/c1-10-3-2-4-15(20-10)24-9-11-8-23(22-21-11)12-5-6-13(17)14(7-12)25-16(18)19/h2-8,16H,9H2,1H3	JHRSKNHYYJXNAP-UHFFFAOYSA-N	276101	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-6-::US10071988, Example 8::US10233173, Example 8	Retinoic acid receptor RXR-alpha	Homo sapiens		 22.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276101&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309373	378157773							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524409	Fc1ccc(cc1Br)-n1cc(COc2ncccn2)nn1	InChI=1S/C13H9BrFN5O/c14-11-6-10(2-3-12(11)15)20-7-9(18-19-20)8-21-13-16-4-1-5-17-13/h1-7H,8H2	DKXZPLYVHRNMFW-UHFFFAOYSA-N	276102	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 9::US10233173, Example 9	Retinoic acid receptor RXR-alpha	Homo sapiens		 20.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276102&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309374	378157774							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524410	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H10ClF2N5O2/c15-11-3-2-10(6-12(11)24-13(16)17)22-7-9(20-21-22)8-23-14-18-4-1-5-19-14/h1-7,13H,8H2	XADXLHOSTVLLIE-UHFFFAOYSA-N	276103	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-::US10071988, Example 10::US10233173, Example 10	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276103&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309375	378157775							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524411	FC(F)c1cc(ccc1Cl)-n1cc(COc2ccccn2)nn1	InChI=1S/C15H11ClF2N4O/c16-13-5-4-11(7-12(13)15(17)18)22-8-10(20-21-22)9-23-14-3-1-2-6-19-14/h1-8,15H,9H2	RVWPNYDSAMTIEQ-UHFFFAOYSA-N	276104	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 11::US10233173, Example 11	Retinoic acid receptor RXR-alpha	Homo sapiens		 1200					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276104&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309376	378157776							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524412	FC(F)c1cc(ccc1Cl)-n1cc(COc2ccncn2)nn1	InChI=1S/C14H10ClF2N5O/c15-12-2-1-10(5-11(12)14(16)17)22-6-9(20-21-22)7-23-13-3-4-18-8-19-13/h1-6,8,14H,7H2	FDUHTVJLMFBSNG-UHFFFAOYSA-N	276105	4-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-::US10071988, Example 12::US10233173, Example 12	Retinoic acid receptor RXR-alpha	Homo sapiens		 2230					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276105&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309377	378157777							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524413	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ccncn2)nn1	InChI=1S/C14H10ClF2N5O2/c15-11-2-1-10(5-12(11)24-14(16)17)22-6-9(20-21-22)7-23-13-3-4-18-8-19-13/h1-6,8,14H,7H2	SPDPFUVSKRIMJV-UHFFFAOYSA-N	276106	4-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 13::US10233173, Example 13	Retinoic acid receptor RXR-alpha	Homo sapiens		 879					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276106&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309378	378157778							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524414	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2cccnn2)nn1	InChI=1S/C14H10ClF2N5O2/c15-11-4-3-10(6-12(11)24-14(16)17)22-7-9(19-21-22)8-23-13-2-1-5-18-20-13/h1-7,14H,8H2	AKHXWEWUJFWZAR-UHFFFAOYSA-N	276107	3-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 14::US10233173, Example 14	Retinoic acid receptor RXR-alpha	Homo sapiens		 401					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276107&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309382	378157779							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524415	COc1cc(ccc1Cl)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H12ClN5O2/c1-21-13-7-11(3-4-12(13)15)20-8-10(18-19-20)9-22-14-16-5-2-6-17-14/h2-8H,9H2,1H3	TYNBZVJUIUCKMN-UHFFFAOYSA-N	276108	2-[[1-(4-Chloro-3-methoxy-phenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 15::US10233173, Example 15	Retinoic acid receptor RXR-alpha	Homo sapiens		 699					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276108&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311673	378157780							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524416	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1	InChI=1S/C14H11BrFN5O/c1-9-5-17-14(18-6-9)22-8-10-7-21(20-19-10)11-2-3-13(16)12(15)4-11/h2-7H,8H2,1H3	RJEWDKWKOWHKIY-UHFFFAOYSA-N	276109	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 16::US10233173, Example 16	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276109&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309379	378157781							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524417	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)n1	InChI=1S/C14H11BrFN5O/c1-9-4-5-17-14(18-9)22-8-10-7-21(20-19-10)11-2-3-13(16)12(15)6-11/h2-7H,8H2,1H3	PEZBPEZARHKLSI-UHFFFAOYSA-N	276110	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-4-methyl-::US10071988, Example 17::US10233173, Example 17	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276110&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309385	378157782							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524418	Cc1cc(C)nc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)n1	InChI=1S/C15H13BrFN5O/c1-9-5-10(2)19-15(18-9)23-8-11-7-22(21-20-11)12-3-4-14(17)13(16)6-12/h3-7H,8H2,1-2H3	JPSAQANRTPTEGO-UHFFFAOYSA-N	276111	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-4,6-dimethyl-::US10071988, Example 18::US10233173, Example 18	Retinoic acid receptor RXR-alpha	Homo sapiens		 82.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276111&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309381	378157783							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524419	Fc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1	InChI=1S/C13H8BrF2N5O/c14-11-3-10(1-2-12(11)16)21-6-9(19-20-21)7-22-13-17-4-8(15)5-18-13/h1-6H,7H2	GVHLOBDAQMTBIU-UHFFFAOYSA-N	276112	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-fluoro-::US10071988, Example 19::US10233173, Example 19	Retinoic acid receptor RXR-alpha	Homo sapiens		 56.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276112&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309387	378157784							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524420	COc1cc(ccc1F)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H12FN5O2/c1-21-13-7-11(3-4-12(13)15)20-8-10(18-19-20)9-22-14-16-5-2-6-17-14/h2-8H,9H2,1H3	AZEMGGARNDOVBK-UHFFFAOYSA-N	276113	2-[[1-(4-Fluoro-3-methoxy-phenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 20::US10233173, Example 20	Retinoic acid receptor RXR-alpha	Homo sapiens		 1000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276113&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311742	378157785							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524421	Cc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C15H12ClF2N5O2/c1-9-4-5-19-15(20-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(6-11)25-14(17)18/h2-7,14H,8H2,1H3	CKXJAQCEYVFZAM-UHFFFAOYSA-N	276114	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-4-methyl-::US10071988, Example 21::US10233173, Example 21	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276114&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309384	378157786							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524422	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C15H12ClF2N5O2/c1-9-5-19-15(20-6-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(4-11)25-14(17)18/h2-7,14H,8H2,1H3	FVPZRFANDLVSCL-UHFFFAOYSA-N	276115	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 22::US10233173, Example 22	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276115&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309388	378157787							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524423	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2cnccn2)nn1	InChI=1S/C14H10ClF2N5O2/c15-11-2-1-10(5-12(11)24-14(16)17)22-7-9(20-21-22)8-23-13-6-18-3-4-19-13/h1-7,14H,8H2	VIGALIAOABUJRA-UHFFFAOYSA-N	276116	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 23::US10233173, Example 23	Retinoic acid receptor RXR-alpha	Homo sapiens		 456					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276116&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309386	378157788							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524424	FC(F)c1cc(ccc1F)-n1cc(CNc2ncccn2)nn1	InChI=1S/C14H11F3N6/c15-12-3-2-10(6-11(12)13(16)17)23-8-9(21-22-23)7-20-14-18-4-1-5-19-14/h1-6,8,13H,7H2,(H,18,19,20)	CZBQMARLVKYCAM-UHFFFAOYSA-N	276117	N-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 24::US10233173, Example 24	Retinoic acid receptor RXR-alpha	Homo sapiens		 824					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276117&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309389	378157789							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524425	FC(F)c1cc(ccc1F)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H10F3N5O/c15-12-3-2-10(6-11(12)13(16)17)22-7-9(20-21-22)8-23-14-18-4-1-5-19-14/h1-7,13H,8H2	ZLEMCSKYAXJAKC-UHFFFAOYSA-N	276118	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 25::US10233173, Example 25	Retinoic acid receptor RXR-alpha	Homo sapiens		 50.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276118&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302373	378157790							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524426	COc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C15H12ClF2N5O3/c1-24-11-5-19-15(20-6-11)25-8-9-7-23(22-21-9)10-2-3-12(16)13(4-10)26-14(17)18/h2-7,14H,8H2,1H3	NARKKHZRYMODKR-UHFFFAOYSA-N	276119	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 26::US10233173, Example 26	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276119&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309390	378157791							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524427	CCc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C16H14ClF2N5O2/c1-2-10-6-20-16(21-7-10)25-9-11-8-24(23-22-11)12-3-4-13(17)14(5-12)26-15(18)19/h3-8,15H,2,9H2,1H3	HCUQIIGPCVXNHB-UHFFFAOYSA-N	276120	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 27::US10233173, Example 27	Retinoic acid receptor RXR-alpha	Homo sapiens		 9.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276120&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309401	378157792							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524428	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H9Cl2F2N5O2/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-11(16)12(3-10)25-13(17)18/h1-6,13H,7H2	ZYIVRWRHTNYLOL-UHFFFAOYSA-N	276121	5-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 28::US10233173, Example 28	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276121&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309391	378157793							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524429	COc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C15H12ClF2N5O3/c1-24-13-4-5-19-15(20-13)25-8-9-7-23(22-21-9)10-2-3-11(16)12(6-10)26-14(17)18/h2-7,14H,8H2,1H3	UBQMQNGMAVJDTM-UHFFFAOYSA-N	276122	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 29::US10233173, Example 29	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276122&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309393	378157794							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524430	Cc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C15H12ClF2N5O/c1-9-4-5-19-15(20-9)24-8-10-7-23(22-21-10)11-2-3-13(16)12(6-11)14(17)18/h2-7,14H,8H2,1H3	HFBJYEDIRNZXFT-UHFFFAOYSA-N	276123	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 30::US10233173, Example 30	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276123&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309392	378157795							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524431	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C15H12ClF2N5O/c1-9-5-19-15(20-6-9)24-8-10-7-23(22-21-10)11-2-3-13(16)12(4-11)14(17)18/h2-7,14H,8H2,1H3	YILFBGPEHUAPIV-UHFFFAOYSA-N	276124	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 154::US10071988, Example 31::US10233173, Example 31	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276124&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309402	378157796							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524432	CCc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C16H14ClF2N5O/c1-2-10-6-20-16(21-7-10)25-9-11-8-24(23-22-11)12-3-4-14(17)13(5-12)15(18)19/h3-8,15H,2,9H2,1H3	WDVWZLRXOFMUKD-UHFFFAOYSA-N	276125	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 32::US10233173, Example 32	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276125&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309394	378157797							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524433	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H10F3N5O2/c15-11-3-2-10(6-12(11)24-13(16)17)22-7-9(20-21-22)8-23-14-18-4-1-5-19-14/h1-7,13H,8H2	KPBZPUGTOGZMQQ-UHFFFAOYSA-N	276126	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 33::US10233173, Example 33	Retinoic acid receptor RXR-alpha	Homo sapiens		 18.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276126&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309398	378157798							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524434	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)cn1	InChI=1S/C15H12ClF2N5O2/c1-9-5-20-14(6-19-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(4-11)25-15(17)18/h2-7,15H,8H2,1H3	WVFYWIMPQAJQSH-UHFFFAOYSA-N	276127	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 34::US10233173, Example 34	Retinoic acid receptor RXR-alpha	Homo sapiens		 159					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276127&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309405	378157799							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524435	FC(F)Oc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C15H10ClF4N5O3/c16-11-2-1-9(3-12(11)28-14(19)20)25-6-8(23-24-25)7-26-15-21-4-10(5-22-15)27-13(17)18/h1-6,13-14H,7H2	BDFSCNUKXJIWPS-UHFFFAOYSA-N	276128	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 35::US10233173, Example 35	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276128&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309396	378157800							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524436	FC(F)Oc1cc(ccc1F)-n1cc(CNc2ncccn2)nn1	InChI=1S/C14H11F3N6O/c15-11-3-2-10(6-12(11)24-13(16)17)23-8-9(21-22-23)7-20-14-18-4-1-5-19-14/h1-6,8,13H,7H2,(H,18,19,20)	VADZTQIJDPWXPG-UHFFFAOYSA-N	276129	N-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 36::US10233173, Example 36	Retinoic acid receptor RXR-alpha	Homo sapiens		 351					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276129&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309397	378157801							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524437	Cc1c(F)ccc(c1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H10ClF2N5O/c1-8-11(16)2-3-12(13(8)17)22-6-10(20-21-22)7-23-14-18-4-9(15)5-19-14/h2-6H,7H2,1H3	YGUBKCJGTOWCMN-UHFFFAOYSA-N	276130	5-Chloro-2-[[1-(2,4-difluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 37::US10233173, Example 37	Retinoic acid receptor RXR-alpha	Homo sapiens		 53.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276130&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309399	378157802							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524438	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)nc1	InChI=1S/C15H13F2N5O/c1-9-5-18-15(19-6-9)23-8-11-7-22(21-20-11)13-4-3-12(16)10(2)14(13)17/h3-7H,8H2,1-2H3	XRQLGIKMUXBVCL-UHFFFAOYSA-N	276131	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 38::US10233173, Example 38	Retinoic acid receptor RXR-alpha	Homo sapiens		 27.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276131&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309403	378157803							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524439	CCc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)nc1	InChI=1S/C16H15F2N5O/c1-3-11-6-19-16(20-7-11)24-9-12-8-23(22-21-12)14-5-4-13(17)10(2)15(14)18/h4-8H,3,9H2,1-2H3	ZGUFFXXBYKKICV-UHFFFAOYSA-N	276132	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-ethyl-::US10071988, Example 39::US10233173, Example 39	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276132&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309400	378157804							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524440	CCc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1	InChI=1S/C15H13BrFN5O/c1-2-10-6-18-15(19-7-10)23-9-11-8-22(21-20-11)12-3-4-14(17)13(16)5-12/h3-8H,2,9H2,1H3	ZANMWPGPVSXQRZ-UHFFFAOYSA-N	276133	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-ethyl-::US10071988, Example 40::US10233173, Example 40	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276133&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309404	378157805							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524441	COc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1	InChI=1S/C14H11BrFN5O2/c1-22-11-5-17-14(18-6-11)23-8-9-7-21(20-19-9)10-2-3-13(16)12(15)4-10/h2-7H,8H2,1H3	BQSLLRKTYVRHJA-UHFFFAOYSA-N	276134	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 41::US10233173, Example 41	Retinoic acid receptor RXR-alpha	Homo sapiens		<1					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276134&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302341	378157806							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524442	Fc1ccc(cc1Br)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C13H8BrClFN5O/c14-11-3-10(1-2-12(11)16)21-6-9(19-20-21)7-22-13-17-4-8(15)5-18-13/h1-6H,7H2	BFBSNMZFDKMQHA-UHFFFAOYSA-N	276135	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-chloro-::US10071988, Example 42::US10233173, Example 42	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276135&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302440	378157807							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524443	CC(C)c1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1	InChI=1S/C16H15BrFN5O/c1-10(2)11-6-19-16(20-7-11)24-9-12-8-23(22-21-12)13-3-4-15(18)14(17)5-13/h3-8,10H,9H2,1-2H3	GPMMBWSCJXNADW-UHFFFAOYSA-N	276136	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-isopropyl-::US10071988, Example 43::US10233173, Example 43	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276136&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309410	378157808							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524444	Fc1ccc(cc1Br)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C14H8BrF4N5O/c15-11-3-10(1-2-12(11)16)24-6-9(22-23-24)7-25-13-20-4-8(5-21-13)14(17,18)19/h1-6H,7H2	KBXGIGNCJXNVAJ-UHFFFAOYSA-N	276137	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-::US10071988, Example 44::US10233173, Example 44	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276137&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309414	378157809							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524445	FC(F)c1cc(ccc1Cl)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H9ClF5N5O/c16-12-2-1-10(3-11(12)13(17)18)26-6-9(24-25-26)7-27-14-22-4-8(5-23-14)15(19,20)21/h1-6,13H,7H2	XPXZGLKWSGMOCA-UHFFFAOYSA-N	276138	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 45::US10233173, Example 45	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276138&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309406	378157810							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524446	COc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C15H12ClF2N5O2/c1-24-11-5-19-15(20-6-11)25-8-9-7-23(22-21-9)10-2-3-13(16)12(4-10)14(17)18/h2-7,14H,8H2,1H3	GWDPYVAVZABLEL-UHFFFAOYSA-N	276139	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 46::US10233173, Example 46	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276139&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309407	378157811							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524447	FC(F)c1cc(ccc1Cl)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H9Cl2F2N5O/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-12(16)11(3-10)13(17)18/h1-6,13H,7H2	KAQSHNAIYKWBTI-UHFFFAOYSA-N	276140	5-Chloro-2-[[1-[4-chloro-3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 47::US10233173, Example 47	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276140&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309411	378157812							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524448	CC(C)c1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C17H16ClF2N5O/c1-10(2)11-6-21-17(22-7-11)26-9-12-8-25(24-23-12)13-3-4-15(18)14(5-13)16(19)20/h3-8,10,16H,9H2,1-2H3	XVOIJMHUFGMZJY-UHFFFAOYSA-N	276141	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 48::US10233173, Example 48	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276141&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309412	378157813							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524449	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H9ClF3N5O/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-12(16)11(3-10)13(17)18/h1-6,13H,7H2	MQLOTQLIWHMPKD-UHFFFAOYSA-N	276142	5-Chloro-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 49::US10233173, Example 49	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276142&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309408	378157814							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524450	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H9F6N5O/c16-12-2-1-10(3-11(12)13(17)18)26-6-9(24-25-26)7-27-14-22-4-8(5-23-14)15(19,20)21/h1-6,13H,7H2	BVYPUXUWWQLMNU-UHFFFAOYSA-N	276143	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 50::US10233173, Example 50	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276143&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309416	378157815							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524451	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C15H12F3N5O/c1-9-5-19-15(20-6-9)24-8-10-7-23(22-21-10)11-2-3-13(16)12(4-11)14(17)18/h2-7,14H,8H2,1H3	HOYXXXFMZLRNFX-UHFFFAOYSA-N	276144	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 51::US10233173, Example 51	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276144	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276144&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302350	378157816							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524452	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C15H12F3N5O/c1-9-4-5-19-15(20-9)24-8-10-7-23(22-21-10)11-2-3-13(16)12(6-11)14(17)18/h2-7,14H,8H2,1H3	HUGMGRNPRIWVLR-UHFFFAOYSA-N	276145	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 52::US10233173, Example 52	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276145&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309409	378157817							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524453	CC(Oc1ncccn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H12ClF2N5O2/c1-9(24-15-19-5-2-6-20-15)12-8-23(22-21-12)10-3-4-11(16)13(7-10)25-14(17)18/h2-9,14H,1H3	WGPIRIWUILWZNN-UHFFFAOYSA-N	276146	(R/S)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 53::US10233173, Example 53	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276146&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309415	378157818							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524454	C[C@@H](Oc1ncccn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H12ClF2N5O2/c1-9(24-15-19-5-2-6-20-15)12-8-23(22-21-12)10-3-4-11(16)13(7-10)25-14(17)18/h2-9,14H,1H3/t9-/m1/s1	WGPIRIWUILWZNN-SECBINFHSA-N	276147	(R*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 374::US10071988, Example 54::US10233173, Example 374	Retinoic acid receptor RXR-alpha	Homo sapiens		 4640					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276147&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302340	378157819							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524455	C[C@H](Oc1ncccn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H12ClF2N5O2/c1-9(24-15-19-5-2-6-20-15)12-8-23(22-21-12)10-3-4-11(16)13(7-10)25-14(17)18/h2-9,14H,1H3/t9-/m0/s1	WGPIRIWUILWZNN-VIFPVBQESA-N	276148	(S*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 378::US10071988, Example 55::US10233173, Example 378	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276148&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302325	378157820							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524456	CC(Oc1ncc(C)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H14ClF2N5O2/c1-9-6-20-16(21-7-9)25-10(2)13-8-24(23-22-13)11-3-4-12(17)14(5-11)26-15(18)19/h3-8,10,15H,1-2H3	QRBOGBACUMUXBQ-UHFFFAOYSA-N	276149	(R/S)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 56::US10233173, Example 56	Retinoic acid receptor RXR-alpha	Homo sapiens		 28.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276149	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276149&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309417	378157821							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524457	C[C@@H](Oc1ncc(C)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H14ClF2N5O2/c1-9-6-20-16(21-7-9)25-10(2)13-8-24(23-22-13)11-3-4-12(17)14(5-11)26-15(18)19/h3-8,10,15H,1-2H3/t10-/m1/s1	QRBOGBACUMUXBQ-SNVBAGLBSA-N	276150	(R*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]ethoxy]-5-methyl-::US10071988, Example 376::US10071988, Example 57::US10233173, Example 376	Retinoic acid receptor RXR-alpha	Homo sapiens		 338					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276150&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302222	378157822							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524458	C[C@H](Oc1ncc(C)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H14ClF2N5O2/c1-9-6-20-16(21-7-9)25-10(2)13-8-24(23-22-13)11-3-4-12(17)14(5-11)26-15(18)19/h3-8,10,15H,1-2H3/t10-/m0/s1	QRBOGBACUMUXBQ-JTQLQIEISA-N	276151	(S*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]ethoxy]-5-methyl-::US10071988, Example 380::US10071988, Example 58::US10233173, Example 380	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276151&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302382	378157823							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524459	CC(Oc1nccc(C)n1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H14ClF2N5O2/c1-9-5-6-20-16(21-9)25-10(2)13-8-24(23-22-13)11-3-4-12(17)14(7-11)26-15(18)19/h3-8,10,15H,1-2H3	ZUXFFTRMULBJMF-UHFFFAOYSA-N	276152	(R/S)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 59::US10233173, Example 59	Retinoic acid receptor RXR-alpha	Homo sapiens		 40.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276152&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309418	378157824							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524460	CC(Oc1ncc(Cl)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H11Cl2F2N5O2/c1-8(25-15-20-5-9(16)6-21-15)12-7-24(23-22-12)10-2-3-11(17)13(4-10)26-14(18)19/h2-8,14H,1H3	WFWPOGDKKNYHRY-UHFFFAOYSA-N	276153	(R/S)-5-Chloro-2-[1-[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 60::US10233173, Example 60	Retinoic acid receptor RXR-alpha	Homo sapiens		 32.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276153&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309419	378157825							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524461	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H9ClF3N5O2/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-11(16)12(3-10)25-13(17)18/h1-6,13H,7H2	FISINIFSVFFLDR-UHFFFAOYSA-N	276154	5-Chloro-2-[[1-[3-(difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 61::US10233173, Example 61	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276154&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309421	378157826							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524462	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H9F6N5O2/c16-11-2-1-10(3-12(11)28-13(17)18)26-6-9(24-25-26)7-27-14-22-4-8(5-23-14)15(19,20)21/h1-6,13H,7H2	DABZUJAFCKHBLJ-UHFFFAOYSA-N	276155	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 62::US10233173, Example 62	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276155&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309422	378157827							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524463	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)nc1	InChI=1S/C15H12F3N5O2/c1-9-5-19-15(20-6-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(4-11)25-14(17)18/h2-7,14H,8H2,1H3	SFJAFALJAQCZQG-UHFFFAOYSA-N	276156	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 63::US10233173, Example 63	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276156	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276156&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309420	378157828							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524464	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C15H12F3N5O2/c1-9-4-5-19-15(20-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(6-11)25-14(17)18/h2-7,14H,8H2,1H3	CJARMIUZBYDZBZ-UHFFFAOYSA-N	276157	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 64::US10233173, Example 64	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276157	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276157&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309423	378157829							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524465	FC(F)c1cc(ccc1F)-n1cc(COc2ccc(cn2)C(F)(F)F)nn1	InChI=1S/C16H10F6N4O/c17-13-3-2-11(5-12(13)15(18)19)26-7-10(24-25-26)8-27-14-4-1-9(6-23-14)16(20,21)22/h1-7,15H,8H2	ZZPYVWZJPDKRCW-UHFFFAOYSA-N	276158	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 65::US10233173, Example 65	Retinoic acid receptor RXR-alpha	Homo sapiens		 56.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276158	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276158&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309424	378157830							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524466	FC(F)c1cc(ccc1Cl)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H9ClF3N5O/c15-12-2-1-10(3-11(12)13(17)18)23-6-9(21-22-23)7-24-14-19-4-8(16)5-20-14/h1-6,13H,7H2	WCHXPALKNXYSRC-UHFFFAOYSA-N	276159	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 66::US10233173, Example 66	Retinoic acid receptor RXR-alpha	Homo sapiens		 52.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276159	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276159&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309425	378157831							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524467	CCc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C17H16F3N5O/c1-3-11-7-21-16(22-8-11)26-10-12-9-25(24-23-12)13-4-5-15(18)14(6-13)17(2,19)20/h4-9H,3,10H2,1-2H3	ZHDYEFOQPVKNEZ-UHFFFAOYSA-N	276160	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 67::US10233173, Example 67	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276160&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309426	378157832							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524468	COc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C16H14F3N5O2/c1-16(18,19)13-5-11(3-4-14(13)17)24-8-10(22-23-24)9-26-15-20-6-12(25-2)7-21-15/h3-8H,9H2,1-2H3	KKYLTBDUOBZNNA-UHFFFAOYSA-N	276161	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 68::US10233173, Example 68	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276161&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309427	378157833							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524469	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C15H11ClF3N5O/c1-15(18,19)12-4-11(2-3-13(12)17)24-7-10(22-23-24)8-25-14-20-5-9(16)6-21-14/h2-7H,8H2,1H3	PKDKTDJSFXDXRS-UHFFFAOYSA-N	276162	5-Chloro-2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 69::US10233173, Example 69	Retinoic acid receptor RXR-alpha	Homo sapiens		 9.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276162&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302414	378157834							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524470	CC(C)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C18H18F3N5O/c1-11(2)12-7-22-17(23-8-12)27-10-13-9-26(25-24-13)14-4-5-16(19)15(6-14)18(3,20)21/h4-9,11H,10H2,1-3H3	KFLZSDFHOGZCSU-UHFFFAOYSA-N	276163	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 70::US10233173, Example 70	Retinoic acid receptor RXR-alpha	Homo sapiens		 44.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276163&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309428	378157835							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524471	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C16H11F6N5O/c1-15(18,19)12-4-11(2-3-13(12)17)27-7-10(25-26-27)8-28-14-23-5-9(6-24-14)16(20,21)22/h2-7H,8H2,1H3	NPZDNOIEXGVUNV-UHFFFAOYSA-N	276164	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 71::US10233173, Example 71	Retinoic acid receptor RXR-alpha	Homo sapiens		 40.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276164&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309429	378157836							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524472	CCc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H13F4N5O/c1-2-10-6-21-15(22-7-10)26-9-11-8-25(24-23-11)12-3-4-14(17)13(5-12)16(18,19)20/h3-8H,2,9H2,1H3	MSGDVUHZBXSXBG-UHFFFAOYSA-N	276165	5-Ethyl-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 72::US10233173, Example 72	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276165&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311759	378157837							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524473	COc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C15H11F4N5O2/c1-25-11-5-20-14(21-6-11)26-8-9-7-24(23-22-9)10-2-3-13(16)12(4-10)15(17,18)19/h2-7H,8H2,1H3	XCUKVGWLZKGMBA-UHFFFAOYSA-N	276166	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 73::US10233173, Example 73	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276166&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311752	378157838							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524474	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H8ClF4N5O/c15-8-4-20-13(21-5-8)25-7-9-6-24(23-22-9)10-1-2-12(16)11(3-10)14(17,18)19/h1-6H,7H2	ZAXXZIIEMQQUDO-UHFFFAOYSA-N	276167	5-Chloro-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 74::US10233173, Example 74	Retinoic acid receptor RXR-alpha	Homo sapiens		 16.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276167&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311800	378157839							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524475	CC(C)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C17H15F4N5O/c1-10(2)11-6-22-16(23-7-11)27-9-12-8-26(25-24-12)13-3-4-15(18)14(5-13)17(19,20)21/h3-8,10H,9H2,1-2H3	WBKOUVTZNBJQEP-UHFFFAOYSA-N	276168	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 75::US10233173, Example 75	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276168&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311754	378157840							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524476	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H8F7N5O/c16-12-2-1-10(3-11(12)15(20,21)22)27-6-9(25-26-27)7-28-13-23-4-8(5-24-13)14(17,18)19/h1-6H,7H2	PCOBRQITWVGTCG-UHFFFAOYSA-N	276169	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 76::US10233173, Example 76	Retinoic acid receptor RXR-alpha	Homo sapiens		 35.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276169&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311753	378157841							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524477	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C16H14F3N5O/c1-10-6-20-15(21-7-10)25-9-11-8-24(23-22-11)12-3-4-14(17)13(5-12)16(2,18)19/h3-8H,9H2,1-2H3	UVNKBHYJPIJAII-UHFFFAOYSA-N	276170	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 77::US10233173, Example 77	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276170&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309435	378157842							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524478	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncccn2)nn1	InChI=1S/C15H12F3N5O/c1-15(17,18)12-7-11(3-4-13(12)16)23-8-10(21-22-23)9-24-14-19-5-2-6-20-14/h2-8H,9H2,1H3	ZMJLRLXYGFASGN-UHFFFAOYSA-N	276171	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 78::US10233173, Example 78	Retinoic acid receptor RXR-alpha	Homo sapiens		 60.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276171&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309438	378157843							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524479	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)n1	InChI=1S/C16H14F3N5O/c1-10-5-6-20-15(21-10)25-9-11-8-24(23-22-11)12-3-4-14(17)13(7-12)16(2,18)19/h3-8H,9H2,1-2H3	OFHJAZXWLTUXLX-UHFFFAOYSA-N	276172	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 79::US10233173, Example 79	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276172&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309436	378157844							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524480	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C15H11F4N5O/c1-15(18,19)12-4-11(2-3-13(12)17)24-7-10(22-23-24)8-25-14-20-5-9(16)6-21-14/h2-7H,8H2,1H3	BIAIXZOAJTVRMZ-UHFFFAOYSA-N	276173	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 80::US10233173, Example 80	Retinoic acid receptor RXR-alpha	Homo sapiens		 32.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276173&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309437	378157845							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524481	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C15H11F4N5O/c1-9-5-20-14(21-6-9)25-8-10-7-24(23-22-10)11-2-3-13(16)12(4-11)15(17,18)19/h2-7H,8H2,1H3	HCENSGGANKMNMX-UHFFFAOYSA-N	276174	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 81::US10233173, Example 81	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276174&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311714	378157846							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524482	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H9F4N5O/c15-12-3-2-10(6-11(12)14(16,17)18)23-7-9(21-22-23)8-24-13-19-4-1-5-20-13/h1-7H,8H2	IRZMOPZJYJJMLN-UHFFFAOYSA-N	276175	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 82::US10233173, Example 82	Retinoic acid receptor RXR-alpha	Homo sapiens		 126					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276175&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309439	378157847							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524483	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)n1	InChI=1S/C15H11F4N5O/c1-9-4-5-20-14(21-9)25-8-10-7-24(23-22-10)11-2-3-13(16)12(6-11)15(17,18)19/h2-7H,8H2,1H3	FACDZFOPTMUZIF-UHFFFAOYSA-N	276176	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 83::US10233173, Example 83	Retinoic acid receptor RXR-alpha	Homo sapiens		 20.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276176&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311801	378157848							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524484	Fc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C14H8F5N5O/c15-8-4-20-13(21-5-8)25-7-9-6-24(23-22-9)10-1-2-12(16)11(3-10)14(17,18)19/h1-6H,7H2	CBHPTKGCZAZVNB-UHFFFAOYSA-N	276177	5-Fuoro-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 84::US10233173, Example 84	Retinoic acid receptor RXR-alpha	Homo sapiens		 72.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276177&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311713	378157849							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524485	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1C	InChI=1S/C15H13BrFN5O/c1-9-6-18-15(19-10(9)2)23-8-11-7-22(21-20-11)12-3-4-14(17)13(16)5-12/h3-7H,8H2,1-2H3	YIDWIIAVSOZDQA-UHFFFAOYSA-N	276178	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-4,5-dimethyl-pyrimidine;::US10071988, Example 85::US10233173, Example 85	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276178&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309442	378157850							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524486	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1C	InChI=1S/C16H14ClF2N5O/c1-9-6-20-16(21-10(9)2)25-8-11-7-24(23-22-11)12-3-4-14(17)13(5-12)15(18)19/h3-7,15H,8H2,1-2H3	JCLHGSAIJXKOKT-UHFFFAOYSA-N	276179	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4,5-::US10071988, Example 86::US10233173, Example 86	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276179&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309444	378157851							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524487	COc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC)c2)nc1	InChI=1S/C15H14ClN5O3/c1-22-12-6-17-15(18-7-12)24-9-10-8-21(20-19-10)11-3-4-13(16)14(5-11)23-2/h3-8H,9H2,1-2H3	NZJJADGNWJARNM-UHFFFAOYSA-N	276180	2-[[1-(4-Chloro-3-methoxy-phenyl)triazol-4-yl]methoxy]-5-methoxy-pyrimidine;::US10071988, Example 87::US10233173, Example 87	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276180&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311760	378157852							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524488	COc1cc(ccc1Cl)-n1cc(COc2ncc(C)cn2)nn1	InChI=1S/C15H14ClN5O2/c1-10-6-17-15(18-7-10)23-9-11-8-21(20-19-11)12-3-4-13(16)14(5-12)22-2/h3-8H,9H2,1-2H3	BWIPJPQTFRATND-UHFFFAOYSA-N	276181	2-[[1-(4-Chloro-3-methoxy-phenyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 88::US10233173, Example 88	Retinoic acid receptor RXR-alpha	Homo sapiens		 19.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276181&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311761	378157853							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524489	Cc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1	InChI=1S/C15H13F2N5O/c1-10-6-18-15(19-7-10)23-9-12-8-22(21-20-12)13-4-2-3-11(5-13)14(16)17/h2-8,14H,9H2,1H3	OTZUCMMSLKQSFK-UHFFFAOYSA-N	276182	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 89::US10233173, Example 89	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276182&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309450	378157854							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524490	COc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1	InChI=1S/C15H13F2N5O2/c1-23-13-6-18-15(19-7-13)24-9-11-8-22(21-20-11)12-4-2-3-10(5-12)14(16)17/h2-8,14H,9H2,1H3	NEIYCKBYRUFHGX-UHFFFAOYSA-N	276183	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-methoxy-pyrimidine;::US10071988, Example 90::US10233173, Example 90	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276183&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309447	378157855							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524491	CCc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1	InChI=1S/C16H15F2N5O/c1-2-11-7-19-16(20-8-11)24-10-13-9-23(22-21-13)14-5-3-4-12(6-14)15(17)18/h3-9,15H,2,10H2,1H3	QNADXEFNAUJUAR-UHFFFAOYSA-N	276184	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-ethyl-pyrimidine;::US10071988, Example 91::US10233173, Example 91	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276184&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309448	378157856							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524492	FC(F)c1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H10ClF2N5O/c15-10-5-18-14(19-6-10)23-8-11-7-22(21-20-11)12-3-1-2-9(4-12)13(16)17/h1-7,13H,8H2	JOHBQCKBUUFKIS-UHFFFAOYSA-N	276185	5-Chloro-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 153::US10071988, Example 92::US10233173, Example 92	Retinoic acid receptor RXR-alpha	Homo sapiens		 19.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276185&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309449	378157857							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524493	FC(F)c1cccc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H11F2N5O/c15-13(16)10-3-1-4-12(7-10)21-8-11(19-20-21)9-22-14-17-5-2-6-18-14/h1-8,13H,9H2	FWNDYWYVWNXOJU-UHFFFAOYSA-N	276186	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 93::US10233173, Example 93	Retinoic acid receptor RXR-alpha	Homo sapiens		 493					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276186&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309451	378157858							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524494	Cc1cnc(OCc2cn(nn2)-c2ccc(Br)c(C)c2)nc1	InChI=1S/C15H14BrN5O/c1-10-6-17-15(18-7-10)22-9-12-8-21(20-19-12)13-3-4-14(16)11(2)5-13/h3-8H,9H2,1-2H3	SEWPCJDHGFYKLK-UHFFFAOYSA-N	276187	2-[[1-(5-Bromo-6-methyl-2-pyridyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 94	Retinoic acid receptor RXR-alpha	Homo sapiens		 2910					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276187&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309452	378157859							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524495	FC(F)Oc1cc(ccc1Br)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H9BrF3N5O2/c15-11-2-1-10(3-12(11)25-13(17)18)23-6-9(21-22-23)7-24-14-19-4-8(16)5-20-14/h1-6,13H,7H2	GDFWABUNFQIZIO-UHFFFAOYSA-N	276188	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 95	Retinoic acid receptor RXR-alpha	Homo sapiens		 23.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276188&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309453	378157860							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524496	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(cn2)C(F)F)nn1	InChI=1S/C15H10ClF4N5O2/c16-11-2-1-10(3-12(11)27-14(19)20)25-6-9(23-24-25)7-26-15-21-4-8(5-22-15)13(17)18/h1-6,13-14H,7H2	POXGNDTXJNUNKV-UHFFFAOYSA-N	276189	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 96::US10233173, Example 96	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276189&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309454	378157861							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524497	FC(F)Oc1cc(ccc1Cl)-n1cc(CNc2ncco2)nn1	InChI=1S/C13H10ClF2N5O2/c14-10-2-1-9(5-11(10)23-12(15)16)21-7-8(19-20-21)6-18-13-17-3-4-22-13/h1-5,7,12H,6H2,(H,17,18)	NMHURWAAXYDILD-UHFFFAOYSA-N	276190	N-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 97::US10233173, Example 97	Retinoic acid receptor RXR-alpha	Homo sapiens		 106					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276190&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309459	378157862							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524498	FC(F)Oc1cc(ccc1Cl)-n1cc(CNc2ncccn2)nn1	InChI=1S/C14H11ClF2N6O/c15-11-3-2-10(6-12(11)24-13(16)17)23-8-9(21-22-23)7-20-14-18-4-1-5-19-14/h1-6,8,13H,7H2,(H,18,19,20)	XSJRFPPGWLDKML-UHFFFAOYSA-N	276191	N-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 98::US10233173, Example 98	Retinoic acid receptor RXR-alpha	Homo sapiens		 331					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276191&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309456	378157863							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524499	Cn1cc(NCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)cn1	InChI=1S/C14H13F3N6/c1-22-7-9(6-19-22)18-5-10-8-23(21-20-10)11-2-3-13(15)12(4-11)14(16)17/h2-4,6-8,14,18H,5H2,1H3	HDESGBDDHNSEMG-UHFFFAOYSA-N	276192	N-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 99::US10233173, Example 99	Retinoic acid receptor RXR-alpha	Homo sapiens		 5050					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276192&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309455	378157864							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524500	Cn1ccc(NCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C14H13F3N6/c1-22-5-4-13(20-22)18-7-9-8-23(21-19-9)10-2-3-12(15)11(6-10)14(16)17/h2-6,8,14H,7H2,1H3,(H,18,20)	SKUGIXWAKLKUGW-UHFFFAOYSA-N	276193	N-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 100::US10233173, Example 100	Retinoic acid receptor RXR-alpha	Homo sapiens		 894					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276193&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309457	378157865							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524501	Cn1ccc(NCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C14H13F3N6O/c1-22-5-4-13(20-22)18-7-9-8-23(21-19-9)10-2-3-11(15)12(6-10)24-14(16)17/h2-6,8,14H,7H2,1H3,(H,18,20)	RBROFAWZOZCILM-UHFFFAOYSA-N	276194	N-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 101::US10233173, Example 101	Retinoic acid receptor RXR-alpha	Homo sapiens		 374					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276194&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309458	378157866							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524502	Cn1cc(NCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)cn1	InChI=1S/C14H13F3N6O/c1-22-7-9(6-19-22)18-5-10-8-23(21-20-10)11-2-3-12(15)13(4-11)24-14(16)17/h2-4,6-8,14,18H,5H2,1H3	PZKYEJMFTZQOCR-UHFFFAOYSA-N	276195	N-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 102::US10233173, Example 102	Retinoic acid receptor RXR-alpha	Homo sapiens		 3250					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276195&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309462	378157867							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524503	COc1ncccc1OCc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H13ClF2N4O3/c1-24-15-13(3-2-6-20-15)25-9-10-8-23(22-21-10)11-4-5-12(17)14(7-11)26-16(18)19/h2-8,16H,9H2,1H3	XRVXBANLXMKGNC-UHFFFAOYSA-N	276196	3-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-2-::US10071988, Example 103::US10233173, Example 103	Retinoic acid receptor RXR-alpha	Homo sapiens		 64.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276196&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309460	378157868							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524504	Cc1ccc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)cn1	InChI=1S/C16H13ClF2N4O2/c1-10-2-4-13(7-20-10)24-9-11-8-23(22-21-11)12-3-5-14(17)15(6-12)25-16(18)19/h2-8,16H,9H2,1H3	GCGLGJCWZRAPAO-UHFFFAOYSA-N	276197	5-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-2-::US10071988, Example 104::US10233173, Example 104	Retinoic acid receptor RXR-alpha	Homo sapiens		 729					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276197&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309461	378157869							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524505	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncccc2Cl)nn1	InChI=1S/C15H10Cl2F2N4O2/c16-11-4-3-10(6-13(11)25-15(18)19)23-7-9(21-22-23)8-24-14-12(17)2-1-5-20-14/h1-7,15H,8H2	GMJZDKUFVFUCIX-UHFFFAOYSA-N	276198	3-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 105::US10233173, Example 105	Retinoic acid receptor RXR-alpha	Homo sapiens		 59.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276198&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309464	378157870							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524506	COc1cc(Cl)cnc1OCc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H12Cl2F2N4O3/c1-25-14-4-9(17)6-21-15(14)26-8-10-7-24(23-22-10)11-2-3-12(18)13(5-11)27-16(19)20/h2-7,16H,8H2,1H3	VMJXOGWQELFZKA-UHFFFAOYSA-N	276199	5-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 106::US10233173, Example 106	Retinoic acid receptor RXR-alpha	Homo sapiens		 276					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276199&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311755	378157871							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524507	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncccc2F)nn1	InChI=1S/C15H10ClF3N4O2/c16-11-4-3-10(6-13(11)25-15(18)19)23-7-9(21-22-23)8-24-14-12(17)2-1-5-20-14/h1-7,15H,8H2	FGWCIRNMKJVCMM-UHFFFAOYSA-N	276200	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-3-::US10071988, Example 107::US10233173, Example 107	Retinoic acid receptor RXR-alpha	Homo sapiens		 119					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276200&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309463	378157872							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524508	COc1cccnc1OCc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H13ClF2N4O3/c1-24-13-3-2-6-20-15(13)25-9-10-8-23(22-21-10)11-4-5-12(17)14(7-11)26-16(18)19/h2-8,16H,9H2,1H3	WJKRTHUIEIZHFO-UHFFFAOYSA-N	276201	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-3-::US10071988, Example 108::US10233173, Example 108	Retinoic acid receptor RXR-alpha	Homo sapiens		 114					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276201&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130311715	378157873							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524509	FC(F)c1cc(ccc1Cl)-n1cc(CNc2ncccn2)nn1	InChI=1S/C14H11ClF2N6/c15-12-3-2-10(6-11(12)13(16)17)23-8-9(21-22-23)7-20-14-18-4-1-5-19-14/h1-6,8,13H,7H2,(H,18,19,20)	ZLBVELNRVLGPDW-UHFFFAOYSA-N	276202	N-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 109::US10233173, Example 109	Retinoic acid receptor RXR-alpha	Homo sapiens		 1260					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276202&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309468	378157874							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524510	FC(F)c1cc(ccc1Cl)-n1cc(CNc2ccncn2)nn1	InChI=1S/C14H11ClF2N6/c15-12-2-1-10(5-11(12)14(16)17)23-7-9(21-22-23)6-19-13-3-4-18-8-20-13/h1-5,7-8,14H,6H2,(H,18,19,20)	COPNRWBBVBWKFD-UHFFFAOYSA-N	276203	N-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 110::US10233173, Example 110	Retinoic acid receptor RXR-alpha	Homo sapiens		 7570					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276203&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309466	378157875							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524511	FC(F)c1cc(ccc1F)-n1cc(COc2ccccn2)nn1	InChI=1S/C15H11F3N4O/c16-13-5-4-11(7-12(13)15(17)18)22-8-10(20-21-22)9-23-14-3-1-2-6-19-14/h1-8,15H,9H2	IXQKYHFDBVQCRG-UHFFFAOYSA-N	276204	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 111::US10233173, Example 111	Retinoic acid receptor RXR-alpha	Homo sapiens		 684					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276204&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309471	378157876							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524512	FC(F)c1cc(ccc1F)-n1cc(COc2ccc(Cl)cn2)nn1	InChI=1S/C15H10ClF3N4O/c16-9-1-4-14(20-6-9)24-8-10-7-23(22-21-10)11-2-3-13(17)12(5-11)15(18)19/h1-7,15H,8H2	TXKOLHISXQEJFK-UHFFFAOYSA-N	276205	5-Chloro-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 112::US10233173, Example 112	Retinoic acid receptor RXR-alpha	Homo sapiens		 56.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276205&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309469	378157877							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524513	Cc1cccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C16H13F3N4O/c1-10-3-2-4-15(20-10)24-9-11-8-23(22-21-11)12-5-6-14(17)13(7-12)16(18)19/h2-8,16H,9H2,1H3	RQFODQBXSXAFLK-UHFFFAOYSA-N	276206	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-6-::US10071988, Example 113::US10233173, Example 113	Retinoic acid receptor RXR-alpha	Homo sapiens		 38.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276206&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309470	378157878							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524514	Cc1ccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C16H13F3N4O/c1-10-2-5-15(20-7-10)24-9-11-8-23(22-21-11)12-3-4-14(17)13(6-12)16(18)19/h2-8,16H,9H2,1H3	NIZZMQDOTNELNI-UHFFFAOYSA-N	276207	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 114::US10233173, Example 114	Retinoic acid receptor RXR-alpha	Homo sapiens		 21.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276207&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309472	378157879							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524515	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)c1	InChI=1S/C16H13F3N4O/c1-10-4-5-20-15(6-10)24-9-11-8-23(22-21-11)12-2-3-14(17)13(7-12)16(18)19/h2-8,16H,9H2,1H3	KBFRSEKVZXJLJU-UHFFFAOYSA-N	276208	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 115::US10233173, Example 115	Retinoic acid receptor RXR-alpha	Homo sapiens		 170					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276208&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309473	378157880							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524516	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)c1	InChI=1S/C16H13F3N4O2/c1-10-4-5-20-15(6-10)24-9-11-8-23(22-21-11)12-2-3-13(17)14(7-12)25-16(18)19/h2-8,16H,9H2,1H3	SQVJPWXQMLPLKF-UHFFFAOYSA-N	276209	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 116::US10233173, Example 116	Retinoic acid receptor RXR-alpha	Homo sapiens		 102					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276209	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276209&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309474	378157881							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524517	FC(F)Oc1cc(ccc1F)-n1cc(COc2ccc(Cl)cn2)nn1	InChI=1S/C15H10ClF3N4O2/c16-9-1-4-14(20-6-9)24-8-10-7-23(22-21-10)11-2-3-12(17)13(5-11)25-15(18)19/h1-7,15H,8H2	SDOHPDNTDYKAKH-UHFFFAOYSA-N	276210	5-Chloro-2-[[1-[3-(difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 117::US10233173, Example 117	Retinoic acid receptor RXR-alpha	Homo sapiens		 73.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276210&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302402	378157882							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524518	Cc1ccc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)nc1	InChI=1S/C16H13F3N4O2/c1-10-2-5-15(20-7-10)24-9-11-8-23(22-21-11)12-3-4-13(17)14(6-12)25-16(18)19/h2-8,16H,9H2,1H3	YNNZXZMVRLYSIA-UHFFFAOYSA-N	276211	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 118::US10233173, Example 118	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276211	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276211&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309475	378157883							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524519	FC(F)Oc1cc(ccc1F)-n1cc(COc2ccc(cn2)C(F)(F)F)nn1	InChI=1S/C16H10F6N4O2/c17-12-3-2-11(5-13(12)28-15(18)19)26-7-10(24-25-26)8-27-14-4-1-9(6-23-14)16(20,21)22/h1-7,15H,8H2	BHASXNIDNFEQDU-UHFFFAOYSA-N	276212	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 119::US10233173, Example 119	Retinoic acid receptor RXR-alpha	Homo sapiens		 114					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276212&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309483	378157884							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524520	Cc1cnc(OCc2cn(nn2)-c2ccc(s2)C(F)(F)F)nc1	InChI=1S/C13H10F3N5OS/c1-8-4-17-12(18-5-8)22-7-9-6-21(20-19-9)11-3-2-10(23-11)13(14,15)16/h2-6H,7H2,1H3	FMLUXSHALWTMEO-UHFFFAOYSA-N	276213	5-Methyl-2-((1-(5-(trifluoromethyl)thiophen-2-yl)-1H-1,2,3-triazol-4-::US10071988, Example 120::US10233173, Example 120	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276213&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302246	378157885							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524521	Cc1c(COc2ncc(C)cn2)nnn1-c1cccc(c1)C(F)F	InChI=1S/C16H15F2N5O/c1-10-7-19-16(20-8-10)24-9-14-11(2)23(22-21-14)13-5-3-4-12(6-13)15(17)18/h3-8,15H,9H2,1-2H3	VCMPLIZYKYHCOI-UHFFFAOYSA-N	276214	2-((1-(3-(Difluoromethyl)phenyl)-5-methyl-1H-1,2,3-triazol-4-::US10071988, Example 149::US10233173, Example 149	Retinoic acid receptor RXR-alpha	Homo sapiens		 952					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276214&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302262	378157886							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524522	FC(F)c1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H10ClF2N5O/c15-10-5-18-14(19-6-10)23-8-11-7-22(21-20-11)12-3-1-2-9(4-12)13(16)17/h1-7,13H,8H2	JOHBQCKBUUFKIS-UHFFFAOYSA-N	276185	5-Chloro-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 153::US10071988, Example 92::US10233173, Example 92	Retinoic acid receptor RXR-alpha	Homo sapiens		 216					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276185&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309449	378157857							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524523	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C15H12ClF2N5O/c1-9-5-19-15(20-6-9)24-8-10-7-23(22-21-10)11-2-3-13(16)12(4-11)14(17)18/h2-7,14H,8H2,1H3	YILFBGPEHUAPIV-UHFFFAOYSA-N	276124	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 154::US10071988, Example 31::US10233173, Example 31	Retinoic acid receptor RXR-alpha	Homo sapiens		 30.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276124&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309402	378157796							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524524	Cc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1C	InChI=1S/C16H15F2N5O/c1-10-7-19-16(20-11(10)2)24-9-13-8-23(22-21-13)14-5-3-4-12(6-14)15(17)18/h3-8,15H,9H2,1-2H3	PZMQRZXEZSRGNQ-UHFFFAOYSA-N	276217	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-4,5-dimethyl-::US10071988, Example 155::US10233173, Example 155	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276217&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309497	378157887							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524525	CC(=O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C16H12F3N5O2/c1-9(25)10-5-20-16(21-6-10)26-8-11-7-24(23-22-11)12-2-3-14(17)13(4-12)15(18)19/h2-7,15H,8H2,1H3	NQZJXXLTQRRRLW-UHFFFAOYSA-N	276218	1-[2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 156::US10233173, Example 156	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276218&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309498	378157888							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524526	CC(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C16H14F3N5O2/c1-9(25)10-5-20-16(21-6-10)26-8-11-7-24(23-22-11)12-2-3-14(17)13(4-12)15(18)19/h2-7,9,15,25H,8H2,1H3	MLPNETALLNFUNL-UHFFFAOYSA-N	276219	(R/S)-1-[2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 157::US10233173, Example 157	Retinoic acid receptor RXR-alpha	Homo sapiens		 18.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276219&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309499	378157889							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524527	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ccccn2)nn1	InChI=1S/C15H10F4N4O/c16-13-5-4-11(7-12(13)15(17,18)19)23-8-10(21-22-23)9-24-14-3-1-2-6-20-14/h1-8H,9H2	XWUXFHFFQMKCIF-UHFFFAOYSA-N	276220	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 158::US10233173, Example 158	Retinoic acid receptor RXR-alpha	Homo sapiens		 3040					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276220	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276220&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309500	378157890							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524528	OCc1ccnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)n1	InChI=1S/C15H13F2N5O2/c16-14(17)10-2-1-3-13(6-10)22-7-12(20-21-22)9-24-15-18-5-4-11(8-23)19-15/h1-7,14,23H,8-9H2	RWMASHRJKARNFY-UHFFFAOYSA-N	276221	US10071988, Example 159::US10233173, Example 159::[2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 408					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276221	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276221&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309506	378157891							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524529	OCc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1	InChI=1S/C15H13F2N5O2/c16-14(17)11-2-1-3-13(4-11)22-7-12(20-21-22)9-24-15-18-5-10(8-23)6-19-15/h1-7,14,23H,8-9H2	FNFMFGPECXHILK-UHFFFAOYSA-N	276222	US10071988, Example 160::US10233173, Example 160::[2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-5-	Retinoic acid receptor RXR-alpha	Homo sapiens		 173					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276222	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276222&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309501	378157892							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524530	Cc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1N	InChI=1S/C15H14F2N6O/c1-9-6-19-15(20-14(9)18)24-8-11-7-23(22-21-11)12-4-2-3-10(5-12)13(16)17/h2-7,13H,8H2,1H3,(H2,18,19,20)	AAXZTRYJVZCLCT-UHFFFAOYSA-N	276223	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 161::US10233173, Example 161	Retinoic acid receptor RXR-alpha	Homo sapiens		 55.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276223	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276223&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309502	378157893							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524531	CNC(=O)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C16H13F3N6O2/c1-20-15(26)13-4-5-21-16(22-13)27-8-9-7-25(24-23-9)10-2-3-12(17)11(6-10)14(18)19/h2-7,14H,8H2,1H3,(H,20,26)	SMMRHEAXRCHUKZ-UHFFFAOYSA-N	276224	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 162::US10233173, Example 162	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276224&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309503	378157894							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524532	CC(N)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(CC(F)F)c2)n1	InChI=1S/C17H17F3N6O/c1-10(21)15-4-5-22-17(23-15)27-9-12-8-26(25-24-12)13-2-3-14(18)11(6-13)7-16(19)20/h2-6,8,10,16H,7,9,21H2,1H3	VFYZEFWCCARIKA-UHFFFAOYSA-N	276225	(R/S) 1-[2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 163	Retinoic acid receptor RXR-alpha	Homo sapiens		 1400					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276225	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276225&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309504	378157895							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524533	Fc1ccc(cc1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C13H9ClFN5O/c14-9-5-16-13(17-6-9)21-8-11-7-20(19-18-11)12-3-1-10(15)2-4-12/h1-7H,8H2	ZDQTWPGWFJQXAY-UHFFFAOYSA-N	276226	5-Chloro-2-[[1-(4-fluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 164::US10233173, Example 164	Retinoic acid receptor RXR-alpha	Homo sapiens		 371					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276226&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309505	378157896							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524534	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CCC2)nn1	InChI=1S/C17H15F3N6O2/c18-14-3-2-12(6-15(14)28-16(19)20)26-9-11(23-24-26)10-27-17-21-7-13(8-22-17)25-4-1-5-25/h2-3,6-9,16H,1,4-5,10H2	LYTXTYPRIVRMHZ-UHFFFAOYSA-N	276227	5-(Azetidin-1-yl)-2-[[1-[3-(difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 165::US10233173, Example 165	Retinoic acid receptor RXR-alpha	Homo sapiens		 16.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276227&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309507	378157897							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524535	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CCC(F)(F)C2)nn1	InChI=1S/C18H15F5N6O2/c19-13-2-1-12(7-14(13)31-16(20)21)29-8-11(26-27-29)9-30-17-24-5-3-15(25-17)28-6-4-18(22,23)10-28/h1-3,5,7-8,16H,4,6,9-10H2	QIUHWGIDQVQWTK-UHFFFAOYSA-N	276228	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 166::US10233173, Example 166	Retinoic acid receptor RXR-alpha	Homo sapiens		 144					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276228&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309508	378157898							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524536	Nc1nc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)ncc1F	InChI=1S/C14H10F4N6O2/c15-9-2-1-8(3-11(9)26-13(17)18)24-5-7(22-23-24)6-25-14-20-4-10(16)12(19)21-14/h1-5,13H,6H2,(H2,19,20,21)	ADCGOKWENZQQJQ-UHFFFAOYSA-N	276229	2-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 167::US10233173, Example 167	Retinoic acid receptor RXR-alpha	Homo sapiens		 13.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276229&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302351	378157899							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524537	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CCCC2)nn1	InChI=1S/C18H17F3N6O2/c19-14-4-3-13(9-15(14)29-17(20)21)27-10-12(24-25-27)11-28-18-22-6-5-16(23-18)26-7-1-2-8-26/h3-6,9-10,17H,1-2,7-8,11H2	MGJJUFTZBPRVRP-UHFFFAOYSA-N	276230	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 168::US10233173, Example 168	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276230&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309510	378157900							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524538	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CCCCC2)nn1	InChI=1S/C19H19F3N6O2/c20-15-5-4-14(10-16(15)30-18(21)22)28-11-13(25-26-28)12-29-19-23-7-6-17(24-19)27-8-2-1-3-9-27/h4-7,10-11,18H,1-3,8-9,12H2	OFDCWBLZQJRQNC-UHFFFAOYSA-N	276231	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-(1-::US10071988, Example 169::US10233173, Example 169	Retinoic acid receptor RXR-alpha	Homo sapiens		 31.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276231&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309509	378157901							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524539	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CCOCC2)nn1	InChI=1S/C18H17F3N6O3/c19-14-2-1-13(9-15(14)30-17(20)21)27-10-12(24-25-27)11-29-18-22-4-3-16(23-18)26-5-7-28-8-6-26/h1-4,9-10,17H,5-8,11H2	RIDLCGNQFAFGJR-UHFFFAOYSA-N	276232	4-[2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 170::US10233173, Example 170	Retinoic acid receptor RXR-alpha	Homo sapiens		 260					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276232&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309511	378157902							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524540	CNc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C15H13ClF2N6O2/c1-19-13-4-5-20-15(21-13)25-8-9-7-24(23-22-9)10-2-3-11(16)12(6-10)26-14(17)18/h2-7,14H,8H2,1H3,(H,19,20,21)	PBKPSCDANWPCBF-UHFFFAOYSA-N	276233	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 171::US10233173, Example 171	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276233	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276233&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309512	378157903							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524541	COc1cnc(OCc2nnn(c2C)-c2cccc(c2)C(F)F)nc1	InChI=1S/C16H15F2N5O2/c1-10-14(9-25-16-19-7-13(24-2)8-20-16)21-22-23(10)12-5-3-4-11(6-12)15(17)18/h3-8,15H,9H2,1-2H3	ZXDBMIGBUUYXKE-UHFFFAOYSA-N	276234	2-[[1-[3-(Difluoromethyl)phenyl]-5-methyl-triazol-4-yl]methoxy]-5-::US10071988, Example 172::US10233173, Example 172	Retinoic acid receptor RXR-alpha	Homo sapiens		 468					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276234&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309514	378157904							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524542	Cc1c(COc2ncc(C)cn2)nnn1-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C17H16F3N5O/c1-10-7-21-16(22-8-10)26-9-15-11(2)25(24-23-15)12-4-5-14(18)13(6-12)17(3,19)20/h4-8H,9H2,1-3H3	BGRBDJSGMGDLSA-UHFFFAOYSA-N	276235	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]-5-methyl-triazol-4-::US10071988, Example 173::US10233173, Example 173	Retinoic acid receptor RXR-alpha	Homo sapiens		 465					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276235&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309513	378157905							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524543	Cc1cnc(OCc2cn(nn2)-c2cccc(C)n2)nc1	InChI=1S/C14H14N6O/c1-10-6-15-14(16-7-10)21-9-12-8-20(19-18-12)13-5-3-4-11(2)17-13/h3-8H,9H2,1-2H3	ZKQDXZFLJJCJDS-UHFFFAOYSA-N	276236	5-Methyl-2-[[1-(6-methyl-2-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 174::US10233173, Example 174	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276236	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276236&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309515	378157906							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524544	Cc1cnc(OCc2cn(nn2)-c2ccnc(C)c2)nc1	InChI=1S/C14H14N6O/c1-10-6-16-14(17-7-10)21-9-12-8-20(19-18-12)13-3-4-15-11(2)5-13/h3-8H,9H2,1-2H3	ZDNSEOYRLXQGFM-UHFFFAOYSA-N	276237	5-Methyl-2-[[1-(2-methyl-4-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 175::US10233173, Example 175	Retinoic acid receptor RXR-alpha	Homo sapiens		 655					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276237&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309516	378157907							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524545	Cc1cnc(OCc2cn(nn2)-c2cncc(C)c2)nc1	InChI=1S/C14H14N6O/c1-10-3-13(7-15-4-10)20-8-12(18-19-20)9-21-14-16-5-11(2)6-17-14/h3-8H,9H2,1-2H3	LFUZUDQPERZCAQ-UHFFFAOYSA-N	276238	5-Methyl-2-[[1-(5-methyl-3-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 176::US10233173, Example 176	Retinoic acid receptor RXR-alpha	Homo sapiens		 929					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276238&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309517	378157908							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524546	Cc1cnc(OCc2cn(nn2)-c2ccnc(Br)c2)nc1	InChI=1S/C13H11BrN6O/c1-9-5-16-13(17-6-9)21-8-10-7-20(19-18-10)11-2-3-15-12(14)4-11/h2-7H,8H2,1H3	KCKZNNXAHNZDOI-UHFFFAOYSA-N	276239	2-[[1-(2-Bromo-4-pyridyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 177::US10233173, Example 177	Retinoic acid receptor RXR-alpha	Homo sapiens		 172					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276239&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309518	378157909							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524547	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C2CCC2)nc1	InChI=1S/C20H22FN5O2/c1-20(2,27)14-9-22-19(23-10-14)28-12-15-11-26(25-24-15)16-6-7-18(21)17(8-16)13-4-3-5-13/h6-11,13,27H,3-5,12H2,1-2H3	QJMNDECZRDOOMP-UHFFFAOYSA-N	276240	2-[2-[[1-(3-Cyclobutyl-4-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidin-::US10071988, Example 178::US10233173, Example 178	Retinoic acid receptor RXR-alpha	Homo sapiens		 349					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276240&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309519	378157910							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524548	CC(C)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C(C)(C)O)nn1	InChI=1S/C19H22FN5O2/c1-12(2)16-7-15(5-6-17(16)20)25-10-14(23-24-25)11-27-18-21-8-13(9-22-18)19(3,4)26/h5-10,12,26H,11H2,1-4H3	XDOXQXVOQXBFEG-UHFFFAOYSA-N	276241	2-[2-[[1-(4-Fluoro-3-isopropyl-phenyl)triazol-4-yl]methoxy]pyrimidin-::US10071988, Example 179::US10233173, Example 179	Retinoic acid receptor RXR-alpha	Homo sapiens		 29.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276241	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276241&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309520	378157911							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524549	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C2CC2)nc1	InChI=1S/C19H20FN5O2/c1-19(2,26)13-8-21-18(22-9-13)27-11-14-10-25(24-23-14)15-5-6-17(20)16(7-15)12-3-4-12/h5-10,12,26H,3-4,11H2,1-2H3	XXVBRVLCQNNZFT-UHFFFAOYSA-N	276242	2-[2-[[1-(3-Cyclopropyl-4-fluoro-phenyl)triazol-4-::US10071988, Example 180::US10233173, Example 180	Retinoic acid receptor RXR-alpha	Homo sapiens		 133					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276242&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309521	378157912							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524550	Cc1cc(ccc1F)-n1cc(COc2ncc(cn2)C(C)(C)O)nn1	InChI=1S/C17H18FN5O2/c1-11-6-14(4-5-15(11)18)23-9-13(21-22-23)10-25-16-19-7-12(8-20-16)17(2,3)24/h4-9,24H,10H2,1-3H3	XKOGRTBPGSQZKS-UHFFFAOYSA-N	276243	2-[2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 181::US10233173, Example 181	Retinoic acid receptor RXR-alpha	Homo sapiens		 97.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276243&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309522	378157913							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524551	CCc1cc(ccc1F)-n1cc(COc2ncc(cn2)C(C)(C)O)nn1	InChI=1S/C18H20FN5O2/c1-4-12-7-15(5-6-16(12)19)24-10-14(22-23-24)11-26-17-20-8-13(9-21-17)18(2,3)25/h5-10,25H,4,11H2,1-3H3	CEVBVYRUQJAONP-UHFFFAOYSA-N	276244	2-[2-[[1-(3-Ethyl-4-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 182::US10233173, Example 182	Retinoic acid receptor RXR-alpha	Homo sapiens		 27.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276244&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309523	378157914							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524552	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(Br)cn2)nn1	InChI=1S/C15H11BrF3N5O/c1-15(18,19)12-4-11(2-3-13(12)17)24-7-10(22-23-24)8-25-14-20-5-9(16)6-21-14/h2-7H,8H2,1H3	VPSZHXPRFZLWNH-UHFFFAOYSA-N	276245	5-Bromo-2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 183::US10233173, Example 183	Retinoic acid receptor RXR-alpha	Homo sapiens		 9.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276245&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302348	378157915							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524553	Cn1ccc(n1)-c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C19H16F3N7O/c1-19(21,22)15-7-14(3-4-16(15)20)29-10-13(25-27-29)11-30-18-23-8-12(9-24-18)17-5-6-28(2)26-17/h3-10H,11H2,1-2H3	VOUQDSWNFXTCLA-UHFFFAOYSA-N	276246	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-(1-::US10071988, Example 184::US10233173, Example 184	Retinoic acid receptor RXR-alpha	Homo sapiens		 309					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276246&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309524	378157916							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524554	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)-c2cn[nH]c2)nn1	InChI=1S/C18H14F3N7O/c1-18(20,21)15-4-14(2-3-16(15)19)28-9-13(26-27-28)10-29-17-22-5-11(6-23-17)12-7-24-25-8-12/h2-9H,10H2,1H3,(H,24,25)	PMKZADUSIHBBGK-UHFFFAOYSA-N	276247	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 185::US10233173, Example 185	Retinoic acid receptor RXR-alpha	Homo sapiens		 166					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276247&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			136214426	378157917							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524555	CC(F)(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)-c2cn[nH]c2)nn1	InChI=1S/C18H14F3N7O/c1-18(20,21)14-6-13(2-3-15(14)19)28-9-12(26-27-28)10-29-17-22-5-4-16(25-17)11-7-23-24-8-11/h2-9H,10H2,1H3,(H,23,24)	WBUFITGSRVAYRU-UHFFFAOYSA-N	276248	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 186::US10233173, Example 186	Retinoic acid receptor RXR-alpha	Homo sapiens		 1360					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276248&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309525	378157918							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524556	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CCOCC2)nn1	InChI=1S/C19H19F3N6O2/c1-19(21,22)16-8-14(2-3-17(16)20)28-11-13(25-26-28)12-30-18-23-9-15(10-24-18)27-4-6-29-7-5-27/h2-3,8-11H,4-7,12H2,1H3	JKSOZUFDHWAKKQ-UHFFFAOYSA-N	276249	4-(2-((1-(3-(1,1-Difluoroethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 187::US10233173, Example 187	Retinoic acid receptor RXR-alpha	Homo sapiens		 88.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276249&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309526	378157919							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524557	FC(F)c1cc(ccc1N1CCC1)-n1cc(COc2ncccn2)nn1	InChI=1S/C17H16F2N6O/c18-16(19)14-9-13(3-4-15(14)24-7-2-8-24)25-10-12(22-23-25)11-26-17-20-5-1-6-21-17/h1,3-6,9-10,16H,2,7-8,11H2	SGTASUVTHIOLRJ-UHFFFAOYSA-N	276250	2-((1-(4-(Azetidin-1-yl)-3-(difluoromethyl)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 188::US10233173, Example 188	Retinoic acid receptor RXR-alpha	Homo sapiens		 4580					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276250&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302223	378157920							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524558	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2cnc(F)cn2)nn1	InChI=1S/C14H9ClF3N5O2/c15-10-2-1-9(3-11(10)25-14(17)18)23-6-8(21-22-23)7-24-13-5-19-12(16)4-20-13/h1-6,14H,7H2	UAALLWNNDBECKP-UHFFFAOYSA-N	276251	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 189::US10233173, Example 189	Retinoic acid receptor RXR-alpha	Homo sapiens		 1460					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276251&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309527	378157921							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524559	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2nccc(Cl)n2)nn1	InChI=1S/C14H9Cl2F2N5O2/c15-10-2-1-9(5-11(10)25-13(17)18)23-6-8(21-22-23)7-24-14-19-4-3-12(16)20-14/h1-6,13H,7H2	YVOZRAAZBKTCTA-UHFFFAOYSA-N	276252	4-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 190::US10233173, Example 190	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276252&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302422	378157922							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524560	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2nccc(F)n2)nn1	InChI=1S/C14H9ClF3N5O2/c15-10-2-1-9(5-11(10)25-13(17)18)23-6-8(21-22-23)7-24-14-19-4-3-12(16)20-14/h1-6,13H,7H2	DREAGQJUVYPIJQ-UHFFFAOYSA-N	276253	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 191::US10233173, Example 191	Retinoic acid receptor RXR-alpha	Homo sapiens		 23.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276253&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309528	378157923							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524561	FCCOc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C16H13ClF3N5O3/c17-13-2-1-11(5-14(13)28-15(19)20)25-8-10(23-24-25)9-27-16-21-6-12(7-22-16)26-4-3-18/h1-2,5-8,15H,3-4,9H2	DTJFCMYFTQGQAV-UHFFFAOYSA-N	276254	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-(2-::US10071988, Example 192::US10233173, Example 192	Retinoic acid receptor RXR-alpha	Homo sapiens		 30.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276254&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309529	378157924							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524562	COc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OCCF)c2)nc1	InChI=1S/C16H15ClFN5O3/c1-24-13-7-19-16(20-8-13)26-10-11-9-23(22-21-11)12-2-3-14(17)15(6-12)25-5-4-18/h2-3,6-9H,4-5,10H2,1H3	KRIKSHONOSOWPQ-UHFFFAOYSA-N	276255	2-[[1-[4-Chloro-3-(2-fluoroethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 193::US10233173, Example 193	Retinoic acid receptor RXR-alpha	Homo sapiens		 89.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276255&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309530	378157925							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524563	COc1cnc(OCc2cn(nn2)-c2ccc(F)c(CCCF)c2)nc1	InChI=1S/C17H17F2N5O2/c1-25-15-8-20-17(21-9-15)26-11-13-10-24(23-22-13)14-4-5-16(19)12(7-14)3-2-6-18/h4-5,7-10H,2-3,6,11H2,1H3	LIINQGXMCZNARI-UHFFFAOYSA-N	276256	2-[[1-[4-Fluoro-3-(3-fluoropropyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 194::US10233173, Example 194	Retinoic acid receptor RXR-alpha	Homo sapiens		 61.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276256&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302377	378157926							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524564	COc1cnc(OCc2cn(nn2)-c2ccc(F)c(CCCCl)c2)nc1	InChI=1S/C17H17ClFN5O2/c1-25-15-8-20-17(21-9-15)26-11-13-10-24(23-22-13)14-4-5-16(19)12(7-14)3-2-6-18/h4-5,7-10H,2-3,6,11H2,1H3	LGCJDGRREPFXRR-UHFFFAOYSA-N	276257	2-[[1-[3-(3-Chloropropyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 195::US10233173, Example 195	Retinoic acid receptor RXR-alpha	Homo sapiens		 136					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276257&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309532	378157927							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524565	FCCCc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C17H15ClF3N5O2/c18-14-4-3-13(6-15(14)28-16(20)21)26-9-12(24-25-26)10-27-17-22-7-11(8-23-17)2-1-5-19/h3-4,6-9,16H,1-2,5,10H2	XGCIWNYJAXZXRA-UHFFFAOYSA-N	276258	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-(3-::US10071988, Example 196::US10233173, Example 196	Retinoic acid receptor RXR-alpha	Homo sapiens		 24.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276258&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309531	378157928							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524566	FC(F)c1cccc(c1)-n1cc(CNc2ncc(F)cn2)nn1	InChI=1S/C14H11F3N6/c15-10-5-18-14(19-6-10)20-7-11-8-23(22-21-11)12-3-1-2-9(4-12)13(16)17/h1-6,8,13H,7H2,(H,18,19,20)	KBILNAFSJPAOBT-UHFFFAOYSA-N	276259	N-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methyl]-5-fluoro-::US10071988, Example 197::US10233173, Example 197	Retinoic acid receptor RXR-alpha	Homo sapiens		 652					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276259&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309533	378157929							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524567	Cc1cnc(NCc2cn(nn2)-c2ccc(F)c(C)c2)nc1	InChI=1S/C15H15FN6/c1-10-6-17-15(18-7-10)19-8-12-9-22(21-20-12)13-3-4-14(16)11(2)5-13/h3-7,9H,8H2,1-2H3,(H,17,18,19)	VVWHCBBEOHFJDR-UHFFFAOYSA-N	276260	N-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methyl]-5-methyl-::US10071988, Example 198::US10233173, Example 198	Retinoic acid receptor RXR-alpha	Homo sapiens		 147					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276260&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309534	378157930							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524568	Cc1cc(ccc1F)-n1cc(CNc2ncc(Cl)c(C)n2)nn1	InChI=1S/C15H14ClFN6/c1-9-5-12(3-4-14(9)17)23-8-11(21-22-23)6-18-15-19-7-13(16)10(2)20-15/h3-5,7-8H,6H2,1-2H3,(H,18,19,20)	YTJNAGGBOKRPLD-UHFFFAOYSA-N	276261	5-Chloro-N-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-yl]methyl]-4-::US10071988, Example 199::US10233173, Example 199	Retinoic acid receptor RXR-alpha	Homo sapiens		 51.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276261&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309535	378157931							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524569	FC(F)c1cc(ccc1Cl)-n1cc(CNc2ncc(Cl)cn2)nn1	InChI=1S/C14H10Cl2F2N6/c15-8-4-19-14(20-5-8)21-6-9-7-24(23-22-9)10-1-2-12(16)11(3-10)13(17)18/h1-5,7,13H,6H2,(H,19,20,21)	QLUSCZBXOHDFFF-UHFFFAOYSA-N	276262	5-Chloro-N-[[1-[4-chloro-3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 200::US10233173, Example 200	Retinoic acid receptor RXR-alpha	Homo sapiens		 131					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276262&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309536	378157932							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524570	Cc1ccnc(NCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C15H13ClF2N6/c1-9-4-5-19-15(21-9)20-7-10-8-24(23-22-10)11-2-3-13(16)12(6-11)14(17)18/h2-6,8,14H,7H2,1H3,(H,19,20,21)	RILPHJXAIBWSTR-UHFFFAOYSA-N	276263	N-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methyl]-4-::US10071988, Example 201::US10233173, Example 201	Retinoic acid receptor RXR-alpha	Homo sapiens		 100.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276263&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309537	378157933							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524571	CCc1cnc(NCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C16H15ClF2N6/c1-2-10-6-20-16(21-7-10)22-8-11-9-25(24-23-11)12-3-4-14(17)13(5-12)15(18)19/h3-7,9,15H,2,8H2,1H3,(H,20,21,22)	SLWPORQAZPQGGV-UHFFFAOYSA-N	276264	N-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methyl]-5-::US10071988, Example 202::US10233173, Example 202	Retinoic acid receptor RXR-alpha	Homo sapiens		 44.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276264&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309538	378157934							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524572	COc1cnc(NCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C15H13ClF2N6O/c1-25-11-6-20-15(21-7-11)19-5-9-8-24(23-22-9)10-2-3-13(16)12(4-10)14(17)18/h2-4,6-8,14H,5H2,1H3,(H,19,20,21)	IUTOHTCSZQLSEN-UHFFFAOYSA-N	276265	N-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methyl]-5-::US10071988, Example 203::US10233173, Example 203	Retinoic acid receptor RXR-alpha	Homo sapiens		 30.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276265&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309541	378157935							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524573	FC(F)c1cnc(NCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C15H11ClF4N6/c16-12-2-1-10(3-11(12)14(19)20)26-7-9(24-25-26)6-23-15-21-4-8(5-22-15)13(17)18/h1-5,7,13-14H,6H2,(H,21,22,23)	VLJOAPRBHFSYSI-UHFFFAOYSA-N	276266	N-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methyl]-5-::US10071988, Example 204::US10233173, Example 204	Retinoic acid receptor RXR-alpha	Homo sapiens		 240					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276266&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309539	378157936							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524574	FC(F)c1cc(ccc1Cl)-n1cc(CNc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H10ClF5N6/c16-12-2-1-10(3-11(12)13(17)18)27-7-9(25-26-27)6-24-14-22-4-8(5-23-14)15(19,20)21/h1-5,7,13H,6H2,(H,22,23,24)	RBMLVDDPQOSFNC-UHFFFAOYSA-N	276267	N-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methyl]-5-::US10071988, Example 205::US10233173, Example 205	Retinoic acid receptor RXR-alpha	Homo sapiens		 616					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276267&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309540	378157937							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524575	Cc1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C16H15F3N6/c1-10-6-20-15(21-7-10)22-8-11-9-25(24-23-11)12-3-4-14(17)13(5-12)16(2,18)19/h3-7,9H,8H2,1-2H3,(H,20,21,22)	ZGHAHXVYJIGRQG-UHFFFAOYSA-N	276268	N-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 206::US10233173, Example 206	Retinoic acid receptor RXR-alpha	Homo sapiens		 219					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276268&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309542	378157938							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524576	CCc1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C17H17F3N6/c1-3-11-7-21-16(22-8-11)23-9-12-10-26(25-24-12)13-4-5-15(18)14(6-13)17(2,19)20/h4-8,10H,3,9H2,1-2H3,(H,21,22,23)	STMQASJBRQCPLG-UHFFFAOYSA-N	276269	N-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 207::US10233173, Example 207	Retinoic acid receptor RXR-alpha	Homo sapiens		 128					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276269&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309546	378157939							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524577	CC(C)c1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C18H19F3N6/c1-11(2)12-7-22-17(23-8-12)24-9-13-10-27(26-25-13)14-4-5-16(19)15(6-14)18(3,20)21/h4-8,10-11H,9H2,1-3H3,(H,22,23,24)	UMXMMJFTIVEJIB-UHFFFAOYSA-N	276270	N-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 208::US10233173, Example 208	Retinoic acid receptor RXR-alpha	Homo sapiens		 581					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276270&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309543	378157940							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524578	CC(F)(F)c1cc(ccc1F)-n1cc(CNc2ncc(cn2)C2CC2)nn1	InChI=1S/C18H17F3N6/c1-18(20,21)15-6-14(4-5-16(15)19)27-10-13(25-26-27)9-24-17-22-7-12(8-23-17)11-2-3-11/h4-8,10-11H,2-3,9H2,1H3,(H,22,23,24)	XKBLAHHUONCUSU-UHFFFAOYSA-N	276271	5-Cyclopropyl-N-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]triazol-::US10071988, Example 209::US10233173, Example 209	Retinoic acid receptor RXR-alpha	Homo sapiens		 104					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276271&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309547	378157941							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524579	Cc1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1C	InChI=1S/C17H17F3N6/c1-10-7-21-16(23-11(10)2)22-8-12-9-26(25-24-12)13-4-5-15(18)14(6-13)17(3,19)20/h4-7,9H,8H2,1-3H3,(H,21,22,23)	NOAKWUGKJARXNN-UHFFFAOYSA-N	276272	N-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-::US10071988, Example 210::US10233173, Example 210	Retinoic acid receptor RXR-alpha	Homo sapiens		 50.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276272&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309544	378157942							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524580	Cc1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C15H13F3N6/c1-9-5-19-15(20-6-9)21-7-10-8-24(23-22-10)11-2-3-13(16)12(4-11)14(17)18/h2-6,8,14H,7H2,1H3,(H,19,20,21)	FILPSSROSVJMRN-UHFFFAOYSA-N	276273	N-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-5-::US10071988, Example 211::US10233173, Example 211	Retinoic acid receptor RXR-alpha	Homo sapiens		 49.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276273&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309545	378157943							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524581	FC(F)c1cc(ccc1F)-n1cc(CNc2ncc(Cl)cn2)nn1	InChI=1S/C14H10ClF3N6/c15-8-4-19-14(20-5-8)21-6-9-7-24(23-22-9)10-1-2-12(16)11(3-10)13(17)18/h1-5,7,13H,6H2,(H,19,20,21)	MDSVIRSWONSGIY-UHFFFAOYSA-N	276274	5-Chloro-N-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 212::US10233173, Example 212	Retinoic acid receptor RXR-alpha	Homo sapiens		 74.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276274&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309548	378157944							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524582	FC(F)c1cc(ccc1F)-n1cc(CNc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H10F6N6/c16-12-2-1-10(3-11(12)13(17)18)27-7-9(25-26-27)6-24-14-22-4-8(5-23-14)15(19,20)21/h1-5,7,13H,6H2,(H,22,23,24)	RCXGWIVBAFMDDU-UHFFFAOYSA-N	276275	N-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methyl]-5-::US10071988, Example 213::US10233173, Example 213	Retinoic acid receptor RXR-alpha	Homo sapiens		 108					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276275&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309549	378157945							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524583	CC(C)(O)c1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C17H17F3N6O/c1-17(2,27)10-6-21-16(22-7-10)23-8-11-9-26(25-24-11)12-3-4-14(18)13(5-12)15(19)20/h3-7,9,15,27H,8H2,1-2H3,(H,21,22,23)	LKQMBFKPHZCOPA-UHFFFAOYSA-N	276276	2-[2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 214::US10233173, Example 214	Retinoic acid receptor RXR-alpha	Homo sapiens		 654					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276276&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309550	378157946							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524584	FC(F)c1cc(ccc1F)-n1cc(CNc2ccccn2)nn1	InChI=1S/C15H12F3N5/c16-13-5-4-11(7-12(13)15(17)18)23-9-10(21-22-23)8-20-14-3-1-2-6-19-14/h1-7,9,15H,8H2,(H,19,20)	YGHDLFYHNBXYQI-UHFFFAOYSA-N	276277	N-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 215::US10233173, Example 215	Retinoic acid receptor RXR-alpha	Homo sapiens		 986					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276277&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302291	378157947							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524585	CCc1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C16H15F3N6/c1-2-10-6-20-16(21-7-10)22-8-11-9-25(24-23-11)12-3-4-14(17)13(5-12)15(18)19/h3-7,9,15H,2,8H2,1H3,(H,20,21,22)	SOSUBIQNRCZYSX-UHFFFAOYSA-N	276278	N-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 216::US10233173, Example 216	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276278&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302292	378157948							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524586	Cc1cnc(NCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1C	InChI=1S/C16H15F3N6/c1-9-6-20-16(22-10(9)2)21-7-11-8-25(24-23-11)12-3-4-14(17)13(5-12)15(18)19/h3-6,8,15H,7H2,1-2H3,(H,20,21,22)	PVTAARQHRNZNHU-UHFFFAOYSA-N	276279	N-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 217::US10233173, Example 217	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276279&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302180	378157949							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524587	Cc1nc(NCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)ncc1Cl	InChI=1S/C15H12ClF3N6/c1-8-12(16)6-21-15(22-8)20-5-9-7-25(24-23-9)10-2-3-13(17)11(4-10)14(18)19/h2-4,6-7,14H,5H2,1H3,(H,20,21,22)	JYKHQMNSOQIWJH-UHFFFAOYSA-N	276280	5-Chloro-N-((1-(3-(difluoromethyl)-4-fluorophenyl)-1H-1,2,3-::US10071988, Example 218::US10233173, Example 218	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276280&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302366	378157950							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524588	Cn1nccc1NCc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C14H13F3N6/c1-22-13(4-5-19-22)18-7-9-8-23(21-20-9)10-2-3-12(15)11(6-10)14(16)17/h2-6,8,14,18H,7H2,1H3	FVIVYBGLEXVIDT-UHFFFAOYSA-N	276281	N-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 219::US10233173, Example 219	Retinoic acid receptor RXR-alpha	Homo sapiens		>10000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276281&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302249	378157951							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524589	Cn1ccnc1NCc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C14H13F3N6/c1-22-5-4-18-14(22)19-7-9-8-23(21-20-9)10-2-3-12(15)11(6-10)13(16)17/h2-6,8,13H,7H2,1H3,(H,18,19)	AIKWHCGPYMZUGV-UHFFFAOYSA-N	276282	N-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 220::US10233173, Example 220	Retinoic acid receptor RXR-alpha	Homo sapiens		 3650					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276282&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302231	378157952							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524590	FC(F)Oc1cc(ccc1F)-n1cc(CNc2ccccn2)nn1	InChI=1S/C15H12F3N5O/c16-12-5-4-11(7-13(12)24-15(17)18)23-9-10(21-22-23)8-20-14-3-1-2-6-19-14/h1-7,9,15H,8H2,(H,19,20)	JXNHBWJWUKGKKX-UHFFFAOYSA-N	276283	N-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 221::US10233173, Example 221	Retinoic acid receptor RXR-alpha	Homo sapiens		 724					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276283&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302282	378157953							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524591	Cc1cnc(NCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)nc1	InChI=1S/C15H13F3N6O/c1-9-5-19-15(20-6-9)21-7-10-8-24(23-22-10)11-2-3-12(16)13(4-11)25-14(17)18/h2-6,8,14H,7H2,1H3,(H,19,20,21)	HYIUNWASQYVMMA-UHFFFAOYSA-N	276284	N-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 222::US10233173, Example 222	Retinoic acid receptor RXR-alpha	Homo sapiens		 64.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276284&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302240	378157954							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524592	Cn1nccc1NCc1cn(nn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C14H13F3N6O/c1-22-13(4-5-19-22)18-7-9-8-23(21-20-9)10-2-3-11(15)12(6-10)24-14(16)17/h2-6,8,14,18H,7H2,1H3	USNCSLUFDQPMLJ-UHFFFAOYSA-N	276285	N-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 223::US10233173, Example 223	Retinoic acid receptor RXR-alpha	Homo sapiens		 11801					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276285&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302229	378157955							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524593	C[C@@H](Nc1ncc(C)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H15ClF2N6O/c1-9-6-20-16(21-7-9)22-10(2)13-8-25(24-23-13)11-3-4-12(17)14(5-11)26-15(18)19/h3-8,10,15H,1-2H3,(H,20,21,22)/t10-/m1/s1	UKSZEYYGKNMYHW-SNVBAGLBSA-N	276286	N-[(1R)-1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 224::US10233173, Example 224	Retinoic acid receptor RXR-alpha	Homo sapiens		 121					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276286&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302238	378157956							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524594	Clc1ccc(cc1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C13H9Cl2N5O/c14-9-1-3-12(4-2-9)20-7-11(18-19-20)8-21-13-16-5-10(15)6-17-13/h1-7H,8H2	WPPCVYINGVMQSJ-UHFFFAOYSA-N	276287	5-Chloro-2-[[1-(4-chlorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 225::US10233173, Example 225	Retinoic acid receptor RXR-alpha	Homo sapiens		 70.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276287&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309552	378157957							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524595	FC(F)(F)c1cnc(OCc2cn(nn2)-c2ccc(Cl)cc2)nc1	InChI=1S/C14H9ClF3N5O/c15-10-1-3-12(4-2-10)23-7-11(21-22-23)8-24-13-19-5-9(6-20-13)14(16,17)18/h1-7H,8H2	CNBNXYLIYHUXTQ-UHFFFAOYSA-N	276288	2-[[1-(4-Chlorophenyl)triazol-4-yl]methoxy]-5-::US10071988, Example 226::US10233173, Example 226	Retinoic acid receptor RXR-alpha	Homo sapiens		 155					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276288&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309551	378157958							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524596	FC(F)Oc1cnc(OCc2cn(nn2)-c2ccc(Cl)cc2)nc1	InChI=1S/C14H10ClF2N5O2/c15-9-1-3-11(4-2-9)22-7-10(20-21-22)8-23-14-18-5-12(6-19-14)24-13(16)17/h1-7,13H,8H2	AYQMQCZQHUXIQA-UHFFFAOYSA-N	276289	2-[[1-(4-Chlorophenyl)triazol-4-yl]methoxy]-5-::US10071988, Example 227::US10233173, Example 227	Retinoic acid receptor RXR-alpha	Homo sapiens		 151					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276289&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309555	378157959							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524597	Fc1cccc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C13H10FN5O/c14-10-3-1-4-12(7-10)19-8-11(17-18-19)9-20-13-15-5-2-6-16-13/h1-8H,9H2	XNROXRCXABFYRV-UHFFFAOYSA-N	276290	2-[[1-(3-Fluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 228::US10233173, Example 228	Retinoic acid receptor RXR-alpha	Homo sapiens		 5649					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276290&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309553	378157960							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524598	Fc1cccc(c1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C13H9F2N5O/c14-9-2-1-3-12(4-9)20-7-11(18-19-20)8-21-13-16-5-10(15)6-17-13/h1-7H,8H2	IPUCKYRNTOYDCT-UHFFFAOYSA-N	276291	5-Fluoro-2-[[1-(3-fluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 229::US10233173, Example 229	Retinoic acid receptor RXR-alpha	Homo sapiens		 2980					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276291&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309554	378157961							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524599	COc1cnc(OCc2cn(nn2)-c2cccc(F)c2)nc1	InChI=1S/C14H12FN5O2/c1-21-13-6-16-14(17-7-13)22-9-11-8-20(19-18-11)12-4-2-3-10(15)5-12/h2-8H,9H2,1H3	CAOPKQLXSVOJOM-UHFFFAOYSA-N	276292	2-[[1-(3-Fluorophenyl)triazol-4-yl]methoxy]-5-methoxy-pyrimidine;::US10071988, Example 230::US10233173, Example 230	Retinoic acid receptor RXR-alpha	Homo sapiens		 275					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276292&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309556	378157962							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524600	Fc1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C13H9ClFN5O/c14-9-5-16-13(17-6-9)21-8-11-7-20(19-18-11)12-3-1-2-10(15)4-12/h1-7H,8H2	GRXRBVBTZBFVMO-UHFFFAOYSA-N	276293	5-Chloro-2-[[1-(3-fluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 231::US10233173, Example 231	Retinoic acid receptor RXR-alpha	Homo sapiens		 389					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276293&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309557	378157963							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524601	Cc1cnc(OCc2cn(nn2)-c2cccc(F)c2)nc1	InChI=1S/C14H12FN5O/c1-10-6-16-14(17-7-10)21-9-12-8-20(19-18-12)13-4-2-3-11(15)5-13/h2-8H,9H2,1H3	LDKJXVWCHRTAEI-UHFFFAOYSA-N	276294	2-[[1-(3-Fluorophenyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 232::US10233173, Example 232	Retinoic acid receptor RXR-alpha	Homo sapiens		 205					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276294&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309558	378157964							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524602	CCc1cnc(OCc2cn(nn2)-c2cccc(F)c2)nc1	InChI=1S/C15H14FN5O/c1-2-11-7-17-15(18-8-11)22-10-13-9-21(20-19-13)14-5-3-4-12(16)6-14/h3-9H,2,10H2,1H3	CDLGLJPFWLZOIF-UHFFFAOYSA-N	276295	5-Ethyl-2-[[1-(3-fluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 233::US10233173, Example 233	Retinoic acid receptor RXR-alpha	Homo sapiens		 75.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276295&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309559	378157965							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524603	Cc1cnc(OCc2cn(nn2)-c2cccc(Br)c2)nc1	InChI=1S/C14H12BrN5O/c1-10-6-16-14(17-7-10)21-9-12-8-20(19-18-12)13-4-2-3-11(15)5-13/h2-8H,9H2,1H3	LTQTZHVGIAPGCH-UHFFFAOYSA-N	276296	2-[[1-(3-Bromophenyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 234::US10233173, Example 234	Retinoic acid receptor RXR-alpha	Homo sapiens		 22.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276296&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309560	378157966							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524604	Cc1ccccc1-n1cc(COc2ncccn2)nn1	InChI=1S/C14H13N5O/c1-11-5-2-3-6-13(11)19-9-12(17-18-19)10-20-14-15-7-4-8-16-14/h2-9H,10H2,1H3	NNOWAFPLAULLTC-UHFFFAOYSA-N	276297	2-[[1-(o-Tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 236::US10233173, Example 236	Retinoic acid receptor RXR-alpha	Homo sapiens		>10000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276297&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309562	378157967							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524605	Cc1ccccc1-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H12FN5O/c1-10-4-2-3-5-13(10)20-8-12(18-19-20)9-21-14-16-6-11(15)7-17-14/h2-8H,9H2,1H3	WSDPXHAZJVKRQS-UHFFFAOYSA-N	276298	5-Fluoro-2-[[1-(o-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 237::US10233173, Example 237	Retinoic acid receptor RXR-alpha	Homo sapiens		 16600					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276298&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309563	378157968							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524606	COc1cnc(OCc2cn(nn2)-c2ccccc2C)nc1	InChI=1S/C15H15N5O2/c1-11-5-3-4-6-14(11)20-9-12(18-19-20)10-22-15-16-7-13(21-2)8-17-15/h3-9H,10H2,1-2H3	ZISPPSOZRRNLHH-UHFFFAOYSA-N	276299	5-Methoxy-2-[[1-(o-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 238::US10233173, Example 238	Retinoic acid receptor RXR-alpha	Homo sapiens		 5990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276299&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309564	378157969							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524607	Cc1ccccc1-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H12ClN5O/c1-10-4-2-3-5-13(10)20-8-12(18-19-20)9-21-14-16-6-11(15)7-17-14/h2-8H,9H2,1H3	QPEUTXKTHCYSOS-UHFFFAOYSA-N	276300	5-Chloro-2-[[1-(o-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 239::US10233173, Example 239	Retinoic acid receptor RXR-alpha	Homo sapiens		 4800					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276300&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309565	378157970							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524608	Cc1cnc(OCc2cn(nn2)-c2ccccc2C)nc1	InChI=1S/C15H15N5O/c1-11-7-16-15(17-8-11)21-10-13-9-20(19-18-13)14-6-4-3-5-12(14)2/h3-9H,10H2,1-2H3	GVELSBJMXNSIJS-UHFFFAOYSA-N	276301	5-Methyl-2-[[1-(o-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 240::US10233173, Example 240	Retinoic acid receptor RXR-alpha	Homo sapiens		 5580					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276301&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309570	378157971							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524609	CCc1cnc(OCc2cn(nn2)-c2ccccc2C)nc1	InChI=1S/C16H17N5O/c1-3-13-8-17-16(18-9-13)22-11-14-10-21(20-19-14)15-7-5-4-6-12(15)2/h4-10H,3,11H2,1-2H3	VGDSMHSRUOBBGT-UHFFFAOYSA-N	276302	5-Ethyl-2-[[1-(o-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 241::US10233173, Example 241	Retinoic acid receptor RXR-alpha	Homo sapiens		 1460					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276302&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309566	378157972							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524610	Cc1cccc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H13N5O/c1-11-4-2-5-13(8-11)19-9-12(17-18-19)10-20-14-15-6-3-7-16-14/h2-9H,10H2,1H3	FTCWBGAWOPRVIR-UHFFFAOYSA-N	276303	2-[[1-(m-Tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 242::US10233173, Example 242	Retinoic acid receptor RXR-alpha	Homo sapiens		 647					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276303&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309567	378157973							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524611	Cc1cccc(c1)-n1cc(COc2ncc(C)cn2)nn1	InChI=1S/C15H15N5O/c1-11-4-3-5-14(6-11)20-9-13(18-19-20)10-21-15-16-7-12(2)8-17-15/h3-9H,10H2,1-2H3	SBVYALDFQLTXPI-UHFFFAOYSA-N	276304	5-Methyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 243::US10233173, Example 243	Retinoic acid receptor RXR-alpha	Homo sapiens		 14.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276304&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309568	378157974							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524612	Cc1cccc(c1)-n1cc(COc2nccc(C)n2)nn1	InChI=1S/C15H15N5O/c1-11-4-3-5-14(8-11)20-9-13(18-19-20)10-21-15-16-7-6-12(2)17-15/h3-9H,10H2,1-2H3	XIXYJRWFWDHDCL-UHFFFAOYSA-N	276305	4-Methyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 244::US10233173, Example 244	Retinoic acid receptor RXR-alpha	Homo sapiens		 191					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276305&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309569	378157975							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524613	CCc1cnc(OCc2cn(nn2)-c2cccc(C)c2)nc1	InChI=1S/C16H17N5O/c1-3-13-8-17-16(18-9-13)22-11-14-10-21(20-19-14)15-6-4-5-12(2)7-15/h4-10H,3,11H2,1-2H3	CILBJZDUPAQVPL-UHFFFAOYSA-N	276306	5-Ethyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 245::US10233173, Example 245	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276306&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309571	378157976							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524614	Cc1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H12ClN5O/c1-10-3-2-4-13(5-10)20-8-12(18-19-20)9-21-14-16-6-11(15)7-17-14/h2-8H,9H2,1H3	FMYAQBNTFWSMBU-UHFFFAOYSA-N	276307	5-Chloro-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 246::US10233173, Example 246	Retinoic acid receptor RXR-alpha	Homo sapiens		 33.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276307&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309572	378157977							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524615	Cc1cccc(c1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H12FN5O/c1-10-3-2-4-13(5-10)20-8-12(18-19-20)9-21-14-16-6-11(15)7-17-14/h2-8H,9H2,1H3	FUVDIQNVUXWXTJ-UHFFFAOYSA-N	276308	5-Fluoro-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 247::US10233173, Example 247	Retinoic acid receptor RXR-alpha	Homo sapiens		 340					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276308&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309573	378157978							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524616	COc1cnc(OCc2cn(nn2)-c2cccc(C)c2)nc1	InChI=1S/C15H15N5O2/c1-11-4-3-5-13(6-11)20-9-12(18-19-20)10-22-15-16-7-14(21-2)8-17-15/h3-9H,10H2,1-2H3	RIHMLUZYRKTLCI-UHFFFAOYSA-N	276309	5-Methoxy-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 248::US10233173, Example 248	Retinoic acid receptor RXR-alpha	Homo sapiens		 9.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276309&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309574	378157979							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524617	Cc1cccc(c1)-n1cc(COc2ncc(cn2)C(C)(C)O)nn1	InChI=1S/C17H19N5O2/c1-12-5-4-6-15(7-12)22-10-14(20-21-22)11-24-16-18-8-13(9-19-16)17(2,3)23/h4-10,23H,11H2,1-3H3	ZLVNBTGXIWXXHJ-UHFFFAOYSA-N	276310	2-[2-[[1-(m-Tolyl)triazol-4-yl]methoxy]pyrimidin-5-yl]propan-2-ol;::US10071988, Example 249::US10233173, Example 249	Retinoic acid receptor RXR-alpha	Homo sapiens		 289					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276310&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309580	378157980							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524618	COCc1ccnc(OCc2cn(nn2)-c2cccc(C)c2)n1	InChI=1S/C16H17N5O2/c1-12-4-3-5-15(8-12)21-9-14(19-20-21)11-23-16-17-7-6-13(18-16)10-22-2/h3-9H,10-11H2,1-2H3	KATMYSMPNNJVMF-UHFFFAOYSA-N	276311	4-(Methoxymethyl)-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 250::US10233173, Example 250	Retinoic acid receptor RXR-alpha	Homo sapiens		 249					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276311&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309575	378157981							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524619	Cc1cccc(c1)-n1cc(COc2ncc(C)c(C)n2)nn1	InChI=1S/C16H17N5O/c1-11-5-4-6-15(7-11)21-9-14(19-20-21)10-22-16-17-8-12(2)13(3)18-16/h4-9H,10H2,1-3H3	ZGYQZWNAZQMRTL-UHFFFAOYSA-N	276312	4,5-Dimethyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 251::US10233173, Example 251	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276312&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309583	378157982							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524620	Cc1cccc(c1)-n1cc(COc2ncc(F)c(C)n2)nn1	InChI=1S/C15H14FN5O/c1-10-4-3-5-13(6-10)21-8-12(19-20-21)9-22-15-17-7-14(16)11(2)18-15/h3-8H,9H2,1-2H3	MCXUMRUDJKRBJG-UHFFFAOYSA-N	276313	5-Fluoro-4-methyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 252::US10233173, Example 252	Retinoic acid receptor RXR-alpha	Homo sapiens		 65.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276313&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309584	378157983							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524621	Cc1cccc(c1)-n1cc(COc2ncc(Cl)c(C)n2)nn1	InChI=1S/C15H14ClN5O/c1-10-4-3-5-13(6-10)21-8-12(19-20-21)9-22-15-17-7-14(16)11(2)18-15/h3-8H,9H2,1-2H3	NAJHBWATMIGXHO-UHFFFAOYSA-N	276314	5-Chloro-4-methyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 253::US10233173, Example 253	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276314&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309578	378157984							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524622	Cc1cccc(c1)-n1cc(COc2ncc(C)c(N)n2)nn1	InChI=1S/C15H16N6O/c1-10-4-3-5-13(6-10)21-8-12(19-20-21)9-22-15-17-7-11(2)14(16)18-15/h3-8H,9H2,1-2H3,(H2,16,17,18)	RAAFFIJKIWTACE-UHFFFAOYSA-N	276315	5-Methyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]pyrimidin-4-amine;::US10071988, Example 254::US10233173, Example 254	Retinoic acid receptor RXR-alpha	Homo sapiens		 151					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276315&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309585	378157985							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524623	CC(=O)c1cnc(OCc2cn(nn2)-c2cccc(C)c2)nc1	InChI=1S/C16H15N5O2/c1-11-4-3-5-15(6-11)21-9-14(19-20-21)10-23-16-17-7-13(8-18-16)12(2)22/h3-9H,10H2,1-2H3	OQYBBRMGLVKPKU-UHFFFAOYSA-N	276316	1-[2-[[1-(m-Tolyl)triazol-4-yl]methoxy]pyrimidin-5-yl]ethanone;::US10071988, Example 255::US10233173, Example 255	Retinoic acid receptor RXR-alpha	Homo sapiens		 224					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276316&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309576	378157986							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524624	Cc1ccc(cc1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H13N5O/c1-11-3-5-13(6-4-11)19-9-12(17-18-19)10-20-14-15-7-2-8-16-14/h2-9H,10H2,1H3	PUUYKJFMDYPTTA-UHFFFAOYSA-N	276317	2-[[1-(p-Tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 256::US10233173, Example 256	Retinoic acid receptor RXR-alpha	Homo sapiens		 4420					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276317&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309586	378157987							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524625	Cc1ccc(cc1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H12FN5O/c1-10-2-4-13(5-3-10)20-8-12(18-19-20)9-21-14-16-6-11(15)7-17-14/h2-8H,9H2,1H3	CNLTXPWDBYGADP-UHFFFAOYSA-N	276318	5-Fluoro-2-[[1-(p-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 257::US10233173, Example 257	Retinoic acid receptor RXR-alpha	Homo sapiens		 2690					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276318&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309577	378157988							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524626	COc1cnc(OCc2cn(nn2)-c2ccc(C)cc2)nc1	InChI=1S/C15H15N5O2/c1-11-3-5-13(6-4-11)20-9-12(18-19-20)10-22-15-16-7-14(21-2)8-17-15/h3-9H,10H2,1-2H3	XGQRPXPEPYHSLG-UHFFFAOYSA-N	276319	5-Methoxy-2-[[1-(p-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 258::US10233173, Example 258	Retinoic acid receptor RXR-alpha	Homo sapiens		 225					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276319&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309579	378157989							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524627	Cc1ccc(cc1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H12ClN5O/c1-10-2-4-13(5-3-10)20-8-12(18-19-20)9-21-14-16-6-11(15)7-17-14/h2-8H,9H2,1H3	KBXHAJBKOZAYID-UHFFFAOYSA-N	276320	5-Chloro-2-[[1-(p-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 259::US10233173, Example 259	Retinoic acid receptor RXR-alpha	Homo sapiens		 711					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276320	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276320&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309581	378157990							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524628	Cc1ccc(cc1)-n1cc(COc2ncc(C)cn2)nn1	InChI=1S/C15H15N5O/c1-11-3-5-14(6-4-11)20-9-13(18-19-20)10-21-15-16-7-12(2)8-17-15/h3-9H,10H2,1-2H3	DQDVGOXHXUCPCO-UHFFFAOYSA-N	276321	5-Methyl-2-[[1-(p-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 260::US10233173, Example 260	Retinoic acid receptor RXR-alpha	Homo sapiens		 271					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276321&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309582	378157991							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524629	CCc1cnc(OCc2cn(nn2)-c2ccc(C)cc2)nc1	InChI=1S/C16H17N5O/c1-3-13-8-17-16(18-9-13)22-11-14-10-21(20-19-14)15-6-4-12(2)5-7-15/h4-10H,3,11H2,1-2H3	FDPCUBPNONXGBX-UHFFFAOYSA-N	276322	5-Ethyl-2-[[1-(p-tolyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 261::US10233173, Example 261	Retinoic acid receptor RXR-alpha	Homo sapiens		 93.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276322&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309590	378157992							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524630	CC(C)c1cccc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C16H17N5O/c1-12(2)13-5-3-6-15(9-13)21-10-14(19-20-21)11-22-16-17-7-4-8-18-16/h3-10,12H,11H2,1-2H3	VBTLXHBZYARDPV-UHFFFAOYSA-N	276323	2-[[1-(3-Isopropylphenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 262::US10233173, Example 262	Retinoic acid receptor RXR-alpha	Homo sapiens		 358					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276323&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302288	378157993							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524631	CC(C)c1cccc(c1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C16H16FN5O/c1-11(2)12-4-3-5-15(6-12)22-9-14(20-21-22)10-23-16-18-7-13(17)8-19-16/h3-9,11H,10H2,1-2H3	NQZRWLMACPRZGB-UHFFFAOYSA-N	276324	5-Fluoro-2-[[1-(3-isopropylphenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 263::US10233173, Example 263	Retinoic acid receptor RXR-alpha	Homo sapiens		 227					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276324&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309593	378157994							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524632	COc1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)C)nc1	InChI=1S/C17H19N5O2/c1-12(2)13-5-4-6-15(7-13)22-10-14(20-21-22)11-24-17-18-8-16(23-3)9-19-17/h4-10,12H,11H2,1-3H3	YUZFVMBPSSOBRT-UHFFFAOYSA-N	276325	2-[[1-(3-Isopropylphenyl)triazol-4-yl]methoxy]-5-methoxy-pyrimidine;::US10071988, Example 264::US10233173, Example 264	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276325&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302343	378157995							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524633	CC(C)c1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C16H16ClN5O/c1-11(2)12-4-3-5-15(6-12)22-9-14(20-21-22)10-23-16-18-7-13(17)8-19-16/h3-9,11H,10H2,1-2H3	ZRPHYVGZHMEBMW-UHFFFAOYSA-N	276326	5-Chloro-2-[[1-(3-isopropylphenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 265::US10233173, Example 265	Retinoic acid receptor RXR-alpha	Homo sapiens		 16.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276326&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309591	378157996							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524634	CC(C)c1cccc(c1)-n1cc(COc2ncc(C)cn2)nn1	InChI=1S/C17H19N5O/c1-12(2)14-5-4-6-16(7-14)22-10-15(20-21-22)11-23-17-18-8-13(3)9-19-17/h4-10,12H,11H2,1-3H3	KIWXREINVNXDAY-UHFFFAOYSA-N	276327	2-[[1-(3-Isopropylphenyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 266::US10233173, Example 266	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276327&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302443	378157997							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524635	CCc1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)C)nc1	InChI=1S/C18H21N5O/c1-4-14-9-19-18(20-10-14)24-12-16-11-23(22-21-16)17-7-5-6-15(8-17)13(2)3/h5-11,13H,4,12H2,1-3H3	PDIXWPZDTATARG-UHFFFAOYSA-N	276328	5-Ethyl-2-[[1-(3-isopropylphenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 267::US10233173, Example 267	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276328&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309587	378157998							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524636	Cc1ccnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)n1	InChI=1S/C15H13F2N5O/c1-10-5-6-18-15(19-10)23-9-12-8-22(21-20-12)13-4-2-3-11(7-13)14(16)17/h2-8,14H,9H2,1H3	GMCMFSDACWJXKY-UHFFFAOYSA-N	276329	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-methyl-::US10071988, Example 268::US10233173, Example 268	Retinoic acid receptor RXR-alpha	Homo sapiens		 134					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276329&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309594	378157999							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524637	FC(F)c1cccc(c1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H10F3N5O/c15-10-5-18-14(19-6-10)23-8-11-7-22(21-20-11)12-3-1-2-9(4-12)13(16)17/h1-7,13H,8H2	OAKOVYAJQBUXNK-UHFFFAOYSA-N	276330	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-fluoro-::US10071988, Example 269::US10233173, Example 269	Retinoic acid receptor RXR-alpha	Homo sapiens		 325					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276330&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309588	378158000							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524638	CC(C)c1ccnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)n1	InChI=1S/C17H17F2N5O/c1-11(2)15-6-7-20-17(21-15)25-10-13-9-24(23-22-13)14-5-3-4-12(8-14)16(18)19/h3-9,11,16H,10H2,1-2H3	OYVRSUCRABSCJZ-UHFFFAOYSA-N	276331	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-isopropyl-::US10071988, Example 270::US10233173, Example 270	Retinoic acid receptor RXR-alpha	Homo sapiens		 617					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276331&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309589	378158001							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524639	COCc1ccnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)n1	InChI=1S/C16H15F2N5O2/c1-24-9-12-5-6-19-16(20-12)25-10-13-8-23(22-21-13)14-4-2-3-11(7-14)15(17)18/h2-8,15H,9-10H2,1H3	YJHNSEKRIYSGCL-UHFFFAOYSA-N	276332	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 271::US10233173, Example 271	Retinoic acid receptor RXR-alpha	Homo sapiens		 360					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276332&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309596	378158002							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524640	CC(C)(O)c1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1	InChI=1S/C17H17F2N5O2/c1-17(2,25)12-7-20-16(21-8-12)26-10-13-9-24(23-22-13)14-5-3-4-11(6-14)15(18)19/h3-9,15,25H,10H2,1-2H3	PUDAQFHBSVHSQX-UHFFFAOYSA-N	276333	2-[2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 272::US10233173, Example 272	Retinoic acid receptor RXR-alpha	Homo sapiens		 173					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276333&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309592	378158003							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524641	FC(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C(F)F)nn1	InChI=1S/C15H11F4N5O/c16-13(17)9-2-1-3-12(4-9)24-7-11(22-23-24)8-25-15-20-5-10(6-21-15)14(18)19/h1-7,13-14H,8H2	FWWLFKCNPNILNR-UHFFFAOYSA-N	276334	5-(Difluoromethyl)-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 273::US10233173, Example 273	Retinoic acid receptor RXR-alpha	Homo sapiens		 27.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276334&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309595	378158004							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524642	FC(F)c1cccc(c1)-n1cc(COc2nccc(n2)C(F)F)nn1	InChI=1S/C15H11F4N5O/c16-13(17)9-2-1-3-11(6-9)24-7-10(22-23-24)8-25-15-20-5-4-12(21-15)14(18)19/h1-7,13-14H,8H2	AQENRZZXNBCFLE-UHFFFAOYSA-N	276335	4-(Difluoromethyl)-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 274::US10233173, Example 274	Retinoic acid receptor RXR-alpha	Homo sapiens		 813					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276335&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309598	378158005							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524643	FC(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H10F5N5O/c16-13(17)9-2-1-3-12(4-9)25-7-11(23-24-25)8-26-14-21-5-10(6-22-14)15(18,19)20/h1-7,13H,8H2	HXWFXQBXTRMISY-UHFFFAOYSA-N	276336	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 275::US10233173, Example 275	Retinoic acid receptor RXR-alpha	Homo sapiens		 25.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276336&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309597	378158006							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524644	FC(F)Oc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)nc1	InChI=1S/C15H11F4N5O2/c16-13(17)9-2-1-3-11(4-9)24-7-10(22-23-24)8-25-15-20-5-12(6-21-15)26-14(18)19/h1-7,13-14H,8H2	IIIXWSDMSFNCGD-UHFFFAOYSA-N	276337	5-(Difluoromethoxy)-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 276::US10233173, Example 276	Retinoic acid receptor RXR-alpha	Homo sapiens		 31.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276337&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309599	378158007							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524645	CN(C)c1ccnc(OCc2cn(nn2)-c2cccc(c2)C(F)F)n1	InChI=1S/C16H16F2N6O/c1-23(2)14-6-7-19-16(20-14)25-10-12-9-24(22-21-12)13-5-3-4-11(8-13)15(17)18/h3-9,15H,10H2,1-2H3	VVESMMQELUCHPM-UHFFFAOYSA-N	276338	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-N,N-dimethyl-::US10071988, Example 277::US10233173, Example 277	Retinoic acid receptor RXR-alpha	Homo sapiens		 41.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276338&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309600	378158008							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524646	Cc1nc(OCc2cn(nn2)-c2cccc(c2)C(F)F)ncc1F	InChI=1S/C15H12F3N5O/c1-9-13(16)6-19-15(20-9)24-8-11-7-23(22-21-11)12-4-2-3-10(5-12)14(17)18/h2-7,14H,8H2,1H3	QZYQWQZBZLPROU-UHFFFAOYSA-N	276339	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-fluoro-4-::US10071988, Example 278::US10233173, Example 278	Retinoic acid receptor RXR-alpha	Homo sapiens		 42.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276339&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309601	378158009							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524647	Cc1nc(OCc2cn(nn2)-c2cccc(c2)C(F)F)ncc1Cl	InChI=1S/C15H12ClF2N5O/c1-9-13(16)6-19-15(20-9)24-8-11-7-23(22-21-11)12-4-2-3-10(5-12)14(17)18/h2-7,14H,8H2,1H3	CSNKNUVEKTZXOA-UHFFFAOYSA-N	276340	5-Chloro-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 279::US10233173, Example 279	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276340&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309602	378158010							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524648	Cc1cnc(Cl)nc1OCc1cn(nn1)-c1cccc(c1)C(F)F	InChI=1S/C15H12ClF2N5O/c1-9-6-19-15(16)20-14(9)24-8-11-7-23(22-21-11)12-4-2-3-10(5-12)13(17)18/h2-7,13H,8H2,1H3	RXGCTQNFLADCMA-UHFFFAOYSA-N	276341	2-Chloro-4-[[1-[3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 280::US10233173, Example 280	Retinoic acid receptor RXR-alpha	Homo sapiens		 173					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276341&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309603	378158011							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524649	CN(C)c1nc(OCc2cn(nn2)-c2cccc(c2)C(F)F)ncc1C	InChI=1S/C17H18F2N6O/c1-11-8-20-17(21-16(11)24(2)3)26-10-13-9-25(23-22-13)14-6-4-5-12(7-14)15(18)19/h4-9,15H,10H2,1-3H3	GESLBJPYIKHTEE-UHFFFAOYSA-N	276342	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-N,N,5-trimethyl-::US10071988, Example 281::US10233173, Example 281	Retinoic acid receptor RXR-alpha	Homo sapiens		 130					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276342&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309604	378158012							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524650	FC(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C17H15F2N5O/c18-16(19)12-2-1-3-15(6-12)24-9-14(22-23-24)10-25-17-20-7-13(8-21-17)11-4-5-11/h1-3,6-9,11,16H,4-5,10H2	UFSFZUOWIFWKPX-UHFFFAOYSA-N	276343	5-Cyclopropyl-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 282::US10233173, Example 282	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276343&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309605	378158013							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524651	FC(F)c1cccc(c1)-n1cc(COc2nccc(n2)C2CC2)nn1	InChI=1S/C17H15F2N5O/c18-16(19)12-2-1-3-14(8-12)24-9-13(22-23-24)10-25-17-20-7-6-15(21-17)11-4-5-11/h1-3,6-9,11,16H,4-5,10H2	VOTVYVWYBAXYPS-UHFFFAOYSA-N	276344	4-Cyclopropyl-2-[[1-[3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 283::US10233173, Example 283	Retinoic acid receptor RXR-alpha	Homo sapiens		 169					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276344&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309608	378158014							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524652	FC(F)c1cccc(c1)-n1cc(COc2nccc(n2)N2CCCC2)nn1	InChI=1S/C18H18F2N6O/c19-17(20)13-4-3-5-15(10-13)26-11-14(23-24-26)12-27-18-21-7-6-16(22-18)25-8-1-2-9-25/h3-7,10-11,17H,1-2,8-9,12H2	XLVTWBNFTRXBOG-UHFFFAOYSA-N	276345	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-pyrrolidin-1-::US10071988, Example 284::US10233173, Example 284	Retinoic acid receptor RXR-alpha	Homo sapiens		 94.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276345&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309606	378158015							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524653	FC(F)c1cccc(c1)-n1cc(COc2nccc(n2)N2CCCCC2)nn1	InChI=1S/C19H20F2N6O/c20-18(21)14-5-4-6-16(11-14)27-12-15(24-25-27)13-28-19-22-8-7-17(23-19)26-9-2-1-3-10-26/h4-8,11-12,18H,1-3,9-10,13H2	AXGSFWZEJWEDFN-UHFFFAOYSA-N	276346	2-[[1-[3-(Difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-(1-::US10071988, Example 285::US10233173, Example 285	Retinoic acid receptor RXR-alpha	Homo sapiens		 299					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276346&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309607	378158016							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524654	Cc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)(F)F)nc1	InChI=1S/C15H12F3N5O/c1-10-6-19-14(20-7-10)24-9-12-8-23(22-21-12)13-4-2-3-11(5-13)15(16,17)18/h2-8H,9H2,1H3	ZZBLYUQWLMSBSL-UHFFFAOYSA-N	276347	5-Methyl-2-[[1-[3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 286::US10233173, Example 286	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276347&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309609	378158017							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524655	CCc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)(F)F)nc1	InChI=1S/C16H14F3N5O/c1-2-11-7-20-15(21-8-11)25-10-13-9-24(23-22-13)14-5-3-4-12(6-14)16(17,18)19/h3-9H,2,10H2,1H3	DUMWUIUZPQQFQP-UHFFFAOYSA-N	276348	5-Ethyl-2-[[1-[3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 287::US10233173, Example 287	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276348&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309610	378158018							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524656	CC(C)c1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)(F)F)nc1	InChI=1S/C17H16F3N5O/c1-11(2)12-7-21-16(22-8-12)26-10-14-9-25(24-23-14)15-5-3-4-13(6-15)17(18,19)20/h3-9,11H,10H2,1-2H3	JRWIPGDXKDTDTQ-UHFFFAOYSA-N	276349	5-Isopropyl-2-[[1-[3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 288::US10233173, Example 288	Retinoic acid receptor RXR-alpha	Homo sapiens		 40.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276349&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309611	378158019							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524657	FC(F)c1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)(F)F)nc1	InChI=1S/C15H10F5N5O/c16-13(17)9-5-21-14(22-6-9)26-8-11-7-25(24-23-11)12-3-1-2-10(4-12)15(18,19)20/h1-7,13H,8H2	LEGUCUZQIORZIX-UHFFFAOYSA-N	276350	5-(Difluoromethyl)-2-[[1-[3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 289::US10233173, Example 289	Retinoic acid receptor RXR-alpha	Homo sapiens		 37.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276350&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309615	378158020							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524658	Cc1cnc(OCc2cn(nn2)-c2cccc(c2)C(F)(F)F)nc1C	InChI=1S/C16H14F3N5O/c1-10-7-20-15(21-11(10)2)25-9-13-8-24(23-22-13)14-5-3-4-12(6-14)16(17,18)19/h3-8H,9H2,1-2H3	OWLVCEBXNIZAQX-UHFFFAOYSA-N	276351	4,5-Dimethyl-2-[[1-[3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 290::US10233173, Example 290	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276351&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309612	378158021							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524659	Cc1nc(OCc2cn(nn2)-c2cccc(c2)C(F)(F)F)ncc1Cl	InChI=1S/C15H11ClF3N5O/c1-9-13(16)6-20-14(21-9)25-8-11-7-24(23-22-11)12-4-2-3-10(5-12)15(17,18)19/h2-7H,8H2,1H3	RDMKPFWOCGXQED-UHFFFAOYSA-N	276352	5-Chloro-4-methyl-2-[[1-[3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 291::US10233173, Example 291	Retinoic acid receptor RXR-alpha	Homo sapiens		 9.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276352&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309613	378158022							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524660	CC(F)(F)c1cccc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C15H13F2N5O/c1-15(16,17)11-4-2-5-13(8-11)22-9-12(20-21-22)10-23-14-18-6-3-7-19-14/h2-9H,10H2,1H3	LUMPNOFZUWQEKZ-UHFFFAOYSA-N	276353	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 292::US10233173, Example 292	Retinoic acid receptor RXR-alpha	Homo sapiens		 105					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276353&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309614	378158023							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524661	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(Br)cn2)nn1	InChI=1S/C15H12BrF2N5O/c1-15(17,18)10-3-2-4-13(5-10)23-8-12(21-22-23)9-24-14-19-6-11(16)7-20-14/h2-8H,9H2,1H3	ACMVJUFVEAPEFM-UHFFFAOYSA-N	276354	5-Bromo-2-[[1-[3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 293::US10233173, Example 293	Retinoic acid receptor RXR-alpha	Homo sapiens		 39.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276354&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302432	378158024							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524662	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C15H12ClF2N5O/c1-15(17,18)10-3-2-4-13(5-10)23-8-12(21-22-23)9-24-14-19-6-11(16)7-20-14/h2-8H,9H2,1H3	SAYVLXHJEFSMFG-UHFFFAOYSA-N	276355	5-Chloro-2-[[1-[3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 294::US10233173, Example 294	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276355&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302436	378158025							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524663	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C15H12F3N5O/c1-15(17,18)10-3-2-4-13(5-10)23-8-12(21-22-23)9-24-14-19-6-11(16)7-20-14/h2-8H,9H2,1H3	PTYPUEKMLNVOIR-UHFFFAOYSA-N	276356	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-fluoro-::US10071988, Example 295::US10233173, Example 295	Retinoic acid receptor RXR-alpha	Homo sapiens		 61.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276356&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309620	378158026							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524664	Cc1ccnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)n1	InChI=1S/C16H15F2N5O/c1-11-6-7-19-15(20-11)24-10-13-9-23(22-21-13)14-5-3-4-12(8-14)16(2,17)18/h3-9H,10H2,1-2H3	LFYHAOBDKUNQCP-UHFFFAOYSA-N	276357	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-methyl-::US10071988, Example 296::US10233173, Example 296	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276357&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309616	378158027							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524665	Cc1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)nc1	InChI=1S/C16H15F2N5O/c1-11-7-19-15(20-8-11)24-10-13-9-23(22-21-13)14-5-3-4-12(6-14)16(2,17)18/h3-9H,10H2,1-2H3	QJKSTFMELSVAJZ-UHFFFAOYSA-N	276358	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 297::US10233173, Example 297	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276358&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309621	378158028							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524666	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(CO)cn2)nn1	InChI=1S/C16H15F2N5O2/c1-16(17,18)12-3-2-4-14(5-12)23-8-13(21-22-23)10-25-15-19-6-11(9-24)7-20-15/h2-8,24H,9-10H2,1H3	ATGKEIPRIZGCLE-UHFFFAOYSA-N	276359	US10071988, Example 298::US10233173, Example 298::[2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-5-	Retinoic acid receptor RXR-alpha	Homo sapiens		 34.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276359&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309617	378158029							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524667	CC(F)(F)c1cccc(c1)-n1cc(COc2nccc(CO)n2)nn1	InChI=1S/C16H15F2N5O2/c1-16(17,18)11-3-2-4-14(7-11)23-8-13(21-22-23)10-25-15-19-6-5-12(9-24)20-15/h2-8,24H,9-10H2,1H3	QWDWGFRYIGOUMN-UHFFFAOYSA-N	276360	US10071988, Example 299::US10233173, Example 299::[2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 49.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276360&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309618	378158030							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524668	COCc1ccnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)n1	InChI=1S/C17H17F2N5O2/c1-17(18,19)12-4-3-5-15(8-12)24-9-14(22-23-24)11-26-16-20-7-6-13(21-16)10-25-2/h3-9H,10-11H2,1-2H3	SCRBAEHBXBDYJQ-UHFFFAOYSA-N	276361	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 300::US10233173, Example 300	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276361&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309619	378158031							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524669	CC(C)(O)c1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)nc1	InChI=1S/C18H19F2N5O2/c1-17(2,26)13-8-21-16(22-9-13)27-11-14-10-25(24-23-14)15-6-4-5-12(7-15)18(3,19)20/h4-10,26H,11H2,1-3H3	XGXFNQVBFLEUDV-UHFFFAOYSA-N	276362	2-[2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 301::US10233173, Example 301	Retinoic acid receptor RXR-alpha	Homo sapiens		 119					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276362&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309622	378158032							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524670	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C(F)F)nn1	InChI=1S/C16H13F4N5O/c1-16(19,20)11-3-2-4-13(5-11)25-8-12(23-24-25)9-26-15-21-6-10(7-22-15)14(17)18/h2-8,14H,9H2,1H3	UYFCKWPCNYULBG-UHFFFAOYSA-N	276363	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 302::US10233173, Example 302	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276363&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309623	378158033							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524671	CC(F)(F)c1cccc(c1)-n1cc(COc2nccc(n2)C(F)F)nn1	InChI=1S/C16H13F4N5O/c1-16(19,20)10-3-2-4-12(7-10)25-8-11(23-24-25)9-26-15-21-6-5-13(22-15)14(17)18/h2-8,14H,9H2,1H3	PTBQKLCWWXSEIV-UHFFFAOYSA-N	276364	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 303::US10233173, Example 303	Retinoic acid receptor RXR-alpha	Homo sapiens		 85.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276364&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309624	378158034							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524672	CC(F)(F)c1cccc(c1)-n1cc(COc2nccc(n2)C(F)(F)F)nn1	InChI=1S/C16H12F5N5O/c1-15(17,18)10-3-2-4-12(7-10)26-8-11(24-25-26)9-27-14-22-6-5-13(23-14)16(19,20)21/h2-8H,9H2,1H3	IEHKMOHHWZPHQN-UHFFFAOYSA-N	276365	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 304::US10233173, Example 304	Retinoic acid receptor RXR-alpha	Homo sapiens		 711					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276365&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309627	378158035							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524673	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C(C)(O)C(F)(F)F)nn1	InChI=1S/C18H16F5N5O2/c1-16(29,18(21,22)23)12-7-24-15(25-8-12)30-10-13-9-28(27-26-13)14-5-3-4-11(6-14)17(2,19)20/h3-9,29H,10H2,1-2H3	MHTZIZIGETWUOY-UHFFFAOYSA-N	276366	(R/S)-2-[2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-::US10071988, Example 305::US10233173, Example 305	Retinoic acid receptor RXR-alpha	Homo sapiens		 496					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276366&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309625	378158036							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524674	COc1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)nc1	InChI=1S/C16H15F2N5O2/c1-16(17,18)11-4-3-5-13(6-11)23-9-12(21-22-23)10-25-15-19-7-14(24-2)8-20-15/h3-9H,10H2,1-2H3	KVWSKYUCWYUREB-UHFFFAOYSA-N	276367	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 306::US10233173, Example 306	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276367&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309626	378158037							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524675	COc1ccnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)n1	InChI=1S/C16H15F2N5O2/c1-16(17,18)11-4-3-5-13(8-11)23-9-12(21-22-23)10-25-15-19-7-6-14(20-15)24-2/h3-9H,10H2,1-2H3	QWBDJIXFGDXIAT-UHFFFAOYSA-N	276368	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-methoxy-::US10071988, Example 307::US10233173, Example 307	Retinoic acid receptor RXR-alpha	Homo sapiens		 33.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276368	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276368&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309628	378158038							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524676	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(OC(F)F)cn2)nn1	InChI=1S/C16H13F4N5O2/c1-16(19,20)10-3-2-4-12(5-10)25-8-11(23-24-25)9-26-15-21-6-13(7-22-15)27-14(17)18/h2-8,14H,9H2,1H3	SLQBVFLRMZIFQM-UHFFFAOYSA-N	276369	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 308::US10233173, Example 308	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276369&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309632	378158039							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524677	CC(=O)c1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)nc1	InChI=1S/C17H15F2N5O2/c1-11(25)12-7-20-16(21-8-12)26-10-14-9-24(23-22-14)15-5-3-4-13(6-15)17(2,18)19/h3-9H,10H2,1-2H3	CCRKAPILJDMYFZ-UHFFFAOYSA-N	276370	1-[2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 309::US10233173, Example 309	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276370&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309629	378158040							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524678	CC(O)c1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)nc1	InChI=1S/C17H17F2N5O2/c1-11(25)12-7-20-16(21-8-12)26-10-14-9-24(23-22-14)15-5-3-4-13(6-15)17(2,18)19/h3-9,11,25H,10H2,1-2H3	RJPYSHYKKCASOB-UHFFFAOYSA-N	276371	(R/S)-1-[2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-::US10071988, Example 310::US10233173, Example 310	Retinoic acid receptor RXR-alpha	Homo sapiens		 37.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276371&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309630	378158041							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524679	COC(C)c1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)nc1	InChI=1S/C18H19F2N5O2/c1-12(26-3)13-8-21-17(22-9-13)27-11-15-10-25(24-23-15)16-6-4-5-14(7-16)18(2,19)20/h4-10,12H,11H2,1-3H3	UUDYMHAKLMETEX-UHFFFAOYSA-N	276372	(R/S)-2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-(1-::US10071988, Example 311::US10233173, Example 311	Retinoic acid receptor RXR-alpha	Homo sapiens		 1580					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276372&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309631	378158042							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524680	Cc1nc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)ncc1Cl	InChI=1S/C16H14ClF2N5O/c1-10-14(17)7-20-15(21-10)25-9-12-8-24(23-22-12)13-5-3-4-11(6-13)16(2,18)19/h3-8H,9H2,1-2H3	FCUVSEDUXSZNKT-UHFFFAOYSA-N	276373	5-Chloro-2-[[1-[3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 312::US10233173, Example 312	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276373&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309633	378158043							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524681	Cc1nc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)ncc1F	InChI=1S/C16H14F3N5O/c1-10-14(17)7-20-15(21-10)25-9-12-8-24(23-22-12)13-5-3-4-11(6-13)16(2,18)19/h3-8H,9H2,1-2H3	PTWWLTPIWDJSOM-UHFFFAOYSA-N	276374	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-fluoro-4-::US10071988, Example 313::US10233173, Example 313	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276374&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309634	378158044							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524682	Cc1cnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)nc1N	InChI=1S/C16H16F2N6O/c1-10-7-20-15(21-14(10)19)25-9-12-8-24(23-22-12)13-5-3-4-11(6-13)16(2,17)18/h3-8H,9H2,1-2H3,(H2,19,20,21)	PJCLLNSBIIKCKI-UHFFFAOYSA-N	276375	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 314::US10233173, Example 314	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276375&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309635	378158045							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524683	CNc1nc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)ncc1F	InChI=1S/C16H15F3N6O/c1-16(18,19)10-4-3-5-12(6-10)25-8-11(23-24-25)9-26-15-21-7-13(17)14(20-2)22-15/h3-8H,9H2,1-2H3,(H,20,21,22)	MLIPEULGBRJHDW-UHFFFAOYSA-N	276376	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-fluoro-N-::US10071988, Example 315::US10233173, Example 315	Retinoic acid receptor RXR-alpha	Homo sapiens		 158					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276376&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309636	378158046							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524684	CC(F)(F)c1cccc(c1)-n1cc(COc2nccc(N)n2)nn1	InChI=1S/C15H14F2N6O/c1-15(16,17)10-3-2-4-12(7-10)23-8-11(21-22-23)9-24-14-19-6-5-13(18)20-14/h2-8H,9H2,1H3,(H2,18,19,20)	XFGNMUNIQKIGIJ-UHFFFAOYSA-N	276377	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]pyrimidin-4-::US10071988, Example 316::US10233173, Example 316	Retinoic acid receptor RXR-alpha	Homo sapiens		 183					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276377&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309637	378158047							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524685	CNc1ccnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)n1	InChI=1S/C16H16F2N6O/c1-16(17,18)11-4-3-5-13(8-11)24-9-12(22-23-24)10-25-15-20-7-6-14(19-2)21-15/h3-9H,10H2,1-2H3,(H,19,20,21)	SPEQASRRMWSMMT-UHFFFAOYSA-N	276378	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-N-methyl-::US10071988, Example 317::US10233173, Example 317	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276378&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309638	378158048							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524686	CN(C)c1ccnc(OCc2cn(nn2)-c2cccc(c2)C(C)(F)F)n1	InChI=1S/C17H18F2N6O/c1-17(18,19)12-5-4-6-14(9-12)25-10-13(22-23-25)11-26-16-20-8-7-15(21-16)24(2)3/h4-10H,11H2,1-3H3	UKWUAWKCSVJIOD-UHFFFAOYSA-N	276379	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-N,N-dimethyl-::US10071988, Example 318::US10233173, Example 318	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276379&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309639	378158049							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524687	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C18H17F2N5O/c1-18(19,20)14-3-2-4-16(7-14)25-10-15(23-24-25)11-26-17-21-8-13(9-22-17)12-5-6-12/h2-4,7-10,12H,5-6,11H2,1H3	ZZPOEZQWQQSOPW-UHFFFAOYSA-N	276380	5-Cyclopropyl-2-[[1-[3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 319::US10233173, Example 319	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276380&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309640	378158050							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524688	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(cn2)N2CCC2)nn1	InChI=1S/C18H18F2N6O/c1-18(19,20)13-4-2-5-15(8-13)26-11-14(23-24-26)12-27-17-21-9-16(10-22-17)25-6-3-7-25/h2,4-5,8-11H,3,6-7,12H2,1H3	YDTFEIGBNSZMCI-UHFFFAOYSA-N	276381	5-(Azetidin-1-yl)-2-[[1-[3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 320::US10233173, Example 320	Retinoic acid receptor RXR-alpha	Homo sapiens		 61.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276381&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302203	378158051							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524689	CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(cn2)N2CC(F)C2)nn1	InChI=1S/C18H17F3N6O/c1-18(20,21)12-3-2-4-15(5-12)27-10-14(24-25-27)11-28-17-22-6-16(7-23-17)26-8-13(19)9-26/h2-7,10,13H,8-9,11H2,1H3	DLGHJAVDNMGGST-UHFFFAOYSA-N	276382	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-(3-::US10071988, Example 321::US10233173, Example 321	Retinoic acid receptor RXR-alpha	Homo sapiens		 104					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276382&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309641	378158052							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524690	CC(F)(F)c1cccc(c1)-n1cc(COc2nccc(n2)N2CCCC2)nn1	InChI=1S/C19H20F2N6O/c1-19(20,21)14-5-4-6-16(11-14)27-12-15(24-25-27)13-28-18-22-8-7-17(23-18)26-9-2-3-10-26/h4-8,11-12H,2-3,9-10,13H2,1H3	PEJYCAVTIOKBOF-UHFFFAOYSA-N	276383	2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-pyrrolidin-1-::US10071988, Example 322::US10233173, Example 322	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276383&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309642	378158053							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524691	FC(F)Oc1cccc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H11F2N5O2/c15-13(16)23-12-4-1-3-11(7-12)21-8-10(19-20-21)9-22-14-17-5-2-6-18-14/h1-8,13H,9H2	JEJWZFXCYJKDPA-UHFFFAOYSA-N	276384	2-[[1-[3-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 323::US10233173, Example 323	Retinoic acid receptor RXR-alpha	Homo sapiens		 788					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276384&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309643	378158054							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524692	FC(F)Oc1cccc(c1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H10F3N5O2/c15-9-5-18-14(19-6-9)23-8-10-7-22(21-20-10)11-2-1-3-12(4-11)24-13(16)17/h1-7,13H,8H2	NTGYEDFWTKMVLR-UHFFFAOYSA-N	276385	2-[[1-[3-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-fluoro-::US10071988, Example 324::US10233173, Example 324	Retinoic acid receptor RXR-alpha	Homo sapiens		 494					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276385&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309644	378158055							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524693	COc1cnc(OCc2cn(nn2)-c2cccc(OC(F)F)c2)nc1	InChI=1S/C15H13F2N5O3/c1-23-13-6-18-15(19-7-13)24-9-10-8-22(21-20-10)11-3-2-4-12(5-11)25-14(16)17/h2-8,14H,9H2,1H3	JWBLOPVZWHLMIE-UHFFFAOYSA-N	276386	2-[[1-[3-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 325::US10233173, Example 325	Retinoic acid receptor RXR-alpha	Homo sapiens		 27.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276386&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309645	378158056							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524694	FC(F)Oc1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H10ClF2N5O2/c15-9-5-18-14(19-6-9)23-8-10-7-22(21-20-10)11-2-1-3-12(4-11)24-13(16)17/h1-7,13H,8H2	FBWOKJSKMPHWLA-UHFFFAOYSA-N	276387	5-Chloro-2-[[1-[3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 326::US10233173, Example 326	Retinoic acid receptor RXR-alpha	Homo sapiens		 69.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276387&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309656	378158057							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524695	Cc1cnc(OCc2cn(nn2)-c2cccc(OC(F)F)c2)nc1	InChI=1S/C15H13F2N5O2/c1-10-6-18-15(19-7-10)23-9-11-8-22(21-20-11)12-3-2-4-13(5-12)24-14(16)17/h2-8,14H,9H2,1H3	QMYPDBMXMVHSTP-UHFFFAOYSA-N	276388	2-[[1-[3-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 327::US10233173, Example 327	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276388&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309646	378158058							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524696	CCc1cnc(OCc2cn(nn2)-c2cccc(OC(F)F)c2)nc1	InChI=1S/C16H15F2N5O2/c1-2-11-7-19-16(20-8-11)24-10-12-9-23(22-21-12)13-4-3-5-14(6-13)25-15(17)18/h3-9,15H,2,10H2,1H3	AGUAHSXVFZGKSM-UHFFFAOYSA-N	276389	2-[[1-[3-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-ethyl-::US10071988, Example 328::US10233173, Example 328	Retinoic acid receptor RXR-alpha	Homo sapiens		 29.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276389&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309648	378158059							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524697	FC(F)Oc1ccc(cc1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H11F2N5O2/c15-13(16)23-12-4-2-11(3-5-12)21-8-10(19-20-21)9-22-14-17-6-1-7-18-14/h1-8,13H,9H2	ALGPUCKEMSZLCV-UHFFFAOYSA-N	276390	2-[[1-[4-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 329::US10233173, Example 329	Retinoic acid receptor RXR-alpha	Homo sapiens		 854					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276390&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309647	378158060							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524698	FC(F)Oc1ccc(cc1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H10F3N5O2/c15-9-5-18-14(19-6-9)23-8-10-7-22(21-20-10)11-1-3-12(4-2-11)24-13(16)17/h1-7,13H,8H2	DLVRVIOUMSQWGU-UHFFFAOYSA-N	276391	2-[[1-[4-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-fluoro-::US10071988, Example 330::US10233173, Example 330	Retinoic acid receptor RXR-alpha	Homo sapiens		 752					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276391&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309649	378158061							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524699	COc1cnc(OCc2cn(nn2)-c2ccc(OC(F)F)cc2)nc1	InChI=1S/C15H13F2N5O3/c1-23-13-6-18-15(19-7-13)24-9-10-8-22(21-20-10)11-2-4-12(5-3-11)25-14(16)17/h2-8,14H,9H2,1H3	NEKJPVPOTZZPTB-UHFFFAOYSA-N	276392	2-[[1-[4-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 331::US10233173, Example 331	Retinoic acid receptor RXR-alpha	Homo sapiens		 98.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276392&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309650	378158062							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524700	FC(F)Oc1ccc(cc1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H10ClF2N5O2/c15-9-5-18-14(19-6-9)23-8-10-7-22(21-20-10)11-1-3-12(4-2-11)24-13(16)17/h1-7,13H,8H2	CYBOKVJLDTXKCJ-UHFFFAOYSA-N	276393	5-Chloro-2-[[1-[4-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 332::US10233173, Example 332	Retinoic acid receptor RXR-alpha	Homo sapiens		 200					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276393&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309662	378158063							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524701	Cc1cnc(OCc2cn(nn2)-c2ccc(OC(F)F)cc2)nc1	InChI=1S/C15H13F2N5O2/c1-10-6-18-15(19-7-10)23-9-11-8-22(21-20-11)12-2-4-13(5-3-12)24-14(16)17/h2-8,14H,9H2,1H3	NWSUJKDVPQIUTL-UHFFFAOYSA-N	276394	2-[[1-[4-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 333::US10233173, Example 333	Retinoic acid receptor RXR-alpha	Homo sapiens		 87.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276394&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309668	378158064							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524702	CCc1cnc(OCc2cn(nn2)-c2ccc(OC(F)F)cc2)nc1	InChI=1S/C16H15F2N5O2/c1-2-11-7-19-16(20-8-11)24-10-12-9-23(22-21-12)13-3-5-14(6-4-13)25-15(17)18/h3-9,15H,2,10H2,1H3	HDCYXKUEVKNLSP-UHFFFAOYSA-N	276395	2-[[1-[4-(Difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-ethyl-::US10071988, Example 334::US10233173, Example 334	Retinoic acid receptor RXR-alpha	Homo sapiens		 51.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276395&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309653	378158065							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524703	FC(F)(F)Oc1ccc(cc1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H10F3N5O2/c15-14(16,17)24-12-4-2-11(3-5-12)22-8-10(20-21-22)9-23-13-18-6-1-7-19-13/h1-8H,9H2	DDSYTEDPBGFVKU-UHFFFAOYSA-N	276396	2-[[1-[4-(Trifluoromethoxy)phenyl]triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 335::US10233173, Example 335	Retinoic acid receptor RXR-alpha	Homo sapiens		 3120					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276396&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309663	378158066							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524704	Fc1cnc(OCc2cn(nn2)-c2ccc(OC(F)(F)F)cc2)nc1	InChI=1S/C14H9F4N5O2/c15-9-5-19-13(20-6-9)24-8-10-7-23(22-21-10)11-1-3-12(4-2-11)25-14(16,17)18/h1-7H,8H2	NAMSJKUCJUFXAG-UHFFFAOYSA-N	276397	5-Fluoro-2-[[1-[4-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 336::US10233173, Example 336	Retinoic acid receptor RXR-alpha	Homo sapiens		 11301					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276397&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309651	378158067							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524705	COc1cnc(OCc2cn(nn2)-c2ccc(OC(F)(F)F)cc2)nc1	InChI=1S/C15H12F3N5O3/c1-24-13-6-19-14(20-7-13)25-9-10-8-23(22-21-10)11-2-4-12(5-3-11)26-15(16,17)18/h2-8H,9H2,1H3	SFMYDYOFALQBDP-UHFFFAOYSA-N	276398	5-Methoxy-2-[[1-[4-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 337::US10233173, Example 337	Retinoic acid receptor RXR-alpha	Homo sapiens		>10000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276398&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309658	378158068							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524706	FC(F)(F)Oc1ccc(cc1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H9ClF3N5O2/c15-9-5-19-13(20-6-9)24-8-10-7-23(22-21-10)11-1-3-12(4-2-11)25-14(16,17)18/h1-7H,8H2	ULCWYBVKKSMNHB-UHFFFAOYSA-N	276399	5-Chloro-2-[[1-[4-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 338::US10233173, Example 338	Retinoic acid receptor RXR-alpha	Homo sapiens		 9049					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276399&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309654	378158069							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524707	Cc1cnc(OCc2cn(nn2)-c2ccc(OC(F)(F)F)cc2)nc1	InChI=1S/C15H12F3N5O2/c1-10-6-19-14(20-7-10)24-9-11-8-23(22-21-11)12-2-4-13(5-3-12)25-15(16,17)18/h2-8H,9H2,1H3	KDUBLSVWXLTSTB-UHFFFAOYSA-N	276400	5-Methyl-2-[[1-[4-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 339::US10233173, Example 339	Retinoic acid receptor RXR-alpha	Homo sapiens		 1130					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276400&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309652	378158070							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524708	CCc1cnc(OCc2cn(nn2)-c2ccc(OC(F)(F)F)cc2)nc1	InChI=1S/C16H14F3N5O2/c1-2-11-7-20-15(21-8-11)25-10-12-9-24(23-22-12)13-3-5-14(6-4-13)26-16(17,18)19/h3-9H,2,10H2,1H3	ZBUGBEZMMWBEIH-UHFFFAOYSA-N	276401	5-Ethyl-2-[[1-[4-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 340::US10233173, Example 340	Retinoic acid receptor RXR-alpha	Homo sapiens		 794					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276401&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309660	378158071							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524709	FC(F)(F)Oc1cccc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H10F3N5O2/c15-14(16,17)24-12-4-1-3-11(7-12)22-8-10(20-21-22)9-23-13-18-5-2-6-19-13/h1-8H,9H2	FUVDMSLFXZZADE-UHFFFAOYSA-N	276402	2-[[1-[3-(Trifluoromethoxy)phenyl]triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 341::US10233173, Example 341	Retinoic acid receptor RXR-alpha	Homo sapiens		 538					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276402&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309655	378158072							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524710	Cc1cnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)nc1	InChI=1S/C15H12F3N5O2/c1-10-6-19-14(20-7-10)24-9-11-8-23(22-21-11)12-3-2-4-13(5-12)25-15(16,17)18/h2-8H,9H2,1H3	DXKWZUXEJKLYQU-UHFFFAOYSA-N	276403	5-Methyl-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 342::US10233173, Example 342	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276403&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309657	378158073							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524711	Cc1cnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)nc1N	InChI=1S/C15H13F3N6O2/c1-9-6-20-14(21-13(9)19)25-8-10-7-24(23-22-10)11-3-2-4-12(5-11)26-15(16,17)18/h2-7H,8H2,1H3,(H2,19,20,21)	VMNZGYVAICSFKF-UHFFFAOYSA-N	276404	5-Methyl-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 343::US10233173, Example 343	Retinoic acid receptor RXR-alpha	Homo sapiens		 40.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276404&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309659	378158074							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524712	CC(=O)c1cnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)nc1	InChI=1S/C16H12F3N5O3/c1-10(25)11-6-20-15(21-7-11)26-9-12-8-24(23-22-12)13-3-2-4-14(5-13)27-16(17,18)19/h2-8H,9H2,1H3	KKUWJTUGRHRCFJ-UHFFFAOYSA-N	276405	1-[2-[[1-[3-(Trifluoromethoxy)phenyl]triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 344::US10233173, Example 344	Retinoic acid receptor RXR-alpha	Homo sapiens		 62.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276405&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309661	378158075							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524713	CC(C)(O)c1cnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)nc1	InChI=1S/C17H16F3N5O3/c1-16(2,26)11-7-21-15(22-8-11)27-10-12-9-25(24-23-12)13-4-3-5-14(6-13)28-17(18,19)20/h3-9,26H,10H2,1-2H3	GYCBYHREXPLFEP-UHFFFAOYSA-N	276406	2-[2-[[1-[3-(Trifluoromethoxy)phenyl]triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 345::US10233173, Example 345	Retinoic acid receptor RXR-alpha	Homo sapiens		 284					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276406&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309666	378158076							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524714	COCc1ccnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)n1	InChI=1S/C16H14F3N5O3/c1-25-9-11-5-6-20-15(21-11)26-10-12-8-24(23-22-12)13-3-2-4-14(7-13)27-16(17,18)19/h2-8H,9-10H2,1H3	QPLDNTIOUAOGHY-UHFFFAOYSA-N	276407	4-(Methoxymethyl)-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 346::US10233173, Example 346	Retinoic acid receptor RXR-alpha	Homo sapiens		 202					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276407&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309669	378158077							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524715	Cc1ccnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)n1	InChI=1S/C15H12F3N5O2/c1-10-5-6-19-14(20-10)24-9-11-8-23(22-21-11)12-3-2-4-13(7-12)25-15(16,17)18/h2-8H,9H2,1H3	FSNVGTZQYFFMMI-UHFFFAOYSA-N	276408	4-Methyl-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 347::US10233173, Example 347	Retinoic acid receptor RXR-alpha	Homo sapiens		 137					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276408&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309665	378158078							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524716	Fc1cnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)nc1	InChI=1S/C14H9F4N5O2/c15-9-5-19-13(20-6-9)24-8-10-7-23(22-21-10)11-2-1-3-12(4-11)25-14(16,17)18/h1-7H,8H2	WSJJKBLUFAOYMV-UHFFFAOYSA-N	276409	5-Fluoro-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 348::US10233173, Example 348	Retinoic acid receptor RXR-alpha	Homo sapiens		 447					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276409&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309664	378158079							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524717	COc1cnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)nc1	InChI=1S/C15H12F3N5O3/c1-24-13-6-19-14(20-7-13)25-9-10-8-23(22-21-10)11-3-2-4-12(5-11)26-15(16,17)18/h2-8H,9H2,1H3	MFXUAEKLDFKTNX-UHFFFAOYSA-N	276410	5-Methoxy-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 349::US10233173, Example 349	Retinoic acid receptor RXR-alpha	Homo sapiens		 13.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276410&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309670	378158080							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524718	FC(F)(F)Oc1cccc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H9ClF3N5O2/c15-9-5-19-13(20-6-9)24-8-10-7-23(22-21-10)11-2-1-3-12(4-11)25-14(16,17)18/h1-7H,8H2	XDXTYBOYGNCHQI-UHFFFAOYSA-N	276411	5-Chloro-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 350::US10233173, Example 350	Retinoic acid receptor RXR-alpha	Homo sapiens		 50.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276411&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309667	378158081							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524719	CCc1cnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)nc1	InChI=1S/C16H14F3N5O2/c1-2-11-7-20-15(21-8-11)25-10-12-9-24(23-22-12)13-4-3-5-14(6-13)26-16(17,18)19/h3-9H,2,10H2,1H3	FXLVJUCJNSRRFS-UHFFFAOYSA-N	276412	5-Ethyl-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 351::US10233173, Example 351	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276412&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309671	378158082							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524720	CNc1ccnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)n1	InChI=1S/C15H13F3N6O2/c1-19-13-5-6-20-14(21-13)25-9-10-8-24(23-22-10)11-3-2-4-12(7-11)26-15(16,17)18/h2-8H,9H2,1H3,(H,19,20,21)	FQKHQJKZKWCXAU-UHFFFAOYSA-N	276413	N-Methyl-2-[[1-[3-(trifluoromethoxy)phenyl]triazol-4-::US10071988, Example 352::US10233173, Example 352	Retinoic acid receptor RXR-alpha	Homo sapiens		 68.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276413&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309672	378158083							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524721	Nc1ccnc(OCc2cn(nn2)-c2cccc(OC(F)(F)F)c2)n1	InChI=1S/C14H11F3N6O2/c15-14(16,17)25-11-3-1-2-10(6-11)23-7-9(21-22-23)8-24-13-19-5-4-12(18)20-13/h1-7H,8H2,(H2,18,19,20)	WTSYNUMTIRVWBU-UHFFFAOYSA-N	276414	2-[[1-[3-(Trifluoromethoxy)phenyl]triazol-4-yl]methoxy]pyrimidin-4-::US10071988, Example 353::US10233173, Example 353	Retinoic acid receptor RXR-alpha	Homo sapiens		 525					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276414&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309673	378158084							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524722	Cc1cnc(OCc2cn(nn2)-c2ccc3OC(F)(F)Oc3c2)nc1	InChI=1S/C15H11F2N5O3/c1-9-5-18-14(19-6-9)23-8-10-7-22(21-20-10)11-2-3-12-13(4-11)25-15(16,17)24-12/h2-7H,8H2,1H3	JVBPKUGGJXUHNN-UHFFFAOYSA-N	276415	2-[[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)triazol-4-yl]methoxy]-5-::US10071988, Example 354::US10233173, Example 354	Retinoic acid receptor RXR-alpha	Homo sapiens		 73.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276415&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302309	378158085							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524723	FC1(F)Oc2ccc(cc2O1)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H9F2N5O3/c15-14(16)23-11-3-2-10(6-12(11)24-14)21-7-9(19-20-21)8-22-13-17-4-1-5-18-13/h1-7H,8H2	YFAFAQYSYUNTHC-UHFFFAOYSA-N	276416	2-[[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)triazol-4-::US10071988, Example 355::US10233173, Example 355	Retinoic acid receptor RXR-alpha	Homo sapiens		 238					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276416&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302295	378158086							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524724	FC1(F)Oc2ccc(cc2O1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H8ClF2N5O3/c15-8-4-18-13(19-5-8)23-7-9-6-22(21-20-9)10-1-2-11-12(3-10)25-14(16,17)24-11/h1-6H,7H2	HNWMUDHSPWIAKC-UHFFFAOYSA-N	276417	5-Chloro-2-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)triazol-4-::US10071988, Example 356::US10233173, Example 356	Retinoic acid receptor RXR-alpha	Homo sapiens		 185					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276417&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302289	378158087							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524725	Cc1nc(OCc2cn(nn2)-c2ccc3OC(F)(F)Oc3c2)ncc1F	InChI=1S/C15H10F3N5O3/c1-8-11(16)5-19-14(20-8)24-7-9-6-23(22-21-9)10-2-3-12-13(4-10)26-15(17,18)25-12/h2-6H,7H2,1H3	OUCZNGRRBIERAF-UHFFFAOYSA-N	276418	2-[[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)triazol-4-yl]methoxy]-5-::US10071988, Example 357::US10233173, Example 357	Retinoic acid receptor RXR-alpha	Homo sapiens		 350					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276418&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302271	378158088							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524726	Fc1cnc(OCc2cn(nn2)-c2ccc3OC(F)(F)Oc3c2)nc1	InChI=1S/C14H8F3N5O3/c15-8-4-18-13(19-5-8)23-7-9-6-22(21-20-9)10-1-2-11-12(3-10)25-14(16,17)24-11/h1-6H,7H2	VDXLYDOLOJADHO-UHFFFAOYSA-N	276419	2-[[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)triazol-4-yl]methoxy]-5-::US10071988, Example 358::US10233173, Example 358	Retinoic acid receptor RXR-alpha	Homo sapiens		 726					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276419&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302224	378158089							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524727	Cc1cnc(OCc2cn(nn2)-c2ccc3OC(F)(F)Oc3c2)nc1C	InChI=1S/C16H13F2N5O3/c1-9-6-19-15(20-10(9)2)24-8-11-7-23(22-21-11)12-3-4-13-14(5-12)26-16(17,18)25-13/h3-7H,8H2,1-2H3	KCYBTWAFAJHDNZ-UHFFFAOYSA-N	276420	2-[[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)triazol-4-yl]methoxy]-4,5-::US10071988, Example 359::US10233173, Example 359	Retinoic acid receptor RXR-alpha	Homo sapiens		 9.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276420&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302274	378158090							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524728	Cc1cc(C)cc(c1)-n1cc(COc2ncccn2)nn1	InChI=1S/C15H15N5O/c1-11-6-12(2)8-14(7-11)20-9-13(18-19-20)10-21-15-16-4-3-5-17-15/h3-9H,10H2,1-2H3	CUPJRVGFEUEQFZ-UHFFFAOYSA-N	276421	2-[[1-(3,5-Dimethylphenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 360::US10233173, Example 360	Retinoic acid receptor RXR-alpha	Homo sapiens		 791					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276421&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309674	378158091							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524729	Cc1cc(C)cc(c1)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C15H14FN5O/c1-10-3-11(2)5-14(4-10)21-8-13(19-20-21)9-22-15-17-6-12(16)7-18-15/h3-8H,9H2,1-2H3	AZKGGYBXLDIFRP-UHFFFAOYSA-N	276422	2-[[1-(3,5-Dimethylphenyl)triazol-4-yl]methoxy]-5-fluoro-pyrimidine;::US10071988, Example 361::US10233173, Example 361	Retinoic acid receptor RXR-alpha	Homo sapiens		 587					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276422&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309675	378158092							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524730	COc1cnc(OCc2cn(nn2)-c2cc(C)cc(C)c2)nc1	InChI=1S/C16H17N5O2/c1-11-4-12(2)6-14(5-11)21-9-13(19-20-21)10-23-16-17-7-15(22-3)8-18-16/h4-9H,10H2,1-3H3	BQQAHRHHVVWUHO-UHFFFAOYSA-N	276423	2-[[1-(3,5-Dimethylphenyl)triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 362::US10233173, Example 362	Retinoic acid receptor RXR-alpha	Homo sapiens		 32.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276423&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309676	378158093							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524731	Cc1cc(C)cc(c1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C15H14ClN5O/c1-10-3-11(2)5-14(4-10)21-8-13(19-20-21)9-22-15-17-6-12(16)7-18-15/h3-8H,9H2,1-2H3	YLQHVXKJAIVLIK-UHFFFAOYSA-N	276424	5-Chloro-2-[[1-(3,5-dimethylphenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 363::US10233173, Example 363	Retinoic acid receptor RXR-alpha	Homo sapiens		 118					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276424&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309677	378158094							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524732	Cc1cnc(OCc2cn(nn2)-c2cc(C)cc(C)c2)nc1	InChI=1S/C16H17N5O/c1-11-4-12(2)6-15(5-11)21-9-14(19-20-21)10-22-16-17-7-13(3)8-18-16/h4-9H,10H2,1-3H3	DJZXKJVRASUECC-UHFFFAOYSA-N	276425	2-[[1-(3,5-Dimethylphenyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 364::US10233173, Example 364	Retinoic acid receptor RXR-alpha	Homo sapiens		 27.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276425&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309678	378158095							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524733	CCc1cnc(OCc2cn(nn2)-c2cc(C)cc(C)c2)nc1	InChI=1S/C17H19N5O/c1-4-14-8-18-17(19-9-14)23-11-15-10-22(21-20-15)16-6-12(2)5-13(3)7-16/h5-10H,4,11H2,1-3H3	KOQOZRWNLDVJDP-UHFFFAOYSA-N	276426	2-[[1-(3,5-Dimethylphenyl)triazol-4-yl]methoxy]-5-ethyl-pyrimidine;::US10071988, Example 365::US10233173, Example 365	Retinoic acid receptor RXR-alpha	Homo sapiens		 22.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276426&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309679	378158096							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524734	Cc1cnc(OCc2cn(nn2)-c2ccc3CCCc3c2)nc1	InChI=1S/C17H17N5O/c1-12-8-18-17(19-9-12)23-11-15-10-22(21-20-15)16-6-5-13-3-2-4-14(13)7-16/h5-10H,2-4,11H2,1H3	DLPSJNSQVUZJAK-UHFFFAOYSA-N	276427	2-[(1-Indan-5-yltriazol-4-yl)methoxy]-5-methyl-pyrimidine;::US10071988, Example 366::US10233173, Example 366	Retinoic acid receptor RXR-alpha	Homo sapiens		 20.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276427&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309680	378158097							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524735	Clc1cnc(OCc2cn(nn2)-c2ccc3CCCc3c2)nc1	InChI=1S/C16H14ClN5O/c17-13-7-18-16(19-8-13)23-10-14-9-22(21-20-14)15-5-4-11-2-1-3-12(11)6-15/h4-9H,1-3,10H2	REQFIXPMOPLMKE-UHFFFAOYSA-N	276428	5-Chloro-2-[(1-indan-5-yltriazol-4-yl)methoxy]pyrimidine;::US10071988, Example 367::US10233173, Example 367	Retinoic acid receptor RXR-alpha	Homo sapiens		 53.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276428&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309681	378158098							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524736	COCc1ccnc(OCc2cn(nn2)-c2ccc3CCCc3c2)n1	InChI=1S/C18H19N5O2/c1-24-11-15-7-8-19-18(20-15)25-12-16-10-23(22-21-16)17-6-5-13-3-2-4-14(13)9-17/h5-10H,2-4,11-12H2,1H3	WHXANDXGVDVAJI-UHFFFAOYSA-N	276429	2-[(1-Indan-5-yltriazol-4-yl)methoxy]-4-(methoxymethyl)pyrimidine;::US10071988, Example 368::US10233173, Example 368	Retinoic acid receptor RXR-alpha	Homo sapiens		 114					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276429&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302391	378158099							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524737	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc3CCCc3c2)nc1	InChI=1S/C19H21N5O2/c1-19(2,25)15-9-20-18(21-10-15)26-12-16-11-24(23-22-16)17-7-6-13-4-3-5-14(13)8-17/h6-11,25H,3-5,12H2,1-2H3	MJFCRCAGOOVQQT-UHFFFAOYSA-N	276430	2-[2-[(1-Indan-5-yltriazol-4-yl)methoxy]pyrimidin-5-yl]propan-2-ol;::US10071988, Example 369::US10233173, Example 369	Retinoic acid receptor RXR-alpha	Homo sapiens		 175					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276430&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309682	378158100							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524738	FC(F)c1ccnc(OCc2cn(nn2)-c2ccc3CCCc3c2)n1	InChI=1S/C17H15F2N5O/c18-16(19)15-6-7-20-17(21-15)25-10-13-9-24(23-22-13)14-5-4-11-2-1-3-12(11)8-14/h4-9,16H,1-3,10H2	FPFBRAAUXWOZRX-UHFFFAOYSA-N	276431	4-(Difluoromethyl)-2-[(1-indan-5-yltriazol-4-yl)methoxy]pyrimidine;::US10071988, Example 370::US10233173, Example 370	Retinoic acid receptor RXR-alpha	Homo sapiens		 397					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276431&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302388	378158101							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524739	Cc1nc(OCc2cn(nn2)-c2ccc3CCCc3c2)ncc1Cl	InChI=1S/C17H16ClN5O/c1-11-16(18)8-19-17(20-11)24-10-14-9-23(22-21-14)15-6-5-12-3-2-4-13(12)7-15/h5-9H,2-4,10H2,1H3	GRKTXLLGRRASAN-UHFFFAOYSA-N	276432	5-Chloro-2-[(1-indan-5-yltriazol-4-yl)methoxy]-4-methyl-pyrimidine;::US10071988, Example 371::US10233173, Example 371	Retinoic acid receptor RXR-alpha	Homo sapiens		 39.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276432&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302381	378158102							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524740	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1C	InChI=1S/C16H14ClF2N5O2/c1-9-6-20-16(21-10(9)2)25-8-11-7-24(23-22-11)12-3-4-13(17)14(5-12)26-15(18)19/h3-7,15H,8H2,1-2H3	RUOOCYSHEBYYAG-UHFFFAOYSA-N	276433	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-4,5-::US10071988, Example 372::US10233173, Example 372	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276433&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309683	378158103							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524741	CC(C)c1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C17H16ClF2N5O2/c1-10(2)11-6-21-17(22-7-11)26-9-12-8-25(24-23-12)13-3-4-14(18)15(5-13)27-16(19)20/h3-8,10,16H,9H2,1-2H3	ZDIUEJOOFHCSEB-UHFFFAOYSA-N	276434	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 373::US10233173, Example 373	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276434&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309684	378158104							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524742	C[C@@H](Oc1ncccn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H12ClF2N5O2/c1-9(24-15-19-5-2-6-20-15)12-8-23(22-21-12)10-3-4-11(16)13(7-10)25-14(17)18/h2-9,14H,1H3/t9-/m1/s1	WGPIRIWUILWZNN-SECBINFHSA-N	276147	(R*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 374::US10071988, Example 54::US10233173, Example 374	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276147&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302340	378157819							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524743	C[C@@H](Oc1ncc(Cl)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H11Cl2F2N5O2/c1-8(25-15-20-5-9(16)6-21-15)12-7-24(23-22-12)10-2-3-11(17)13(4-10)26-14(18)19/h2-8,14H,1H3/t8-/m1/s1	WFWPOGDKKNYHRY-MRVPVSSYSA-N	276436	5-Chloro-2-[(1R)-1-[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 375::US10233173, Example 375	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276436&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302200	378158105							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524744	C[C@@H](Oc1ncc(C)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H14ClF2N5O2/c1-9-6-20-16(21-7-9)25-10(2)13-8-24(23-22-13)11-3-4-12(17)14(5-11)26-15(18)19/h3-8,10,15H,1-2H3/t10-/m1/s1	QRBOGBACUMUXBQ-SNVBAGLBSA-N	276150	(R*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]ethoxy]-5-methyl-::US10071988, Example 376::US10071988, Example 57::US10233173, Example 376	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276150&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302222	378157822							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524745	COc1cnc(O[C@H](C)c2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C16H14ClF2N5O3/c1-9(26-16-20-6-11(25-2)7-21-16)13-8-24(23-22-13)10-3-4-12(17)14(5-10)27-15(18)19/h3-9,15H,1-2H3/t9-/m1/s1	RGIRVFATLGXRRM-SECBINFHSA-N	276438	2-[(1R)-1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]ethoxy]-::US10071988, Example 377::US10233173, Example 377	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276438&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302243	378158106							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524746	C[C@H](Oc1ncccn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H12ClF2N5O2/c1-9(24-15-19-5-2-6-20-15)12-8-23(22-21-12)10-3-4-11(16)13(7-10)25-14(17)18/h2-9,14H,1H3/t9-/m0/s1	WGPIRIWUILWZNN-VIFPVBQESA-N	276148	(S*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 378::US10071988, Example 55::US10233173, Example 378	Retinoic acid receptor RXR-alpha	Homo sapiens		 2300					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276148&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302325	378157820							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524747	C[C@H](Oc1ncc(Cl)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H11Cl2F2N5O2/c1-8(25-15-20-5-9(16)6-21-15)12-7-24(23-22-12)10-2-3-11(17)13(4-10)26-14(18)19/h2-8,14H,1H3/t8-/m0/s1	WFWPOGDKKNYHRY-QMMMGPOBSA-N	276440	5-Chloro-2-[(1S)-1-[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 379::US10233173, Example 379	Retinoic acid receptor RXR-alpha	Homo sapiens		 575					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276440&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302188	378158107							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524748	C[C@H](Oc1ncc(C)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H14ClF2N5O2/c1-9-6-20-16(21-7-9)25-10(2)13-8-24(23-22-13)11-3-4-12(17)14(5-11)26-15(18)19/h3-8,10,15H,1-2H3/t10-/m0/s1	QRBOGBACUMUXBQ-JTQLQIEISA-N	276151	(S*)-2-[1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]ethoxy]-5-methyl-::US10071988, Example 380::US10071988, Example 58::US10233173, Example 380	Retinoic acid receptor RXR-alpha	Homo sapiens		 237					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276151&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302382	378157823							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524749	C[C@H](Oc1ncc(O)cn1)c1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H12ClF2N5O3/c1-8(25-15-19-5-10(24)6-20-15)12-7-23(22-21-12)9-2-3-11(16)13(4-9)26-14(17)18/h2-8,14,24H,1H3/t8-/m0/s1	MHCNNLUVUKWZKA-QMMMGPOBSA-N	276442	2-[(1S)-1-[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]ethoxy]-::US10071988, Example 381::US10233173, Example 381	Retinoic acid receptor RXR-alpha	Homo sapiens		 196					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276442	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276442&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309685	378158108							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524750	Nc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C14H11ClF2N6O2/c15-10-2-1-9(5-11(10)25-13(16)17)23-6-8(21-22-23)7-24-14-19-4-3-12(18)20-14/h1-6,13H,7H2,(H2,18,19,20)	ITPCHPLVCKJFCH-UHFFFAOYSA-N	276443	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 382::US10233173, Example 382	Retinoic acid receptor RXR-alpha	Homo sapiens		 21.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276443	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276443&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302420	378158109							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524751	OCc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C15H12ClF2N5O3/c16-12-2-1-11(5-13(12)26-14(17)18)23-6-10(21-22-23)8-25-15-19-4-3-9(7-24)20-15/h1-6,14,24H,7-8H2	NOVZXTMURBFPSI-UHFFFAOYSA-N	276444	US10071988, Example 383::US10233173, Example 383::[2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276444&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302227	378158110							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524752	COCc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C16H14ClF2N5O3/c1-25-8-10-4-5-20-16(21-10)26-9-11-7-24(23-22-11)12-2-3-13(17)14(6-12)27-15(18)19/h2-7,15H,8-9H2,1H3	CNNUWKCPYKEWEB-UHFFFAOYSA-N	276445	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 384::US10233173, Example 384	Retinoic acid receptor RXR-alpha	Homo sapiens		 18.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276445&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309686	378158111							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524753	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)nc1	InChI=1S/C17H16ClF2N5O3/c1-17(2,26)10-6-21-16(22-7-10)27-9-11-8-25(24-23-11)12-3-4-13(18)14(5-12)28-15(19)20/h3-8,15,26H,9H2,1-2H3	IMFSOXWKBGKOBT-UHFFFAOYSA-N	276446	2-[2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 385::US10233173, Example 385	Retinoic acid receptor RXR-alpha	Homo sapiens		 28.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276446&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309687	378158112							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524754	CC(C)Oc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C17H16ClF2N5O3/c1-10(2)27-15-5-6-21-17(22-15)26-9-11-8-25(24-23-11)12-3-4-13(18)14(7-12)28-16(19)20/h3-8,10,16H,9H2,1-2H3	GOUYNRJIDVZNKB-UHFFFAOYSA-N	276447	2-((1-(4-Chloro-3-(difluoromethoxy)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 386::US10233173, Example 386	Retinoic acid receptor RXR-alpha	Homo sapiens		 504					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276447&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302360	378158113							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524755	COC(=O)c1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C16H12ClF2N5O4/c1-26-14(25)12-4-5-20-16(21-12)27-8-9-7-24(23-22-9)10-2-3-11(17)13(6-10)28-15(18)19/h2-7,15H,8H2,1H3	ZQBJEQCTIAOATB-UHFFFAOYSA-N	276448	Methyl 2-((1-(4-chloro-3-(difluoromethoxy)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 387::US10233173, Example 387	Retinoic acid receptor RXR-alpha	Homo sapiens		 68.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276448&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302220	378158114							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524756	FC(F)CNc1nc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)ncc1F	InChI=1S/C16H12ClF5N6O2/c17-10-2-1-9(3-12(10)30-15(21)22)28-6-8(26-27-28)7-29-16-24-4-11(18)14(25-16)23-5-13(19)20/h1-4,6,13,15H,5,7H2,(H,23,24,25)	HCLBEICYOSVHSY-UHFFFAOYSA-N	276449	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 388::US10233173, Example 388	Retinoic acid receptor RXR-alpha	Homo sapiens		 842					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276449	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276449&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309688	378158115							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524757	CNc1nc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)ncc1F	InChI=1S/C15H12ClF3N6O2/c1-20-13-11(17)5-21-15(22-13)26-7-8-6-25(24-23-8)9-2-3-10(16)12(4-9)27-14(18)19/h2-6,14H,7H2,1H3,(H,20,21,22)	YYHGPWMNUPNDBB-UHFFFAOYSA-N	276450	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 389::US10233173, Example 389	Retinoic acid receptor RXR-alpha	Homo sapiens		 33.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276450&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309689	378158116							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524758	Nc1nc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)ncc1F	InChI=1S/C14H10ClF3N6O2/c15-9-2-1-8(3-11(9)26-13(17)18)24-5-7(22-23-24)6-25-14-20-4-10(16)12(19)21-14/h1-5,13H,6H2,(H2,19,20,21)	IUIDXVARBCARLT-UHFFFAOYSA-N	276451	2-((1-(4-Chloro-3-(difluoromethoxy)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 390::US10233173, Example 390	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276451	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276451&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302314	378158117							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524759	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(cn2)N2CCC2)nn1	InChI=1S/C17H15ClF2N6O2/c18-14-3-2-12(6-15(14)28-16(19)20)26-9-11(23-24-26)10-27-17-21-7-13(8-22-17)25-4-1-5-25/h2-3,6-9,16H,1,4-5,10H2	SJEHNWGEZJSGGR-UHFFFAOYSA-N	276452	5-(Azetidin-1-yl)-2-((1-(4-chloro-3-(difluoromethoxy)phenyl)-1H-::US10071988, Example 391::US10233173, Example 391	Retinoic acid receptor RXR-alpha	Homo sapiens		 22.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276452&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302276	378158118							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524760	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(cn2)N2CC(F)C2)nn1	InChI=1S/C17H14ClF3N6O2/c18-14-2-1-12(3-15(14)29-16(20)21)27-8-11(24-25-27)9-28-17-22-4-13(5-23-17)26-6-10(19)7-26/h1-5,8,10,16H,6-7,9H2	UWEWXPRCANLMFH-UHFFFAOYSA-N	276453	2-((1-(4-Chloro-3-(difluoromethoxy)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 392::US10233173, Example 392	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276453&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302424	378158119							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524761	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(cn2)N2CC(F)(F)C2)nn1	InChI=1S/C17H13ClF4N6O2/c18-13-2-1-11(3-14(13)30-15(19)20)28-6-10(25-26-28)7-29-16-23-4-12(5-24-16)27-8-17(21,22)9-27/h1-6,15H,7-9H2	RPUPAOLBYKPZPU-UHFFFAOYSA-N	276454	2-((1-(4-Chloro-3-(difluoromethoxy)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 393::US10233173, Example 393	Retinoic acid receptor RXR-alpha	Homo sapiens		 37.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276454&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302322	378158120							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524762	FC(F)Oc1cc(ccc1Cl)-n1cc(COc2cccc(F)n2)nn1	InChI=1S/C15H10ClF3N4O2/c16-11-5-4-10(6-12(11)25-15(18)19)23-7-9(21-22-23)8-24-14-3-1-2-13(17)20-14/h1-7,15H,8H2	XMDAYFWPESDHLK-UHFFFAOYSA-N	276455	2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-6-::US10071988, Example 394::US10233173, Example 394	Retinoic acid receptor RXR-alpha	Homo sapiens		 437					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276455&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309690	378158121							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524763	FC(F)Oc1cc(ccc1F)-n1cc(COc2cccc(n2)C(F)(F)F)nn1	InChI=1S/C16H10F6N4O2/c17-11-5-4-10(6-12(11)28-15(18)19)26-7-9(24-25-26)8-27-14-3-1-2-13(23-14)16(20,21)22/h1-7,15H,8H2	BSEQRVJJOUHIHU-UHFFFAOYSA-N	276456	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-6-::US10071988, Example 395	Retinoic acid receptor RXR-alpha	Homo sapiens		 919					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276456&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309691	378158122							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524764	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)cn1	InChI=1S/C15H12F3N5O2/c1-9-5-20-14(6-19-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(4-11)25-15(17)18/h2-7,15H,8H2,1H3	GSRUSKIBTUAFGX-UHFFFAOYSA-N	276457	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 396::US10233173, Example 396	Retinoic acid receptor RXR-alpha	Homo sapiens		 647					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276457&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309692	378158123							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524765	FC(F)Oc1cc(ccc1F)-n1cc(COc2cnc(cn2)-c2cccs2)nn1	InChI=1S/C18H12F3N5O2S/c19-13-4-3-12(6-15(13)28-18(20)21)26-9-11(24-25-26)10-27-17-8-22-14(7-23-17)16-2-1-5-29-16/h1-9,18H,10H2	OWAXOMQRERBNBL-UHFFFAOYSA-N	276458	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-(2-::US10071988, Example 397::US10233173, Example 397	Retinoic acid receptor RXR-alpha	Homo sapiens		 10700					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276458&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309693	378158124							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524766	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(Br)cn2)nn1	InChI=1S/C14H9BrF3N5O/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-12(16)11(3-10)13(17)18/h1-6,13H,7H2	GGIDVPDWWXIYLD-UHFFFAOYSA-N	276459	5-Bromo-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 398::US10233173, Example 398	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276459&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302460	378158125							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524767	COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C16H14F3N5O2/c1-25-8-10-4-5-20-16(21-10)26-9-11-7-24(23-22-11)12-2-3-14(17)13(6-12)15(18)19/h2-7,15H,8-9H2,1H3	IITSEHBVCHOHKB-UHFFFAOYSA-N	276460	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 399::US10233173, Example 399	Retinoic acid receptor RXR-alpha	Homo sapiens		 23.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276460&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309694	378158126							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524768	OCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C15H12F3N5O2/c16-13-2-1-11(5-12(13)14(17)18)23-6-10(21-22-23)8-25-15-19-4-3-9(7-24)20-15/h1-6,14,24H,7-8H2	GGBOAANJGZQHOY-UHFFFAOYSA-N	276461	US10071988, Example 400::US10233173, Example 400::[2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 36.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276461&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309695	378158127							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524769	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C17H16F3N5O2/c1-17(2,26)10-6-21-16(22-7-10)27-9-11-8-25(24-23-11)12-3-4-14(18)13(5-12)15(19)20/h3-8,15,26H,9H2,1-2H3	MWSHOQRGNMWBBL-UHFFFAOYSA-N	276462	2-[2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 401::US10233173, Example 401	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276462&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309696	378158128							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524770	FC(F)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C15H10F5N5O/c16-11-2-1-9(5-10(11)13(17)18)25-6-8(23-24-25)7-26-15-21-4-3-12(22-15)14(19)20/h1-6,13-14H,7H2	SOXCWMDWEVKWNP-UHFFFAOYSA-N	276463	4-(Difluoromethyl)-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 402::US10233173, Example 402	Retinoic acid receptor RXR-alpha	Homo sapiens		 51.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276463&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309702	378158129							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524771	FC(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)C(F)(F)F)nn1	InChI=1S/C15H9F6N5O/c16-11-2-1-9(5-10(11)13(17)18)26-6-8(24-25-26)7-27-14-22-4-3-12(23-14)15(19,20)21/h1-6,13H,7H2	HNOMZSWJEWCOEX-UHFFFAOYSA-N	276464	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 403::US10233173, Example 403	Retinoic acid receptor RXR-alpha	Homo sapiens		 199					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276464	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276464&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309697	378158130							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524772	CC(O)(c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1)C(F)(F)F	InChI=1S/C17H13F6N5O2/c1-16(29,17(21,22)23)9-5-24-15(25-6-9)30-8-10-7-28(27-26-10)11-2-3-13(18)12(4-11)14(19)20/h2-7,14,29H,8H2,1H3	XAFDHONMCUVXLI-UHFFFAOYSA-N	276465	(R/S)-2-[2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 404::US10233173, Example 404	Retinoic acid receptor RXR-alpha	Homo sapiens		 482					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276465&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309699	378158131							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524773	FC(F)Oc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C15H10F5N5O2/c16-12-2-1-9(3-11(12)13(17)18)25-6-8(23-24-25)7-26-15-21-4-10(5-22-15)27-14(19)20/h1-6,13-14H,7H2	XWESTTALODFMOA-UHFFFAOYSA-N	276466	5-(Difluoromethoxy)-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-::US10071988, Example 405::US10233173, Example 405	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276466&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309698	378158132							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524774	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)ncc1Cl	InChI=1S/C15H11ClF3N5O/c1-8-12(16)5-20-15(21-8)25-7-9-6-24(23-22-9)10-2-3-13(17)11(4-10)14(18)19/h2-6,14H,7H2,1H3	RXLRURYBQIBHOJ-UHFFFAOYSA-N	276467	5-Chloro-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 406::US10233173, Example 406	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276467&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309700	378158133							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524775	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)ncc1F	InChI=1S/C15H11F4N5O/c1-8-13(17)5-20-15(21-8)25-7-9-6-24(23-22-9)10-2-3-12(16)11(4-10)14(18)19/h2-6,14H,7H2,1H3	GYZVAUNIHWKONN-UHFFFAOYSA-N	276468	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 407::US10233173, Example 407	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276468&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309701	378158134							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524776	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1C	InChI=1S/C16H14F3N5O/c1-9-6-20-16(21-10(9)2)25-8-11-7-24(23-22-11)12-3-4-14(17)13(5-12)15(18)19/h3-7,15H,8H2,1-2H3	NVGYKVFFMQKJJU-UHFFFAOYSA-N	276469	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4,5-::US10071988, Example 408::US10233173, Example 408	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276469&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309706	378158135							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524777	CNC(=O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C16H13F3N6O2/c1-20-15(26)9-5-21-16(22-6-9)27-8-10-7-25(24-23-10)11-2-3-13(17)12(4-11)14(18)19/h2-7,14H,8H2,1H3,(H,20,26)	HOZCQZKDIQGWHJ-UHFFFAOYSA-N	276470	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 409::US10233173, Example 409	Retinoic acid receptor RXR-alpha	Homo sapiens		 149					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276470&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309704	378158136							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524778	CN(C)C(=O)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C17H15F3N6O2/c1-25(2)16(27)14-5-6-21-17(22-14)28-9-10-8-26(24-23-10)11-3-4-13(18)12(7-11)15(19)20/h3-8,15H,9H2,1-2H3	BUBCUPIBXYEODD-UHFFFAOYSA-N	276471	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N,N-::US10071988, Example 410::US10233173, Example 410	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276471&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309705	378158137							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524779	COc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)ncc1C	InChI=1S/C16H14F3N5O2/c1-9-6-20-16(21-15(9)25-2)26-8-10-7-24(23-22-10)11-3-4-13(17)12(5-11)14(18)19/h3-7,14H,8H2,1-2H3	LLDDJSSEVCBSNA-UHFFFAOYSA-N	276472	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 411::US10233173, Example 411	Retinoic acid receptor RXR-alpha	Homo sapiens		 21.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276472&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309703	378158138							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524780	Nc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C14H11F3N6O/c15-11-2-1-9(5-10(11)13(16)17)23-6-8(21-22-23)7-24-14-19-4-3-12(18)20-14/h1-6,13H,7H2,(H2,18,19,20)	FIOPFFJFSQYURG-UHFFFAOYSA-N	276473	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 412::US10233173, Example 412	Retinoic acid receptor RXR-alpha	Homo sapiens		 124					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276473&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309707	378158139							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524781	CNc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C15H13F3N6O/c1-19-13-4-5-20-15(21-13)25-8-9-7-24(23-22-9)10-2-3-12(16)11(6-10)14(17)18/h2-7,14H,8H2,1H3,(H,19,20,21)	PJRNVVYBYALHKB-UHFFFAOYSA-N	276474	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 413::US10233173, Example 413	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276474&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309708	378158140							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524782	CNc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)ncc1F	InChI=1S/C15H12F4N6O/c1-20-14-12(17)5-21-15(22-14)26-7-8-6-25(24-23-8)9-2-3-11(16)10(4-9)13(18)19/h2-6,13H,7H2,1H3,(H,20,21,22)	IJLIJZFPZGZSNP-UHFFFAOYSA-N	276475	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 414::US10233173, Example 414	Retinoic acid receptor RXR-alpha	Homo sapiens		 122					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276475&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309709	378158141							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524783	CN(C)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C16H15F3N6O/c1-24(2)14-5-6-20-16(21-14)26-9-10-8-25(23-22-10)11-3-4-13(17)12(7-11)15(18)19/h3-8,15H,9H2,1-2H3	ZPEHMQJWIRCTMZ-UHFFFAOYSA-N	276476	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N,N-::US10071988, Example 415::US10233173, Example 415	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276476&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309710	378158142							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524784	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CC(F)C2)nn1	InChI=1S/C17H14F4N6O/c18-10-6-26(7-10)13-4-22-17(23-5-13)28-9-11-8-27(25-24-11)12-1-2-15(19)14(3-12)16(20)21/h1-5,8,10,16H,6-7,9H2	LROJYCXLRQMHAI-UHFFFAOYSA-N	276477	2-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 416::US10233173, Example 416	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276477&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302293	378158143							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524785	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CCC2)nn1	InChI=1S/C17H15F3N6O/c18-15-3-2-12(6-14(15)16(19)20)26-9-11(23-24-26)10-27-17-21-7-13(8-22-17)25-4-1-5-25/h2-3,6-9,16H,1,4-5,10H2	NZLJVPQMNZXNHQ-UHFFFAOYSA-N	276478	5-(Azetidin-1-yl)-2-((1-(3-(difluoromethyl)-4-fluorophenyl)-1H-1,2,3-::US10071988, Example 417::US10233173, Example 417	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276478&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302272	378158144							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524786	COC1CN(C1)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C18H17F3N6O2/c1-28-14-8-26(9-14)13-5-22-18(23-6-13)29-10-11-7-27(25-24-11)12-2-3-16(19)15(4-12)17(20)21/h2-7,14,17H,8-10H2,1H3	KYFDTDRUTJEBPO-UHFFFAOYSA-N	276479	2-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 418::US10233173, Example 418	Retinoic acid receptor RXR-alpha	Homo sapiens		 271					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276479&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302421	378158145							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524787	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CC(F)(F)C2)nn1	InChI=1S/C17H13F5N6O/c18-14-2-1-11(3-13(14)15(19)20)28-6-10(25-26-28)7-29-16-23-4-12(5-24-16)27-8-17(21,22)9-27/h1-6,15H,7-9H2	MNQLZJMBMWVFPM-UHFFFAOYSA-N	276480	5-(3,3-Difluoroazetidin-1-yl)-2-((1-(3-(difluoromethyl)-4-::US10071988, Example 419::US10233173, Example 419	Retinoic acid receptor RXR-alpha	Homo sapiens		 29.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276480&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302284	378158146							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524788	CC1(F)CN(C1)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C18H16F4N6O/c1-18(22)9-27(10-18)13-5-23-17(24-6-13)29-8-11-7-28(26-25-11)12-2-3-15(19)14(4-12)16(20)21/h2-7,16H,8-10H2,1H3	NMEDYVWGPXZPSY-UHFFFAOYSA-N	276481	2-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 420::US10233173, Example 420	Retinoic acid receptor RXR-alpha	Homo sapiens		 260					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276481&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309711	378158147							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524789	FC(F)C1CN(C1)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C18H15F5N6O/c19-15-2-1-12(3-14(15)17(22)23)29-8-11(26-27-29)9-30-18-24-4-13(5-25-18)28-6-10(7-28)16(20)21/h1-5,8,10,16-17H,6-7,9H2	FMMLJBYMTPACDW-UHFFFAOYSA-N	276482	2-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 421::US10233173, Example 421	Retinoic acid receptor RXR-alpha	Homo sapiens		 227					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276482&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302356	378158148							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524790	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CCC(F)(F)C2)nn1	InChI=1S/C18H15F5N6O/c19-15-2-1-12(5-14(15)16(20)21)29-8-11(26-27-29)9-30-17-24-6-13(7-25-17)28-4-3-18(22,23)10-28/h1-2,5-8,16H,3-4,9-10H2	XYFMTQICDRKSTF-UHFFFAOYSA-N	276483	2-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 422::US10233173, Example 422	Retinoic acid receptor RXR-alpha	Homo sapiens		 68.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276483&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302333	378158149							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524791	FC(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C17H14F3N5O/c18-15-4-3-13(5-14(15)16(19)20)25-8-12(23-24-25)9-26-17-21-6-11(7-22-17)10-1-2-10/h3-8,10,16H,1-2,9H2	KWVWYGHSLLYKEQ-UHFFFAOYSA-N	276484	5-Cyclopropyl-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 423::US10233173, Example 423	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276484&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309712	378158150							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524792	FC(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)-c2ccco2)nn1	InChI=1S/C18H12F3N5O2/c19-14-4-3-12(8-13(14)17(20)21)26-9-11(24-25-26)10-28-18-22-6-5-15(23-18)16-2-1-7-27-16/h1-9,17H,10H2	PSMSPJKEWUYWRO-UHFFFAOYSA-N	276485	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-(2-::US10071988, Example 424::US10233173, Example 424	Retinoic acid receptor RXR-alpha	Homo sapiens		 141					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276485&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309715	378158151							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524793	Cc1cnc(OCc2nnn(c2I)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C15H11F3IN5O/c1-8-5-20-15(21-6-8)25-7-12-14(19)24(23-22-12)9-2-3-11(16)10(4-9)13(17)18/h2-6,13H,7H2,1H3	OTHVWCKJQYWJSG-UHFFFAOYSA-N	276486	2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]-5-iodo-triazol-4-::US10071988, Example 425	Retinoic acid receptor RXR-alpha	Homo sapiens		 394					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276486&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302403	378158152							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524794	Fc1cccnc1OCc1cn(nn1)-c1ccc(F)c(c1)C(F)(F)F	InChI=1S/C15H9F5N4O/c16-12-4-3-10(6-11(12)15(18,19)20)24-7-9(22-23-24)8-25-14-13(17)2-1-5-21-14/h1-7H,8H2	RCOAKZLAKFWONK-UHFFFAOYSA-N	276487	3-Fluoro-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 427::US10233173, Example 427	Retinoic acid receptor RXR-alpha	Homo sapiens		 897					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276487&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309716	378158153							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524795	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ccc(Cl)cn2)nn1	InChI=1S/C15H9ClF4N4O/c16-9-1-4-14(21-6-9)25-8-10-7-24(23-22-10)11-2-3-13(17)12(5-11)15(18,19)20/h1-7H,8H2	CIPPVTIHHWNQOI-UHFFFAOYSA-N	276488	5-Chloro-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 428::US10233173, Example 428	Retinoic acid receptor RXR-alpha	Homo sapiens		 796					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276488&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309713	378158154							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524796	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)c1	InChI=1S/C16H12F4N4O/c1-10-4-5-21-15(6-10)25-9-11-8-24(23-22-11)12-2-3-14(17)13(7-12)16(18,19)20/h2-8H,9H2,1H3	LRSHDGFRXVCQIH-UHFFFAOYSA-N	276489	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 429::US10233173, Example 429	Retinoic acid receptor RXR-alpha	Homo sapiens		 665					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276489&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309717	378158155							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524797	Cc1cccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)n1	InChI=1S/C16H12F4N4O/c1-10-3-2-4-15(21-10)25-9-11-8-24(23-22-11)12-5-6-14(17)13(7-12)16(18,19)20/h2-8H,9H2,1H3	YKOHWXYPXNBGFB-UHFFFAOYSA-N	276490	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-6-::US10071988, Example 430::US10233173, Example 430	Retinoic acid receptor RXR-alpha	Homo sapiens		 110					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276490&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309719	378158156							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524798	Cc1ccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H12F4N4O/c1-10-2-5-15(21-7-10)25-9-11-8-24(23-22-11)12-3-4-14(17)13(6-12)16(18,19)20/h2-8H,9H2,1H3	TWEQLFVHDZNYBO-UHFFFAOYSA-N	276491	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 431::US10233173, Example 431	Retinoic acid receptor RXR-alpha	Homo sapiens		 101					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276491&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309718	378158157							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524799	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ccc(cn2)C(F)(F)F)nn1	InChI=1S/C16H9F7N4O/c17-13-3-2-11(5-12(13)16(21,22)23)27-7-10(25-26-27)8-28-14-4-1-9(6-24-14)15(18,19)20/h1-7H,8H2	HDOZUOIBFDWFOA-UHFFFAOYSA-N	276492	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 432::US10233173, Example 432	Retinoic acid receptor RXR-alpha	Homo sapiens		 528					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276492&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309720	378158158							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524800	CC(C)(O)c1ccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C18H16F4N4O2/c1-17(2,27)11-3-6-16(23-8-11)28-10-12-9-26(25-24-12)13-4-5-15(19)14(7-13)18(20,21)22/h3-9,27H,10H2,1-2H3	PSSSOMGNLHIYSC-UHFFFAOYSA-N	276493	2-[6-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-3-::US10071988, Example 433::US10233173, Example 433	Retinoic acid receptor RXR-alpha	Homo sapiens		 1114					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276493&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309727	378158159							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524801	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2cnccn2)nn1	InChI=1S/C14H9F4N5O/c15-12-2-1-10(5-11(12)14(16,17)18)23-7-9(21-22-23)8-24-13-6-19-3-4-20-13/h1-7H,8H2	XLGWEGHCDXRQQQ-UHFFFAOYSA-N	276494	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 434::US10233173, Example 434	Retinoic acid receptor RXR-alpha	Homo sapiens		 6390					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276494&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309728	378158160							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524802	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C17H15F4N5O2/c1-16(2,27)10-6-22-15(23-7-10)28-9-11-8-26(25-24-11)12-3-4-14(18)13(5-12)17(19,20)21/h3-8,27H,9H2,1-2H3	UKSXSZFTWFMSOX-UHFFFAOYSA-N	276495	2-[2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 435::US10233173, Example 435	Retinoic acid receptor RXR-alpha	Homo sapiens		 98.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276495&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302378	378158161							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524803	COC(C)(C)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C18H17F4N5O2/c1-17(2,28-3)11-7-23-16(24-8-11)29-10-12-9-27(26-25-12)13-4-5-15(19)14(6-13)18(20,21)22/h4-9H,10H2,1-3H3	RDPIDUSACSRWAA-UHFFFAOYSA-N	276496	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-(1-::US10071988, Example 436::US10233173, Example 436	Retinoic acid receptor RXR-alpha	Homo sapiens		 3260					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276496&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309722	378158162							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524804	COCc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H13F4N5O2/c1-26-8-10-5-21-15(22-6-10)27-9-11-7-25(24-23-11)12-2-3-14(17)13(4-12)16(18,19)20/h2-7H,8-9H2,1H3	ZODDYVLEFWKLKN-UHFFFAOYSA-N	276497	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 437::US10233173, Example 437	Retinoic acid receptor RXR-alpha	Homo sapiens		 71.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276497&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309721	378158163							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524805	COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)n1	InChI=1S/C16H13F4N5O2/c1-26-8-10-4-5-21-15(22-10)27-9-11-7-25(24-23-11)12-2-3-14(17)13(6-12)16(18,19)20/h2-7H,8-9H2,1H3	UBHLPZYTSAGZFZ-UHFFFAOYSA-N	276498	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 438::US10233173, Example 438	Retinoic acid receptor RXR-alpha	Homo sapiens		 94.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276498&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309723	378158164							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524806	FC(F)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C15H9F6N5O/c16-12-2-1-10(3-11(12)15(19,20)21)26-6-9(24-25-26)7-27-14-22-4-8(5-23-14)13(17)18/h1-6,13H,7H2	CGXOTJYFVDFFGR-UHFFFAOYSA-N	276499	5-(Difluoromethyl)-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 439::US10233173, Example 439	Retinoic acid receptor RXR-alpha	Homo sapiens		 13.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276499&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309724	378158165							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524807	FC(F)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)n1	InChI=1S/C15H9F6N5O/c16-11-2-1-9(5-10(11)15(19,20)21)26-6-8(24-25-26)7-27-14-22-4-3-12(23-14)13(17)18/h1-6,13H,7H2	YRSNBBYARBNFDY-UHFFFAOYSA-N	276500	4-(Difluoromethyl)-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 440::US10233173, Example 440	Retinoic acid receptor RXR-alpha	Homo sapiens		 98.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276500&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309725	378158166							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524808	CC(O)(c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1)C(F)(F)F	InChI=1S/C17H12F7N5O2/c1-15(30,17(22,23)24)9-5-25-14(26-6-9)31-8-10-7-29(28-27-10)11-2-3-13(18)12(4-11)16(19,20)21/h2-7,30H,8H2,1H3	SXAZMHBGPBPIRU-UHFFFAOYSA-N	276501	(R/S)-1,1,1-Trifluoro-2-[2-[[1-[4-fluoro-3-::US10071988, Example 441::US10233173, Example 441	Retinoic acid receptor RXR-alpha	Homo sapiens		 412					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276501&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309726	378158167							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524809	COc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)n1	InChI=1S/C15H11F4N5O2/c1-25-13-4-5-20-14(21-13)26-8-9-7-24(23-22-9)10-2-3-12(16)11(6-10)15(17,18)19/h2-7H,8H2,1H3	OANZIXJAISORIT-UHFFFAOYSA-N	276502	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 442::US10233173, Example 442	Retinoic acid receptor RXR-alpha	Homo sapiens		 72.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276502&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309729	378158168							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524810	CCOc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H13F4N5O2/c1-2-26-12-6-21-15(22-7-12)27-9-10-8-25(24-23-10)11-3-4-14(17)13(5-11)16(18,19)20/h3-8H,2,9H2,1H3	UTZKFDBJHDVNHP-UHFFFAOYSA-N	276503	5-Ethoxy-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 443::US10233173, Example 443	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276503&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309730	378158169							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524811	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)ncc1Cl	InChI=1S/C15H10ClF4N5O/c1-8-12(16)5-21-14(22-8)26-7-9-6-25(24-23-9)10-2-3-13(17)11(4-10)15(18,19)20/h2-6H,7H2,1H3	XGMDOIBDLYIGIR-UHFFFAOYSA-N	276504	5-Chloro-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 444::US10233173, Example 444	Retinoic acid receptor RXR-alpha	Homo sapiens		 13.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276504&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302433	378158170							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524812	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)ncc1F	InChI=1S/C15H10F5N5O/c1-8-13(17)5-21-14(22-8)26-7-9-6-25(24-23-9)10-2-3-12(16)11(4-10)15(18,19)20/h2-6H,7H2,1H3	IBIWQUFITROCFD-UHFFFAOYSA-N	276505	5-Fluoro-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 445::US10233173, Example 445	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276505&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309731	378158171							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524813	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1C	InChI=1S/C16H13F4N5O/c1-9-6-21-15(22-10(9)2)26-8-11-7-25(24-23-11)12-3-4-14(17)13(5-12)16(18,19)20/h3-7H,8H2,1-2H3	CUIQKUCYAGGRNQ-UHFFFAOYSA-N	276506	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-4,5-::US10071988, Example 446::US10233173, Example 446	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276506&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309732	378158172							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524814	CC(=O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H11F4N5O2/c1-9(26)10-5-21-15(22-6-10)27-8-11-7-25(24-23-11)12-2-3-14(17)13(4-12)16(18,19)20/h2-7H,8H2,1H3	PGHYKQGKLVXRFZ-UHFFFAOYSA-N	276507	1-[2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 447::US10233173, Example 447	Retinoic acid receptor RXR-alpha	Homo sapiens		 14.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276507&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302386	378158173							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524815	CC(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H13F4N5O2/c1-9(26)10-5-21-15(22-6-10)27-8-11-7-25(24-23-11)12-2-3-14(17)13(4-12)16(18,19)20/h2-7,9,26H,8H2,1H3	YNRIRGBEDNUPFT-UHFFFAOYSA-N	276508	(R/S)-1-[2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 448::US10233173, Example 448	Retinoic acid receptor RXR-alpha	Homo sapiens		 31.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276508&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309734	378158174							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524816	CNc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)n1	InChI=1S/C15H12F4N6O/c1-20-13-4-5-21-14(22-13)26-8-9-7-25(24-23-9)10-2-3-12(16)11(6-10)15(17,18)19/h2-7H,8H2,1H3,(H,20,21,22)	PXJAIPSTKXEJJZ-UHFFFAOYSA-N	276509	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 449::US10233173, Example 449	Retinoic acid receptor RXR-alpha	Homo sapiens		 34.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276509&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309735	378158175							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524817	CN(C)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)n1	InChI=1S/C16H14F4N6O/c1-25(2)14-5-6-21-15(22-14)27-9-10-8-26(24-23-10)11-3-4-13(17)12(7-11)16(18,19)20/h3-8H,9H2,1-2H3	WSGRCCGHPXUJIX-UHFFFAOYSA-N	276510	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-N,N-::US10071988, Example 450::US10233173, Example 450	Retinoic acid receptor RXR-alpha	Homo sapiens		 30.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276510&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309738	378158176							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524818	CNc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)ncc1F	InChI=1S/C15H11F5N6O/c1-21-13-12(17)5-22-14(23-13)27-7-8-6-26(25-24-8)9-2-3-11(16)10(4-9)15(18,19)20/h2-6H,7H2,1H3,(H,21,22,23)	RGYJFONIFKLBFU-UHFFFAOYSA-N	276511	5-Fluoro-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 451::US10233173, Example 451	Retinoic acid receptor RXR-alpha	Homo sapiens		 298					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276511&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309733	378158177							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524819	CNC(=O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H12F4N6O2/c1-21-14(27)9-5-22-15(23-6-9)28-8-10-7-26(25-24-10)11-2-3-13(17)12(4-11)16(18,19)20/h2-7H,8H2,1H3,(H,21,27)	OABQISRZJRIOGY-UHFFFAOYSA-N	276512	2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 452::US10233173, Example 452	Retinoic acid receptor RXR-alpha	Homo sapiens		 218					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276512&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309736	378158178							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524820	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C17H13F4N5O/c18-15-4-3-13(5-14(15)17(19,20)21)26-8-12(24-25-26)9-27-16-22-6-11(7-23-16)10-1-2-10/h3-8,10H,1-2,9H2	BHKXAZHMJIXWDG-UHFFFAOYSA-N	276513	5-Cyclopropyl-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 453::US10233173, Example 453	Retinoic acid receptor RXR-alpha	Homo sapiens		 22.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276513&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309737	378158179							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524821	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ncc(Br)cn2)nn1	InChI=1S/C14H8BrF4N5O/c15-8-4-20-13(21-5-8)25-7-9-6-24(23-22-9)10-1-2-12(16)11(3-10)14(17,18)19/h1-6H,7H2	CAEWSEUDIIPHQQ-UHFFFAOYSA-N	276514	5-Bromo-2-((1-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 454::US10233173, Example 454	Retinoic acid receptor RXR-alpha	Homo sapiens		 13.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276514&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302285	378158180							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524822	FC1CN(C1)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C17H13F5N6O/c18-10-6-27(7-10)13-4-23-16(24-5-13)29-9-11-8-28(26-25-11)12-1-2-15(19)14(3-12)17(20,21)22/h1-5,8,10H,6-7,9H2	BVZWNLJNUBOVOH-UHFFFAOYSA-N	276515	2-((1-(4-Fluoro-3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 455::US10233173, Example 455	Retinoic acid receptor RXR-alpha	Homo sapiens		 34.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276515&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302236	378158181							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524823	Fc1ccc(cc1C(F)(F)F)-n1cc(COc2ncc(cn2)N2CCOCC2)nn1	InChI=1S/C18H16F4N6O2/c19-16-2-1-13(7-15(16)18(20,21)22)28-10-12(25-26-28)11-30-17-23-8-14(9-24-17)27-3-5-29-6-4-27/h1-2,7-10H,3-6,11H2	VWRMATIZTSJUNF-UHFFFAOYSA-N	276516	4-(2-((1-(4-Fluoro-3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 456::US10233173, Example 456	Retinoic acid receptor RXR-alpha	Homo sapiens		 500					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276516&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302299	378158182							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524824	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)ncc1N1CCC1	InChI=1S/C18H16F4N6O/c1-11-16(27-5-2-6-27)8-23-17(24-11)29-10-12-9-28(26-25-12)13-3-4-15(19)14(7-13)18(20,21)22/h3-4,7-9H,2,5-6,10H2,1H3	YIRFYACDEHYKGE-UHFFFAOYSA-N	276517	5-(Azetidin-1-yl)-2-((1-(3-(trifluoromethyl)-4-fluorophenyl)-1H-1,2,3-::US10071988, Example 457::US10233173, Example 457	Retinoic acid receptor RXR-alpha	Homo sapiens		 296					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276517&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302221	378158183							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524825	CCNc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1C	InChI=1S/C17H16F4N6O/c1-3-22-15-7-23-16(24-10(15)2)28-9-11-8-27(26-25-11)12-4-5-14(18)13(6-12)17(19,20)21/h4-8,22H,3,9H2,1-2H3	RTCMTIFMMOQDNF-UHFFFAOYSA-N	276518	2-((1-(3-(Trifluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 458::US10233173, Example 458	Retinoic acid receptor RXR-alpha	Homo sapiens		 439					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276518&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302283	378158184							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524826	CCNc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C16H14F4N6O/c1-2-21-10-6-22-15(23-7-10)27-9-11-8-26(25-24-11)12-3-4-14(17)13(5-12)16(18,19)20/h3-8,21H,2,9H2,1H3	WXMILEPINQXAOO-UHFFFAOYSA-N	276519	2-((1-(3-(Trifluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 459::US10233173, Example 459	Retinoic acid receptor RXR-alpha	Homo sapiens		 126					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276519&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302241	378158185							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524827	COC1CN(C1)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1	InChI=1S/C18H16F4N6O2/c1-29-14-8-27(9-14)13-5-23-17(24-6-13)30-10-11-7-28(26-25-11)12-2-3-16(19)15(4-12)18(20,21)22/h2-7,14H,8-10H2,1H3	UEGHMZTWHCTBMW-UHFFFAOYSA-N	276520	2-((1-(3-(Trifluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 460::US10233173, Example 460	Retinoic acid receptor RXR-alpha	Homo sapiens		 726					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276520&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302202	378158186							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524828	Fc1c(cccc1C(F)(F)F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H8ClF4N5O/c15-8-4-20-13(21-5-8)25-7-9-6-24(23-22-9)11-3-1-2-10(12(11)16)14(17,18)19/h1-6H,7H2	MSFRGMPMHCMHCT-UHFFFAOYSA-N	276521	5-Chloro-2-[[1-[2-fluoro-3-(trifluoromethyl)phenyl]triazol-4-::US10071988, Example 461::US10233173, Example 461	Retinoic acid receptor RXR-alpha	Homo sapiens		 70.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276521&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309739	378158187							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524829	Cc1cc(OCc2cn(nn2)-c2ccc(F)c(C)c2)ncn1	InChI=1S/C15H14FN5O/c1-10-5-13(3-4-14(10)16)21-7-12(19-20-21)8-22-15-6-11(2)17-9-18-15/h3-7,9H,8H2,1-2H3	VEDUOOPXAMZQPE-UHFFFAOYSA-N	276522	4-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-6-methyl-::US10071988, Example 462::US10233173, Example 462	Retinoic acid receptor RXR-alpha	Homo sapiens		 3030					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276522&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309743	378158188							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524830	Cc1c(F)cccc1-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H11ClFN5O/c1-9-12(16)3-2-4-13(9)21-7-11(19-20-21)8-22-14-17-5-10(15)6-18-14/h2-7H,8H2,1H3	HLBLYFPHHIKZCY-UHFFFAOYSA-N	276523	5-Chloro-2-[[1-(3-fluoro-2-methyl-phenyl)triazol-4-::US10071988, Example 463::US10233173, Example 463	Retinoic acid receptor RXR-alpha	Homo sapiens		 647					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276523&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309742	378158189							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524831	Cc1cnc(OCc2cn(nn2)-c2cccc(F)c2C)nc1	InChI=1S/C15H14FN5O/c1-10-6-17-15(18-7-10)22-9-12-8-21(20-19-12)14-5-3-4-13(16)11(14)2/h3-8H,9H2,1-2H3	USGVQTHMIRKHBT-UHFFFAOYSA-N	276524	2-[[1-(3-Fluoro-2-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 464::US10233173, Example 464	Retinoic acid receptor RXR-alpha	Homo sapiens		 515					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276524&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309740	378158190							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524832	Cc1nc(OCc2cn(nn2)-c2cccc(F)c2C)ncc1F	InChI=1S/C15H13F2N5O/c1-9-12(16)4-3-5-14(9)22-7-11(20-21-22)8-23-15-18-6-13(17)10(2)19-15/h3-7H,8H2,1-2H3	SGGPDHKLZAABGF-UHFFFAOYSA-N	276525	5-Fluoro-2-[[1-(3-fluoro-2-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 465::US10233173, Example 465	Retinoic acid receptor RXR-alpha	Homo sapiens		 3720					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276525&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309741	378158191							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524833	Cc1c(F)cccc1-n1cc(COc2ncc(cn2)C(C)(C)O)nn1	InChI=1S/C17H18FN5O2/c1-11-14(18)5-4-6-15(11)23-9-13(21-22-23)10-25-16-19-7-12(8-20-16)17(2,3)24/h4-9,24H,10H2,1-3H3	FEVMAVZPYZRGHW-UHFFFAOYSA-N	276526	2-[2-[[1-(3-Fluoro-2-methyl-phenyl)triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 466::US10233173, Example 466	Retinoic acid receptor RXR-alpha	Homo sapiens		 7010					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276526&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309744	378158192							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524834	Cc1cnc(OCc2cn(nn2)-c2cccc(C)c2F)nc1	InChI=1S/C15H14FN5O/c1-10-6-17-15(18-7-10)22-9-12-8-21(20-19-12)13-5-3-4-11(2)14(13)16/h3-8H,9H2,1-2H3	WSIDGSOKTXLHFO-UHFFFAOYSA-N	276527	2-[[1-(2-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 467::US10233173, Example 467	Retinoic acid receptor RXR-alpha	Homo sapiens		 711					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276527&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309747	378158193							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524835	Cc1cccc(c1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H11ClFN5O/c1-9-3-2-4-12(13(9)16)21-7-11(19-20-21)8-22-14-17-5-10(15)6-18-14/h2-7H,8H2,1H3	FLXLBSXCTYNLCK-UHFFFAOYSA-N	276528	5-Chloro-2-[[1-(2-fluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 468::US10233173, Example 468	Retinoic acid receptor RXR-alpha	Homo sapiens		 1250					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276528&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309746	378158194							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524836	Cc1cccc(c1F)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H11F4N5O/c1-9-3-2-4-12(13(9)16)24-7-11(22-23-24)8-25-14-20-5-10(6-21-14)15(17,18)19/h2-7H,8H2,1H3	YZLPGNUTXHPTEN-UHFFFAOYSA-N	276529	2-[[1-(2-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-::US10071988, Example 469::US10233173, Example 469	Retinoic acid receptor RXR-alpha	Homo sapiens		 1058					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276529&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309745	378158195							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524837	Cc1cccc(c1F)-n1cc(COc2ncc(Cl)c(C)n2)nn1	InChI=1S/C15H13ClFN5O/c1-9-4-3-5-13(14(9)17)22-7-11(20-21-22)8-23-15-18-6-12(16)10(2)19-15/h3-7H,8H2,1-2H3	RDTBUYBUVSSEBG-UHFFFAOYSA-N	276530	5-Chloro-2-[[1-(2-fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 470::US10233173, Example 470	Retinoic acid receptor RXR-alpha	Homo sapiens		 659					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276530&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309748	378158196							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524838	Cc1cccc(c1F)-n1cc(COc2ncc(OC(F)F)cn2)nn1	InChI=1S/C15H12F3N5O2/c1-9-3-2-4-12(13(9)16)23-7-10(21-22-23)8-24-15-19-5-11(6-20-15)25-14(17)18/h2-7,14H,8H2,1H3	QMPYUPCGYIEIHW-UHFFFAOYSA-N	276531	5-(Difluoromethoxy)-2-[[1-(2-fluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 471::US10233173, Example 471	Retinoic acid receptor RXR-alpha	Homo sapiens		 1729					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276531&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309749	378158197							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524839	Cc1cc(ccc1F)-n1cc(COc2nccc(N)n2)nn1	InChI=1S/C14H13FN6O/c1-9-6-11(2-3-12(9)15)21-7-10(19-20-21)8-22-14-17-5-4-13(16)18-14/h2-7H,8H2,1H3,(H2,16,17,18)	PBFHWYVQPQHHBM-UHFFFAOYSA-N	276532	2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]pyrimidin-4-::US10071988, Example 472::US10233173, Example 472	Retinoic acid receptor RXR-alpha	Homo sapiens		 149					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276532&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309750	378158198							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524840	Cc1cc(ccc1F)-n1cc(COc2ncccn2)nn1	InChI=1S/C14H12FN5O/c1-10-7-12(3-4-13(10)15)20-8-11(18-19-20)9-21-14-16-5-2-6-17-14/h2-8H,9H2,1H3	VVINLBNYCPUYRP-UHFFFAOYSA-N	276533	2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 473::US10233173, Example 473	Retinoic acid receptor RXR-alpha	Homo sapiens		 72.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276533&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309383	378158199							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524841	Cc1cc(ccc1F)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H11F2N5O/c1-9-4-12(2-3-13(9)16)21-7-11(19-20-21)8-22-14-17-5-10(15)6-18-14/h2-7H,8H2,1H3	JMOAYVOBMBWNMX-UHFFFAOYSA-N	276534	5-Fluoro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 474::US10233173, Example 474	Retinoic acid receptor RXR-alpha	Homo sapiens		 22.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276534&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309443	378158200							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524842	COc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2)nc1	InChI=1S/C15H14FN5O2/c1-10-5-12(3-4-14(10)16)21-8-11(19-20-21)9-23-15-17-6-13(22-2)7-18-15/h3-8H,9H2,1-2H3	UBQWOGVNUZXGJA-UHFFFAOYSA-N	276535	2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 475::US10233173, Example 475	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276535&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309431	378158201							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524843	Cc1cc(ccc1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H11ClFN5O/c1-9-4-12(2-3-13(9)16)21-7-11(19-20-21)8-22-14-17-5-10(15)6-18-14/h2-7H,8H2,1H3	UOOXQHCSQXAAAC-UHFFFAOYSA-N	276536	5-Chloro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 476::US10233173, Example 476	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276536&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309432	378158202							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524844	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2)nc1	InChI=1S/C15H14FN5O/c1-10-6-17-15(18-7-10)22-9-12-8-21(20-19-12)13-3-4-14(16)11(2)5-13/h3-8H,9H2,1-2H3	XVXPBMJKCJQWIF-UHFFFAOYSA-N	276537	2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 477::US10233173, Example 477	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276537&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309441	378158203							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524845	CCc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2)nc1	InChI=1S/C16H16FN5O/c1-3-12-7-18-16(19-8-12)23-10-13-9-22(21-20-13)14-4-5-15(17)11(2)6-14/h4-9H,3,10H2,1-2H3	YJAJDLDVLWXMHC-UHFFFAOYSA-N	276538	5-Ethyl-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 478::US10233173, Example 478	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276538&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309430	378158204							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524846	COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(C)c2)n1	InChI=1S/C16H16FN5O2/c1-11-7-14(3-4-15(11)17)22-8-13(20-21-22)10-24-16-18-6-5-12(19-16)9-23-2/h3-8H,9-10H2,1-2H3	HABGRXANLFCZFV-UHFFFAOYSA-N	276539	2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 479::US10233173, Example 479	Retinoic acid receptor RXR-alpha	Homo sapiens		 36.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276539&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309751	378158205							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524847	Cc1cc(ccc1F)-n1cc(COc2ncc(C)c(C)n2)nn1	InChI=1S/C16H16FN5O/c1-10-6-14(4-5-15(10)17)22-8-13(20-21-22)9-23-16-18-7-11(2)12(3)19-16/h4-8H,9H2,1-3H3	RLECKJBCGVCNBU-UHFFFAOYSA-N	276540	2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4,5-dimethyl-::US10071988, Example 480::US10233173, Example 480	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276540&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309755	378158206							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524848	Cc1cc(ccc1F)-n1cc(COc2ncc(F)c(C)n2)nn1	InChI=1S/C15H13F2N5O/c1-9-5-12(3-4-13(9)16)22-7-11(20-21-22)8-23-15-18-6-14(17)10(2)19-15/h3-7H,8H2,1-2H3	KSUYLNWNPOJALW-UHFFFAOYSA-N	276541	5-Fluoro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 481::US10233173, Example 481	Retinoic acid receptor RXR-alpha	Homo sapiens		 2.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276541&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309753	378158207							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524849	Cc1cc(ccc1F)-n1cc(COc2ncc(Cl)c(C)n2)nn1	InChI=1S/C15H13ClFN5O/c1-9-5-12(3-4-14(9)17)22-7-11(20-21-22)8-23-15-18-6-13(16)10(2)19-15/h3-7H,8H2,1-2H3	HJZBNGPFWRHXIG-UHFFFAOYSA-N	276542	5-Chloro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 482::US10233173, Example 482	Retinoic acid receptor RXR-alpha	Homo sapiens		 1.000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276542&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309752	378158208							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524850	Cc1cc(ccc1F)-n1cc(COc2ncc(OCCF)cn2)nn1	InChI=1S/C16H15F2N5O2/c1-11-6-13(2-3-15(11)18)23-9-12(21-22-23)10-25-16-19-7-14(8-20-16)24-5-4-17/h2-3,6-9H,4-5,10H2,1H3	FCCWFFCEIFRDPC-UHFFFAOYSA-N	276543	5-(2-Fluoroethoxy)-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 483::US10233173, Example 483	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276543&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309754	378158209							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524851	Cc1ccc(F)c(c1)-n1cc(COc2ncc(C)cn2)nn1	InChI=1S/C15H14FN5O/c1-10-3-4-13(16)14(5-10)21-8-12(19-20-21)9-22-15-17-6-11(2)7-18-15/h3-8H,9H2,1-2H3	USRIHEPWNSJMMT-UHFFFAOYSA-N	276544	2-[[1-(2-Fluoro-5-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 484::US10233173, Example 484	Retinoic acid receptor RXR-alpha	Homo sapiens		 1000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276544&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309756	378158210							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524852	Cc1ccc(F)c(c1)-n1cc(COc2ncc(Cl)c(C)n2)nn1	InChI=1S/C15H13ClFN5O/c1-9-3-4-13(17)14(5-9)22-7-11(20-21-22)8-23-15-18-6-12(16)10(2)19-15/h3-7H,8H2,1-2H3	KCBPJDQAHWOPEY-UHFFFAOYSA-N	276545	5-Chloro-2-[[1-(2-fluoro-5-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 485::US10233173, Example 485	Retinoic acid receptor RXR-alpha	Homo sapiens		 1010					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276545&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309757	378158211							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524853	Cc1ccc(F)c(c1)-n1cc(COc2ncc(F)c(C)n2)nn1	InChI=1S/C15H13F2N5O/c1-9-3-4-12(16)14(5-9)22-7-11(20-21-22)8-23-15-18-6-13(17)10(2)19-15/h3-7H,8H2,1-2H3	UWXAGCPZQFWVLK-UHFFFAOYSA-N	276546	5-Fluoro-2-[[1-(2-fluoro-5-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 486::US10233173, Example 486	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276546&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309758	378158212							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524854	Cc1cc(F)ccc1-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H11F2N5O/c1-9-4-10(15)2-3-13(9)21-7-12(19-20-21)8-22-14-17-5-11(16)6-18-14/h2-7H,8H2,1H3	XTVXOFBAFNVSDJ-UHFFFAOYSA-N	276547	5-Fluoro-2-[[1-(4-fluoro-2-methyl-phenyl)triazol-4-::US10071988, Example 487::US10233173, Example 487	Retinoic acid receptor RXR-alpha	Homo sapiens		 16199					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276547&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309759	378158213							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524855	COc1cnc(OCc2cn(nn2)-c2ccc(F)cc2C)nc1	InChI=1S/C15H14FN5O2/c1-10-5-11(16)3-4-14(10)21-8-12(19-20-21)9-23-15-17-6-13(22-2)7-18-15/h3-8H,9H2,1-2H3	BLOKUKDWVMHARP-UHFFFAOYSA-N	276548	2-[[1-(4-Fluoro-2-methyl-phenyl)triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 488::US10233173, Example 488	Retinoic acid receptor RXR-alpha	Homo sapiens		 2650					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276548&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309760	378158214							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524856	Cc1cc(F)ccc1-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H11ClFN5O/c1-9-4-11(16)2-3-13(9)21-7-12(19-20-21)8-22-14-17-5-10(15)6-18-14/h2-7H,8H2,1H3	KNZNZJKGNLMDEJ-UHFFFAOYSA-N	276549	5-Chloro-2-[[1-(4-fluoro-2-methyl-phenyl)triazol-4-::US10071988, Example 489::US10233173, Example 489	Retinoic acid receptor RXR-alpha	Homo sapiens		 4420					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276549&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309761	378158215							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524857	Cc1cnc(OCc2cn(nn2)-c2ccc(F)cc2C)nc1	InChI=1S/C15H14FN5O/c1-10-6-17-15(18-7-10)22-9-13-8-21(20-19-13)14-4-3-12(16)5-11(14)2/h3-8H,9H2,1-2H3	RWXQDOOQFJCEGO-UHFFFAOYSA-N	276550	2-[[1-(4-Fluoro-2-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 490::US10233173, Example 490	Retinoic acid receptor RXR-alpha	Homo sapiens		 2440					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276550&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309762	378158216							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524858	CCc1cnc(OCc2cn(nn2)-c2ccc(F)cc2C)nc1	InChI=1S/C16H16FN5O/c1-3-12-7-18-16(19-8-12)23-10-14-9-22(21-20-14)15-5-4-13(17)6-11(15)2/h4-9H,3,10H2,1-2H3	WGDIXCSOVBFWMZ-UHFFFAOYSA-N	276551	5-Ethyl-2-[[1-(4-fluoro-2-methyl-phenyl)triazol-4-::US10071988, Example 491::US10233173, Example 491	Retinoic acid receptor RXR-alpha	Homo sapiens		 1170					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276551&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309763	378158217							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524859	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(F)cn2)nn1	InChI=1S/C14H9F4N5O2/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-11(16)12(3-10)25-13(17)18/h1-6,13H,7H2	MWMIHLVSXJUGMS-UHFFFAOYSA-N	276552	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 492::US10233173, Example 492	Retinoic acid receptor RXR-alpha	Homo sapiens		 26.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276552&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309764	378158218							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524860	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)ncc1F	InChI=1S/C15H11F4N5O2/c1-8-12(17)5-20-15(21-8)25-7-9-6-24(23-22-9)10-2-3-11(16)13(4-10)26-14(18)19/h2-6,14H,7H2,1H3	MSIBJORVRYZYOT-UHFFFAOYSA-N	276553	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 493::US10233173, Example 493	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276553&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309765	378158219							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524861	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(Br)cn2)nn1	InChI=1S/C14H9BrF3N5O2/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-11(16)12(3-10)25-13(17)18/h1-6,13H,7H2	ZVIKWIHFCXUFHA-UHFFFAOYSA-N	276554	5-Bromo-2-[[1-[3-(difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 494::US10233173, Example 494	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276554&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309766	378158220							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524862	CCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C16H14F3N5O2/c1-2-10-5-6-20-16(21-10)25-9-11-8-24(23-22-11)12-3-4-13(17)14(7-12)26-15(18)19/h3-8,15H,2,9H2,1H3	PKXHVBKKARGUAN-UHFFFAOYSA-N	276555	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 495::US10233173, Example 495	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276555&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309767	378158221							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524863	CC(C)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C17H16F3N5O2/c1-10(2)14-5-6-21-17(22-14)26-9-11-8-25(24-23-11)12-3-4-13(18)15(7-12)27-16(19)20/h3-8,10,16H,9H2,1-2H3	PEKUYYVJBUZFGF-UHFFFAOYSA-N	276556	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 496::US10233173, Example 496	Retinoic acid receptor RXR-alpha	Homo sapiens		 114					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276556&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309768	378158222							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524864	COc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C15H12F3N5O3/c1-24-13-4-5-19-15(20-13)25-8-9-7-23(22-21-9)10-2-3-11(16)12(6-10)26-14(17)18/h2-7,14H,8H2,1H3	CNYLBHRHDRWZJA-UHFFFAOYSA-N	276557	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 497::US10233173, Example 497	Retinoic acid receptor RXR-alpha	Homo sapiens		 28.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276557&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309769	378158223							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524865	OCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C15H12F3N5O3/c16-12-2-1-11(5-13(12)26-14(17)18)23-6-10(21-22-23)8-25-15-19-4-3-9(7-24)20-15/h1-6,14,24H,7-8H2	FKKNIVZKCJQRQA-UHFFFAOYSA-N	276558	US10071988, Example 498::US10233173, Example 498::[2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 19.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276558&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309785	378158224							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524866	COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C16H14F3N5O3/c1-25-8-10-4-5-20-16(21-10)26-9-11-7-24(23-22-11)12-2-3-13(17)14(6-12)27-15(18)19/h2-7,15H,8-9H2,1H3	BZQOGTTUTCCEIL-UHFFFAOYSA-N	276559	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 499::US10233173, Example 499	Retinoic acid receptor RXR-alpha	Homo sapiens		 16.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276559&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309770	378158225							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524867	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)nc1	InChI=1S/C17H16F3N5O3/c1-17(2,26)10-6-21-16(22-7-10)27-9-11-8-25(24-23-11)12-3-4-13(18)14(5-12)28-15(19)20/h3-8,15,26H,9H2,1-2H3	HTKDZSSUNSIGLN-UHFFFAOYSA-N	276560	2-[2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 500::US10233173, Example 500	Retinoic acid receptor RXR-alpha	Homo sapiens		 68.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276560&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309771	378158226							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524868	Nc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C14H11F3N6O2/c15-10-2-1-9(5-11(10)25-13(16)17)23-6-8(21-22-23)7-24-14-19-4-3-12(18)20-14/h1-6,13H,7H2,(H2,18,19,20)	FXUCNQGXTVLPEZ-UHFFFAOYSA-N	276561	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 501::US10233173, Example 501	Retinoic acid receptor RXR-alpha	Homo sapiens		 52.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276561&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309772	378158227							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524869	Nc1cnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)nc1	InChI=1S/C14H11F3N6O2/c15-11-2-1-10(3-12(11)25-13(16)17)23-6-9(21-22-23)7-24-14-19-4-8(18)5-20-14/h1-6,13H,7,18H2	HYUMSEUSFFWIDI-UHFFFAOYSA-N	276562	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 502::US10233173, Example 502	Retinoic acid receptor RXR-alpha	Homo sapiens		 136					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276562&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309773	378158228							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524870	CNc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C15H13F3N6O2/c1-19-13-4-5-20-15(21-13)25-8-9-7-24(23-22-9)10-2-3-11(16)12(6-10)26-14(17)18/h2-7,14H,8H2,1H3,(H,19,20,21)	DXOYYFQRTPZDDN-UHFFFAOYSA-N	276563	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 503::US10233173, Example 503	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276563&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309786	378158229							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524871	CCNc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C16H15F3N6O2/c1-2-20-14-5-6-21-16(22-14)26-9-10-8-25(24-23-10)11-3-4-12(17)13(7-11)27-15(18)19/h3-8,15H,2,9H2,1H3,(H,20,21,22)	NHFWVSLDSZYAJJ-UHFFFAOYSA-N	276564	2-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 504::US10233173, Example 504	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276564&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302438	378158230							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524872	CN(C)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C16H15F3N6O2/c1-24(2)14-5-6-20-16(21-14)26-9-10-8-25(23-22-10)11-3-4-12(17)13(7-11)27-15(18)19/h3-8,15H,9H2,1-2H3	HBWGMTGJMCFXRR-UHFFFAOYSA-N	276565	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N,N-::US10071988, Example 505::US10233173, Example 505	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276565&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309776	378158231							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524873	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)-c2ccccc2)nn1	InChI=1S/C20H14F3N5O2/c21-16-7-6-15(10-18(16)30-19(22)23)28-11-14(26-27-28)12-29-20-24-9-8-17(25-20)13-4-2-1-3-5-13/h1-11,19H,12H2	JYYJWGXXCHEHDE-UHFFFAOYSA-N	276566	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 506::US10233173, Example 506	Retinoic acid receptor RXR-alpha	Homo sapiens		 9750					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276566&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309774	378158232							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524874	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CC(F)C2)nn1	InChI=1S/C17H14F4N6O2/c18-10-6-26(7-10)13-4-22-17(23-5-13)28-9-11-8-27(25-24-11)12-1-2-14(19)15(3-12)29-16(20)21/h1-5,8,10,16H,6-7,9H2	HUJSBZTVIDXCCT-UHFFFAOYSA-N	276567	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-(3-::US10071988, Example 507::US10233173, Example 507	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276567&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309787	378158233							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524875	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CC(F)(F)C2)nn1	InChI=1S/C17H13F5N6O2/c18-13-2-1-11(3-14(13)30-15(19)20)28-6-10(25-26-28)7-29-16-23-4-12(5-24-16)27-8-17(21,22)9-27/h1-6,15H,7-9H2	PRGJHGOIUONFPF-UHFFFAOYSA-N	276568	5-(3,3-Difluoroazetidin-1-yl)-2-[[1-[3-(difluoromethoxy)-4-fluoro-::US10071988, Example 508::US10233173, Example 508	Retinoic acid receptor RXR-alpha	Homo sapiens		 19.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276568&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309777	378158234							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524876	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CCC2)nn1	InChI=1S/C17H15F3N6O2/c18-13-3-2-12(8-14(13)28-16(19)20)26-9-11(23-24-26)10-27-17-21-5-4-15(22-17)25-6-1-7-25/h2-5,8-9,16H,1,6-7,10H2	ACEUPHBZNSKHPO-UHFFFAOYSA-N	276569	4-(Azetidin-1-yl)-2-[[1-[3-(difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 509::US10233173, Example 509	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276569&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309778	378158235							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524877	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CC(F)C2)nn1	InChI=1S/C17H14F4N6O2/c18-10-6-26(7-10)15-3-4-22-17(23-15)28-9-11-8-27(25-24-11)12-1-2-13(19)14(5-12)29-16(20)21/h1-5,8,10,16H,6-7,9H2	KVKDWYWBOKOSHV-UHFFFAOYSA-N	276570	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-(3-::US10071988, Example 510::US10233173, Example 510	Retinoic acid receptor RXR-alpha	Homo sapiens		 25.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276570&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309783	378158236							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524878	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CC(F)(F)C2)nn1	InChI=1S/C17H13F5N6O2/c18-12-2-1-11(5-13(12)30-15(19)20)28-6-10(25-26-28)7-29-16-23-4-3-14(24-16)27-8-17(21,22)9-27/h1-6,15H,7-9H2	RCUFTDBDPBZJIX-UHFFFAOYSA-N	276571	4-(3,3-Difluoroazetidin-1-yl)-2-[[1-[3-(difluoromethoxy)-4-fluoro-::US10071988, Example 511::US10233173, Example 511	Retinoic acid receptor RXR-alpha	Homo sapiens		 41.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276571&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309779	378158237							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524879	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)N2CC[C@@H](F)C2)nn1	InChI=1S/C18H16F4N6O2/c19-11-4-6-27(8-11)16-3-5-23-18(24-16)29-10-12-9-28(26-25-12)13-1-2-14(20)15(7-13)30-17(21)22/h1-3,5,7,9,11,17H,4,6,8,10H2/t11-/m1/s1	GGSFCMKSWHYTAP-LLVKDONJSA-N	276572	(R)-2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-::US10071988, Example 512::US10233173, Example 512	Retinoic acid receptor RXR-alpha	Homo sapiens		 308					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276572&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309780	378158238							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524880	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)ncc1Cl	InChI=1S/C15H11ClF3N5O2/c1-8-11(16)5-20-15(21-8)25-7-9-6-24(23-22-9)10-2-3-12(17)13(4-10)26-14(18)19/h2-6,14H,7H2,1H3	CIPOVAMGNKCGIS-UHFFFAOYSA-N	276573	5-Chloro-2-[[1-[3-(difluoromethoxy)-4-fluoro-phenyl]triazol-4-::US10071988, Example 513::US10233173, Example 513	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276573&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309781	378158239							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524881	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)nc1N	InChI=1S/C15H13F3N6O2/c1-8-5-20-15(21-13(8)19)25-7-9-6-24(23-22-9)10-2-3-11(16)12(4-10)26-14(17)18/h2-6,14H,7H2,1H3,(H2,19,20,21)	IZMFBCFSTXMUTM-UHFFFAOYSA-N	276574	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 514::US10233173, Example 514	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276574&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309782	378158240							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524882	CNc1nc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)ncc1C	InChI=1S/C16H15F3N6O2/c1-9-6-21-16(22-14(9)20-2)26-8-10-7-25(24-23-10)11-3-4-12(17)13(5-11)27-15(18)19/h3-7,15H,8H2,1-2H3,(H,20,21,22)	QMMVOLBVIJNMFI-UHFFFAOYSA-N	276575	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N,5-::US10071988, Example 515::US10233173, Example 515	Retinoic acid receptor RXR-alpha	Homo sapiens		 99.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276575&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309788	378158241							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524883	CN(C)c1nc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)ncc1C	InChI=1S/C17H17F3N6O2/c1-10-7-21-17(22-15(10)25(2)3)27-9-11-8-26(24-23-11)12-4-5-13(18)14(6-12)28-16(19)20/h4-8,16H,9H2,1-3H3	SHMUNFWXBLEBIV-UHFFFAOYSA-N	276576	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-::US10071988, Example 516::US10233173, Example 516	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276576&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309792	378158242							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524884	FC(F)CNc1nc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)ncc1F	InChI=1S/C16H12F6N6O2/c17-10-2-1-9(3-12(10)30-15(21)22)28-6-8(26-27-28)7-29-16-24-4-11(18)14(25-16)23-5-13(19)20/h1-4,6,13,15H,5,7H2,(H,23,24,25)	VRESRGBIMTUYKE-UHFFFAOYSA-N	276577	N-(2,2-Difluoroethyl)-2-[[1-[3-(difluoromethoxy)-4-fluoro-::US10071988, Example 517::US10233173, Example 517	Retinoic acid receptor RXR-alpha	Homo sapiens		 912					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276577&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309784	378158243							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524885	CNc1nc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)ncc1F	InChI=1S/C15H12F4N6O2/c1-20-13-11(17)5-21-15(22-13)26-7-8-6-25(24-23-8)9-2-3-10(16)12(4-9)27-14(18)19/h2-6,14H,7H2,1H3,(H,20,21,22)	DQOMPHGTVDBHJA-UHFFFAOYSA-N	276578	2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 518::US10233173, Example 518	Retinoic acid receptor RXR-alpha	Homo sapiens		 92.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276578&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309795	378158244							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524886	FC(F)Oc1cc(ccc1F)-n1cc(COc2ncc(F)c(NC3CC3)n2)nn1	InChI=1S/C17H14F4N6O2/c18-12-4-3-11(5-14(12)29-16(20)21)27-7-10(25-26-27)8-28-17-22-6-13(19)15(24-17)23-9-1-2-9/h3-7,9,16H,1-2,8H2,(H,22,23,24)	ZUNAKNIJLCRPLZ-UHFFFAOYSA-N	276579	N-Cyclopropyl-2-((1-(3-(difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-::US10071988, Example 519::US10233173, Example 519	Retinoic acid receptor RXR-alpha	Homo sapiens		 204					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276579&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302233	378158245							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524887	CNCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C16H15F3N6O2/c1-20-7-10-4-5-21-16(22-10)26-9-11-8-25(24-23-11)12-2-3-13(17)14(6-12)27-15(18)19/h2-6,8,15,20H,7,9H2,1H3	NLBXPYGCDJCVKR-UHFFFAOYSA-N	276580	1-(2-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 520::US10233173, Example 520	Retinoic acid receptor RXR-alpha	Homo sapiens		 672					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276580&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309789	378158246							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524888	Cc1cnc(OCc2cn(nn2)-c2ccc(C)c(OC(F)F)c2)nc1N	InChI=1S/C16H16F2N6O2/c1-9-3-4-12(5-13(9)26-15(17)18)24-7-11(22-23-24)8-25-16-20-6-10(2)14(19)21-16/h3-7,15H,8H2,1-2H3,(H2,19,20,21)	WBZBOFDAFFZLFQ-UHFFFAOYSA-N	276581	2-[[1-[3-(Difluoromethoxy)-4-methyl-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 521::US10233173, Example 521	Retinoic acid receptor RXR-alpha	Homo sapiens		 21.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276581&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309790	378158247							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524889	CC(=O)c1cnc(OCc2cn(nn2)-c2ccc(C)c(OC(F)F)c2)nc1	InChI=1S/C17H15F2N5O3/c1-10-3-4-14(5-15(10)27-16(18)19)24-8-13(22-23-24)9-26-17-20-6-12(7-21-17)11(2)25/h3-8,16H,9H2,1-2H3	YOHSOKUXLWWCLC-UHFFFAOYSA-N	276582	1-[2-[[1-[3-(Difluoromethoxy)-4-methyl-phenyl]triazol-4-::US10071988, Example 522::US10233173, Example 522	Retinoic acid receptor RXR-alpha	Homo sapiens		 93.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276582&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309793	378158248							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524890	Cc1ccnc(OCc2cn(nn2)-c2ccc(C)c(OC(F)F)c2)n1	InChI=1S/C16H15F2N5O2/c1-10-3-4-13(7-14(10)25-15(17)18)23-8-12(21-22-23)9-24-16-19-6-5-11(2)20-16/h3-8,15H,9H2,1-2H3	PHIONAMCVVPDDR-UHFFFAOYSA-N	276583	2-[[1-[3-(Difluoromethoxy)-4-methyl-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 523::US10233173, Example 523	Retinoic acid receptor RXR-alpha	Homo sapiens		 114					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276583&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309794	378158249							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524891	Cc1cnc(OCc2cn(nn2)-c2ccc(C)c(OC(F)F)c2)nc1	InChI=1S/C16H15F2N5O2/c1-10-6-19-16(20-7-10)24-9-12-8-23(22-21-12)13-4-3-11(2)14(5-13)25-15(17)18/h3-8,15H,9H2,1-2H3	ALZRKGLSAJHCNF-UHFFFAOYSA-N	276584	2-[[1-[3-(Difluoromethoxy)-4-methyl-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 524::US10233173, Example 524	Retinoic acid receptor RXR-alpha	Homo sapiens		 28.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276584&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309791	378158250							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524892	Cc1ccc(cc1OC(F)F)-n1cc(COc2ncc(Br)cn2)nn1	InChI=1S/C15H12BrF2N5O2/c1-9-2-3-12(4-13(9)25-14(17)18)23-7-11(21-22-23)8-24-15-19-5-10(16)6-20-15/h2-7,14H,8H2,1H3	YXENUGCAHCEBGR-UHFFFAOYSA-N	276585	5-Bromo-2-[[1-[3-(difluoromethoxy)-4-methyl-phenyl]triazol-4-::US10071988, Example 525::US10233173, Example 525	Retinoic acid receptor RXR-alpha	Homo sapiens		 40.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276585&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309803	378158251							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524893	Cc1ccc(cc1OC(F)F)-n1cc(COc2ncc(cn2)C(C)(C)O)nn1	InChI=1S/C18H19F2N5O3/c1-11-4-5-14(6-15(11)28-16(19)20)25-9-13(23-24-25)10-27-17-21-7-12(8-22-17)18(2,3)26/h4-9,16,26H,10H2,1-3H3	HZZLVWYHNKRXPE-UHFFFAOYSA-N	276586	2-[2-[[1-[3-(Difluoromethoxy)-4-methyl-phenyl]triazol-4-::US10071988, Example 526::US10233173, Example 526	Retinoic acid receptor RXR-alpha	Homo sapiens		 425					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276586&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309804	378158252							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524894	COCc1ccnc(OCc2cn(nn2)-c2ccc(C)c(OC(F)F)c2)n1	InChI=1S/C17H17F2N5O3/c1-11-3-4-14(7-15(11)27-16(18)19)24-8-13(22-23-24)10-26-17-20-6-5-12(21-17)9-25-2/h3-8,16H,9-10H2,1-2H3	JPHWGRKSYQQATI-UHFFFAOYSA-N	276587	2-[[1-[3-(Difluoromethoxy)-4-methyl-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 527::US10233173, Example 527	Retinoic acid receptor RXR-alpha	Homo sapiens		 132					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276587&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309796	378158253							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524895	Cc1c(COc2ncc(C)c(C)n2)nnn1-c1cccc(c1)C(F)F	InChI=1S/C17H17F2N5O/c1-10-8-20-17(21-11(10)2)25-9-15-12(3)24(23-22-15)14-6-4-5-13(7-14)16(18)19/h4-8,16H,9H2,1-3H3	RDEGVPYIEAHVRQ-UHFFFAOYSA-N	276588	2-[[1-[3-(Difluoromethyl)phenyl]-5-methyl-triazol-4-yl]methoxy]-4,5-::US10071988, Example 528::US10233173, Example 528	Retinoic acid receptor RXR-alpha	Homo sapiens		 752					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276588&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309797	378158254							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524896	Cc1c(COc2ncc(Cl)cn2)nnn1-c1cccc(c1)C(F)F	InChI=1S/C15H12ClF2N5O/c1-9-13(8-24-15-19-6-11(16)7-20-15)21-22-23(9)12-4-2-3-10(5-12)14(17)18/h2-7,14H,8H2,1H3	JXUMLOFGOMFLMF-UHFFFAOYSA-N	276589	5-Chloro-2-[[1-[3-(difluoromethyl)phenyl]-5-methyl-triazol-4-::US10071988, Example 529::US10233173, Example 529	Retinoic acid receptor RXR-alpha	Homo sapiens		 1320					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276589&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309798	378158255							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524897	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)nc1	InChI=1S/C16H14ClF2N5O/c1-10-6-20-15(21-7-10)25-9-11-8-24(23-22-11)12-3-4-14(17)13(5-12)16(2,18)19/h3-8H,9H2,1-2H3	AAGJRHLUNFHKER-UHFFFAOYSA-N	276590	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 530::US10233173, Example 530	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276590&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309799	378158256							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524898	Cc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)n1	InChI=1S/C16H14ClF2N5O/c1-10-5-6-20-15(21-10)25-9-11-8-24(23-22-11)12-3-4-14(17)13(7-12)16(2,18)19/h3-8H,9H2,1-2H3	SWHBXDBUGWAGRB-UHFFFAOYSA-N	276591	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 531::US10233173, Example 531	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276591&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309800	378158257							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524899	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)nc1	InChI=1S/C18H18ClF2N5O2/c1-17(2,27)11-7-22-16(23-8-11)28-10-12-9-26(25-24-12)13-4-5-15(19)14(6-13)18(3,20)21/h4-9,27H,10H2,1-3H3	ROGYDEXUQSBMGK-UHFFFAOYSA-N	276592	2-[2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 532::US10233173, Example 532	Retinoic acid receptor RXR-alpha	Homo sapiens		 81.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276592&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309801	378158258							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524900	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2ncc(CO)cn2)nn1	InChI=1S/C16H14ClF2N5O2/c1-16(18,19)13-4-12(2-3-14(13)17)24-7-11(22-23-24)9-26-15-20-5-10(8-25)6-21-15/h2-7,25H,8-9H2,1H3	FXVOYYGQIJUVBP-UHFFFAOYSA-N	276593	US10071988, Example 533::US10233173, Example 533::[2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276593&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309802	378158259							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524901	COCc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)n1	InChI=1S/C17H16ClF2N5O2/c1-17(19,20)14-7-13(3-4-15(14)18)25-8-12(23-24-25)10-27-16-21-6-5-11(22-16)9-26-2/h3-8H,9-10H2,1-2H3	GYOALVPXYAXJIT-UHFFFAOYSA-N	276594	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 534::US10233173, Example 534	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276594&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309806	378158260							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524902	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2ncc(cn2)C(F)F)nn1	InChI=1S/C16H12ClF4N5O/c1-16(20,21)12-4-11(2-3-13(12)17)26-7-10(24-25-26)8-27-15-22-5-9(6-23-15)14(18)19/h2-7,14H,8H2,1H3	SCHOYBYKAYKJLP-UHFFFAOYSA-N	276595	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 535::US10233173, Example 535	Retinoic acid receptor RXR-alpha	Homo sapiens		 9.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276595&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309805	378158261							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524903	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2nccc(n2)C(F)F)nn1	InChI=1S/C16H12ClF4N5O/c1-16(20,21)11-6-10(2-3-12(11)17)26-7-9(24-25-26)8-27-15-22-5-4-13(23-15)14(18)19/h2-7,14H,8H2,1H3	YHXCAKWCRNIABJ-UHFFFAOYSA-N	276596	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 536::US10233173, Example 536	Retinoic acid receptor RXR-alpha	Homo sapiens		 67.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276596&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309807	378158262							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524904	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C16H11ClF5N5O/c1-15(18,19)12-4-11(2-3-13(12)17)27-7-10(25-26-27)8-28-14-23-5-9(6-24-14)16(20,21)22/h2-7H,8H2,1H3	AIQNIVLEFCDLOO-UHFFFAOYSA-N	276597	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 537::US10233173, Example 537	Retinoic acid receptor RXR-alpha	Homo sapiens		 16.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276597&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309808	378158263							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524905	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2nccc(n2)C(F)(F)F)nn1	InChI=1S/C16H11ClF5N5O/c1-15(18,19)11-6-10(2-3-12(11)17)27-7-9(25-26-27)8-28-14-23-5-4-13(24-14)16(20,21)22/h2-7H,8H2,1H3	UXSXBJNQAFFLMH-UHFFFAOYSA-N	276598	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 538::US10233173, Example 538	Retinoic acid receptor RXR-alpha	Homo sapiens		 318					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276598&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309811	378158264							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524906	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2ncc(cn2)C(C)(O)C(F)(F)F)nn1	InChI=1S/C18H15ClF5N5O2/c1-16(30,18(22,23)24)10-6-25-15(26-7-10)31-9-11-8-29(28-27-11)12-3-4-14(19)13(5-12)17(2,20)21/h3-8,30H,9H2,1-2H3	QFVZIWAWMKIXHA-UHFFFAOYSA-N	276599	(R/S)-2-[2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 539::US10233173, Example 539	Retinoic acid receptor RXR-alpha	Homo sapiens		 450					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276599&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309813	378158265							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524907	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2nccc(CO)n2)nn1	InChI=1S/C16H14ClF2N5O2/c1-16(18,19)13-6-12(2-3-14(13)17)24-7-11(22-23-24)9-26-15-20-5-4-10(8-25)21-15/h2-7,25H,8-9H2,1H3	ZTLFVMSXLOLVQF-UHFFFAOYSA-N	276600	US10071988, Example 540::US10233173, Example 540::[2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 19.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276600&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309809	378158266							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524908	COc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)n1	InChI=1S/C16H14ClF2N5O2/c1-16(18,19)12-7-11(3-4-13(12)17)24-8-10(22-23-24)9-26-15-20-6-5-14(21-15)25-2/h3-8H,9H2,1-2H3	WRKMTVPUKREOEY-UHFFFAOYSA-N	276601	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 541::US10233173, Example 541	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276601&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309810	378158267							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524909	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2ncc(OC(F)F)cn2)nn1	InChI=1S/C16H12ClF4N5O2/c1-16(20,21)12-4-10(2-3-13(12)17)26-7-9(24-25-26)8-27-15-22-5-11(6-23-15)28-14(18)19/h2-7,14H,8H2,1H3	OYFKHOUOZDFEIF-UHFFFAOYSA-N	276602	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 542::US10233173, Example 542	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276602&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309812	378158268							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524910	Cc1nc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)ncc1Cl	InChI=1S/C16H13Cl2F2N5O/c1-9-14(18)6-21-15(22-9)26-8-10-7-25(24-23-10)11-3-4-13(17)12(5-11)16(2,19)20/h3-7H,8H2,1-2H3	SAZWVXBHDXTTOA-UHFFFAOYSA-N	276603	5-Chloro-2-[[1-[4-chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 543::US10233173, Example 543	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276603&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309815	378158269							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524911	Cc1nc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)ncc1F	InChI=1S/C16H13ClF3N5O/c1-9-14(18)6-21-15(22-9)26-8-10-7-25(24-23-10)11-3-4-13(17)12(5-11)16(2,19)20/h3-7H,8H2,1-2H3	AXSCBNILWSGNQN-UHFFFAOYSA-N	276604	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 544::US10233173, Example 544	Retinoic acid receptor RXR-alpha	Homo sapiens		 15.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276604&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309817	378158270							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524912	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)nc1C	InChI=1S/C17H16ClF2N5O/c1-10-7-21-16(22-11(10)2)26-9-12-8-25(24-23-12)13-4-5-15(18)14(6-13)17(3,19)20/h4-8H,9H2,1-3H3	BLRWUCNCAIAODI-UHFFFAOYSA-N	276605	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4,5-::US10071988, Example 545::US10233173, Example 545	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276605&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309814	378158271							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524913	Cc1cc(C)nc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)n1	InChI=1S/C17H16ClF2N5O/c1-10-6-11(2)22-16(21-10)26-9-12-8-25(24-23-12)13-4-5-15(18)14(7-13)17(3,19)20/h4-8H,9H2,1-3H3	SOCALSARJOFIGL-UHFFFAOYSA-N	276606	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4,6-::US10071988, Example 546::US10233173, Example 546	Retinoic acid receptor RXR-alpha	Homo sapiens		 24.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276606&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309816	378158272							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524914	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2nccc(N)n2)nn1	InChI=1S/C15H13ClF2N6O/c1-15(17,18)11-6-10(2-3-12(11)16)24-7-9(22-23-24)8-25-14-20-5-4-13(19)21-14/h2-7H,8H2,1H3,(H2,19,20,21)	VOARJXHXGXXLOK-UHFFFAOYSA-N	276607	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 547::US10233173, Example 547	Retinoic acid receptor RXR-alpha	Homo sapiens		 33.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276607&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302307	378158273							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524915	CNc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)n1	InChI=1S/C16H15ClF2N6O/c1-16(18,19)12-7-11(3-4-13(12)17)25-8-10(23-24-25)9-26-15-21-6-5-14(20-2)22-15/h3-8H,9H2,1-2H3,(H,20,21,22)	JOCCIICDGFRXJP-UHFFFAOYSA-N	276608	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 548::US10233173, Example 548	Retinoic acid receptor RXR-alpha	Homo sapiens		 55.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276608&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309818	378158274							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524916	CNc1nc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)ncc1F	InChI=1S/C16H14ClF3N6O/c1-16(19,20)11-5-10(3-4-12(11)17)26-7-9(24-25-26)8-27-15-22-6-13(18)14(21-2)23-15/h3-7H,8H2,1-2H3,(H,21,22,23)	MQYNLHXGWAGKFK-UHFFFAOYSA-N	276609	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 549::US10233173, Example 549	Retinoic acid receptor RXR-alpha	Homo sapiens		 94.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276609&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309819	378158275							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524917	CC(=O)c1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)nc1	InChI=1S/C17H14ClF2N5O2/c1-10(26)11-6-21-16(22-7-11)27-9-12-8-25(24-23-12)13-3-4-15(18)14(5-13)17(2,19)20/h3-8H,9H2,1-2H3	HYZSDJJKDDEBRH-UHFFFAOYSA-N	276610	1-[2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 550::US10233173, Example 550	Retinoic acid receptor RXR-alpha	Homo sapiens		 16.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276610&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309820	378158276							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524918	CC(O)c1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(C)(F)F)nc1	InChI=1S/C17H16ClF2N5O2/c1-10(26)11-6-21-16(22-7-11)27-9-12-8-25(24-23-12)13-3-4-15(18)14(5-13)17(2,19)20/h3-8,10,26H,9H2,1-2H3	HNYWSFRUDMHCJT-UHFFFAOYSA-N	276611	(R/S)-1-[2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-::US10071988, Example 551::US10233173, Example 551	Retinoic acid receptor RXR-alpha	Homo sapiens		 14.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276611&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309821	378158277							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524919	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C18H16ClF2N5O/c1-18(20,21)15-6-14(4-5-16(15)19)26-9-13(24-25-26)10-27-17-22-7-12(8-23-17)11-2-3-11/h4-9,11H,2-3,10H2,1H3	ABZOGMJOEZNBIR-UHFFFAOYSA-N	276612	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 552::US10233173, Example 552	Retinoic acid receptor RXR-alpha	Homo sapiens		 86.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276612&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309822	378158278							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524920	CC(F)(F)c1cc(ccc1Cl)-n1cc(COc2nccc(n2)N2CCCC2)nn1	InChI=1S/C19H19ClF2N6O/c1-19(21,22)15-10-14(4-5-16(15)20)28-11-13(25-26-28)12-29-18-23-7-6-17(24-18)27-8-2-3-9-27/h4-7,10-11H,2-3,8-9,12H2,1H3	XQHJKFUMKCVZTG-UHFFFAOYSA-N	276613	2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 553::US10233173, Example 553	Retinoic acid receptor RXR-alpha	Homo sapiens		 43.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276613&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309823	378158279							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524921	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ccccn2)nn1	InChI=1S/C16H13F3N4O/c1-16(18,19)13-8-12(5-6-14(13)17)23-9-11(21-22-23)10-24-15-4-2-3-7-20-15/h2-9H,10H2,1H3	ZHGLSMYFHJHGFL-UHFFFAOYSA-N	276614	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 554::US10233173, Example 554	Retinoic acid receptor RXR-alpha	Homo sapiens		 1640					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276614&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309824	378158280							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524922	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncccc2F)nn1	InChI=1S/C16H12F4N4O/c1-16(19,20)12-7-11(4-5-13(12)17)24-8-10(22-23-24)9-25-15-14(18)3-2-6-21-15/h2-8H,9H2,1H3	XCQYEJMNJHRUPW-UHFFFAOYSA-N	276615	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-3-::US10071988, Example 555::US10233173, Example 555	Retinoic acid receptor RXR-alpha	Homo sapiens		 265					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276615&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309825	378158281							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524923	Cc1cccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)n1	InChI=1S/C17H15F3N4O/c1-11-4-3-5-16(21-11)25-10-12-9-24(23-22-12)13-6-7-15(18)14(8-13)17(2,19)20/h3-9H,10H2,1-2H3	ZKNAPYUAWJYOGP-UHFFFAOYSA-N	276616	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-6-::US10071988, Example 556::US10233173, Example 556	Retinoic acid receptor RXR-alpha	Homo sapiens		 98.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276616&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309826	378158282							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524924	Cc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)c1	InChI=1S/C17H15F3N4O/c1-11-5-6-21-16(7-11)25-10-12-9-24(23-22-12)13-3-4-15(18)14(8-13)17(2,19)20/h3-9H,10H2,1-2H3	OQLCIVJZDQEQSL-UHFFFAOYSA-N	276617	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 557::US10233173, Example 557	Retinoic acid receptor RXR-alpha	Homo sapiens		 246					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276617&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309827	378158283							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524925	Cc1ccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C17H15F3N4O/c1-11-3-6-16(21-8-11)25-10-12-9-24(23-22-12)13-4-5-15(18)14(7-13)17(2,19)20/h3-9H,10H2,1-2H3	LMWHZFUFUYWLGG-UHFFFAOYSA-N	276618	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 558::US10233173, Example 558	Retinoic acid receptor RXR-alpha	Homo sapiens		 125					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276618&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309828	378158284							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524926	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ccc(cn2)C(F)(F)F)nn1	InChI=1S/C17H12F6N4O/c1-16(19,20)13-6-12(3-4-14(13)18)27-8-11(25-26-27)9-28-15-5-2-10(7-24-15)17(21,22)23/h2-8H,9H2,1H3	SCSZXNAQKYLEOJ-UHFFFAOYSA-N	276619	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 559::US10233173, Example 559	Retinoic acid receptor RXR-alpha	Homo sapiens		 812					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276619&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309829	378158285							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524927	Cc1ccc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1C	InChI=1S/C18H17F3N4O/c1-11-4-7-17(22-12(11)2)26-10-13-9-25(24-23-13)14-5-6-16(19)15(8-14)18(3,20)21/h4-9H,10H2,1-3H3	PKXTZVWHAUOXPT-UHFFFAOYSA-N	276620	6-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-2,3-::US10071988, Example 560::US10233173, Example 560	Retinoic acid receptor RXR-alpha	Homo sapiens		 52.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276620&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309830	378158286							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524928	COc1ncccc1OCc1cn(nn1)-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C17H15F3N4O2/c1-17(19,20)13-8-12(5-6-14(13)18)24-9-11(22-23-24)10-26-15-4-3-7-21-16(15)25-2/h3-9H,10H2,1-2H3	GZJYBVRYMVLQSP-UHFFFAOYSA-N	276621	3-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-2-::US10071988, Example 561::US10233173, Example 561	Retinoic acid receptor RXR-alpha	Homo sapiens		 476					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276621&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309831	378158287							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524929	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C(F)F)nn1	InChI=1S/C16H12F5N5O/c1-16(20,21)12-4-11(2-3-13(12)17)26-7-10(24-25-26)8-27-15-22-5-9(6-23-15)14(18)19/h2-7,14H,8H2,1H3	JMIBTAQRPASKGS-UHFFFAOYSA-N	276622	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 562::US10233173, Example 562	Retinoic acid receptor RXR-alpha	Homo sapiens		 14.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276622&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309832	378158288							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524930	CC(F)(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)C(F)F)nn1	InChI=1S/C16H12F5N5O/c1-16(20,21)11-6-10(2-3-12(11)17)26-7-9(24-25-26)8-27-15-22-5-4-13(23-15)14(18)19/h2-7,14H,8H2,1H3	NYNUSIMBJRRLEK-UHFFFAOYSA-N	276623	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 563::US10233173, Example 563	Retinoic acid receptor RXR-alpha	Homo sapiens		 48.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276623&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309833	378158289							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524931	CC(F)(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)C(F)(F)F)nn1	InChI=1S/C16H11F6N5O/c1-15(18,19)11-6-10(2-3-12(11)17)27-7-9(25-26-27)8-28-14-23-5-4-13(24-14)16(20,21)22/h2-7H,8H2,1H3	FXYRDNGDEASMTM-UHFFFAOYSA-N	276624	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 564::US10233173, Example 564	Retinoic acid receptor RXR-alpha	Homo sapiens		 272					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276624&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309834	378158290							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524932	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C(C)(O)C(F)(F)F)nn1	InChI=1S/C18H15F6N5O2/c1-16(30,18(22,23)24)10-6-25-15(26-7-10)31-9-11-8-29(28-27-11)12-3-4-14(19)13(5-12)17(2,20)21/h3-8,30H,9H2,1-2H3	OLJVXJBLUJZOQD-UHFFFAOYSA-N	276625	(R/S)-2-[2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 565::US10233173, Example 565	Retinoic acid receptor RXR-alpha	Homo sapiens		 308					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276625&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309835	378158291							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524933	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C18H18F3N5O2/c1-17(2,27)11-7-22-16(23-8-11)28-10-12-9-26(25-24-12)13-4-5-15(19)14(6-13)18(3,20)21/h4-9,27H,10H2,1-3H3	GDYHYNDSXDZKOC-UHFFFAOYSA-N	276626	2-[2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 566::US10233173, Example 566	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276626&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302301	378158292							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524934	COC(C)(C)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C19H20F3N5O2/c1-18(2,28-4)12-8-23-17(24-9-12)29-11-13-10-27(26-25-13)14-5-6-16(20)15(7-14)19(3,21)22/h5-10H,11H2,1-4H3	LQPHLJRCTYMAOI-UHFFFAOYSA-N	276627	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-(1-::US10071988, Example 567::US10233173, Example 567	Retinoic acid receptor RXR-alpha	Homo sapiens		 4630					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276627&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309836	378158293							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524935	CC(F)(F)c1cc(ccc1F)-n1cc(COc2nccc(CO)n2)nn1	InChI=1S/C16H14F3N5O2/c1-16(18,19)13-6-12(2-3-14(13)17)24-7-11(22-23-24)9-26-15-20-5-4-10(8-25)21-15/h2-7,25H,8-9H2,1H3	YYRFWICHTUNFOK-UHFFFAOYSA-N	276628	US10071988, Example 568::US10233173, Example 568::[2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 25.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276628&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309837	378158294							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524936	COCc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C17H16F3N5O2/c1-17(19,20)14-5-13(3-4-15(14)18)25-8-12(23-24-25)10-27-16-21-6-11(7-22-16)9-26-2/h3-8H,9-10H2,1-2H3	ZUOKFMXOKGUICW-UHFFFAOYSA-N	276629	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 569::US10233173, Example 569	Retinoic acid receptor RXR-alpha	Homo sapiens		 89.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276629&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309840	378158295							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524937	COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)n1	InChI=1S/C17H16F3N5O2/c1-17(19,20)14-7-13(3-4-15(14)18)25-8-12(23-24-25)10-27-16-21-6-5-11(22-16)9-26-2/h3-8H,9-10H2,1-2H3	KJFLIQAORANJFE-UHFFFAOYSA-N	276630	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 570::US10233173, Example 570	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276630&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309838	378158296							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524938	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(CO)cn2)nn1	InChI=1S/C16H14F3N5O2/c1-16(18,19)13-4-12(2-3-14(13)17)24-7-11(22-23-24)9-26-15-20-5-10(8-25)6-21-15/h2-7,25H,8-9H2,1H3	GXWUNZYRWMEXFQ-UHFFFAOYSA-N	276631	US10071988, Example 571::US10233173, Example 571::[2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 21.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276631&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309839	378158297							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524939	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(OC(F)F)cn2)nn1	InChI=1S/C16H12F5N5O2/c1-16(20,21)12-4-10(2-3-13(12)17)26-7-9(24-25-26)8-27-15-22-5-11(6-23-15)28-14(18)19/h2-7,14H,8H2,1H3	WFBWOHGLKPPKMS-UHFFFAOYSA-N	276632	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 572::US10233173, Example 572	Retinoic acid receptor RXR-alpha	Homo sapiens		 25.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276632&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309841	378158298							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524940	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1C	InChI=1S/C17H16F3N5O/c1-10-7-21-16(22-11(10)2)26-9-12-8-25(24-23-12)13-4-5-15(18)14(6-13)17(3,19)20/h4-8H,9H2,1-3H3	HDQVIMHMXKCLPZ-UHFFFAOYSA-N	276633	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4,5-::US10071988, Example 573::US10233173, Example 573	Retinoic acid receptor RXR-alpha	Homo sapiens		 19.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276633&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309842	378158299							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524941	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)ncc1Cl	InChI=1S/C16H13ClF3N5O/c1-9-13(17)6-21-15(22-9)26-8-10-7-25(24-23-10)11-3-4-14(18)12(5-11)16(2,19)20/h3-7H,8H2,1-2H3	RIZKEXVVIREAHZ-UHFFFAOYSA-N	276634	5-Chloro-2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 574::US10233173, Example 574	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276634&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309845	378158300							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524942	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)ncc1F	InChI=1S/C16H13F4N5O/c1-9-14(18)6-21-15(22-9)26-8-10-7-25(24-23-10)11-3-4-13(17)12(5-11)16(2,19)20/h3-7H,8H2,1-2H3	MNUDHSVJARDHQP-UHFFFAOYSA-N	276635	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 575::US10233173, Example 575	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276635&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309843	378158301							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524943	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1N	InChI=1S/C16H15F3N6O/c1-9-6-21-15(22-14(9)20)26-8-10-7-25(24-23-10)11-3-4-13(17)12(5-11)16(2,18)19/h3-7H,8H2,1-2H3,(H2,20,21,22)	VKHWOFAGNRCYGU-UHFFFAOYSA-N	276636	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 576::US10233173, Example 576	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276636&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309846	378158302							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524944	CNc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)ncc1C	InChI=1S/C17H17F3N6O/c1-10-7-22-16(23-15(10)21-3)27-9-11-8-26(25-24-11)12-4-5-14(18)13(6-12)17(2,19)20/h4-8H,9H2,1-3H3,(H,21,22,23)	VUOWLVQOWAMXQW-UHFFFAOYSA-N	276637	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N,5-::US10071988, Example 577::US10233173, Example 577	Retinoic acid receptor RXR-alpha	Homo sapiens		 128					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276637&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309844	378158303							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524945	CNc1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)ncc1F	InChI=1S/C16H14F4N6O/c1-16(19,20)11-5-10(3-4-12(11)17)26-7-9(24-25-26)8-27-15-22-6-13(18)14(21-2)23-15/h3-7H,8H2,1-2H3,(H,21,22,23)	OPNOBXQLMZGSEV-UHFFFAOYSA-N	276638	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 578::US10233173, Example 578	Retinoic acid receptor RXR-alpha	Homo sapiens		 140					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276638&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309847	378158304							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524946	CN(C)c1nc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)ncc1C	InChI=1S/C18H19F3N6O/c1-11-8-22-17(23-16(11)26(3)4)28-10-12-9-27(25-24-12)13-5-6-15(19)14(7-13)18(2,20)21/h5-9H,10H2,1-4H3	QFCUTHKKKDIBFO-UHFFFAOYSA-N	276639	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-::US10071988, Example 579::US10233173, Example 579	Retinoic acid receptor RXR-alpha	Homo sapiens		 87.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276639&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309848	378158305							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524947	CC(F)(F)c1cc(ccc1F)-n1cc(COc2nccc(N)n2)nn1	InChI=1S/C15H13F3N6O/c1-15(17,18)11-6-10(2-3-12(11)16)24-7-9(22-23-24)8-25-14-20-5-4-13(19)21-14/h2-7H,8H2,1H3,(H2,19,20,21)	YXINWRMOIRXMJP-UHFFFAOYSA-N	276640	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 580::US10233173, Example 580	Retinoic acid receptor RXR-alpha	Homo sapiens		 88.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276640&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309850	378158306							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524948	CNc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)n1	InChI=1S/C16H15F3N6O/c1-16(18,19)12-7-11(3-4-13(12)17)25-8-10(23-24-25)9-26-15-21-6-5-14(20-2)22-15/h3-8H,9H2,1-2H3,(H,20,21,22)	MHGBPCHKZVKWKS-UHFFFAOYSA-N	276641	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 581::US10233173, Example 581	Retinoic acid receptor RXR-alpha	Homo sapiens		 33.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276641&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309849	378158307							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524949	CN(C)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)n1	InChI=1S/C17H17F3N6O/c1-17(19,20)13-8-12(4-5-14(13)18)26-9-11(23-24-26)10-27-16-21-7-6-15(22-16)25(2)3/h4-9H,10H2,1-3H3	DBXAGWCDLLONPH-UHFFFAOYSA-N	276642	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N,N-::US10071988, Example 582::US10233173, Example 582	Retinoic acid receptor RXR-alpha	Homo sapiens		 28.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276642&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309851	378158308							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524950	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C#N)nn1	InChI=1S/C16H11F3N6O/c1-16(18,19)13-4-12(2-3-14(13)17)25-8-11(23-24-25)9-26-15-21-6-10(5-20)7-22-15/h2-4,6-8H,9H2,1H3	MUVBNZVUMQVZHR-UHFFFAOYSA-N	276643	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 583::US10233173, Example 583	Retinoic acid receptor RXR-alpha	Homo sapiens		 67.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276643&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309852	378158309							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524951	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)S(C)(=O)=O)nn1	InChI=1S/C16H14F3N5O3S/c1-16(18,19)13-5-11(3-4-14(13)17)24-8-10(22-23-24)9-27-15-20-6-12(7-21-15)28(2,25)26/h3-8H,9H2,1-2H3	SGWPDDLRSIMATJ-UHFFFAOYSA-N	276644	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 584::US10233173, Example 584	Retinoic acid receptor RXR-alpha	Homo sapiens		 199					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276644&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309853	378158310							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524952	CC(=O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C17H14F3N5O2/c1-10(26)11-6-21-16(22-7-11)27-9-12-8-25(24-23-12)13-3-4-15(18)14(5-13)17(2,19)20/h3-8H,9H2,1-2H3	FHTLCZYTLPYTMO-UHFFFAOYSA-N	276645	1-[2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 585::US10233173, Example 585	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276645&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302364	378158311							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524953	CC(O)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C17H16F3N5O2/c1-10(26)11-6-21-16(22-7-11)27-9-12-8-25(24-23-12)13-3-4-15(18)14(5-13)17(2,19)20/h3-8,10,26H,9H2,1-2H3	IBSHDUNQNHANES-UHFFFAOYSA-N	276646	(R/S)-1-[2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 586::US10233173, Example 586	Retinoic acid receptor RXR-alpha	Homo sapiens		 14.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276646&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309854	378158312							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524954	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C18H16F3N5O/c1-18(20,21)15-6-14(4-5-16(15)19)26-9-13(24-25-26)10-27-17-22-7-12(8-23-17)11-2-3-11/h4-9,11H,2-3,10H2,1H3	UNWVKNIGRUANAZ-UHFFFAOYSA-N	276647	5-Cyclopropyl-2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 587::US10233173, Example 587	Retinoic acid receptor RXR-alpha	Homo sapiens		 41.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276647&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309855	378158313							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524955	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CCC2)nn1	InChI=1S/C18H17F3N6O/c1-18(20,21)15-7-13(3-4-16(15)19)27-10-12(24-25-27)11-28-17-22-8-14(9-23-17)26-5-2-6-26/h3-4,7-10H,2,5-6,11H2,1H3	ZHPFOPTYQMCQCZ-UHFFFAOYSA-N	276648	5-(Azetidin-1-yl)-2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]triazol-4-::US10071988, Example 588::US10233173, Example 588	Retinoic acid receptor RXR-alpha	Homo sapiens		 34.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276648&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302190	378158314							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524956	CC(F)(F)c1cc(ccc1F)-n1cc(COc2ncc(cn2)N2CC(F)C2)nn1	InChI=1S/C18H16F4N6O/c1-18(21,22)15-4-13(2-3-16(15)20)28-9-12(25-26-28)10-29-17-23-5-14(6-24-17)27-7-11(19)8-27/h2-6,9,11H,7-8,10H2,1H3	UZLQVSWICMHFOQ-UHFFFAOYSA-N	276649	2-((1-(3-(1,1-Difluoroethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 589::US10233173, Example 589	Retinoic acid receptor RXR-alpha	Homo sapiens		 13.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276649&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302470	378158315							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524957	CN(C)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C17H17F3N6O/c1-17(19,20)14-6-12(4-5-15(14)18)26-9-11(23-24-26)10-27-16-21-7-13(8-22-16)25(2)3/h4-9H,10H2,1-3H3	WKJNJMVKIZPRSV-UHFFFAOYSA-N	276650	2-((1-(3-(1,1-Difluoroethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 590::US10233173, Example 590	Retinoic acid receptor RXR-alpha	Homo sapiens		 39.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276650&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309856	378158316							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524958	CC(F)(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)N2CCCC2)nn1	InChI=1S/C19H19F3N6O/c1-19(21,22)15-10-14(4-5-16(15)20)28-11-13(25-26-28)12-29-18-23-7-6-17(24-18)27-8-2-3-9-27/h4-7,10-11H,2-3,8-9,12H2,1H3	CWZJNVCLWRLJKV-UHFFFAOYSA-N	276651	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 591::US10233173, Example 591	Retinoic acid receptor RXR-alpha	Homo sapiens		 16.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276651&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309857	378158317							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524959	CC(F)(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)N2CCCCC2)nn1	InChI=1S/C20H21F3N6O/c1-20(22,23)16-11-15(5-6-17(16)21)29-12-14(26-27-29)13-30-19-24-8-7-18(25-19)28-9-3-2-4-10-28/h5-8,11-12H,2-4,9-10,13H2,1H3	JZWDJAUGTODXDU-UHFFFAOYSA-N	276652	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-4-(1-::US10071988, Example 592::US10233173, Example 592	Retinoic acid receptor RXR-alpha	Homo sapiens		 271					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276652&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309858	378158318							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524960	CCc1cnc(OCc2nnn(c2C)-c2ccc(F)c(c2)C(C)(F)F)nc1	InChI=1S/C18H18F3N5O/c1-4-12-8-22-17(23-9-12)27-10-16-11(2)26(25-24-16)13-5-6-15(19)14(7-13)18(3,20)21/h5-9H,4,10H2,1-3H3	UOYXAELJTNYLFT-UHFFFAOYSA-N	276653	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]-5-methyl-triazol-4-::US10071988, Example 593::US10233173, Example 593	Retinoic acid receptor RXR-alpha	Homo sapiens		 486					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276653&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309860	378158319							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524961	Cc1c(COc2ncc(cn2)C2CC2)nnn1-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C19H18F3N5O/c1-11-17(10-28-18-23-8-13(9-24-18)12-3-4-12)25-26-27(11)14-5-6-16(20)15(7-14)19(2,21)22/h5-9,12H,3-4,10H2,1-2H3	VJRJHCRZWAUSIS-UHFFFAOYSA-N	276654	5-Cyclopropyl-2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]-5-methyl-::US10071988, Example 594::US10233173, Example 594	Retinoic acid receptor RXR-alpha	Homo sapiens		 171					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276654&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309859	378158320							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524962	Cc1c(COc2ncc(C)c(C)n2)nnn1-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C18H18F3N5O/c1-10-8-22-17(23-11(10)2)27-9-16-12(3)26(25-24-16)13-5-6-15(19)14(7-13)18(4,20)21/h5-8H,9H2,1-4H3	ZFMRRIOPPCYIIG-UHFFFAOYSA-N	276655	2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]-5-methyl-triazol-4-::US10071988, Example 595::US10233173, Example 595	Retinoic acid receptor RXR-alpha	Homo sapiens		 706					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276655&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309862	378158321							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524963	Cc1c(COc2ncc(Cl)c(C)n2)nnn1-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C17H15ClF3N5O/c1-9-13(18)7-22-16(23-9)27-8-15-10(2)26(25-24-15)11-4-5-14(19)12(6-11)17(3,20)21/h4-7H,8H2,1-3H3	IJXSQBLKEBMRLI-UHFFFAOYSA-N	276656	5-Chloro-2-[[1-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]-5-methyl-triazol-::US10071988, Example 596::US10233173, Example 596	Retinoic acid receptor RXR-alpha	Homo sapiens		 601					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276656&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309865	378158322							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524964	Fc1ccc(cc1F)-n1cc(COc2ncccn2)nn1	InChI=1S/C13H9F2N5O/c14-11-3-2-10(6-12(11)15)20-7-9(18-19-20)8-21-13-16-4-1-5-17-13/h1-7H,8H2	XSHLRZCSETXEPD-UHFFFAOYSA-N	276657	2-[[1-(3,4-Difluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 597::US10233173, Example 597	Retinoic acid receptor RXR-alpha	Homo sapiens		 2100					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276657&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309863	378158323							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524965	Fc1cnc(OCc2cn(nn2)-c2ccc(F)c(F)c2)nc1	InChI=1S/C13H8F3N5O/c14-8-4-17-13(18-5-8)22-7-9-6-21(20-19-9)10-1-2-11(15)12(16)3-10/h1-6H,7H2	NQMYZOXRPLSQIH-UHFFFAOYSA-N	276658	2-[[1-(3,4-Difluorophenyl)triazol-4-yl]methoxy]-5-fluoro-pyrimidine;::US10071988, Example 598::US10071988, Example 600::US10233173, Example 600	Retinoic acid receptor RXR-alpha	Homo sapiens		 1450					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276658&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309864	378158324							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524966	COc1cnc(OCc2cn(nn2)-c2ccc(F)c(F)c2)nc1	InChI=1S/C14H11F2N5O2/c1-22-11-5-17-14(18-6-11)23-8-9-7-21(20-19-9)10-2-3-12(15)13(16)4-10/h2-7H,8H2,1H3	YRCHIHCHYHEHSX-UHFFFAOYSA-N	276659	2-[[1-(3,4-Difluorophenyl)triazol-4-yl]methoxy]-5-methoxy-pyrimidine;::US10071988, Example 599::US10233173, Example 599	Retinoic acid receptor RXR-alpha	Homo sapiens		 34.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276659&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309866	378158325							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524967	Fc1cnc(OCc2cn(nn2)-c2ccc(F)c(F)c2)nc1	InChI=1S/C13H8F3N5O/c14-8-4-17-13(18-5-8)22-7-9-6-21(20-19-9)10-1-2-11(15)12(16)3-10/h1-6H,7H2	NQMYZOXRPLSQIH-UHFFFAOYSA-N	276658	2-[[1-(3,4-Difluorophenyl)triazol-4-yl]methoxy]-5-fluoro-pyrimidine;::US10071988, Example 598::US10071988, Example 600::US10233173, Example 600	Retinoic acid receptor RXR-alpha	Homo sapiens		 238					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276658&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309864	378158324							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524968	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(F)c2)nc1	InChI=1S/C14H11F2N5O/c1-9-5-17-14(18-6-9)22-8-10-7-21(20-19-10)11-2-3-12(15)13(16)4-11/h2-7H,8H2,1H3	QBIATVXHIIPAMI-UHFFFAOYSA-N	276661	2-[[1-(3,4-Difluorophenyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 601::US10233173, Example 601	Retinoic acid receptor RXR-alpha	Homo sapiens		 48.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276661&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309867	378158326							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524969	CCc1cnc(OCc2cn(nn2)-c2ccc(F)c(F)c2)nc1	InChI=1S/C15H13F2N5O/c1-2-10-6-18-15(19-7-10)23-9-11-8-22(21-20-11)12-3-4-13(16)14(17)5-12/h3-8H,2,9H2,1H3	DVEIBKQAXUNVHU-UHFFFAOYSA-N	276662	2-[[1-(3,4-Difluorophenyl)triazol-4-yl]methoxy]-5-ethyl-pyrimidine;::US10071988, Example 602::US10233173, Example 602	Retinoic acid receptor RXR-alpha	Homo sapiens		 23.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276662&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309868	378158327							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524970	Cc1cnc(OCc2cn(nn2)-c2cc(F)ccc2F)nc1	InChI=1S/C14H11F2N5O/c1-9-5-17-14(18-6-9)22-8-11-7-21(20-19-11)13-4-10(15)2-3-12(13)16/h2-7H,8H2,1H3	GBHNIHCIAKIREI-UHFFFAOYSA-N	276663	2-[[1-(2,5-Difluorophenyl)triazol-4-yl]methoxy]-5-methyl-pyrimidine;::US10071988, Example 603::US10233173, Example 603	Retinoic acid receptor RXR-alpha	Homo sapiens		 10430					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276663&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309869	378158328							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524971	CC(C)(O)c1cnc(OCc2cn(nn2)-c2cc(F)ccc2F)nc1	InChI=1S/C16H15F2N5O2/c1-16(2,24)10-6-19-15(20-7-10)25-9-12-8-23(22-21-12)14-5-11(17)3-4-13(14)18/h3-8,24H,9H2,1-2H3	XFSIGTROBGQHGD-UHFFFAOYSA-N	276664	2-[2-[[1-(2,5-Difluorophenyl)triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 604::US10233173, Example 604	Retinoic acid receptor RXR-alpha	Homo sapiens		 79708					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276664&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309870	378158329							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524972	Fc1cccc(c1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C13H8ClF2N5O/c14-8-4-17-13(18-5-8)22-7-9-6-21(20-19-9)11-3-1-2-10(15)12(11)16/h1-6H,7H2	HKMBNBINDGSSCH-UHFFFAOYSA-N	276665	5-Chloro-2-[[1-(2,3-difluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 605::US10233173, Example 605	Retinoic acid receptor RXR-alpha	Homo sapiens		 4360					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276665&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309871	378158330							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524973	Fc1cnc(OCc2cn(nn2)-c2cccc(F)c2F)nc1	InChI=1S/C13H8F3N5O/c14-8-4-17-13(18-5-8)22-7-9-6-21(20-19-9)11-3-1-2-10(15)12(11)16/h1-6H,7H2	QHNXVHCPNMIAJV-UHFFFAOYSA-N	276666	2-[[1-(2,3-Difluorophenyl)triazol-4-yl]methoxy]-5-fluoro-pyrimidine;::US10071988, Example 606::US10233173, Example 606	Retinoic acid receptor RXR-alpha	Homo sapiens		 17499					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276666&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309872	378158331							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524974	Fc1cccc(c1F)-n1cc(COc2ncccn2)nn1	InChI=1S/C13H9F2N5O/c14-10-3-1-4-11(12(10)15)20-7-9(18-19-20)8-21-13-16-5-2-6-17-13/h1-7H,8H2	MWMFDQPXYFRZFX-UHFFFAOYSA-N	276667	2-[[1-(2,3-Difluorophenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 607::US10233173, Example 607	Retinoic acid receptor RXR-alpha	Homo sapiens		 3425					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276667&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309873	378158332							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524975	CC(C)(O)c1cnc(OCc2cn(nn2)-c2cccc(F)c2F)nc1	InChI=1S/C16H15F2N5O2/c1-16(2,24)10-6-19-15(20-7-10)25-9-11-8-23(22-21-11)13-5-3-4-12(17)14(13)18/h3-8,24H,9H2,1-2H3	RPWWBYFCWBCVHT-UHFFFAOYSA-N	276668	2-[2-[[1-(2,3-Difluorophenyl)triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 608::US10233173, Example 608	Retinoic acid receptor RXR-alpha	Homo sapiens		>10000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276668&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309874	378158333							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524976	Cc1nc(OCc2cn(nn2)-c2cccc(F)c2F)ncc1F	InChI=1S/C14H10F3N5O/c1-8-11(16)5-18-14(19-8)23-7-9-6-22(21-20-9)12-4-2-3-10(15)13(12)17/h2-6H,7H2,1H3	JWBKTOPCJJMRNG-UHFFFAOYSA-N	276669	2-[[1-(2,3-Difluorophenyl)triazol-4-yl]methoxy]-5-fluoro-4-methyl-::US10071988, Example 609::US10233173, Example 609	Retinoic acid receptor RXR-alpha	Homo sapiens		 15900					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276669&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309875	378158334							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524977	Cc1cnc(OCc2cn(nn2)-c2cccc(Cl)c2F)nc1	InChI=1S/C14H11ClFN5O/c1-9-5-17-14(18-6-9)22-8-10-7-21(20-19-10)12-4-2-3-11(15)13(12)16/h2-7H,8H2,1H3	VALYJQJWXARFKM-UHFFFAOYSA-N	276670	2-[[1-(3-Chloro-2-fluoro-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 610::US10233173, Example 610	Retinoic acid receptor RXR-alpha	Homo sapiens		 1034					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276670&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309876	378158335							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524978	Fc1c(Cl)cccc1-n1cc(COc2ncccn2)nn1	InChI=1S/C13H9ClFN5O/c14-10-3-1-4-11(12(10)15)20-7-9(18-19-20)8-21-13-16-5-2-6-17-13/h1-7H,8H2	BCGUPHXAJRGPCE-UHFFFAOYSA-N	276671	2-[[1-(3-Chloro-2-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 611::US10233173, Example 611	Retinoic acid receptor RXR-alpha	Homo sapiens		>10000					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276671&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309877	378158336							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524979	Fc1c(Cl)cccc1-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C13H8Cl2FN5O/c14-8-4-17-13(18-5-8)22-7-9-6-21(20-19-9)11-3-1-2-10(15)12(11)16/h1-6H,7H2	FLEJSAQUPPZXGG-UHFFFAOYSA-N	276672	5-Chloro-2-[[1-(3-chloro-2-fluoro-phenyl)triazol-4-::US10071988, Example 612::US10233173, Example 612	Retinoic acid receptor RXR-alpha	Homo sapiens		 1737					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276672&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309879	378158337							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524980	Cc1nc(OCc2cn(nn2)-c2cccc(Cl)c2F)ncc1F	InChI=1S/C14H10ClF2N5O/c1-8-11(16)5-18-14(19-8)23-7-9-6-22(21-20-9)12-4-2-3-10(15)13(12)17/h2-6H,7H2,1H3	SJLPOYCNAZIVMV-UHFFFAOYSA-N	276673	2-[[1-(3-Chloro-2-fluoro-phenyl)triazol-4-yl]methoxy]-5-fluoro-4-::US10071988, Example 613::US10233173, Example 613	Retinoic acid receptor RXR-alpha	Homo sapiens		 1441					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276673&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309878	378158338							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524981	Fc1cnc(OCc2cn(nn2)-c2cccc(Cl)c2F)nc1	InChI=1S/C13H8ClF2N5O/c14-10-2-1-3-11(12(10)16)21-6-9(19-20-21)7-22-13-17-4-8(15)5-18-13/h1-6H,7H2	WPEIHKURSWVFPX-UHFFFAOYSA-N	276674	2-[[1-(3-Chloro-2-fluoro-phenyl)triazol-4-yl]methoxy]-5-fluoro-::US10071988, Example 614::US10233173, Example 614	Retinoic acid receptor RXR-alpha	Homo sapiens		 4032					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276674&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309880	378158339							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524982	CC(C)(O)c1cnc(OCc2cn(nn2)-c2cccc(Cl)c2F)nc1	InChI=1S/C16H15ClFN5O2/c1-16(2,24)10-6-19-15(20-7-10)25-9-11-8-23(22-21-11)13-5-3-4-12(17)14(13)18/h3-8,24H,9H2,1-2H3	QEURAYQJZGAICJ-UHFFFAOYSA-N	276675	2-[2-[[1-(3-Chloro-2-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidin-5-::US10071988, Example 615::US10233173, Example 615	Retinoic acid receptor RXR-alpha	Homo sapiens		 4658					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276675&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309881	378158340							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524983	OCc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1	InChI=1S/C14H11BrFN5O2/c15-12-3-11(1-2-13(12)16)21-6-10(19-20-21)8-23-14-17-4-9(7-22)5-18-14/h1-6,22H,7-8H2	HIOJOKNCHBKSBH-UHFFFAOYSA-N	276676	US10071988, Example 616::US10233173, Example 616::[2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidin-5-	Retinoic acid receptor RXR-alpha	Homo sapiens		 30.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276676&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309882	378158341							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524984	OCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)n1	InChI=1S/C14H11BrFN5O2/c15-12-5-11(1-2-13(12)16)21-6-10(19-20-21)8-23-14-17-4-3-9(7-22)18-14/h1-6,22H,7-8H2	XASAWCRQWYULED-UHFFFAOYSA-N	276677	US10071988, Example 617::US10233173, Example 617::[2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidin-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 41.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276677&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309883	378158342							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524985	FCCOc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1	InChI=1S/C15H12BrF2N5O2/c16-13-5-11(1-2-14(13)18)23-8-10(21-22-23)9-25-15-19-6-12(7-20-15)24-4-3-17/h1-2,5-8H,3-4,9H2	CPHUVJUYKFJFQT-UHFFFAOYSA-N	276678	2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-(2-::US10071988, Example 618::US10233173, Example 618	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276678&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309884	378158343							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524986	Fc1ccc(cc1Cl)-n1cc(COc2ncccn2)nn1	InChI=1S/C13H9ClFN5O/c14-11-6-10(2-3-12(11)15)20-7-9(18-19-20)8-21-13-16-4-1-5-17-13/h1-7H,8H2	YHFXCJPUHUQJSY-UHFFFAOYSA-N	276679	2-[[1-(3-Chloro-4-fluoro-phenyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 619::US10233173, Example 619	Retinoic acid receptor RXR-alpha	Homo sapiens		 217					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276679&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309885	378158344							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524987	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(Cl)c2)nc1	InChI=1S/C14H11ClFN5O/c1-9-5-17-14(18-6-9)22-8-10-7-21(20-19-10)11-2-3-13(16)12(15)4-11/h2-7H,8H2,1H3	ZVBYAYLUIRDWCH-UHFFFAOYSA-N	276680	2-[[1-(3-Chloro-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 620::US10233173, Example 620	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276680&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309886	378158345							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524988	CCc1cnc(OCc2cn(nn2)-c2ccc(F)c(Cl)c2)nc1	InChI=1S/C15H13ClFN5O/c1-2-10-6-18-15(19-7-10)23-9-11-8-22(21-20-11)12-3-4-14(17)13(16)5-12/h3-8H,2,9H2,1H3	HULXCRLXLOALTM-UHFFFAOYSA-N	276681	2-[[1-(3-Chloro-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-ethyl-::US10071988, Example 621::US10233173, Example 621	Retinoic acid receptor RXR-alpha	Homo sapiens		 3.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276681&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309889	378158346							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524989	COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(Cl)c2)n1	InChI=1S/C15H13ClFN5O2/c1-23-8-10-4-5-18-15(19-10)24-9-11-7-22(21-20-11)12-2-3-14(17)13(16)6-12/h2-7H,8-9H2,1H3	VOLGXNUYEULAFC-UHFFFAOYSA-N	276682	2-[[1-(3-Chloro-4-fluoro-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 622::US10233173, Example 622	Retinoic acid receptor RXR-alpha	Homo sapiens		 66.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276682&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309887	378158347							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524990	CC(C)c1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C17H16ClF2N5O/c1-10(2)15-5-6-21-17(22-15)26-9-11-8-25(24-23-11)12-3-4-14(18)13(7-12)16(19)20/h3-8,10,16H,9H2,1-2H3	DFALROLCFWWLDX-UHFFFAOYSA-N	276683	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 623::US10233173, Example 623	Retinoic acid receptor RXR-alpha	Homo sapiens		 129					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276683&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309888	378158348							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524991	OCc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C15H12ClF2N5O2/c16-13-2-1-11(3-12(13)14(17)18)23-6-10(21-22-23)8-25-15-19-4-9(7-24)5-20-15/h1-6,14,24H,7-8H2	XPKMABARXLUKOM-UHFFFAOYSA-N	276684	US10071988, Example 624::US10233173, Example 624::[2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 20.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276684&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309890	378158349							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524992	OCc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C15H12ClF2N5O2/c16-13-2-1-11(5-12(13)14(17)18)23-6-10(21-22-23)8-25-15-19-4-3-9(7-24)20-15/h1-6,14,24H,7-8H2	QGXKECXEFKDWGY-UHFFFAOYSA-N	276685	US10071988, Example 625::US10233173, Example 625::[2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-	Retinoic acid receptor RXR-alpha	Homo sapiens		 17.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276685&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309891	378158350							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524993	CC(C)(O)c1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C17H16ClF2N5O2/c1-17(2,26)10-6-21-16(22-7-10)27-9-11-8-25(24-23-11)12-3-4-14(18)13(5-12)15(19)20/h3-8,15,26H,9H2,1-2H3	MESRDXBHSIOUFS-UHFFFAOYSA-N	276686	2-[2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-::US10071988, Example 626	Retinoic acid receptor RXR-alpha	Homo sapiens		 67.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276686&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309893	378158351							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524994	COCc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C16H14ClF2N5O2/c1-25-8-10-4-5-20-16(21-10)26-9-11-7-24(23-22-11)12-2-3-14(17)13(6-12)15(18)19/h2-7,15H,8-9H2,1H3	KQOXIJOKIBPFHT-UHFFFAOYSA-N	276687	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 627::US10233173, Example 627	Retinoic acid receptor RXR-alpha	Homo sapiens		 38.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276687&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309892	378158352							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524995	FC(F)c1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C15H10ClF4N5O/c16-11-2-1-9(5-10(11)13(17)18)25-6-8(23-24-25)7-26-15-21-4-3-12(22-15)14(19)20/h1-6,13-14H,7H2	CAGIHHHPMFGUSU-UHFFFAOYSA-N	276688	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 628::US10233173, Example 628	Retinoic acid receptor RXR-alpha	Homo sapiens		 42.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276688&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309894	378158353							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524996	CN(C)c1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C16H15ClF2N6O/c1-24(2)14-5-6-20-16(21-14)26-9-10-8-25(23-22-10)11-3-4-13(17)12(7-11)15(18)19/h3-8,15H,9H2,1-2H3	LHVZUOMTHMLBFU-UHFFFAOYSA-N	276689	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-N,N-::US10071988, Example 629::US10233173, Example 629	Retinoic acid receptor RXR-alpha	Homo sapiens		 7.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276689&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309895	378158354							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524997	FC(F)c1cc(ccc1Cl)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C17H14ClF2N5O/c18-15-4-3-13(5-14(15)16(19)20)25-8-12(23-24-25)9-26-17-21-6-11(7-22-17)10-1-2-10/h3-8,10,16H,1-2,9H2	XEZVPMCTUXYBQL-UHFFFAOYSA-N	276690	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 630::US10233173, Example 630	Retinoic acid receptor RXR-alpha	Homo sapiens		 13.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276690&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309896	378158355							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524998	FC(F)c1cc(ccc1Cl)-n1cc(COc2nccc(n2)C2CC2)nn1	InChI=1S/C17H14ClF2N5O/c18-14-4-3-12(7-13(14)16(19)20)25-8-11(23-24-25)9-26-17-21-6-5-15(22-17)10-1-2-10/h3-8,10,16H,1-2,9H2	DBJDMGBZYSQFGL-UHFFFAOYSA-N	276691	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 631::US10233173, Example 631	Retinoic acid receptor RXR-alpha	Homo sapiens		 42.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276691&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309897	378158356							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
524999	Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1N	InChI=1S/C15H13ClF2N6O/c1-8-5-20-15(21-14(8)19)25-7-9-6-24(23-22-9)10-2-3-12(16)11(4-10)13(17)18/h2-6,13H,7H2,1H3,(H2,19,20,21)	RXZGQGQMBBZIRR-UHFFFAOYSA-N	276692	2-[[1-[4-chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 632::US10233173, Example 632	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276692&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309898	378158357							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525000	CN(C)c1nc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)ncc1C	InChI=1S/C17H17ClF2N6O/c1-10-7-21-17(22-16(10)25(2)3)27-9-11-8-26(24-23-11)12-4-5-14(18)13(6-12)15(19)20/h4-8,15H,9H2,1-3H3	LBXUADOVPYMHAT-UHFFFAOYSA-N	276693	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-N,N,5-::US10071988, Example 633::US10233173, Example 633	Retinoic acid receptor RXR-alpha	Homo sapiens		 57.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276693&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309899	378158358							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525001	FC(F)c1cc(ccc1Cl)-n1cc(COc2nccc(n2)N2CCCC2)nn1	InChI=1S/C18H17ClF2N6O/c19-15-4-3-13(9-14(15)17(20)21)27-10-12(24-25-27)11-28-18-22-6-5-16(23-18)26-7-1-2-8-26/h3-6,9-10,17H,1-2,7-8,11H2	PIOWRJHOKBGOGG-UHFFFAOYSA-N	276694	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-::US10071988, Example 634::US10233173, Example 634	Retinoic acid receptor RXR-alpha	Homo sapiens		 12.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276694&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309901	378158359							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525002	FC(F)c1cc(ccc1Cl)-n1cc(COc2nccc(n2)N2CCCCC2)nn1	InChI=1S/C19H19ClF2N6O/c20-16-5-4-14(10-15(16)18(21)22)28-11-13(25-26-28)12-29-19-23-7-6-17(24-19)27-8-2-1-3-9-27/h4-7,10-11,18H,1-3,8-9,12H2	WNWKKJPWPQBNPZ-UHFFFAOYSA-N	276695	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-4-(1-::US10071988, Example 635::US10233173, Example 635	Retinoic acid receptor RXR-alpha	Homo sapiens		 169					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276695&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302462	378158360							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525003	FCCOc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C16H13ClF3N5O2/c17-14-2-1-11(5-13(14)15(19)20)25-8-10(23-24-25)9-27-16-21-6-12(7-22-16)26-4-3-18/h1-2,5-8,15H,3-4,9H2	GGZGAPFHVRPYNU-UHFFFAOYSA-N	276696	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-(2-::US10071988, Example 636::US10233173, Example 636	Retinoic acid receptor RXR-alpha	Homo sapiens		 10.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276696&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309900	378158361							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525004	FCCCc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1	InChI=1S/C17H15ClF3N5O/c18-15-4-3-13(6-14(15)16(20)21)26-9-12(24-25-26)10-27-17-22-7-11(8-23-17)2-1-5-19/h3-4,6-9,16H,1-2,5,10H2	RSVHZTMSZJPPPX-UHFFFAOYSA-N	276697	2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-(3-::US10071988, Example 637::US10233173, Example 637	Retinoic acid receptor RXR-alpha	Homo sapiens		 11.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276697&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309914	378158362							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525005	Cc1cnc(OCc2cn(nn2)-c2ccc(N3CCC3)c(c2)C(F)F)nc1	InChI=1S/C18H18F2N6O/c1-12-8-21-18(22-9-12)27-11-13-10-26(24-23-13)14-3-4-16(25-5-2-6-25)15(7-14)17(19)20/h3-4,7-10,17H,2,5-6,11H2,1H3	SYEXGVYKRSIVLD-UHFFFAOYSA-N	276698	2-((1-(4-(Azetidin-1-yl)-3-(difluoromethyl)phenyl)-1H-1,2,3-triazol-4-::US10071988, Example 638::US10233173, Example 638	Retinoic acid receptor RXR-alpha	Homo sapiens		 511					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276698&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309907	378158363							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525006	CC(C)c1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)nc1	InChI=1S/C17H17F2N5O/c1-10(2)12-6-20-17(21-7-12)25-9-13-8-24(23-22-13)15-5-4-14(18)11(3)16(15)19/h4-8,10H,9H2,1-3H3	AURXIYAXLFSDDJ-UHFFFAOYSA-N	276699	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-isopropyl-::US10071988, Example 639::US10233173, Example 639	Retinoic acid receptor RXR-alpha	Homo sapiens		 52.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276699&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309902	378158364							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525007	CC(C)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)n1	InChI=1S/C17H17F2N5O/c1-10(2)14-6-7-20-17(21-14)25-9-12-8-24(23-22-12)15-5-4-13(18)11(3)16(15)19/h4-8,10H,9H2,1-3H3	BIDDYKAHINZFMW-UHFFFAOYSA-N	276700	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4-isopropyl-::US10071988, Example 640::US10233173, Example 640	Retinoic acid receptor RXR-alpha	Homo sapiens		 1980					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276700&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309903	378158365							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525008	Cc1c(F)ccc(c1F)-n1cc(COc2ncc(cn2)C(F)F)nn1	InChI=1S/C15H11F4N5O/c1-8-11(16)2-3-12(13(8)17)24-6-10(22-23-24)7-25-15-20-4-9(5-21-15)14(18)19/h2-6,14H,7H2,1H3	CBGIMBZDUZIEFC-UHFFFAOYSA-N	276701	5-(Difluoromethyl)-2-[[1-(2,4-difluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 641::US10233173, Example 641	Retinoic acid receptor RXR-alpha	Homo sapiens		 111					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276701&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309908	378158366							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525009	Cc1c(F)ccc(c1F)-n1cc(COc2nccc(n2)C(F)F)nn1	InChI=1S/C15H11F4N5O/c1-8-10(16)2-3-12(13(8)17)24-6-9(22-23-24)7-25-15-20-5-4-11(21-15)14(18)19/h2-6,14H,7H2,1H3	XPNLVJFSGTYIOT-UHFFFAOYSA-N	276702	4-(Difluoromethyl)-2-[[1-(2,4-difluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 642::US10233173, Example 642	Retinoic acid receptor RXR-alpha	Homo sapiens		 2210					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276702&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309915	378158367							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525010	Cc1c(F)ccc(c1F)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H10F5N5O/c1-8-11(16)2-3-12(13(8)17)25-6-10(23-24-25)7-26-14-21-4-9(5-22-14)15(18,19)20/h2-6H,7H2,1H3	LLURBDUOKQMCDJ-UHFFFAOYSA-N	276703	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-::US10071988, Example 643::US10233173, Example 643	Retinoic acid receptor RXR-alpha	Homo sapiens		 200					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276703&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309904	378158368							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525011	Cc1c(F)ccc(c1F)-n1cc(COc2ncc(cn2)C(C)(C)O)nn1	InChI=1S/C17H17F2N5O2/c1-10-13(18)4-5-14(15(10)19)24-8-12(22-23-24)9-26-16-20-6-11(7-21-16)17(2,3)25/h4-8,25H,9H2,1-3H3	FZLQEVUWSGPOFB-UHFFFAOYSA-N	276704	2-[2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]pyrimidin-::US10071988, Example 644::US10233173, Example 644	Retinoic acid receptor RXR-alpha	Homo sapiens		 967					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276704&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309909	378158369							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525012	COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)n1	InChI=1S/C16H15F2N5O2/c1-10-13(17)3-4-14(15(10)18)23-7-12(21-22-23)9-25-16-19-6-5-11(20-16)8-24-2/h3-7H,8-9H2,1-2H3	CTPORCSSYPKFMJ-UHFFFAOYSA-N	276705	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 645::US10233173, Example 645	Retinoic acid receptor RXR-alpha	Homo sapiens		 799					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276705&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309905	378158370							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525013	Cc1c(F)ccc(c1F)-n1cc(COc2ncc(OC(F)F)cn2)nn1	InChI=1S/C15H11F4N5O2/c1-8-11(16)2-3-12(13(8)17)24-6-9(22-23-24)7-25-15-20-4-10(5-21-15)26-14(18)19/h2-6,14H,7H2,1H3	JTWFIWSZKPSTJH-UHFFFAOYSA-N	276706	5-(Difluoromethoxy)-2-[[1-(2,4-difluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 646::US10233173, Example 646	Retinoic acid receptor RXR-alpha	Homo sapiens		 99.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276706&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309916	378158371							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525014	Cc1c(F)ccc(c1F)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C17H15F2N5O/c1-10-14(18)4-5-15(16(10)19)24-8-13(22-23-24)9-25-17-20-6-12(7-21-17)11-2-3-11/h4-8,11H,2-3,9H2,1H3	HFOGNCQXXZSGTN-UHFFFAOYSA-N	276707	5-Cyclopropyl-2-[[1-(2,4-difluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 647::US10233173, Example 647	Retinoic acid receptor RXR-alpha	Homo sapiens		 34.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276707&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309906	378158372							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525015	Cc1c(F)ccc(c1F)-n1cc(COc2nccc(n2)C2CC2)nn1	InChI=1S/C17H15F2N5O/c1-10-13(18)4-5-15(16(10)19)24-8-12(22-23-24)9-25-17-20-7-6-14(21-17)11-2-3-11/h4-8,11H,2-3,9H2,1H3	MDYRWATVEPKITO-UHFFFAOYSA-N	276708	4-Cyclopropyl-2-[[1-(2,4-difluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 648::US10233173, Example 648	Retinoic acid receptor RXR-alpha	Homo sapiens		 592					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276708&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309911	378158373							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525016	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)ncc1F	InChI=1S/C15H12F3N5O/c1-8-11(16)3-4-13(14(8)18)23-6-10(21-22-23)7-24-15-19-5-12(17)9(2)20-15/h3-6H,7H2,1-2H3	QXGOKMPAHSMLMY-UHFFFAOYSA-N	276709	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-fluoro-4-::US10071988, Example 649::US10233173, Example 649	Retinoic acid receptor RXR-alpha	Homo sapiens		 152					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276709&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309912	378158374							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525017	Cc1nc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)ncc1Cl	InChI=1S/C15H12ClF2N5O/c1-8-12(17)3-4-13(14(8)18)23-6-10(21-22-23)7-24-15-19-5-11(16)9(2)20-15/h3-6H,7H2,1-2H3	BDRYVOLIZIGDFG-UHFFFAOYSA-N	276710	5-Chloro-2-[[1-(2,4-difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 650::US10233173, Example 650	Retinoic acid receptor RXR-alpha	Homo sapiens		 5.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276710&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309927	378158375							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525018	Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2F)nc1N	InChI=1S/C15H14F2N6O/c1-8-5-19-15(20-14(8)18)24-7-10-6-23(22-21-10)12-4-3-11(16)9(2)13(12)17/h3-6H,7H2,1-2H3,(H2,18,19,20)	ZURGRGNGWXNRHC-UHFFFAOYSA-N	276711	2-[[1-(2,4-Difluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 651::US10233173, Example 651	Retinoic acid receptor RXR-alpha	Homo sapiens		 262					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276711&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309913	378158376							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525019	FC(F)c1c(F)ccc(c1F)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C15H8F7N5O/c16-9-1-2-10(12(17)11(9)13(18)19)27-5-8(25-26-27)6-28-14-23-3-7(4-24-14)15(20,21)22/h1-5,13H,6H2	XUHMPUWJQJDJAO-UHFFFAOYSA-N	276712	2-[[1-[3-(Difluoromethyl)-2,4-difluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 652::US10233173, Example 652	Retinoic acid receptor RXR-alpha	Homo sapiens		 112					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276712&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309917	378158377							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525020	Cc1cc(c(F)cc1F)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C14H10ClF2N5O/c1-8-2-13(12(17)3-11(8)16)22-6-10(20-21-22)7-23-14-18-4-9(15)5-19-14/h2-6H,7H2,1H3	SLIOCPNJPBDUDL-UHFFFAOYSA-N	276713	5-Chloro-2-[[1-(2,4-difluoro-5-methyl-phenyl)triazol-4-::US10071988, Example 653::US10233173, Example 653	Retinoic acid receptor RXR-alpha	Homo sapiens		 1490					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276713&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309928	378158378							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525021	Cc1cnc(OCc2cn(nn2)-c2cc(C)c(F)cc2F)nc1	InChI=1S/C15H13F2N5O/c1-9-5-18-15(19-6-9)23-8-11-7-22(21-20-11)14-3-10(2)12(16)4-13(14)17/h3-7H,8H2,1-2H3	IIAGUJZPDWLPOF-UHFFFAOYSA-N	276714	2-[[1-(2,4-Difluoro-5-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 654::US10233173, Example 654	Retinoic acid receptor RXR-alpha	Homo sapiens		 979					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276714&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309910	378158379							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525022	CCc1cnc(OCc2cn(nn2)-c2cc(C)c(F)cc2F)nc1	InChI=1S/C16H15F2N5O/c1-3-11-6-19-16(20-7-11)24-9-12-8-23(22-21-12)15-4-10(2)13(17)5-14(15)18/h4-8H,3,9H2,1-2H3	GODVVKGBJFPWQY-UHFFFAOYSA-N	276715	2-[[1-(2,4-Difluoro-5-methyl-phenyl)triazol-4-yl]methoxy]-5-ethyl-::US10071988, Example 655::US10233173, Example 655	Retinoic acid receptor RXR-alpha	Homo sapiens		 507					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276715&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309921	378158380							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525023	Cc1cc(c(F)cc1F)-n1cc(COc2ncc(cn2)C(F)F)nn1	InChI=1S/C15H11F4N5O/c1-8-2-13(12(17)3-11(8)16)24-6-10(22-23-24)7-25-15-20-4-9(5-21-15)14(18)19/h2-6,14H,7H2,1H3	QZRDDNIAXZJHTK-UHFFFAOYSA-N	276716	5-(Difluoromethyl)-2-[[1-(2,4-difluoro-5-methyl-phenyl)triazol-4-::US10071988, Example 656::US10233173, Example 656	Retinoic acid receptor RXR-alpha	Homo sapiens		 1510					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276716	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276716&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309922	378158381							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525024	Cc1cc(c(F)cc1F)-n1cc(COc2ncc(Cl)c(C)n2)nn1	InChI=1S/C15H12ClF2N5O/c1-8-3-14(13(18)4-12(8)17)23-6-10(21-22-23)7-24-15-19-5-11(16)9(2)20-15/h3-6H,7H2,1-2H3	HCTSEUCRBHEUFX-UHFFFAOYSA-N	276717	5-Chloro-2-[[1-(2,4-difluoro-5-methyl-phenyl)triazol-4-yl]methoxy]-4-::US10071988, Example 657::US10233173, Example 657	Retinoic acid receptor RXR-alpha	Homo sapiens		 781					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276717&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309919	378158382							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525025	Cc1cc(c(F)cc1F)-n1cc(COc2ncc(cn2)C2CC2)nn1	InChI=1S/C17H15F2N5O/c1-10-4-16(15(19)5-14(10)18)24-8-13(22-23-24)9-25-17-20-6-12(7-21-17)11-2-3-11/h4-8,11H,2-3,9H2,1H3	XWVBOQUOAZYJPS-UHFFFAOYSA-N	276718	5-Cyclopropyl-2-[[1-(2,4-difluoro-5-methyl-phenyl)triazol-4-::US10071988, Example 658::US10233173, Example 658	Retinoic acid receptor RXR-alpha	Homo sapiens		 424					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276718&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309918	378158383							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525026	Cc1cccc(n1)-n1cc(COc2ncc(Cl)cn2)nn1	InChI=1S/C13H11ClN6O/c1-9-3-2-4-12(17-9)20-7-11(18-19-20)8-21-13-15-5-10(14)6-16-13/h2-7H,8H2,1H3	GGQJKQNVNGDNLS-UHFFFAOYSA-N	276719	5-Chloro-2-[[1-(6-methyl-2-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 659::US10233173, Example 659	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276719&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309925	378158384							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525027	CCc1cnc(OCc2cn(nn2)-c2cccc(C)n2)nc1	InChI=1S/C15H16N6O/c1-3-12-7-16-15(17-8-12)22-10-13-9-21(20-19-13)14-6-4-5-11(2)18-14/h4-9H,3,10H2,1-2H3	KQTAJZUKGOKPAT-UHFFFAOYSA-N	276720	5-Ethyl-2-[[1-(6-methyl-2-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 660::US10233173, Example 660	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276720&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309929	378158385							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525028	Cc1cccc(n1)-n1cc(COc2ncc(Cl)c(C)n2)nn1	InChI=1S/C14H13ClN6O/c1-9-4-3-5-13(17-9)21-7-11(19-20-21)8-22-14-16-6-12(15)10(2)18-14/h3-7H,8H2,1-2H3	QGKFDHNFRJPQPN-UHFFFAOYSA-N	276721	5-Chloro-4-methyl-2-[[1-(6-methyl-2-pyridyl)triazol-4-::US10071988, Example 661::US10233173, Example 661	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276721&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309926	378158386							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525029	Cc1ccnc(c1)-n1cc(COc2ncc(C)cn2)nn1	InChI=1S/C14H14N6O/c1-10-3-4-15-13(5-10)20-8-12(18-19-20)9-21-14-16-6-11(2)7-17-14/h3-8H,9H2,1-2H3	AQNCJVAJSRCUSX-UHFFFAOYSA-N	276722	5-Methyl-2-[[1-(4-methyl-2-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 662::US10233173, Example 662	Retinoic acid receptor RXR-alpha	Homo sapiens		>2990					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276722&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309923	378158387							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525030	CCc1cnc(OCc2cn(nn2)-c2cc(C)ccn2)nc1	InChI=1S/C15H16N6O/c1-3-12-7-17-15(18-8-12)22-10-13-9-21(20-19-13)14-6-11(2)4-5-16-14/h4-9H,3,10H2,1-2H3	LTLHFUCBLZXGMO-UHFFFAOYSA-N	276723	5-Ethyl-2-[[1-(4-methyl-2-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 663::US10233173, Example 663	Retinoic acid receptor RXR-alpha	Homo sapiens		 2450					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276723&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309920	378158388							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525031	CCc1cnc(OCc2cn(nn2)-c2ccnc(C)c2)nc1	InChI=1S/C15H16N6O/c1-3-12-7-17-15(18-8-12)22-10-13-9-21(20-19-13)14-4-5-16-11(2)6-14/h4-9H,3,10H2,1-2H3	ZQQUIILIPGPDJW-UHFFFAOYSA-N	276724	5-Ethyl-2-[[1-(2-methyl-4-pyridyl)triazol-4-yl]methoxy]pyrimidine;::US10071988, Example 664::US10233173, Example 664	Retinoic acid receptor RXR-alpha	Homo sapiens		 169					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276724&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309932	378158389							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525032	CCc1cnc(OCc2cn(nn2)-c2ccnc(Br)c2)nc1	InChI=1S/C14H13BrN6O/c1-2-10-6-17-14(18-7-10)22-9-11-8-21(20-19-11)12-3-4-16-13(15)5-12/h3-8H,2,9H2,1H3	GXKAIBJAPAKSPE-UHFFFAOYSA-N	276725	2-[[1-(2-Bromo-4-pyridyl)triazol-4-yl]methoxy]-5-ethyl-pyrimidine;::US10071988, Example 665::US10233173, Example 665	Retinoic acid receptor RXR-alpha	Homo sapiens		 261					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276725&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309924	378158390							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525033	Cc1cnc(OCc2cn(nn2)-c2ccnc(c2)C(F)(F)F)nc1	InChI=1S/C14H11F3N6O/c1-9-5-19-13(20-6-9)24-8-10-7-23(22-21-10)11-2-3-18-12(4-11)14(15,16)17/h2-7H,8H2,1H3	BWXYCLNONZDABB-UHFFFAOYSA-N	276726	5-Methyl-2-[[1-[2-(trifluoromethyl)-4-pyridyl]triazol-4-::US10071988, Example 666::US10233173, Example 666	Retinoic acid receptor RXR-alpha	Homo sapiens		 668					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276726&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309930	378158391							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525034	CCc1cnc(OCc2cn(nn2)-c2ccnc(c2)C(F)(F)F)nc1	InChI=1S/C15H13F3N6O/c1-2-10-6-20-14(21-7-10)25-9-11-8-24(23-22-11)12-3-4-19-13(5-12)15(16,17)18/h3-8H,2,9H2,1H3	LVCFZMAGUYTWDJ-UHFFFAOYSA-N	276727	5-Ethyl-2-[[1-[2-(trifluoromethyl)-4-pyridyl]triazol-4-::US10071988, Example 667::US10233173, Example 667	Retinoic acid receptor RXR-alpha	Homo sapiens		 184					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276727&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309931	378158392							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525035	Cc1nc(OCc2cn(nn2)-c2ccc(s2)C(F)(F)F)ncc1F	InChI=1S/C13H9F4N5OS/c1-7-9(14)4-18-12(19-7)23-6-8-5-22(21-20-8)11-3-2-10(24-11)13(15,16)17/h2-5H,6H2,1H3	IVZYOHJJVZVNLL-UHFFFAOYSA-N	276728	5-Fluoro-4-methyl-2-((1-(5-(trifluoromethyl)thiophen-2-yl)-1H-1,2,3-::US10071988, Example 668::US10233173, Example 668	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276728&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302280	378158393							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525036	COc1cnc(OCc2cn(nn2)-c2ccc(s2)C(F)(F)F)nc1	InChI=1S/C13H10F3N5O2S/c1-22-9-4-17-12(18-5-9)23-7-8-6-21(20-19-8)11-3-2-10(24-11)13(14,15)16/h2-6H,7H2,1H3	PXUSAZKYODEGMC-UHFFFAOYSA-N	276729	5-Methoxy-2-((1-(5-(trifluoromethyl)thiophen-2-yl)-1H-1,2,3-triazol-4-::US10071988, Example 669::US10233173, Example 669	Retinoic acid receptor RXR-alpha	Homo sapiens		 4.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276729&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302244	378158394							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525037	FC(F)(F)c1ccc(s1)-n1cc(COc2ncc(cn2)C(F)(F)F)nn1	InChI=1S/C13H7F6N5OS/c14-12(15,16)7-3-20-11(21-4-7)25-6-8-5-24(23-22-8)10-2-1-9(26-10)13(17,18)19/h1-5H,6H2	IAQIUPJAANWHAS-UHFFFAOYSA-N	276730	5-(Trifluoromethyl)-2-((1-(5-(trifluoromethyl)thiophen-2-yl)-1H-1,2,3-::US10071988, Example 670::US10233173, Example 670	Retinoic acid receptor RXR-alpha	Homo sapiens		 63.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276730	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276730&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302269	378158395							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525038	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(NC3COC3)n2)nn1	InChI=1S/C17H15F3N6O3/c18-13-2-1-12(5-14(13)29-16(19)20)26-6-10(24-25-26)9-28-17-21-4-3-15(23-17)22-11-7-27-8-11/h1-6,11,16H,7-9H2,(H,21,22,23)	QWSCQGMPGLCISE-UHFFFAOYSA-N	276731	2-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 671::US10233173, Example 671	Retinoic acid receptor RXR-alpha	Homo sapiens		 126					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276731&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302392	378158396							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525039	FC(F)Oc1cc(ccc1F)-n1cc(COc2nccc(n2)-c2ccc[nH]2)nn1	InChI=1S/C18H13F3N6O2/c19-13-4-3-12(8-16(13)29-17(20)21)27-9-11(25-26-27)10-28-18-23-7-5-15(24-18)14-2-1-6-22-14/h1-9,17,22H,10H2	HJUJKOIKBNNFOF-UHFFFAOYSA-N	276732	2-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 681::US10233173, Example 681	Retinoic acid receptor RXR-alpha	Homo sapiens		 681					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276732&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302278	378158397							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525040	FC(F)c1cc(ccc1F)-n1cc(COc2nccc(NC3CC3)n2)nn1	InChI=1S/C17H15F3N6O/c18-14-4-3-12(7-13(14)16(19)20)26-8-11(24-25-26)9-27-17-21-6-5-15(23-17)22-10-1-2-10/h3-8,10,16H,1-2,9H2,(H,21,22,23)	LKVBJOIYEMEQTK-UHFFFAOYSA-N	276733	N-Cyclopropyl-2-((1-(3-(difluoromethyl)-4-fluorophenyl)-1H-1,2,3-::US10071988, Example 690::US10233173, Example 690	Retinoic acid receptor RXR-alpha	Homo sapiens		 8.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276733&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302258	378158398							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525041	CCNc1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C16H15F3N6O/c1-2-20-14-5-6-21-16(22-14)26-9-10-8-25(24-23-10)11-3-4-13(17)12(7-11)15(18)19/h3-8,15H,2,9H2,1H3,(H,20,21,22)	AKPPSQRZWXIXPS-UHFFFAOYSA-N	276734	N-Ethyl-2-((1-(3-(difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 691::US10233173, Example 691	Retinoic acid receptor RXR-alpha	Homo sapiens		 6.00					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276734&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302326	378158399							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525042	Cc1nccn1-c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C18H14F3N7O/c1-11-22-6-7-27(11)16-4-5-23-18(24-16)29-10-12-9-28(26-25-12)13-2-3-15(19)14(8-13)17(20)21/h2-9,17H,10H2,1H3	CKNXDGVNAQODGK-UHFFFAOYSA-N	276735	2-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 692::US10233173, Example 692	Retinoic acid receptor RXR-alpha	Homo sapiens		 1580					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276735&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302354	378158400							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525043	CC(F)(F)c1ccnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C16H12F5N5O/c1-16(20,21)13-4-5-22-15(23-13)27-8-9-7-26(25-24-9)10-2-3-12(17)11(6-10)14(18)19/h2-7,14H,8H2,1H3	UKONVMYCVDBGJN-UHFFFAOYSA-N	276736	4-(1,1-Difluoroethyl)-2-((1-(3-(difluoromethyl)-4-fluorophenyl)-1H-::US10071988, Example 696::US10233173, Example 696	Retinoic acid receptor RXR-alpha	Homo sapiens		 958					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276736&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309933	378158401							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525044	FC(F)c1cc(ccc1F)-n1cc(COc2nccc(n2)-n2cccn2)nn1	InChI=1S/C17H12F3N7O/c18-14-3-2-12(8-13(14)16(19)20)27-9-11(24-25-27)10-28-17-21-6-4-15(23-17)26-7-1-5-22-26/h1-9,16H,10H2	KIABAHMLRSKGKU-UHFFFAOYSA-N	276737	2-((1-(3-(Difluoromethyl)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 699::US10233173, Example 699	Retinoic acid receptor RXR-alpha	Homo sapiens		 389					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276737&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302253	378158402							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525045	CC(F)(F)c1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)F)nc1	InChI=1S/C16H12F5N5O/c1-16(20,21)9-5-22-15(23-6-9)27-8-10-7-26(25-24-10)11-2-3-13(17)12(4-11)14(18)19/h2-7,14H,8H2,1H3	QGSSQUDBESPXDX-UHFFFAOYSA-N	276738	5-(1,1-Difluoroethyl)-2-((1-(3-(difluoromethyl)-4-fluorophenyl)-1H-::US10071988, Example 701::US10233173, Example 701	Retinoic acid receptor RXR-alpha	Homo sapiens		 958					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276738&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130309934	378158403							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525046	CCOCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C17H16F3N5O3/c1-2-26-9-11-5-6-21-17(22-11)27-10-12-8-25(24-23-12)13-3-4-14(18)15(7-13)28-16(19)20/h3-8,16H,2,9-10H2,1H3	LUCRXRNUKFUASU-UHFFFAOYSA-N	276739	2-((1-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-1,2,3-triazol-4-::US10071988, Example 711::US10233173, Example 711	Retinoic acid receptor RXR-alpha	Homo sapiens		 43.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276739&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302316	378158404							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
525047	FC(F)COCc1ccnc(OCc2cn(nn2)-c2ccc(F)c(OC(F)F)c2)n1	InChI=1S/C17H14F5N5O3/c18-13-2-1-12(5-14(13)30-16(21)22)27-6-11(25-26-27)8-29-17-23-4-3-10(24-17)7-28-9-15(19)20/h1-6,15-16H,7-9H2	CRTQWQOBXDSBAH-UHFFFAOYSA-N	276740	4-((2,2-Difluoroethoxy)methyl)-2-((1-(3-(difluoromethoxy)-4-::US10071988, Example 716::US10233173, Example 716	Retinoic acid receptor RXR-alpha	Homo sapiens		 49.0					7.4	25.00 C	US Patent		10.7270/Q20Z7591		aid1795523	US10071988	Chen, G; Chrovian, CC; Coate, HR; Dvorak, CA; Gelin, CF; Hiscox, A; Letavic, MA; Rech, JC; Soyode-Johnson, A; Stenne, B; Wall, JL; Zhang, W	9/11/2018	12/21/2018	Janssen Pharmaceutica NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000270&target=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276740&enzyme=Retinoic+acid+receptor+RXR-alpha&column=ki&startPg=0&Increment=50&submit=Search			130302214	378158405							1	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT	1FBY,1FM6,1FM9,1G1U,1G5Y,1K74,1MV9,1MVC,1MZN,1R0N,1RDT,1XLS,1XV9,1XVP,1YNW,2ACL,2NLL,2P1T,2P1U,2P1V,2ZXZ,2ZY0,3DZU,3DZY,3E00,3E94,3FAL,3FC6,3FUG,3H0A,3KWY,3NSP,3NSQ,3OAP,3OZJ,3PCU,3R29,3R2A,3R5M,3UVV,4CN2,4CN3,4CN5,4CN7,4J5W,4J5X,4K4J,4K6I,4M8E,4M8H,4N5G,4N8R,4NQA,4OC7,4POH,4POJ,4PP3,4PP5,4RFW,4RMC,4RMD,4RME,4ZO1,4ZSH,5LYQ,5MJ5,5MK4,5MKJ,5MKU,5MMW,5TBP,5UAN,5Z12,6A5Y,6A5Z,6A60,6FBQ,6FBR,6HN6,6SJM,6STI,6XWG,6XWH,7A77,7B88,7B9O,7BK4,7NKE,7QAA,7UW2,7UW4,8HBM	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793	B3KY83 Q2NL52 Q2V504