BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
191251	CNC(=O)[C@@H](NC(=O)[C@@H]1CN(C(=O)c2cnn(Cc3ccccc3)c2)CC12CN(c1nnn[nH]1)C2)[C@@H](C)OCC1CCCCC1	InChI=1S/C31H42N10O4/c1-21(45-17-23-11-7-4-8-12-23)26(28(43)32-2)34-27(42)25-16-39(18-31(25)19-40(20-31)30-35-37-38-36-30)29(44)24-13-33-41(15-24)14-22-9-5-3-6-10-22/h3,5-6,9-10,13,15,21,23,25-26H,4,7-8,11-12,14,16-20H2,1-2H3,(H,32,43)(H,34,42)(H,35,36,37,38)	LBDLDNZGDGPRBX-UHFFFAOYSA-N	292808	US20260014146, Compound I-1	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292808&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123680	381613094							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191252	CNC(=O)[C@@H](NC(=O)[C@@H]1CN(C(=O)c2cnn(Cc3ccccc3)c2)CC12CN(c1ncco1)C2)[C@@H](C)OCC1CCCCC1	InChI=1S/C33H43N7O5/c1-23(45-19-25-11-7-4-8-12-25)28(30(42)34-2)37-29(41)27-18-38(20-33(27)21-39(22-33)32-35-13-14-44-32)31(43)26-15-36-40(17-26)16-24-9-5-3-6-10-24/h3,5-6,9-10,13-15,17,23,25,27-28H,4,7-8,11-12,16,18-22H2,1-2H3,(H,34,42)(H,37,41)	HTBMJGZVPYKTSX-UHFFFAOYSA-N	292809	US20260014146, Compound I-2	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292809&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122847	381613095							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191253	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1ncco1)C2)C(C)(C)O	InChI=1S/C28H39N5O6S/c1-18(38-15-27-6-4-19(5-7-27)39-16-27)22(26(2,3)36)31-23(34)20-11-32(24(35)21-10-29-17-40-21)12-28(20)13-33(14-28)25-30-8-9-37-25/h8-10,17-20,22,36H,4-7,11-16H2,1-3H3,(H,31,34)	GEKNAFPYFPOKBV-UHFFFAOYSA-N	292810	US20260014146, Compound I-3	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292810&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123456	381613096							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191254	C[C@@H](OCC1CCC(F)(F)CC1)[C@H](NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1ncco1)C2)C(C)(C)O	InChI=1S/C27H37F2N5O5S/c1-17(39-12-18-4-6-27(28,29)7-5-18)21(25(2,3)37)32-22(35)19-11-33(23(36)20-10-30-16-40-20)13-26(19)14-34(15-26)24-31-8-9-38-24/h8-10,16-19,21,37H,4-7,11-15H2,1-3H3,(H,32,35)	ALCZIUSKCABCGR-UHFFFAOYSA-N	292811	US20260014146, Compound I-4	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 5500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292811&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123252	381613097							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191255	CC(C)(O)C(NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1ncco1)C2)c1cccc(C2CCOCC2)n1	InChI=1S/C28H34N6O5S/c1-27(2,37)23(21-5-3-4-20(31-21)18-6-9-38-10-7-18)32-24(35)19-13-33(25(36)22-12-29-17-40-22)14-28(19)15-34(16-28)26-30-8-11-39-26/h3-5,8,11-12,17-19,23,37H,6-7,9-10,13-16H2,1-2H3,(H,32,35)	BVSFNBZMZNGFNS-UHFFFAOYSA-N	292812	US20260014146, Compound I-5	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292812&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123037	381613098							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191256	C[C@@H](OCC1CCC(F)(F)CC1)[C@H](NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1cc[nH]n1)C2)C(C)(C)O	InChI=1S/C27H38F2N6O4S/c1-17(39-12-18-4-7-27(28,29)8-5-18)22(25(2,3)38)32-23(36)19-11-34(24(37)20-10-30-16-40-20)13-26(19)14-35(15-26)21-6-9-31-33-21/h6,9-10,16-19,22,38H,4-5,7-8,11-15H2,1-3H3,(H,31,33)(H,32,36)	KUNHRXNEMNZYLL-UHFFFAOYSA-N	292813	US20260014146, Compound I-6	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292813&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123145	381613099							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191257	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2cccc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C36H51N5O4S/c1-24(45-19-25-11-6-4-7-12-25)30(34(44)39-15-8-5-9-16-39)38-32(42)27-18-40(29-14-10-13-28-31(29)46-23-37-28)20-36(27)21-41(22-36)33(43)26-17-35(26,2)3/h10,13-14,23-27,30H,4-9,11-12,15-22H2,1-3H3,(H,38,42)	JWWIVPWVNRCVEA-UHFFFAOYSA-N	292814	US20260014146, Compound I-7	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292814&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122877	381613100							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191258	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2cccc3scnc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C36H51N5O4S/c1-24(45-19-25-11-6-4-7-12-25)30(34(44)39-15-8-5-9-16-39)38-32(42)27-18-40(28-13-10-14-29-31(28)37-23-46-29)20-36(27)21-41(22-36)33(43)26-17-35(26,2)3/h10,13-14,23-27,30H,4-9,11-12,15-22H2,1-3H3,(H,38,42)	MNLNZDCPKINEKY-UHFFFAOYSA-N	292815	US20260014146, Compound I-8	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292815&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123820	381613101							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191259	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2nccc3[nH]ncc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C35H51N7O4/c1-23(46-19-24-10-6-4-7-11-24)29(33(45)40-14-8-5-9-15-40)38-31(43)27-18-41(30-25-17-37-39-28(25)12-13-36-30)20-35(27)21-42(22-35)32(44)26-16-34(26,2)3/h12-13,17,23-24,26-27,29H,4-11,14-16,18-22H2,1-3H3,(H,37,39)(H,38,43)	BYZOJMKHZBBNKH-UHFFFAOYSA-N	292816	US20260014146, Compound I-9	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292816&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122949	381613102							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191260	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2nccc3scnc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C35H50N6O4S/c1-23(45-18-24-10-6-4-7-11-24)28(33(44)39-14-8-5-9-15-39)38-31(42)26-17-40(30-29-27(12-13-36-30)46-22-37-29)19-35(26)20-41(21-35)32(43)25-16-34(25,2)3/h12-13,22-26,28H,4-11,14-21H2,1-3H3,(H,38,42)	XEHIOPGNFQJZDH-UHFFFAOYSA-N	292817	US20260014146, Compound I-10	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292817&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123106	381613103							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191261	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2nccc3cn[nH]c23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C35H51N7O4/c1-23(46-19-24-10-6-4-7-11-24)28(33(45)40-14-8-5-9-15-40)38-31(43)27-18-41(30-29-25(12-13-36-30)17-37-39-29)20-35(27)21-42(22-35)32(44)26-16-34(26,2)3/h12-13,17,23-24,26-28H,4-11,14-16,18-22H2,1-3H3,(H,37,39)(H,38,43)	DZKFJQWPZWBCIW-UHFFFAOYSA-N	292818	US20260014146, Compound I-12	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292818&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123712	381613104							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191262	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2cccc3[nH]ncc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C36H52N6O4/c1-24(46-20-25-11-6-4-7-12-25)31(34(45)40-15-8-5-9-16-40)38-32(43)28-19-41(30-14-10-13-29-26(30)18-37-39-29)21-36(28)22-42(23-36)33(44)27-17-35(27,2)3/h10,13-14,18,24-25,27-28,31H,4-9,11-12,15-17,19-23H2,1-3H3,(H,37,39)(H,38,43)	ILAQPMWJBLTANX-UHFFFAOYSA-N	292819	US20260014146, Compound I-13	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 5500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292819&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123370	381613105							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191263	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2cccc3[nH]ccc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C37H53N5O4/c1-25(46-21-26-11-6-4-7-12-26)32(35(45)40-17-8-5-9-18-40)39-33(43)29-20-41(31-14-10-13-30-27(31)15-16-38-30)22-37(29)23-42(24-37)34(44)28-19-36(28,2)3/h10,13-16,25-26,28-29,32,38H,4-9,11-12,17-24H2,1-3H3,(H,39,43)	LPNNAHPCRDQGIN-UHFFFAOYSA-N	292820	US20260014146, Compound I-14	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292820&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123915	381613106							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191264	C[C@@H](OCC1CCCCC1)[C@H](NC(=O)[C@@H]1CN(c2nccc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCCC1	InChI=1S/C35H50N6O4S/c1-23(45-18-24-10-6-4-7-11-24)28(33(44)39-14-8-5-9-15-39)38-31(42)26-17-40(30-29-27(12-13-36-30)37-22-46-29)19-35(26)20-41(21-35)32(43)25-16-34(25,2)3/h12-13,22-26,28H,4-11,14-21H2,1-3H3,(H,38,42)	URDMSPMLLDRFON-UHFFFAOYSA-N	292821	US20260014146, Compound I-15	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292821&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123923	381613107							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191265	C[C@@H](OCC12CCC(CC1)OC2)C(NC(=O)[C@@H]1CN(c2cccc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(C)(C)O	InChI=1S/C34H48N4O5S/c1-21(42-18-33-11-9-22(10-12-33)43-19-33)28(32(4,5)41)36-29(39)24-14-37(26-8-6-7-25-27(26)44-20-35-25)15-34(24)16-38(17-34)30(40)23-13-31(23,2)3/h6-8,20-24,28,41H,9-19H2,1-5H3,(H,36,39)	JXQBDVUAJBSDLK-UHFFFAOYSA-N	292822	US20260014146, Compound I-16	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292822&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123541	381613108							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191266	C[C@@H](OCC12CCC(CC1)OC2)C(NC(=O)[C@@H]1CN(c2cccc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(C)(C)O	InChI=1S/C34H48N4O5S/c1-21(42-18-33-11-9-22(10-12-33)43-19-33)28(32(4,5)41)36-29(39)24-14-37(26-8-6-7-25-27(26)44-20-35-25)15-34(24)16-38(17-34)30(40)23-13-31(23,2)3/h6-8,20-24,28,41H,9-19H2,1-5H3,(H,36,39)	JXQBDVUAJBSDLK-UHFFFAOYSA-N	292823	US20260014146, Compound I-16-1	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292823&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123147	381613109							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191267	COC[C@H]1CCCN(C(=O)[C@H](NC(=O)[C@@H]2CN(c3nc(C(F)(F)F)cs3)CC23CN(C(=O)[C@H]2CC2(C)C)C3)[C@@H](C)OCC23CCC(CC2)OC3)C1	InChI=1S/C36H52F3N5O6S/c1-22(49-20-34-9-7-24(8-10-34)50-21-34)28(31(47)42-11-5-6-23(13-42)15-48-4)41-29(45)26-14-43(32-40-27(16-51-32)36(37,38)39)17-35(26)18-44(19-35)30(46)25-12-33(25,2)3/h16,22-26,28H,5-15,17-21H2,1-4H3,(H,41,45)	YBGICVUVTXOCGY-UHFFFAOYSA-N	292824	US20260014146, Compound I-17	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292824&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122840	381613110							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191268	COC[C@H]1CCCN(C(=O)[C@H](NC(=O)[C@@H]2CN(c3nc(C(F)(F)F)cs3)CC23CN(C(=O)[C@H]2CC2(C)C)C3)[C@@H](C)OCC23CCC(CC2)OC3)C1	InChI=1S/C36H52F3N5O6S/c1-22(49-20-34-9-7-24(8-10-34)50-21-34)28(31(47)42-11-5-6-23(13-42)15-48-4)41-29(45)26-14-43(32-40-27(16-51-32)36(37,38)39)17-35(26)18-44(19-35)30(46)25-12-33(25,2)3/h16,22-26,28H,5-15,17-21H2,1-4H3,(H,41,45)	YBGICVUVTXOCGY-UHFFFAOYSA-N	292825	US20260014146, Compound I-17-1	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292825&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122955	381613111							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191269	COC[C@H]1CCCN(C(=O)[C@@H](NC(=O)[C@@H]2CN(c3cc(F)cc4ncsc34)CC23CN(C(=O)[C@H]2CC2(C)C)C3)[C@@H](C)OCC23CCC(CC2)OC3)C1	InChI=1S/C39H54FN5O6S/c1-24(50-21-38-9-7-27(8-10-38)51-22-38)32(36(48)43-11-5-6-25(15-43)17-49-4)42-34(46)29-16-44(31-13-26(40)12-30-33(31)52-23-41-30)18-39(29)19-45(20-39)35(47)28-14-37(28,2)3/h12-13,23-25,27-29,32H,5-11,14-22H2,1-4H3,(H,42,46)	HPLSDTCAMDCJSB-UHFFFAOYSA-N	292826	US20260014146, Compound I-18	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 55							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292826&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123367	381613112							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191270	COC[C@H]1CCCN(C(=O)[C@@H](NC(=O)[C@@H]2CN(c3cc(F)cc4ncsc34)CC23CN(C(=O)[C@H]2CC2(C)C)C3)[C@@H](C)OCC23CCC(CC2)OC3)C1	InChI=1S/C39H54FN5O6S/c1-24(50-21-38-9-7-27(8-10-38)51-22-38)32(36(48)43-11-5-6-25(15-43)17-49-4)42-34(46)29-16-44(31-13-26(40)12-30-33(31)52-23-41-30)18-39(29)19-45(20-39)35(47)28-14-37(28,2)3/h12-13,23-25,27-29,32H,5-11,14-22H2,1-4H3,(H,42,46)	HPLSDTCAMDCJSB-UHFFFAOYSA-N	292827	US20260014146, Compound I-18-1	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292827&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124129210	381613113							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191271	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2nccc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC2(CC1)COC2	InChI=1S/C38H52N6O6S/c1-24(49-21-36-7-4-25(5-8-36)50-22-36)29(34(47)42-12-9-37(10-13-42)19-48-20-37)41-32(45)27-15-43(31-30-28(6-11-39-31)40-23-51-30)16-38(27)17-44(18-38)33(46)26-14-35(26,2)3/h6,11,23-27,29H,4-5,7-10,12-22H2,1-3H3,(H,41,45)	SZHYLUXJXKHMHL-UHFFFAOYSA-N	292828	US20260014146, Compound I-19	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 5500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292828&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124129212	381613114							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191272	COC[C@H]1CCCN(C(=O)[C@@H](NC(=O)[C@@H]2CN(c3cc(O)cc4ncsc34)CC23CN(C(=O)[C@H]2CC2(C)C)C3)[C@@H](C)OCC23CCC(CC2)OC3)C1	InChI=1S/C39H55N5O7S/c1-24(50-21-38-9-7-27(8-10-38)51-22-38)32(36(48)42-11-5-6-25(15-42)17-49-4)41-34(46)29-16-43(31-13-26(45)12-30-33(31)52-23-40-30)18-39(29)19-44(20-39)35(47)28-14-37(28,2)3/h12-13,23-25,27-29,32,45H,5-11,14-22H2,1-4H3,(H,41,46)	MLKXBDRZXGJZLY-UHFFFAOYSA-N	292829	US20260014146, Compound I-20	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292829&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124129213	381613115							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191273	COC[C@H]1CCCN(C(=O)[C@@H](NC(=O)[C@@H]2CN(c3cc(C(F)(F)F)cc4ncsc34)CC23CN(C(=O)[C@H]2CC2(C)C)C3)[C@@H](C)OCC23CCC(CC2)OC3)C1	InChI=1S/C40H54F3N5O6S/c1-24(53-21-38-9-7-27(8-10-38)54-22-38)32(36(51)46-11-5-6-25(15-46)17-52-4)45-34(49)29-16-47(18-39(29)19-48(20-39)35(50)28-14-37(28,2)3)31-13-26(40(41,42)43)12-30-33(31)55-23-44-30/h12-13,23-25,27-29,32H,5-11,14-22H2,1-4H3,(H,45,49)	BXPSIFMQNFYRMH-UHFFFAOYSA-N	292830	US20260014146, Compound I-21	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292830&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123164	381613116							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191274	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2cccc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N(C)C	InChI=1S/C34H47N5O5S/c1-21(43-18-33-11-9-22(10-12-33)44-19-33)27(31(42)37(4)5)36-29(40)24-14-38(26-8-6-7-25-28(26)45-20-35-25)15-34(24)16-39(17-34)30(41)23-13-32(23,2)3/h6-8,20-24,27H,9-19H2,1-5H3,(H,36,40)	VIPLEWVLUXLDEK-UHFFFAOYSA-N	292831	US20260014146, Compound I-22	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 5500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292831&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124129632	381613117							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191275	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2nccc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N(C)C	InChI=1S/C33H46N6O5S/c1-20(43-17-32-9-6-21(7-10-32)44-18-32)25(30(42)37(4)5)36-28(40)23-13-38(27-26-24(8-11-34-27)35-19-45-26)14-33(23)15-39(16-33)29(41)22-12-31(22,2)3/h8,11,19-23,25H,6-7,9-10,12-18H2,1-5H3,(H,36,40)	SKADZBOXHSPPDF-UHFFFAOYSA-N	292832	US20260014146, Compound I-23	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 5500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292832&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124129633	381613118							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191276	COC[C@H]1CCCN(C(=O)[C@@H](NC(=O)[C@@H]2CN(c3n[nH]c4ncccc34)CC23CN(C(=O)[C@H]2CC2(C)C)C3)[C@@H](C)OCC23CCC(CC2)OC3)C1	InChI=1S/C38H55N7O6/c1-24(50-22-37-11-9-26(10-12-37)51-23-37)30(35(48)43-14-6-7-25(16-43)18-49-4)40-33(46)29-17-44(32-27-8-5-13-39-31(27)41-42-32)19-38(29)20-45(21-38)34(47)28-15-36(28,2)3/h5,8,13,24-26,28-30H,6-7,9-12,14-23H2,1-4H3,(H,40,46)(H,39,41,42)	GUBFNHAZJGSUPB-UHFFFAOYSA-N	292833	US20260014146, Compound I-24	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292833&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123494	381613119							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191277	CC(OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CC2(CCOCC2)C1	InChI=1S/C37H51N7O6S/c1-23(49-19-36-6-4-24(5-7-36)50-20-36)27(33(47)43-14-35(15-43)8-10-48-11-9-35)41-31(45)26-13-42(30-28-29(38-21-39-30)40-22-51-28)16-37(26)17-44(18-37)32(46)25-12-34(25,2)3/h21-27H,4-20H2,1-3H3,(H,41,45)	XGQZXJGWIAYPEI-UHFFFAOYSA-N	292834	US20260014146, Compound I-25	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292834&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123439	381613120							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191278	CC(OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CC2(CCOCC2)C1	InChI=1S/C37H51N7O6S/c1-23(49-19-36-6-4-24(5-7-36)50-20-36)27(33(47)43-14-35(15-43)8-10-48-11-9-35)41-31(45)26-13-42(30-28-29(38-21-39-30)40-22-51-28)16-37(26)17-44(18-37)32(46)25-12-34(25,2)3/h21-27H,4-20H2,1-3H3,(H,41,45)	XGQZXJGWIAYPEI-UHFFFAOYSA-N	292834	US20260014146, Compound I-25	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292834&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123439	381613120							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191279	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCCC2(COC2)C1	InChI=1S/C37H51N7O6S/c1-23(49-19-35-8-5-24(6-9-35)50-20-35)27(33(47)42-10-4-7-36(13-42)17-48-18-36)41-31(45)26-12-43(30-28-29(38-21-39-30)40-22-51-28)14-37(26)15-44(16-37)32(46)25-11-34(25,2)3/h21-27H,4-20H2,1-3H3,(H,41,45)	UBAKPYDICHEASD-UHFFFAOYSA-N	292835	US20260014146, Compound I-26	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292835&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123298	381613121							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191280	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1ncccn1)C2)C(=O)N1CCC(C(F)(F)F)CC1	InChI=1S/C33H42F3N7O5S/c1-21(47-18-31-7-3-23(4-8-31)48-19-31)26(29(46)41-11-5-22(6-12-41)33(34,35)36)40-27(44)24-14-42(28(45)25-13-37-20-49-25)15-32(24)16-43(17-32)30-38-9-2-10-39-30/h2,9-10,13,20-24,26H,3-8,11-12,14-19H2,1H3,(H,40,44)	GTVXSPLPMOQDGZ-UHFFFAOYSA-N	292836	US20260014146, Compound I-27	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 5500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292836&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124129634	381613122							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191281	CNC(=O)[C@@H](NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1nc3ccccc3o1)C2)[C@@H](C)OCC12CCC(CC1)OC2	InChI=1S/C31H38N6O6S/c1-19(41-16-30-9-7-20(8-10-30)42-17-30)25(27(39)32-2)35-26(38)21-12-36(28(40)24-11-33-18-44-24)13-31(21)14-37(15-31)29-34-22-5-3-4-6-23(22)43-29/h3-6,11,18-21,25H,7-10,12-17H2,1-2H3,(H,32,39)(H,35,38)	WNTSNIGBPBWLOU-UHFFFAOYSA-N	292837	US20260014146, Compound I-28	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292837&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124129239	381613123							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191282	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(OC(F)(F)F)CC1	InChI=1S/C36H48F3N7O6S/c1-21(50-17-34-8-4-22(5-9-34)51-18-34)26(32(49)44-10-6-23(7-11-44)52-36(37,38)39)43-30(47)25-13-45(29-27-28(40-19-41-29)42-20-53-27)14-35(25)15-46(16-35)31(48)24-12-33(24,2)3/h19-26H,4-18H2,1-3H3,(H,43,47)	WQYYTWIUSICPTL-UHFFFAOYSA-N	292839	US20260014146, Compound I-29-1	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 55							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292839&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122983	381613124							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191283	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(OC(F)(F)F)CC1	InChI=1S/C36H48F3N7O6S/c1-21(50-17-34-8-4-22(5-9-34)51-18-34)26(32(49)44-10-6-23(7-11-44)52-36(37,38)39)43-30(47)25-13-45(29-27-28(40-19-41-29)42-20-53-27)14-35(25)15-46(16-35)31(48)24-12-33(24,2)3/h19-26H,4-18H2,1-3H3,(H,43,47)	WQYYTWIUSICPTL-UHFFFAOYSA-N	292840	US20260014146, Compound I-29	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 55							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292840&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123297	381613125							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191284	C[C@@H](OCC12CCC(CC1)OC2)C(NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(C(F)(F)F)CC1	InChI=1S/C36H48F3N7O5S/c1-21(50-17-34-8-4-23(5-9-34)51-18-34)26(32(49)44-10-6-22(7-11-44)36(37,38)39)43-30(47)25-13-45(29-27-28(40-19-41-29)42-20-52-27)14-35(25)15-46(16-35)31(48)24-12-33(24,2)3/h19-26H,4-18H2,1-3H3,(H,43,47)	LSTBZTMVTIPSQD-UHFFFAOYSA-N	292841	US20260014146, Compound I-30	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 55							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292841&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123424	381613126							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191285	C[C@@H](OCC12CCC(CC1)OC2)C(NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(C(F)(F)F)CC1	InChI=1S/C36H48F3N7O5S/c1-21(50-17-34-8-4-23(5-9-34)51-18-34)26(32(49)44-10-6-22(7-11-44)36(37,38)39)43-30(47)25-13-45(29-27-28(40-19-41-29)42-20-52-27)14-35(25)15-46(16-35)31(48)24-12-33(24,2)3/h19-26H,4-18H2,1-3H3,(H,43,47)	LSTBZTMVTIPSQD-UHFFFAOYSA-N	292842	US20260014146, Compound I-30-1	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 55							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292842&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123236	381613127							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191286	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1cc[nH]n1)C2)C(C)(C)O	InChI=1S/C28H40N6O5S/c1-18(38-15-27-7-4-19(5-8-27)39-16-27)23(26(2,3)37)31-24(35)20-11-33(25(36)21-10-29-17-40-21)12-28(20)13-34(14-28)22-6-9-30-32-22/h6,9-10,17-20,23,37H,4-5,7-8,11-16H2,1-3H3,(H,30,32)(H,31,35)	MRHAJEAYUWCJSE-UHFFFAOYSA-N	292843	US20260014146, Compound I-31	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292843&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123146	381613128							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191287	CNC(=O)C(NC(=O)[C@@H]1CN(C(=O)c2cncs2)CC12CN(c1nc(C(F)(F)F)co1)C2)[C@@H](C)OCC12CCC(CC1)OC2	InChI=1S/C28H35F3N6O6S/c1-16(42-13-26-5-3-17(4-6-26)43-14-26)21(23(39)32-2)35-22(38)18-8-36(24(40)19-7-33-15-44-19)10-27(18)11-37(12-27)25-34-20(9-41-25)28(29,30)31/h7,9,15-18,21H,3-6,8,10-14H2,1-2H3,(H,32,39)(H,35,38)	HHDXUAZYMIVRJV-UHFFFAOYSA-N	292844	US20260014146, Compound I-32	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292844	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292844&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123761	381613129							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191288	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]1CN(c2cc(F)cc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(c2ccncc2)CC1	InChI=1S/C42H53FN6O5S/c1-26(53-23-41-10-4-30(5-11-41)54-24-41)35(39(52)47-14-8-28(9-15-47)27-6-12-44-13-7-27)46-37(50)32-19-48(34-17-29(43)16-33-36(34)55-25-45-33)20-42(32)21-49(22-42)38(51)31-18-40(31,2)3/h6-7,12-13,16-17,25-26,28,30-32,35H,4-5,8-11,14-15,18-24H2,1-3H3,(H,46,50)	PLGYSBBOPFQFLX-UHFFFAOYSA-N	292845	US20260014146, Compound I-33	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		<10							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292845&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123563	381613130							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191289	C[C@@H](OCC1(C(F)(F)F)CC1)[C@H](NC(=O)C1CN(c2cc(F)cc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(c2ccncc2)CC1	InChI=1S/C39H46F4N6O4S/c1-23(53-21-38(8-9-38)39(41,42)43)31(35(52)47-12-6-25(7-13-47)24-4-10-44-11-5-24)46-33(50)28-17-48(30-15-26(40)14-29-32(30)54-22-45-29)18-37(28)19-49(20-37)34(51)27-16-36(27,2)3/h4-5,10-11,14-15,22-23,25,27-28,31H,6-9,12-13,16-21H2,1-3H3,(H,46,50)	WWDYIVUUZNFRTG-UHFFFAOYSA-N	292846	US20260014146, Compound I-34	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292846	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292846&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122907	381613131							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191290	C[C@@H](OCC1(CO)CC=CCC1)C(NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(OC(F)(F)F)CC1	InChI=1S/C36H48F3N7O6S/c1-22(51-19-34(18-47)9-5-4-6-10-34)26(32(50)44-11-7-23(8-12-44)52-36(37,38)39)43-30(48)25-14-45(29-27-28(40-20-41-29)42-21-53-27)15-35(25)16-46(17-35)31(49)24-13-33(24,2)3/h4-5,20-26,47H,6-19H2,1-3H3,(H,43,48)	SMYBAWIMOXBNFL-UHFFFAOYSA-N	292847	US20260014146, Compound I-35	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 55							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292847	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292847&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124122893	381613132							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191291	C[C@@H](OCC1(CO)CC=CCC1)[C@H](NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CCC(C(F)(F)F)CC1	InChI=1S/C36H48F3N7O5S/c1-22(51-19-34(18-47)9-5-4-6-10-34)26(32(50)44-11-7-23(8-12-44)36(37,38)39)43-30(48)25-14-45(29-27-28(40-20-41-29)42-21-52-27)15-35(25)16-46(17-35)31(49)24-13-33(24,2)3/h4-5,20-26,47H,6-19H2,1-3H3,(H,43,48)	XDMKSBRPKRLLSV-UHFFFAOYSA-N	292848	US20260014146, Compound I-36	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 55							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292848&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123357	381613133							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191292	C[C@@H](OCC1(CO)CC=CCC1)[C@H](NC(=O)[C@@H]1CN(c2ncnc3ncsc23)CC12CN(C(=O)[C@H]1CC1(C)C)C2)C(=O)N1CC2(CCOCC2)C1	InChI=1S/C37H51N7O6S/c1-24(50-21-36(20-45)7-5-4-6-8-36)27(33(48)43-15-35(16-43)9-11-49-12-10-35)41-31(46)26-14-42(30-28-29(38-22-39-30)40-23-51-28)17-37(26)18-44(19-37)32(47)25-13-34(25,2)3/h4-5,22-27,45H,6-21H2,1-3H3,(H,41,46)	PGBNEGCOFZRBFQ-UHFFFAOYSA-N	292849	US20260014146, Compound I-37	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 550							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292849&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123755	381613134							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191293	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)[C@@H]5CN(c3cc(F)cc4nccnc34)CC57CN(C(=O)C6(C(F)(F)F)CC6)C7)C(=O)N9CCC(c8nccs8)CC9	InChI=1S/C40H49F4N7O5S/c1-24(56-23-37(2)7-3-27(52)4-8-37)31(35(54)49-14-5-25(6-15-49)34-47-13-16-57-34)48-33(53)28-19-50(30-18-26(41)17-29-32(30)46-12-11-45-29)20-38(28)21-51(22-38)36(55)39(9-10-39)40(42,43)44/h11-13,16-18,24-25,27-28,31,52H,3-10,14-15,19-23H2,1-2H3,(H,48,53)	WHRCYWOWFWZLOZ-UHFFFAOYSA-N	292850	US20260014146, Compound I-44	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		<5000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292850&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123271	381613135							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191294	C[C@@H](OCC12CCC(CC1)CO2)[C@H](NC(=O)[C@@H]5CN(c3cccc4nc(O)cnc34)CC57CN(C(=O)C6(C(F)(F)F)CC6)C7)C(=O)N9CCC(c8nccs8)CC9	InChI=1S/C40H50F3N7O6S/c1-24(56-23-37(2)10-6-26(51)7-11-37)31(35(54)48-15-8-25(9-16-48)34-44-14-17-57-34)47-33(53)27-19-49(29-5-3-4-28-32(29)45-18-30(52)46-28)20-38(27)21-50(22-38)36(55)39(12-13-39)40(41,42)43/h3-5,14,17-18,24-27,31,51H,6-13,15-16,19-23H2,1-2H3,(H,46,52)(H,47,53)	WNTQRYIOABZWRX-UHFFFAOYSA-N	292851	US20260014146, Compound I-45	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292851&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123401	381613136							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191295	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)C5CN(c3cc(F)cc4ncsc34)CC57CN(C(=O)C6(C(F)(F)F)CC6)C7)C(=O)N8CCC9(CC8)COC9	InChI=1S/C38H49F4N5O6S/c1-23(53-19-34(2)5-3-25(48)4-6-34)29(32(50)45-11-9-35(10-12-45)20-52-21-35)44-31(49)26-15-46(28-14-24(39)13-27-30(28)54-22-43-27)16-36(26)17-47(18-36)33(51)37(7-8-37)38(40,41)42/h13-14,22-23,25-26,29,48H,3-12,15-21H2,1-2H3,(H,44,49)	QUNCIKFPGQHLRD-UHFFFAOYSA-N	292852	US20260014146, Compound I-46	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292852&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123795	381613137							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191296	C[C@@H](OCC12CCC(CC1)OC2)[C@@H](COC4CCC(c3ccc(C(=O)O)cc3)CC4)NC(=O)C7CN(c5cc(F)cc6ncsc56)CC79CN(C(=O)C8(C(F)(F)F)CC8)C9	InChI=1S/C44H54F4N4O7S/c1-26(59-24-41(2)13-11-31(53)12-14-41)35(20-58-32-9-7-28(8-10-32)27-3-5-29(6-4-27)39(55)56)50-38(54)33-19-51(36-18-30(45)17-34-37(36)60-25-49-34)21-42(33)22-52(23-42)40(57)43(15-16-43)44(46,47)48/h3-6,17-18,25-26,28,31-33,35,53H,7-16,19-24H2,1-2H3,(H,50,54)(H,55,56)	RGVHFWOVGJLEDN-UHFFFAOYSA-N	292853	US20260014146, Compound I-47	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292853&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123416	381613138							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191297	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)C5CN(c3cc(F)cc4ncsc34)CC57CN(C(=O)C6(C(F)(F)F)CC6)C7)C(=O)N9CCC(c8nccs8)CC9	InChI=1S/C39H48F4N6O5S2/c1-23(54-21-36(2)7-3-26(50)4-8-36)30(34(52)47-12-5-24(6-13-47)33-44-11-14-55-33)46-32(51)27-17-48(29-16-25(40)15-28-31(29)56-22-45-28)18-37(27)19-49(20-37)35(53)38(9-10-38)39(41,42)43/h11,14-16,22-24,26-27,30,50H,3-10,12-13,17-21H2,1-2H3,(H,46,51)	UURCPWUBOLQUPJ-UHFFFAOYSA-N	292854	US20260014146, Compound I-48	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		<5000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292854	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292854&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123916	381613139							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191298	C[C@@H](OCC12CCC(CC1)OC2)[C@@H](COc3ccccc3C(=O)O)NC(=O)C6CN(c4cc(F)cc5ncsc45)CC68CN(C(=O)C7(C(F)(F)F)CC7)C8	InChI=1S/C38H44F4N4O7S/c1-22(53-20-35(2)9-7-24(47)8-10-35)28(16-52-30-6-4-3-5-25(30)33(49)50)44-32(48)26-15-45(29-14-23(39)13-27-31(29)54-21-43-27)17-36(26)18-46(19-36)34(51)37(11-12-37)38(40,41)42/h3-6,13-14,21-22,24,26,28,47H,7-12,15-20H2,1-2H3,(H,44,48)(H,49,50)	IZFFEOFPDBRHDL-UHFFFAOYSA-N	292855	US20260014146, Compound I-49	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292855	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292855&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123845	381613140							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191299	COc8ccc(S(=O)(=O)NC(=O)[C@@H](NC(=O)C3CN(c1cc(F)cc2ncsc12)CC35CN(C(=O)C4(C(F)(F)F)CC4)C5)[C@@H](C)OCC67CCC(CC6)OC7)cc8	InChI=1S/C38H45F4N5O8S2/c1-22(55-20-35(2)10-8-24(48)9-11-35)30(33(50)45-57(52,53)26-6-4-25(54-3)5-7-26)44-32(49)27-16-46(29-15-23(39)14-28-31(29)56-21-43-28)17-36(27)18-47(19-36)34(51)37(12-13-37)38(40,41)42/h4-7,14-15,21-22,24,27,30,48H,8-13,16-20H2,1-3H3,(H,44,49)(H,45,50)	SKLVPGMMVAYAHR-UHFFFAOYSA-N	292856	US20260014146, Compound I-50	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 7500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292856	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292856&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123144	381613141							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191300	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)C5CN(c3cc(F)cc4ncsc34)CC57CN(C(=O)C6(C(F)(F)F)CC6)C7)C(=O)NS(=O)(=O)c8ccc(F)cc8F	InChI=1S/C37H41F6N5O7S2/c1-20(55-18-34(2)7-5-23(49)6-8-34)29(32(51)46-57(53,54)28-4-3-21(38)11-25(28)40)45-31(50)24-14-47(27-13-22(39)12-26-30(27)56-19-44-26)15-35(24)16-48(17-35)33(52)36(9-10-36)37(41,42)43/h3-4,11-13,19-20,23-24,29,49H,5-10,14-18H2,1-2H3,(H,45,50)(H,46,51)	RHPAGFPAOWXQDV-UHFFFAOYSA-N	292857	US20260014146, Compound I-51	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 7500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292857	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292857&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123620	381613142							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191301	C[C@@H](OCC12CCC(CC1)OC2)[C@H](NC(=O)C5CN(c3cc(F)cc4ncoc34)CC57CN(C(=O)C6(C(F)(F)F)CC6)C7)C(=O)N9CCC(c8nccs8)CC9	InChI=1S/C39H48F4N6O6S/c1-23(54-21-36(2)7-3-26(50)4-8-36)30(34(52)47-12-5-24(6-13-47)33-44-11-14-56-33)46-32(51)27-17-48(29-16-25(40)15-28-31(29)55-22-45-28)18-37(27)19-49(20-37)35(53)38(9-10-38)39(41,42)43/h11,14-16,22-24,26-27,30,50H,3-10,12-13,17-21H2,1-2H3,(H,46,51)	MUJJLIKCXHGUPU-UHFFFAOYSA-N	292858	US20260014146, Compound I-52	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		 7500							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292858	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292858&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123824	381613143							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																						
191302	C[C@@H](OCC12CCC(CC1)OC2)[C@@H](CO[C@@H]4CC[C@@H](c3ccccc3C(=O)O)CC4)NC(=O)C7CN(c5cc(F)cc6ncsc56)CC79CN(C(=O)C8(C(F)(F)F)CC8)C9	InChI=1S/C44H54F4N4O7S/c1-26(59-24-41(2)13-11-29(53)12-14-41)35(20-58-30-9-7-27(8-10-30)31-5-3-4-6-32(31)39(55)56)50-38(54)33-19-51(36-18-28(45)17-34-37(36)60-25-49-34)21-42(33)22-52(23-42)40(57)43(15-16-43)44(46,47)48/h3-6,17-18,25-27,29-30,33,35,53H,7-16,19-24H2,1-2H3,(H,50,54)(H,55,56)	AZLZNTCOOFDOEP-UHFFFAOYSA-N	292859	US20260014146, Compound I-53	Cyclin-dependent kinase 2/G1/S-specific cyclin-E1	Homo sapiens		>10000							US Patent		10.7270/Q27S7TKX			US20260014146	KIRMAN, LC; SCHWARTZ, CE; BLAISDELL, TP	1/15/2026	5/28/2026	Cedilla Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=292859	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=81&target=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=292859&enzyme=Cyclin-dependent+kinase+2%2FG1%2FS-specific+cyclin-E1&column=ki&startPg=0&Increment=50&submit=Search			124123650	381613144							2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL	9OB6,9OB5,9OB4,9OB3,9OB2,9FR2,9BJC,8B54,7QHL,7B7S,7ACK,6RIJ,6JGM,6INL,6GVA,5LMK,5L2W,3DOG,3DDQ,3DDP,2G9X,2CCI,2CCH,1QMZ,1P5E,1GY3,9QJJ,9QCX,9QCV,9NYR,9NYQ,9I9K,9I9J,9GP3,9GOP,9D0X,9D0W,9D0V,9D0U,8VQ4,8VQ3,8ROZ,8OY2,8OR4,8OR0,8FP5,8FP0,8FOW,8CUR,7VDU,7UXK,7UXI,7SA0,7S9X,7S85,7S84,7S7A,7S4T,7RXO,7RWE,7RA5,7NVQ,7M2F,7KJS,7B5R,7B5L,6P3W,6ATH,5K4J,5JQ8,5JQ5,5IF1,5IEY,5IEX,5IEV,5FP6,5FP5,5D1J,5ANO,5ANK,5ANJ,5ANI,5ANG,5ANE,5AND,5A14,4RJ3,4NJ3,4LYN,4KD1,4II5,4FX3,4FKW,4FKV,4FKU,4FKT,4FKS,4FKR,4FKQ,4FKP,4FKO,4FKL,4FKJ,4FKI,4FKG,4EK8,4EK6,4EK5,4EK4,4EK3,4D1Z,4D1X,4BZD,4BGH,4BCP,4BCO,4BCN,4BCK,4ACM,3WBL,3UNK,3UNJ,3ULI,3TNW,3TIZ,3TIY,3TI1,3SW7,3SW4,3S2P,3PJ8,3NS9,3MY5,3LFS,3LFQ,3LFN,3LE6,3IGG,3IG7,3FZ1,3F5X,3EZV,3EZR,3EOC,3EJ1,3EID,3BHV,3BHU,3BHT,2XNB,2XMY,2X1N,2WHB,2WFY,2WEV,2W1H,2W17,2W06,2W05,2VV9,2VU3,2VTT,2VTS,2VTR,2VTQ,2VTP,2VTO,2VTN,2VTM,2VTL,2VTJ,2VTI,2VTH,2VTA,2V22,2V0D,2UZO,2UZN,2UZL,2UZE,2UZD,2UZB,2UUE,2R64,2R3R,2R3Q,2R3P,2R3O,2R3N,2R3M,2R3L,2R3K,2R3J,2R3I,2R3H,2R3G,2R3F,2J9M,2I40,2FVD,2EXM,2DUV,2CLX,2CJM,2C6T,2C6O,2C6M,2C6L,2C6K,2C6I,2C69,2C68,2C5Y,2C5X,2C5V,2C5O,2C5N,2BTS,2BTR,2BHH,2BHE,2B55,2B54,2B53,2B52,2A4L,2A0C,1YKR,1Y91,1Y8Y,1WCC,1W8C,1W0X,1VYZ,1V1K,1URW,1URC,1R78,1PYE,1PXP,1PXO,1PXN,1PXM,1PXL,1PXK,1PXJ,1PXI,1PW2,1PF8,1P2A,1OL2,1OL1,1OKW,1OKV,1OIR,1OIQ,1KE9,1KE8,1KE7,1KE6,1KE5,1JVP,1JSV,1JSU,1JST,1HCL,1HCK,1H0W,1H0V,1H08,1H07,1H01,1H00,1GZ8,1GIH,1G5S,1FVV,1FVT,1FQ1,1FIN,1F5Q,1E1X,1E1V,1DM2,1DI8,1CKP,1BUH,1B39,1B38,1AQ1,8ERN,8ERD,7RWF,6OQI,5UQ3,5UQ2,5UQ1,4BCQ,4BCM,9UGF,9UAW,9UAU,9JJ5,9GNO,8YQE,8YPW,7ZPC,7UG1,7MKX,6Q4K,6Q4J,6Q4H,6Q4F,6Q4E,6Q4D,6Q4C,6Q4B,6Q4A,6Q49,6Q48,6Q3F,6Q3C,6Q3B,6GUK,6GUH,5OSJ,5OO0,5NEV,5MHQ,5CYI,4GCJ,4EZ7,4EZ3,4ERW,4CFX,4CFW,4CFM,3SQQ,3S1H,3S0O,3S00,3RZB,3RPY,3RPV,3RPR,3RPO,3ROY,3RNI,3RMF,3RM7,3RM6,3RKB,3RK9,3RK7,3RK5,3RJC,3RAL,3RAK,3RAI,3RAH,3R9O,3R9N,3R9H,3R9D,3R8Z,3R8V,3R8U,3R8P,3R8M,3R8L,3R83,3R7Y,3R7V,3R7U,3R7I,3R7E,3R73,3R71,3R6X,3R28,3R1Y,3R1S,3R1Q,3QZI,3QZH,3QZG,3QZF,3QXP,3QXO,3QX4,3QX2,3QWK,3QWJ,3QU0,3QTZ,3QTX,3QTW,3QTU,3QTS,3QTR,3QTQ,3QRU,3QRT,3QQL,3QQK,3QQJ,3QQH,3QQG,3QQF,3QL8,3PY1,3PY0,3PXZ,3PXY,3PXR,3PXQ,3PXF,2WMB,2WMA,1H28,1H27,1H26,1H25,1H24,1H1S,1H1R	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941	A8K7C6 O75100							MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA	9NYQ,9OB6,9OB5,9OB4,9OB3,9OB2,9NYR,9GP3,9GOP,9D0X,9D0W,9D0V,8VQ4,8VQ3,1W98,9BJC,8H6T,8H6P	G1/S-specific cyclin-E1	CCNE1_HUMAN	P24864	A8K684 Q14091 Q8NFG1 Q92501 Q9UD21