BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 166112 O=C(NC1CCc2cc(-c3ccc(F)cc3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25FN2O2/c24-19-5-1-15(2-6-19)17-3-7-20-18(13-17)4-8-21(20)25-23(27)28-22-14-26-11-9-16(22)10-12-26/h1-3,5-7,13,16,21-22H,4,8-12,14H2,(H,25,27) XNJILEOCBHTMQH-UHFFFAOYSA-N 229951 (S)-quinuclidin-3-yl (5-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 1 Mannosyl-oligosaccharide glucosidase 9.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229951 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229951&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312617 336949431 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166113 O=C(NC1CCc2cc(-c3ccc(Cl)cc3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25ClN2O2/c24-19-5-1-15(2-6-19)17-3-7-20-18(13-17)4-8-21(20)25-23(27)28-22-14-26-11-9-16(22)10-12-26/h1-3,5-7,13,16,21-22H,4,8-12,14H2,(H,25,27) WZCDJYGJISONTJ-UHFFFAOYSA-N 229952 (S)-quinuclidin-3-yl (5-(4-chlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 2 Mannosyl-oligosaccharide glucosidase 17.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229952 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229952&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312815 336949432 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166114 O=C(NC1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O2/c25-24(26,27)19-5-1-15(2-6-19)17-3-7-20-18(13-17)4-8-21(20)28-23(30)31-22-14-29-11-9-16(22)10-12-29/h1-3,5-7,13,16,21-22H,4,8-12,14H2,(H,28,30) ZQJBMNZYAUADHD-UHFFFAOYSA-N 229953 (S)-quinuclidin-3-yl (5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 3 Mannosyl-oligosaccharide glucosidase 21.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229953 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229953&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 127053861 336949433 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166115 O=C(NC1CCc2cc(-c3ccc(OC(F)(F)F)cc3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O3/c25-24(26,27)32-19-5-1-15(2-6-19)17-3-7-20-18(13-17)4-8-21(20)28-23(30)31-22-14-29-11-9-16(22)10-12-29/h1-3,5-7,13,16,21-22H,4,8-12,14H2,(H,28,30) ZZSAWPCHUSOJMO-UHFFFAOYSA-N 229954 (S)-quinuclidin-3-yl (5-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 4 Mannosyl-oligosaccharide glucosidase 11.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229954 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229954&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312757 336949434 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166116 O=C(NC1CCc2cc(-c3cccc(F)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25FN2O2/c24-19-3-1-2-16(13-19)17-4-6-20-18(12-17)5-7-21(20)25-23(27)28-22-14-26-10-8-15(22)9-11-26/h1-4,6,12-13,15,21-22H,5,7-11,14H2,(H,25,27) NBHBCFQLPCWGQE-UHFFFAOYSA-N 229955 (S)-quinuclidin-3-yl (5-(3-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 5 Mannosyl-oligosaccharide glucosidase 3.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229955 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229955&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 127053862 336949435 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166117 O=C(NC1CCc2cc(-c3cccc(Cl)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25ClN2O2/c24-19-3-1-2-16(13-19)17-4-6-20-18(12-17)5-7-21(20)25-23(27)28-22-14-26-10-8-15(22)9-11-26/h1-4,6,12-13,15,21-22H,5,7-11,14H2,(H,25,27) IHUGGCAVVWLXDZ-UHFFFAOYSA-N 229956 (S)-quinuclidin-3-yl (5-(3-chlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 6 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229956 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229956&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312588 336949436 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166118 O=C(NC1CCc2cc(-c3cccc(C(F)(F)F)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O2/c25-24(26,27)19-3-1-2-16(13-19)17-4-6-20-18(12-17)5-7-21(20)28-23(30)31-22-14-29-10-8-15(22)9-11-29/h1-4,6,12-13,15,21-22H,5,7-11,14H2,(H,28,30) KVTNUCWYXCBDIL-UHFFFAOYSA-N 229957 (S)-quinuclidin-3-yl (5-(3-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 7 Mannosyl-oligosaccharide glucosidase 1.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229957 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229957&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312574 336949437 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166119 O=C(NC1CCc2cc(-c3cccc(OC(F)(F)F)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O3/c25-24(26,27)32-19-3-1-2-16(13-19)17-4-6-20-18(12-17)5-7-21(20)28-23(30)31-22-14-29-10-8-15(22)9-11-29/h1-4,6,12-13,15,21-22H,5,7-11,14H2,(H,28,30) QJGWSGRXJMWSGL-UHFFFAOYSA-N 229958 (S)-quinuclidin-3-yl (5-(3-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 8 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229958 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229958&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 67355124 336949438 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166120 O=C(NC1CCc2cc(-c3ccccc3F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25FN2O2/c24-20-4-2-1-3-18(20)16-5-7-19-17(13-16)6-8-21(19)25-23(27)28-22-14-26-11-9-15(22)10-12-26/h1-5,7,13,15,21-22H,6,8-12,14H2,(H,25,27) QUYZKOWFLFHEIM-UHFFFAOYSA-N 229959 (S)-quinuclidin-3-yl (5-(2-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 9 Mannosyl-oligosaccharide glucosidase 2.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229959 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229959&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 127053863 336949439 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166121 O=C(NC1CCc2cc(-c3ccccc3Cl)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25ClN2O2/c24-20-4-2-1-3-18(20)16-5-7-19-17(13-16)6-8-21(19)25-23(27)28-22-14-26-11-9-15(22)10-12-26/h1-5,7,13,15,21-22H,6,8-12,14H2,(H,25,27) XGBCXEMTEBMYPW-UHFFFAOYSA-N 229960 (S)-quinuclidin-3-yl (5-(2-chlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 10 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229960 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229960&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 127053864 336949440 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166122 O=C(NC1CCc2cc(-c3ccccc3C(F)(F)F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O2/c25-24(26,27)20-4-2-1-3-18(20)16-5-7-19-17(13-16)6-8-21(19)28-23(30)31-22-14-29-11-9-15(22)10-12-29/h1-5,7,13,15,21-22H,6,8-12,14H2,(H,28,30) QFRJKCWUUQAYQJ-UHFFFAOYSA-N 229961 (S)-quinuclidin-3-yl (5-(2-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 11 Mannosyl-oligosaccharide glucosidase 22.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229961 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229961&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 127053865 336949441 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166123 O=C(NC1CCc2cc(-c3ccccc3OC(F)(F)F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O3/c25-24(26,27)32-21-4-2-1-3-19(21)17-5-7-18-16(13-17)6-8-20(18)28-23(30)31-22-14-29-11-9-15(22)10-12-29/h1-5,7,13,15,20,22H,6,8-12,14H2,(H,28,30) BXGIHHHAVRUHQF-UHFFFAOYSA-N 229962 (S)-quinuclidin-3-yl (5-(2-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 12 Mannosyl-oligosaccharide glucosidase 14.8 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229962 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229962&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 127053866 336949442 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166124 Cc1ccc(-c2ccc3c(c2)CCC3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C24H28N2O2/c1-16-2-4-17(5-3-16)19-6-8-21-20(14-19)7-9-22(21)25-24(27)28-23-15-26-12-10-18(23)11-13-26/h2-6,8,14,18,22-23H,7,9-13,15H2,1H3,(H,25,27) RWCKZYRWJKTOPI-UHFFFAOYSA-N 229963 (S)-quinuclidin-3-yl (5-(p-tolyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 13 Mannosyl-oligosaccharide glucosidase 9.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229963 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229963&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 127053867 336949443 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166125 O=C(NC1CCc2cc(-c3ccc(OC(F)F)cc3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H26F2N2O3/c25-23(26)30-19-5-1-15(2-6-19)17-3-7-20-18(13-17)4-8-21(20)27-24(29)31-22-14-28-11-9-16(22)10-12-28/h1-3,5-7,13,16,21-23H,4,8-12,14H2,(H,27,29) IFQPLAUYRHIQPT-UHFFFAOYSA-N 229964 (S)-quinuclidin-3-yl (5-(4-(difluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 14 Mannosyl-oligosaccharide glucosidase 8.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229964 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229964&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312806 336949444 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166126 O=C(NC1CCc2cc(-c3ccc(F)c(F)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-19-5-2-16(12-20(19)25)15-1-4-18-17(11-15)3-6-21(18)26-23(28)29-22-13-27-9-7-14(22)8-10-27/h1-2,4-5,11-12,14,21-22H,3,6-10,13H2,(H,26,28) XNIKVEXLRJROKX-UHFFFAOYSA-N 229965 (S)-quinuclidin-3-yl (5-(3,4-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 15 Mannosyl-oligosaccharide glucosidase 11.8 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229965 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229965&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312713 336949445 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166127 O=C(NC1CCc2cc(-c3ccc(F)cc3F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-17-3-5-18(20(25)12-17)15-1-4-19-16(11-15)2-6-21(19)26-23(28)29-22-13-27-9-7-14(22)8-10-27/h1,3-5,11-12,14,21-22H,2,6-10,13H2,(H,26,28) WPPFRDTYBMJBQU-UHFFFAOYSA-N 229966 (S)-quinuclidin-3-yl (5-(2,4-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 16 Mannosyl-oligosaccharide glucosidase 12.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229966 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229966&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 67377037 336949446 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166128 O=C(NC1CCc2cc(-c3cccc(F)c3F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-19-3-1-2-18(22(19)25)16-4-6-17-15(12-16)5-7-20(17)26-23(28)29-21-13-27-10-8-14(21)9-11-27/h1-4,6,12,14,20-21H,5,7-11,13H2,(H,26,28) NTSVYNCVBOAGQF-UHFFFAOYSA-N 229967 (S)-quinuclidin-3-yl (5-(2,3-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 17 Mannosyl-oligosaccharide glucosidase 3.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229967 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229967&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312667 336949447 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166129 O=C(NC1CCc2cc(-c3cc(F)ccc3F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-17-3-5-20(25)19(12-17)16-1-4-18-15(11-16)2-6-21(18)26-23(28)29-22-13-27-9-7-14(22)8-10-27/h1,3-5,11-12,14,21-22H,2,6-10,13H2,(H,26,28) WNCRADVXCAJTIK-UHFFFAOYSA-N 229968 (S)-quinuclidin-3-yl (5-(2,5-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 18 Mannosyl-oligosaccharide glucosidase 5.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229968 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229968&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312620 336949448 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166130 O=C(NC1CCc2cc(-c3cc(F)cc(F)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-18-10-17(11-19(25)12-18)15-1-3-20-16(9-15)2-4-21(20)26-23(28)29-22-13-27-7-5-14(22)6-8-27/h1,3,9-12,14,21-22H,2,4-8,13H2,(H,26,28) KHKKCBWAUCOGDJ-UHFFFAOYSA-N 229969 (S)-quinuclidin-3-yl (5-(3,5-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 19 Mannosyl-oligosaccharide glucosidase 12.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229969 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229969&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312575 336949449 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166131 O=C(NC1CCc2cc(-c3ccc(F)c(F)c3F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H23F3N2O2/c24-18-5-4-17(21(25)22(18)26)15-1-3-16-14(11-15)2-6-19(16)27-23(29)30-20-12-28-9-7-13(20)8-10-28/h1,3-5,11,13,19-20H,2,6-10,12H2,(H,27,29) XEBCKFSZTMRYOO-UHFFFAOYSA-N 229970 (S)-quinuclidin-3-yl (5-(2,3,4-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 20 Mannosyl-oligosaccharide glucosidase 16.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229970 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229970&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312690 336949450 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166132 O=C(NC1CCc2cc(-c3cc(F)c(F)cc3F)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H23F3N2O2/c24-18-11-20(26)19(25)10-17(18)15-1-3-16-14(9-15)2-4-21(16)27-23(29)30-22-12-28-7-5-13(22)6-8-28/h1,3,9-11,13,21-22H,2,4-8,12H2,(H,27,29) IEMATVAWMKXGSV-UHFFFAOYSA-N 229971 (S)-quinuclidin-3-yl (5-(2,4,5-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 21 Mannosyl-oligosaccharide glucosidase 12.3 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229971 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229971&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312799 336949451 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166133 O=C(NC1CCc2cc(-c3cc(Cl)cc(Cl)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24Cl2N2O2/c24-18-10-17(11-19(25)12-18)15-1-3-20-16(9-15)2-4-21(20)26-23(28)29-22-13-27-7-5-14(22)6-8-27/h1,3,9-12,14,21-22H,2,4-8,13H2,(H,26,28) ZEXFBYJOMJGHIK-UHFFFAOYSA-N 229972 (S)-quinuclidin-3-yl (5-(3,5-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 22 Mannosyl-oligosaccharide glucosidase 15.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=229972 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=229972&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 121312749 336949452 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166134 O=C(NC1CCc2cc(-c3ccc(Cl)c(Cl)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24Cl2N2O2/c24-19-5-2-16(12-20(19)25)15-1-4-18-17(11-15)3-6-21(18)26-23(28)29-22-13-27-9-7-14(22)8-10-27/h1-2,4-5,11-12,14,21-22H,3,6-10,13H2,(H,26,28) GTKOHTDJOUAQPY-UHFFFAOYSA-N 237209 (S)-quinuclidin-3-yl (5-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 23 Mannosyl-oligosaccharide glucosidase 10.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237209 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237209&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012474 340130770 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166135 O=C(NC1CCc2cc(-c3cc(Cl)ccc3Cl)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24Cl2N2O2/c24-17-3-5-20(25)19(12-17)16-1-4-18-15(11-16)2-6-21(18)26-23(28)29-22-13-27-9-7-14(22)8-10-27/h1,3-5,11-12,14,21-22H,2,6-10,13H2,(H,26,28) JHNFCUYNXXCKCA-UHFFFAOYSA-N 237210 (S)-quinuclidin-3-yl (5-(2,5-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 24 Mannosyl-oligosaccharide glucosidase 1.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237210 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237210&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012475 340130771 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166136 O=C(NC1CCc2ccc(-c3ccc(F)cc3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25FN2O2/c24-19-6-3-15(4-7-19)18-2-1-16-5-8-21(20(16)13-18)25-23(27)28-22-14-26-11-9-17(22)10-12-26/h1-4,6-7,13,17,21-22H,5,8-12,14H2,(H,25,27) GVXPDNOQCPWHSU-UHFFFAOYSA-N 237211 (S)-quinuclidin-3-yl (6-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 25 Mannosyl-oligosaccharide glucosidase 65.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237211 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237211&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012476 340130772 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166137 O=C(NC1CCc2ccc(-c3ccc(Cl)cc3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25ClN2O2/c24-19-6-3-15(4-7-19)18-2-1-16-5-8-21(20(16)13-18)25-23(27)28-22-14-26-11-9-17(22)10-12-26/h1-4,6-7,13,17,21-22H,5,8-12,14H2,(H,25,27) LGISRDQIZWKRLG-UHFFFAOYSA-N 237212 (S)-quinuclidin-3-yl (6-(4-chlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 26 Mannosyl-oligosaccharide glucosidase 48.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237212 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237212&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012477 340130773 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166138 O=C(NC1CCc2ccc(-c3ccc(C(F)(F)F)cc3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O2/c25-24(26,27)19-6-3-15(4-7-19)18-2-1-16-5-8-21(20(16)13-18)28-23(30)31-22-14-29-11-9-17(22)10-12-29/h1-4,6-7,13,17,21-22H,5,8-12,14H2,(H,28,30) SORLQSVDSIKGMS-UHFFFAOYSA-N 237213 (S)-quinuclidin-3-yl (6-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 27 Mannosyl-oligosaccharide glucosidase 55.3 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237213 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237213&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012478 340130774 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166139 O=C(NC1CCc2ccc(-c3ccc(OC(F)(F)F)cc3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O3/c25-24(26,27)32-19-6-3-15(4-7-19)18-2-1-16-5-8-21(20(16)13-18)28-23(30)31-22-14-29-11-9-17(22)10-12-29/h1-4,6-7,13,17,21-22H,5,8-12,14H2,(H,28,30) ANGUPEGQHIQANN-UHFFFAOYSA-N 237214 (S)-quinuclidin-3-yl (6-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 28 Mannosyl-oligosaccharide glucosidase 79.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237214 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237214&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012479 340130775 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166140 O=C(NC1CCc2ccc(-c3cccc(F)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25FN2O2/c24-19-3-1-2-17(12-19)18-5-4-15-6-7-21(20(15)13-18)25-23(27)28-22-14-26-10-8-16(22)9-11-26/h1-5,12-13,16,21-22H,6-11,14H2,(H,25,27) XBMKWKNSZJNVNZ-UHFFFAOYSA-N 237215 (S)-quinuclidin-3-yl (6-(3-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 29 Mannosyl-oligosaccharide glucosidase 38.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237215 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237215&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012480 340130776 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166141 O=C(NC1CCc2ccc(-c3cccc(Cl)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25ClN2O2/c24-19-3-1-2-17(12-19)18-5-4-15-6-7-21(20(15)13-18)25-23(27)28-22-14-26-10-8-16(22)9-11-26/h1-5,12-13,16,21-22H,6-11,14H2,(H,25,27) FQWHCMTZXPXZLM-UHFFFAOYSA-N 237216 (S)-quinuclidin-3-yl (6-(3-chlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 30 Mannosyl-oligosaccharide glucosidase 34.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237216 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237216&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012481 340130777 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166142 O=C(NC1CCc2ccc(-c3cccc(C(F)(F)F)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O2/c25-24(26,27)19-3-1-2-17(12-19)18-5-4-15-6-7-21(20(15)13-18)28-23(30)31-22-14-29-10-8-16(22)9-11-29/h1-5,12-13,16,21-22H,6-11,14H2,(H,28,30) PEUZDEXZLOEKSI-UHFFFAOYSA-N 237217 (S)-quinuclidin-3-yl (6-(3-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 31 Mannosyl-oligosaccharide glucosidase 41.5 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237217 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237217&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012482 340130778 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166143 O=C(NC1CCc2ccc(-c3cccc(OC(F)(F)F)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O3/c25-24(26,27)32-19-3-1-2-17(12-19)18-5-4-15-6-7-21(20(15)13-18)28-23(30)31-22-14-29-10-8-16(22)9-11-29/h1-5,12-13,16,21-22H,6-11,14H2,(H,28,30) FDDZXYNKGQCBCS-UHFFFAOYSA-N 237218 (S)-quinuclidin-3-yl (6-(3-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 32 Mannosyl-oligosaccharide glucosidase 71.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237218 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237218&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012483 340130779 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166144 O=C(NC1CCc2ccc(-c3ccccc3F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25FN2O2/c24-20-4-2-1-3-18(20)17-6-5-15-7-8-21(19(15)13-17)25-23(27)28-22-14-26-11-9-16(22)10-12-26/h1-6,13,16,21-22H,7-12,14H2,(H,25,27) XMWRGHRMIIYJMS-UHFFFAOYSA-N 237219 (S)-quinuclidin-3-yl (6-(2-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 33 Mannosyl-oligosaccharide glucosidase 25.8 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237219 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237219&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012484 340130780 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166145 O=C(NC1CCc2ccc(-c3ccccc3Cl)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H25ClN2O2/c24-20-4-2-1-3-18(20)17-6-5-15-7-8-21(19(15)13-17)25-23(27)28-22-14-26-11-9-16(22)10-12-26/h1-6,13,16,21-22H,7-12,14H2,(H,25,27) ITTIUSULTDXXIE-UHFFFAOYSA-N 237220 (S)-quinuclidin-3-yl (6-(2-chlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 34 Mannosyl-oligosaccharide glucosidase 13.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237220 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237220&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012485 340130781 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166146 O=C(NC1CCc2ccc(-c3ccccc3C(F)(F)F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O2/c25-24(26,27)20-4-2-1-3-18(20)17-6-5-15-7-8-21(19(15)13-17)28-23(30)31-22-14-29-11-9-16(22)10-12-29/h1-6,13,16,21-22H,7-12,14H2,(H,28,30) WSAZIYJNNIQAQT-UHFFFAOYSA-N 237221 (S)-quinuclidin-3-yl (6-(2-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 35 Mannosyl-oligosaccharide glucosidase 20.3 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237221 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237221&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012486 340130782 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166147 O=C(NC1CCc2ccc(-c3ccccc3OC(F)(F)F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H25F3N2O3/c25-24(26,27)32-21-4-2-1-3-18(21)17-6-5-15-7-8-20(19(15)13-17)28-23(30)31-22-14-29-11-9-16(22)10-12-29/h1-6,13,16,20,22H,7-12,14H2,(H,28,30) GCGXQOSJVILXKJ-UHFFFAOYSA-N 237222 (S)-quinuclidin-3-yl (6-(2-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 36 Mannosyl-oligosaccharide glucosidase 14.3 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237222 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237222&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012487 340130783 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166148 O=C(NC1CCc2ccc(-c3ccc(OC(F)F)cc3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C24H26F2N2O3/c25-23(26)30-19-6-3-15(4-7-19)18-2-1-16-5-8-21(20(16)13-18)27-24(29)31-22-14-28-11-9-17(22)10-12-28/h1-4,6-7,13,17,21-23H,5,8-12,14H2,(H,27,29) MNWRDSUYYBXYCW-UHFFFAOYSA-N 237223 (S)-quinuclidin-3-yl (6-(4-(difluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 37 Mannosyl-oligosaccharide glucosidase 33.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237223 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237223&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012488 340130784 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166149 Cc1ccc(-c2ccc3c(c2)C(NC(=O)O[C@H]2CN4CCC2CC4)CC3)cc1 InChI=1S/C24H28N2O2/c1-16-2-4-17(5-3-16)20-7-6-18-8-9-22(21(18)14-20)25-24(27)28-23-15-26-12-10-19(23)11-13-26/h2-7,14,19,22-23H,8-13,15H2,1H3,(H,25,27) FUNZQWUICPIQJI-UHFFFAOYSA-N 237224 (S)-quinuclidin-3-yl (6-(p-tolyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 38 Mannosyl-oligosaccharide glucosidase 33.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237224 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237224&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012489 340130785 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166150 O=C(NC1CCc2ccc(-c3ccc(F)c(F)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-19-5-3-17(12-20(19)25)16-2-1-14-4-6-21(18(14)11-16)26-23(28)29-22-13-27-9-7-15(22)8-10-27/h1-3,5,11-12,15,21-22H,4,6-10,13H2,(H,26,28) INULTRQSTKNPHC-UHFFFAOYSA-N 237225 (S)-quinuclidin-3-yl (6-(3,4-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 39 Mannosyl-oligosaccharide glucosidase 26.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237225 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237225&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 71490863 340130786 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166151 O=C(NC1CCc2ccc(-c3cc(F)cc(F)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-18-9-17(10-19(25)12-18)16-2-1-14-3-4-21(20(14)11-16)26-23(28)29-22-13-27-7-5-15(22)6-8-27/h1-2,9-12,15,21-22H,3-8,13H2,(H,26,28) LIICOXBGTHYLNC-UHFFFAOYSA-N 237226 (S)-quinuclidin-3-yl (6-(3,5-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 40 Mannosyl-oligosaccharide glucosidase 40.4 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237226 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237226&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012490 340130787 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166152 O=C(NC1CCc2ccc(-c3cc(F)ccc3F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-17-4-5-20(25)18(12-17)16-2-1-14-3-6-21(19(14)11-16)26-23(28)29-22-13-27-9-7-15(22)8-10-27/h1-2,4-5,11-12,15,21-22H,3,6-10,13H2,(H,26,28) RIEMVMVXSYHHFJ-UHFFFAOYSA-N 237227 (S)-quinuclidin-3-yl (6-(2,5-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 41 Mannosyl-oligosaccharide glucosidase 16.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237227 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237227&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012491 340130788 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166153 O=C(NC1CCc2ccc(-c3cccc(F)c3F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-19-3-1-2-17(22(19)25)16-5-4-14-6-7-20(18(14)12-16)26-23(28)29-21-13-27-10-8-15(21)9-11-27/h1-5,12,15,20-21H,6-11,13H2,(H,26,28) ZVFNMDNMFJOQFW-UHFFFAOYSA-N 237228 (S)-quinuclidin-3-yl (6-(2,3-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 42 Mannosyl-oligosaccharide glucosidase 23.6 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237228 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237228&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012492 340130789 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166154 O=C(NC1CCc2ccc(-c3ccc(F)cc3F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24F2N2O2/c24-17-4-5-18(20(25)12-17)16-2-1-14-3-6-21(19(14)11-16)26-23(28)29-22-13-27-9-7-15(22)8-10-27/h1-2,4-5,11-12,15,21-22H,3,6-10,13H2,(H,26,28) OOXUXGKMADQGAC-UHFFFAOYSA-N 237229 (S)-quinuclidin-3-yl (6-(2,4-difluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 43 Mannosyl-oligosaccharide glucosidase 33.4 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237229 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237229&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012493 340130790 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166155 O=C(NC1CCc2ccc(-c3cc(F)c(F)cc3F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H23F3N2O2/c24-18-11-20(26)19(25)10-16(18)15-2-1-13-3-4-21(17(13)9-15)27-23(29)30-22-12-28-7-5-14(22)6-8-28/h1-2,9-11,14,21-22H,3-8,12H2,(H,27,29) DKWLRYBQROJRPB-UHFFFAOYSA-N 237230 (S)-quinuclidin-3-yl (6-(2,4,5-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 44 Mannosyl-oligosaccharide glucosidase 18.6 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237230 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237230&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012494 340130791 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166156 O=C(NC1CCc2ccc(-c3ccc(F)c(F)c3F)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H23F3N2O2/c24-18-5-4-16(21(25)22(18)26)15-2-1-13-3-6-19(17(13)11-15)27-23(29)30-20-12-28-9-7-14(20)8-10-28/h1-2,4-5,11,14,19-20H,3,6-10,12H2,(H,27,29) ILDOELOFXZHPCT-UHFFFAOYSA-N 239045 (S)-quinuclidin-3-yl (6-(2,3,4-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 45 Mannosyl-oligosaccharide glucosidase 33.3 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239045 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239045&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 59504108 340132333 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166157 O=C(NC1CCc2ccc(-c3cc(Cl)ccc3Cl)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24Cl2N2O2/c24-17-4-5-20(25)18(12-17)16-2-1-14-3-6-21(19(14)11-16)26-23(28)29-22-13-27-9-7-15(22)8-10-27/h1-2,4-5,11-12,15,21-22H,3,6-10,13H2,(H,26,28) MXFPNEVVUJWWEV-UHFFFAOYSA-N 239046 (S)-quinuclidin-3-yl (6-(2,5-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 46 Mannosyl-oligosaccharide glucosidase 8.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239046 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239046&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 71229841 340132334 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166158 O=C(NC1CCc2ccc(-c3ccc(Cl)c(Cl)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24Cl2N2O2/c24-19-5-3-17(12-20(19)25)16-2-1-14-4-6-21(18(14)11-16)26-23(28)29-22-13-27-9-7-15(22)8-10-27/h1-3,5,11-12,15,21-22H,4,6-10,13H2,(H,26,28) BNGYXGXQWIXOLI-UHFFFAOYSA-N 239047 (S)-quinuclidin-3-yl (6-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 47 Mannosyl-oligosaccharide glucosidase 37.5 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239047 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239047&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012630 340132335 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166159 O=C(NC1CCc2ccc(-c3cc(Cl)cc(Cl)c3)cc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H24Cl2N2O2/c24-18-9-17(10-19(25)12-18)16-2-1-14-3-4-21(20(14)11-16)26-23(28)29-22-13-27-7-5-15(22)6-8-27/h1-2,9-12,15,21-22H,3-8,13H2,(H,26,28) LSVMGFDROBZPPO-UHFFFAOYSA-N 239048 (S)-quinuclidin-3-yl (6-(3,5-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 48 Mannosyl-oligosaccharide glucosidase 58.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239048 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239048&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012631 340132336 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166160 CC1(C)Cc2ccc(-c3ccc(F)cc3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29FN2O2/c1-25(2)14-19-4-3-18(16-5-7-20(26)8-6-16)13-21(19)23(25)27-24(29)30-22-15-28-11-9-17(22)10-12-28/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,27,29) WRPLEFZCIKQLBH-UHFFFAOYSA-N 239049 (S)-quinuclidin-3-yl (6-(4-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 49 Mannosyl-oligosaccharide glucosidase 9.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239049 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239049&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 59504000 340132337 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166161 CC1(C)Cc2ccc(-c3ccc(Cl)cc3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29ClN2O2/c1-25(2)14-19-4-3-18(16-5-7-20(26)8-6-16)13-21(19)23(25)27-24(29)30-22-15-28-11-9-17(22)10-12-28/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,27,29) XNVQNHMJOVLQGQ-UHFFFAOYSA-N 239050 (S)-quinuclidin-3-yl (6-(4-chlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 50 Mannosyl-oligosaccharide glucosidase 9.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239050 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239050&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 71229414 340132338 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166162 CC1(C)Cc2ccc(-c3ccc(C(F)(F)F)cc3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O2/c1-25(2)14-19-4-3-18(16-5-7-20(8-6-16)26(27,28)29)13-21(19)23(25)30-24(32)33-22-15-31-11-9-17(22)10-12-31/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,30,32) BUVZZKUTXTUOBX-UHFFFAOYSA-N 239051 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 51 Mannosyl-oligosaccharide glucosidase 7.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239051 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239051&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 71230183 340132339 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166163 CC1(C)Cc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O3/c1-25(2)14-19-4-3-18(16-5-7-20(8-6-16)34-26(27,28)29)13-21(19)23(25)30-24(32)33-22-15-31-11-9-17(22)10-12-31/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,30,32) POKZRMBYZQRZTB-UHFFFAOYSA-N 239052 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 52 Mannosyl-oligosaccharide glucosidase 14.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239052 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239052&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 71230185 340132340 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166164 CC1(C)Cc2ccc(-c3cccc(F)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29FN2O2/c1-25(2)14-19-7-6-18(17-4-3-5-20(26)12-17)13-21(19)23(25)27-24(29)30-22-15-28-10-8-16(22)9-11-28/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,27,29) PMDIOFPGIUGUSD-UHFFFAOYSA-N 239053 (S)-quinuclidin-3-yl (6-(3-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 53 Mannosyl-oligosaccharide glucosidase 8.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239053 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239053&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012632 340132341 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166165 CC1(C)Cc2ccc(-c3cccc(Cl)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29ClN2O2/c1-25(2)14-19-7-6-18(17-4-3-5-20(26)12-17)13-21(19)23(25)27-24(29)30-22-15-28-10-8-16(22)9-11-28/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,27,29) MAOXKZORWBTMQA-UHFFFAOYSA-N 239054 (S)-quinuclidin-3-yl (6-(3-chlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 54 Mannosyl-oligosaccharide glucosidase 20.6 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239054 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239054&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012633 340132342 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166166 CC1(C)Cc2ccc(-c3cccc(C(F)(F)F)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O2/c1-25(2)14-19-7-6-18(17-4-3-5-20(12-17)26(27,28)29)13-21(19)23(25)30-24(32)33-22-15-31-10-8-16(22)9-11-31/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,30,32) KMPXUSFHQMKEPM-UHFFFAOYSA-N 239055 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(3-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 55 Mannosyl-oligosaccharide glucosidase 32.4 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239055 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239055&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012634 340132343 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166167 CC1(C)Cc2ccc(-c3cccc(OC(F)(F)F)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O3/c1-25(2)14-19-7-6-18(17-4-3-5-20(12-17)34-26(27,28)29)13-21(19)23(25)30-24(32)33-22-15-31-10-8-16(22)9-11-31/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,30,32) NKQFIMIXISRDKU-UHFFFAOYSA-N 239056 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(3-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 56 Mannosyl-oligosaccharide glucosidase 32.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239056 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239056&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 71230312 340132344 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166168 CC1(C)Cc2ccc(-c3ccccc3F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29FN2O2/c1-25(2)14-18-8-7-17(19-5-3-4-6-21(19)26)13-20(18)23(25)27-24(29)30-22-15-28-11-9-16(22)10-12-28/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,27,29) QTOHGCBVPLETIQ-UHFFFAOYSA-N 239057 (S)-quinuclidin-3-yl (6-(2-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 57 Mannosyl-oligosaccharide glucosidase 2.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239057 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239057&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 129012635 340132345 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166169 CC1(C)Cc2ccc(-c3ccccc3Cl)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29ClN2O2/c1-25(2)14-18-8-7-17(19-5-3-4-6-21(19)26)13-20(18)23(25)27-24(29)30-22-15-28-11-9-16(22)10-12-28/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,27,29) SEJUSBUYFQGKHQ-UHFFFAOYSA-N 240744 (S)-quinuclidin-3-yl (6-(2-chlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 58 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=240744 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=240744&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 56649302 375078191 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166170 CC1(C)Cc2ccc(-c3ccccc3C(F)(F)F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O2/c1-25(2)14-18-8-7-17(19-5-3-4-6-21(19)26(27,28)29)13-20(18)23(25)30-24(32)33-22-15-31-11-9-16(22)10-12-31/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,30,32) GRTXBXFCFXQOGM-UHFFFAOYSA-N 240745 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(2-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 59 Mannosyl-oligosaccharide glucosidase 5.44 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=240745 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=240745&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 56839343 341093117 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166171 Cc1ccc(-c2ccc3c(c2)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C26H32N2O2/c1-17-4-6-18(7-5-17)20-8-9-21-15-26(2,3)24(22(21)14-20)27-25(29)30-23-16-28-12-10-19(23)11-13-28/h4-9,14,19,23-24H,10-13,15-16H2,1-3H3,(H,27,29) SRRZLPTUFDMRRU-UHFFFAOYSA-N 240746 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(p-tolyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 60 Mannosyl-oligosaccharide glucosidase 16.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=240746 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=240746&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 56839344 375078192 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166172 CC1(C)Cc2ccc(-c3ccc(OC(F)F)cc3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H30F2N2O3/c1-26(2)14-19-4-3-18(16-5-7-20(8-6-16)32-24(27)28)13-21(19)23(26)29-25(31)33-22-15-30-11-9-17(22)10-12-30/h3-8,13,17,22-24H,9-12,14-15H2,1-2H3,(H,29,31) USQOBEXPOIBNLY-UHFFFAOYSA-N 240747 (S)-quinuclidin-3-yl (6-(4-(difluoromethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 61 Mannosyl-oligosaccharide glucosidase 12.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=240747 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=240747&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 56839536 375078193 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166173 CC1(C)Cc2ccc(-c3ccc(F)c(F)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-18-4-3-16(17-5-6-20(26)21(27)12-17)11-19(18)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) GGSQXDXIADFQLQ-UHFFFAOYSA-N 261909 (S)-quinuclidin-3-yl (6-(3,4-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 62 Mannosyl-oligosaccharide glucosidase 13.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=261909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=261909&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 118159248 376223747 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166174 CC1(C)Cc2ccc(-c3ccc(F)cc3F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-4-3-16(19-6-5-18(26)12-21(19)27)11-20(17)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) NUXHBONGNHRYNP-UHFFFAOYSA-N 261935 (S)-quinuclidin-3-yl (6-(2,4-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 63 Mannosyl-oligosaccharide glucosidase 7.55 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=261935 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=261935&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 118857196 376223773 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166175 CC1(C)Cc2ccc(-c3cccc(F)c3F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-7-6-16(18-4-3-5-20(26)22(18)27)12-19(17)23(25)28-24(30)31-21-14-29-10-8-15(21)9-11-29/h3-7,12,15,21,23H,8-11,13-14H2,1-2H3,(H,28,30) ZSBDNWFKJYNDDK-UHFFFAOYSA-N 261953 (S)-quinuclidin-3-yl (6-(2,3-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 64 Mannosyl-oligosaccharide glucosidase 3.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=261953 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=261953&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 118159318 376223791 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166176 CC1(C)Cc2ccc(-c3cc(F)ccc3F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-4-3-16(19-12-18(26)5-6-21(19)27)11-20(17)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) ISMPVRHJBHPWHV-UHFFFAOYSA-N 261971 (S)-quinuclidin-3-yl (6-(2,5-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 65 Mannosyl-oligosaccharide glucosidase 5.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=261971 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=261971&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 118159332 376223809 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166177 CC1(C)Cc2ccc(-c3cc(F)cc(F)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-4-3-16(18-9-19(26)12-20(27)10-18)11-21(17)23(25)28-24(30)31-22-14-29-7-5-15(22)6-8-29/h3-4,9-12,15,22-23H,5-8,13-14H2,1-2H3,(H,28,30) IXMQUCAHALISIF-UHFFFAOYSA-N 276094 (S)-quinuclidin-3-yl (6-(3,5-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 66 Mannosyl-oligosaccharide glucosidase 30.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276094 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276094&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302255 378157766 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166178 CC1(C)Cc2ccc(-c3ccc(F)c(F)c3F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27F3N2O2/c1-25(2)12-16-4-3-15(17-5-6-19(26)22(28)21(17)27)11-18(16)23(25)29-24(31)32-20-13-30-9-7-14(20)8-10-30/h3-6,11,14,20,23H,7-10,12-13H2,1-2H3,(H,29,31) JQMLYSGWGUNRNU-UHFFFAOYSA-N 276096 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(2,3,4-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 67 Mannosyl-oligosaccharide glucosidase 12.3 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276096 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276096&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309369 378157768 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166179 CC1(C)Cc2ccccc2C1(NC(=O)O[C@H]1CN2CCC1CC2)c1cc(F)c(F)cc1F InChI=1S/C25H27F3N2O2/c1-24(2)13-16-5-3-4-6-17(16)25(24,18-11-20(27)21(28)12-19(18)26)29-23(31)32-22-14-30-9-7-15(22)8-10-30/h3-6,11-12,15,22H,7-10,13-14H2,1-2H3,(H,29,31) OWIQOIKBBZQCAG-UHFFFAOYSA-N 276097 (S)-quinuclidin-3-yl (2,2-dimethyl-(2,4,5-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 68 Mannosyl-oligosaccharide glucosidase 15.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276097 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276097&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309370 378157769 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166180 CC1(C)Cc2ccc(-c3cc(Cl)cc(Cl)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28Cl2N2O2/c1-25(2)13-17-4-3-16(18-9-19(26)12-20(27)10-18)11-21(17)23(25)28-24(30)31-22-14-29-7-5-15(22)6-8-29/h3-4,9-12,15,22-23H,5-8,13-14H2,1-2H3,(H,28,30) CWHUSWHEFWEMRC-UHFFFAOYSA-N 276098 (S)-quinuclidin-3-yl (6-(3,5-dichlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 69 Mannosyl-oligosaccharide glucosidase 109 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276098 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276098&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309372 378157770 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166181 CC1(C)Cc2ccc(-c3ccc(Cl)c(Cl)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28Cl2N2O2/c1-25(2)13-18-4-3-16(17-5-6-20(26)21(27)12-17)11-19(18)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) IQXMEKJPVDUVLI-UHFFFAOYSA-N 276099 (S)-quinuclidin-3-yl (6-(3,4-dichlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 70 Mannosyl-oligosaccharide glucosidase 20.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276099 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276099&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302187 378157771 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166182 CC1(C)Cc2ccc(-c3cc(Cl)ccc3Cl)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28Cl2N2O2/c1-25(2)13-17-4-3-16(19-12-18(26)5-6-21(19)27)11-20(17)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) LTLZCRDIOCVNDM-UHFFFAOYSA-N 276100 (S)-quinuclidin-3-yl (6-(2,5-dichlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 71 Mannosyl-oligosaccharide glucosidase 13.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276100 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276100&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309371 378157772 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166183 COCCOc1ccc(-c2ccc3c(c2)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C28H36N2O4/c1-28(2)17-22-5-4-21(19-6-8-23(9-7-19)33-15-14-32-3)16-24(22)26(28)29-27(31)34-25-18-30-12-10-20(25)11-13-30/h4-9,16,20,25-26H,10-15,17-18H2,1-3H3,(H,29,31) JWECFHKINGNBHI-UHFFFAOYSA-N 276101 (S)-quinuclidin-3-yl (6-(4-(2-methoxyethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 72 Mannosyl-oligosaccharide glucosidase 10.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276101 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276101&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309373 378157773 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166184 CC1(C)Cc2cc(-c3ccc(F)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29FN2O2/c1-25(2)14-19-13-18(16-3-6-20(26)7-4-16)5-8-21(19)23(25)27-24(29)30-22-15-28-11-9-17(22)10-12-28/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,27,29) ASXVHYTYDCRETL-UHFFFAOYSA-N 276102 (S)-quinuclidin-3-yl (5-(4-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 73 Mannosyl-oligosaccharide glucosidase 22.5 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276102 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276102&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309374 378157774 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166185 CC1(C)Cc2cc(-c3ccc(Cl)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29ClN2O2/c1-25(2)14-19-13-18(16-3-6-20(26)7-4-16)5-8-21(19)23(25)27-24(29)30-22-15-28-11-9-17(22)10-12-28/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,27,29) JNNAMZCZYPDFFA-UHFFFAOYSA-N 276104 (S)-quinuclidin-3-yl (5-(4-chlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 74 Mannosyl-oligosaccharide glucosidase 24.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276104 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276104&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309376 378157776 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166186 CC1(C)Cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O2/c1-25(2)14-19-13-18(16-3-6-20(7-4-16)26(27,28)29)5-8-21(19)23(25)30-24(32)33-22-15-31-11-9-17(22)10-12-31/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,30,32) OTLJKXDSVITAOB-UHFFFAOYSA-N 276105 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 75 Mannosyl-oligosaccharide glucosidase 14.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276105 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276105&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309377 378157777 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166187 CC1(C)Cc2cc(-c3ccc(OC(F)(F)F)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O3/c1-25(2)14-19-13-18(16-3-6-20(7-4-16)34-26(27,28)29)5-8-21(19)23(25)30-24(32)33-22-15-31-11-9-17(22)10-12-31/h3-8,13,17,22-23H,9-12,14-15H2,1-2H3,(H,30,32) HFGLDKFKULGSNO-UHFFFAOYSA-N 276108 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 76 Mannosyl-oligosaccharide glucosidase 5.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276108 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276108&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311673 378157780 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166188 CC1(C)Cc2cc(-c3cccc(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29FN2O2/c1-25(2)14-19-12-18(17-4-3-5-20(26)13-17)6-7-21(19)23(25)27-24(29)30-22-15-28-10-8-16(22)9-11-28/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,27,29) NMKXSJJYAXGSBE-UHFFFAOYSA-N 276109 (S)-quinuclidin-3-yl (5-(3-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 77 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276109 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276109&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309379 378157781 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166189 CC1(C)Cc2cc(-c3cccc(Cl)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29ClN2O2/c1-25(2)14-19-12-18(17-4-3-5-20(26)13-17)6-7-21(19)23(25)27-24(29)30-22-15-28-10-8-16(22)9-11-28/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,27,29) ZIQVWFUHPYCLCH-UHFFFAOYSA-N 276110 (S)-quinuclidin-3-yl (5-(3-chlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 78 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276110 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276110&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309385 378157782 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166190 CC1(C)Cc2cc(-c3cccc(C(F)(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O2/c1-25(2)14-19-12-18(17-4-3-5-20(13-17)26(27,28)29)6-7-21(19)23(25)30-24(32)33-22-15-31-10-8-16(22)9-11-31/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,30,32) BHPJMKNEKQCCCX-UHFFFAOYSA-N 276111 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(3-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 79 Mannosyl-oligosaccharide glucosidase 2.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276111 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276111&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309381 378157783 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166191 CC1(C)Cc2ccc(-c3cccc(OC(F)(F)F)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O3/c1-25(2)14-19-7-6-18(17-4-3-5-20(12-17)34-26(27,28)29)13-21(19)23(25)30-24(32)33-22-15-31-10-8-16(22)9-11-31/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,30,32) NKQFIMIXISRDKU-UHFFFAOYSA-N 276112 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(3-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 80 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276112 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276112&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309387 378157784 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166192 CC1(C)Cc2cc(-c3ccccc3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29FN2O2/c1-25(2)14-18-13-17(19-5-3-4-6-21(19)26)7-8-20(18)23(25)27-24(29)30-22-15-28-11-9-16(22)10-12-28/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,27,29) BRQSVQRCPFRFGD-UHFFFAOYSA-N 276113 (S)-quinuclidin-3-yl (5-(2-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 81 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276113 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276113&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311742 378157785 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166193 CC1(C)Cc2cc(-c3ccccc3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H29ClN2O2/c1-25(2)14-18-13-17(19-5-3-4-6-21(19)26)7-8-20(18)23(25)27-24(29)30-22-15-28-11-9-16(22)10-12-28/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,27,29) QBKHZQJHBMWUHK-UHFFFAOYSA-N 276114 (S)-quinuclidin-3-yl (5-(2-chlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 82 Mannosyl-oligosaccharide glucosidase 2.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276114 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276114&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309384 378157786 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166194 CC1(C)Cc2cc(-c3ccccc3C(F)(F)F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O2/c1-25(2)14-18-13-17(19-5-3-4-6-21(19)26(27,28)29)7-8-20(18)23(25)30-24(32)33-22-15-31-11-9-16(22)10-12-31/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,30,32) HOCAROKVCWSTBL-UHFFFAOYSA-N 276117 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(2-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 83 Mannosyl-oligosaccharide glucosidase 7.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276117 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276117&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309389 378157789 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166195 CC1(C)Cc2cc(-c3ccccc3OC(F)(F)F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H29F3N2O3/c1-25(2)14-18-13-17(19-5-3-4-6-21(19)34-26(27,28)29)7-8-20(18)23(25)30-24(32)33-22-15-31-11-9-16(22)10-12-31/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,30,32) QKZYKFOEIZPNLK-UHFFFAOYSA-N 276118 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(2-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 84 Mannosyl-oligosaccharide glucosidase 7.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276118 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276118&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302373 378157790 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166196 Cc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C26H32N2O2/c1-17-4-6-18(7-5-17)20-8-9-22-21(14-20)15-26(2,3)24(22)27-25(29)30-23-16-28-12-10-19(23)11-13-28/h4-9,14,19,23-24H,10-13,15-16H2,1-3H3,(H,27,29) XIKOBONJVGLSAX-UHFFFAOYSA-N 276119 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(p-tolyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 85 Mannosyl-oligosaccharide glucosidase 3.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276119 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276119&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309390 378157791 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166197 CC1(C)Cc2cc(-c3ccc(OC(F)F)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H30F2N2O3/c1-26(2)14-19-13-18(16-3-6-20(7-4-16)32-24(27)28)5-8-21(19)23(26)29-25(31)33-22-15-30-11-9-17(22)10-12-30/h3-8,13,17,22-24H,9-12,14-15H2,1-2H3,(H,29,31) CXYSLRCWKNPWFZ-UHFFFAOYSA-N 276120 (S)-quinuclidin-3-yl (5-(4-(difluoromethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 86 Mannosyl-oligosaccharide glucosidase 3.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276120 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276120&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309401 378157792 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166198 CC1(C)Cc2cc(-c3ccc(F)c(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-18-11-16(17-4-6-20(26)21(27)12-17)3-5-19(18)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) VMOFDHWKCJDHIL-UHFFFAOYSA-N 276121 (S)-quinuclidin-3-yl (5-(3,4-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 87 Mannosyl-oligosaccharide glucosidase 9.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276121 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276121&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309391 378157793 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166199 CC1(C)Cc2cc(-c3cc(F)ccc3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-11-16(20-12-18(26)4-6-21(20)27)3-5-19(17)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) FCHSCMHTAPYCAP-UHFFFAOYSA-N 276122 (S)-quinuclidin-3-yl (5-(2,5-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 88 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276122 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276122&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309393 378157794 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166200 CC1(C)Cc2cc(-c3ccc(F)cc3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-11-16(19-6-4-18(26)12-21(19)27)3-5-20(17)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) NPRMAGCBSSEFMW-UHFFFAOYSA-N 276123 (S)-quinuclidin-3-yl (5-(2,4-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 89 Mannosyl-oligosaccharide glucosidase 8.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276123 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276123&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309392 378157795 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166201 CC1(C)Cc2cc(-c3cc(F)cc(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-18-9-16(17-10-19(26)12-20(27)11-17)3-4-21(18)23(25)28-24(30)31-22-14-29-7-5-15(22)6-8-29/h3-4,9-12,15,22-23H,5-8,13-14H2,1-2H3,(H,28,30) TXNVVOXXXTWECL-UHFFFAOYSA-N 276124 (S)-quinuclidin-3-yl (5-(3,5-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 90 Mannosyl-oligosaccharide glucosidase 11.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276124 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276124&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309402 378157796 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166202 CC1(C)Cc2cc(-c3cccc(F)c3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-12-16(18-4-3-5-20(26)22(18)27)6-7-19(17)23(25)28-24(30)31-21-14-29-10-8-15(21)9-11-29/h3-7,12,15,21,23H,8-11,13-14H2,1-2H3,(H,28,30) CFNOAKIKDBFPKN-UHFFFAOYSA-N 276125 (S)-quinuclidin-3-yl (5-(2,3-difluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 91 Mannosyl-oligosaccharide glucosidase 2.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276125 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276125&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309394 378157797 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166203 CC1(C)Cc2cc(-c3ccc(Cl)c(Cl)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28Cl2N2O2/c1-25(2)13-18-11-16(17-4-6-20(26)21(27)12-17)3-5-19(18)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) SHDPGQPLRUNQTE-UHFFFAOYSA-N 276126 (S)-quinuclidin-3-yl (5-(3,4-dichlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 92 Mannosyl-oligosaccharide glucosidase 16.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276126 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276126&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309398 378157798 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166204 CC1(C)Cc2cc(-c3cc(Cl)ccc3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28Cl2N2O2/c1-25(2)13-17-11-16(20-12-18(26)4-6-21(20)27)3-5-19(17)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) OCSJEIJSKPXGPU-UHFFFAOYSA-N 276127 (S)-quinuclidin-3-yl (5-(2,5-dichlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 93 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276127 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276127&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309405 378157799 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166205 CC1(C)Cc2cc(-c3cc(Cl)cc(Cl)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28Cl2N2O2/c1-25(2)13-18-9-16(17-10-19(26)12-20(27)11-17)3-4-21(18)23(25)28-24(30)31-22-14-29-7-5-15(22)6-8-29/h3-4,9-12,15,22-23H,5-8,13-14H2,1-2H3,(H,28,30) JCQSBAPHHRBKRI-UHFFFAOYSA-N 276128 (S)-quinuclidin-3-yl (5-(3,5-dichlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 94 Mannosyl-oligosaccharide glucosidase 9.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276128 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276128&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309396 378157800 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166206 CC1(C)Cc2cc(-c3ccc(F)c(F)c3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27F3N2O2/c1-25(2)12-16-11-15(17-5-6-19(26)22(28)21(17)27)3-4-18(16)23(25)29-24(31)32-20-13-30-9-7-14(20)8-10-30/h3-6,11,14,20,23H,7-10,12-13H2,1-2H3,(H,29,31) HUVAZUQCESPEBS-UHFFFAOYSA-N 276129 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(2,3,4-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 95 Mannosyl-oligosaccharide glucosidase 11.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276129 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276129&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309397 378157801 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166207 CC1(C)Cc2cc(-c3cc(F)c(F)cc3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27F3N2O2/c1-25(2)12-16-9-15(18-10-20(27)21(28)11-19(18)26)3-4-17(16)23(25)29-24(31)32-22-13-30-7-5-14(22)6-8-30/h3-4,9-11,14,22-23H,5-8,12-13H2,1-2H3,(H,29,31) BKSKHTRUDOCEDB-UHFFFAOYSA-N 276130 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(2,4,5-trifluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 96 Mannosyl-oligosaccharide glucosidase 6.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276130 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276130&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309399 378157802 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166208 COCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C28H36N2O4/c1-28(2)17-22-16-21(19-4-7-23(8-5-19)33-15-14-32-3)6-9-24(22)26(28)29-27(31)34-25-18-30-12-10-20(25)11-13-30/h4-9,16,20,25-26H,10-15,17-18H2,1-3H3,(H,29,31) MJKQUNSKZOLRDK-UHFFFAOYSA-N 276131 (S)-quinuclidin-3-yl (5-(4-(2-methoxyethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 97 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276131 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276131&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309403 378157803 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166209 COCCOc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C28H36N2O4/c1-28(2)17-22-15-21(20-5-4-6-23(16-20)33-14-13-32-3)7-8-24(22)26(28)29-27(31)34-25-18-30-11-9-19(25)10-12-30/h4-8,15-16,19,25-26H,9-14,17-18H2,1-3H3,(H,29,31) BZRPXGQKOUKOPN-UHFFFAOYSA-N 276132 (S)-quinuclidin-3-yl (5-(3-(2-methoxyethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 98 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276132 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276132&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309400 378157804 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166210 COCCOc1ccccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H36N2O4/c1-28(2)17-21-16-20(22-6-4-5-7-24(22)33-15-14-32-3)8-9-23(21)26(28)29-27(31)34-25-18-30-12-10-19(25)11-13-30/h4-9,16,19,25-26H,10-15,17-18H2,1-3H3,(H,29,31) FFHBOKSIVPLXEU-UHFFFAOYSA-N 276133 (S)-quinuclidin-3-yl (5-(2-(2-methoxyethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 99 Mannosyl-oligosaccharide glucosidase 6.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276133 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276133&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309404 378157805 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166211 COCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C27H34N2O4/c1-27(2)15-21-14-20(18-4-7-22(8-5-18)32-17-31-3)6-9-23(21)25(27)28-26(30)33-24-16-29-12-10-19(24)11-13-29/h4-9,14,19,24-25H,10-13,15-17H2,1-3H3,(H,28,30) KRJNYTRUDNGEIR-UHFFFAOYSA-N 276134 (S)-quinuclidin-3-yl (5-(4-(methoxymethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 100 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276134 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276134&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302341 378157806 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166212 COCOc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O4/c1-27(2)15-21-13-20(19-5-4-6-22(14-19)32-17-31-3)7-8-23(21)25(27)28-26(30)33-24-16-29-11-9-18(24)10-12-29/h4-8,13-14,18,24-25H,9-12,15-17H2,1-3H3,(H,28,30) AQTPGINSGRZZTP-UHFFFAOYSA-N 276135 (S)-quinuclidin-3-yl (5-(3-(methoxymethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 101 Mannosyl-oligosaccharide glucosidase 1.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276135 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276135&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302440 378157807 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166213 COCOc1ccccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H34N2O4/c1-27(2)15-20-14-19(21-6-4-5-7-23(21)32-17-31-3)8-9-22(20)25(27)28-26(30)33-24-16-29-12-10-18(24)11-13-29/h4-9,14,18,24-25H,10-13,15-17H2,1-3H3,(H,28,30) APZNQEUCRBLFFB-UHFFFAOYSA-N 276136 (S)-quinuclidin-3-yl (5-(2-(methoxymethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 102 Mannosyl-oligosaccharide glucosidase 4.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276136 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276136&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309410 378157808 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166214 COc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H32N2O3/c1-26(2)15-20-13-19(18-5-4-6-21(14-18)30-3)7-8-22(20)24(26)27-25(29)31-23-16-28-11-9-17(23)10-12-28/h4-8,13-14,17,23-24H,9-12,15-16H2,1-3H3,(H,27,29) UUQDAJAFOPEVCG-UHFFFAOYSA-N 276137 (S)-quinuclidin-3-yl (5-(3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 103 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276137 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276137&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309414 378157809 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166215 CCOc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O3/c1-4-31-22-7-5-6-19(15-22)20-8-9-23-21(14-20)16-27(2,3)25(23)28-26(30)32-24-17-29-12-10-18(24)11-13-29/h5-9,14-15,18,24-25H,4,10-13,16-17H2,1-3H3,(H,28,30) SBRLYXXCSXMXTR-UHFFFAOYSA-N 276138 (S)-quinuclidin-3-yl (5-(3-ethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 104 Mannosyl-oligosaccharide glucosidase 1.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276138 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276138&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309406 378157810 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166216 CC(C)Oc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C28H36N2O3/c1-18(2)32-23-7-5-6-20(15-23)21-8-9-24-22(14-21)16-28(3,4)26(24)29-27(31)33-25-17-30-12-10-19(25)11-13-30/h5-9,14-15,18-19,25-26H,10-13,16-17H2,1-4H3,(H,29,31) SMVOOOYTGKOGSN-UHFFFAOYSA-N 276139 (S)-quinuclidin-3-yl (5-(3-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 105 Mannosyl-oligosaccharide glucosidase 1.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276139 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276139&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309407 378157811 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166217 CN(C)c1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H35N3O2/c1-27(2)16-21-14-20(19-6-5-7-22(15-19)29(3)4)8-9-23(21)25(27)28-26(31)32-24-17-30-12-10-18(24)11-13-30/h5-9,14-15,18,24-25H,10-13,16-17H2,1-4H3,(H,28,31) QYQSTDVTXNMURW-UHFFFAOYSA-N 276140 (S)-quinuclidin-3-yl (5-(3-(dimethylamino)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 106 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276140 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276140&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309411 378157812 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166218 CSc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H32N2O2S/c1-26(2)15-20-13-19(18-5-4-6-21(14-18)31-3)7-8-22(20)24(26)27-25(29)30-23-16-28-11-9-17(23)10-12-28/h4-8,13-14,17,23-24H,9-12,15-16H2,1-3H3,(H,27,29) VBJHYKJZIRXMEH-UHFFFAOYSA-N 276141 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(3-(methylthio)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 107 Mannosyl-oligosaccharide glucosidase 1.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276141 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276141&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309412 378157813 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166219 CCc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O2/c1-4-18-6-5-7-20(14-18)21-8-9-23-22(15-21)16-27(2,3)25(23)28-26(30)31-24-17-29-12-10-19(24)11-13-29/h5-9,14-15,19,24-25H,4,10-13,16-17H2,1-3H3,(H,28,30) SNGYNCKAVCHOIX-UHFFFAOYSA-N 276142 (S)-quinuclidin-3-yl (5-(3-ethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 108 Mannosyl-oligosaccharide glucosidase 2.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276142 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276142&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309408 378157814 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166220 CC(C)c1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C28H36N2O2/c1-18(2)20-6-5-7-21(14-20)22-8-9-24-23(15-22)16-28(3,4)26(24)29-27(31)32-25-17-30-12-10-19(25)11-13-30/h5-9,14-15,18-19,25-26H,10-13,16-17H2,1-4H3,(H,29,31) CNWOPLHIQGSZSB-UHFFFAOYSA-N 276143 (S)-quinuclidin-3-yl (5-(3-isopropylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 109 Mannosyl-oligosaccharide glucosidase 3.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276143 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276143&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309416 378157815 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166221 CC(C)(C)c1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C29H38N2O2/c1-28(2,3)23-8-6-7-20(16-23)21-9-10-24-22(15-21)17-29(4,5)26(24)30-27(32)33-25-18-31-13-11-19(25)12-14-31/h6-10,15-16,19,25-26H,11-14,17-18H2,1-5H3,(H,30,32) SSIRTUNFYXYLDB-UHFFFAOYSA-N 276144 (S)-quinuclidin-3-yl (5-(3-(tert-butyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 110 Mannosyl-oligosaccharide glucosidase 6.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276144 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276144&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302350 378157816 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166222 CC1(C)Cc2cc(-c3ccc4c(c3)OC(F)(F)O4)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28F2N2O4/c1-25(2)13-18-11-16(17-4-6-20-21(12-17)34-26(27,28)33-20)3-5-19(18)23(25)29-24(31)32-22-14-30-9-7-15(22)8-10-30/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,29,31) QKRCXOFEWMSIGH-UHFFFAOYSA-N 276145 (S)-quinuclidin-3-yl (5-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 111 Mannosyl-oligosaccharide glucosidase 3.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276145 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276145&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309409 378157817 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166223 CC1(C)Cc2cc(-c3ccc4c(c3)OCCO4)ccc2C1NC(=O)O[C@@H]1CN2CCC1CC2 InChI=1S/C27H32N2O4/c1-27(2)15-20-13-18(19-4-6-22-23(14-19)32-12-11-31-22)3-5-21(20)25(27)28-26(30)33-24-16-29-9-7-17(24)8-10-29/h3-6,13-14,17,24-25H,7-12,15-16H2,1-2H3,(H,28,30) AXYXOKRJPXMHNK-UHFFFAOYSA-N 276146 (S)-quinuclidin-3-yl (5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 112 Mannosyl-oligosaccharide glucosidase 2.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276146 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276146&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309415 378157818 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166224 CC1(C)Cc2cc(-c3ccc4c(c3)CCO4)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H32N2O3/c1-27(2)15-21-14-18(19-4-6-23-20(13-19)9-12-31-23)3-5-22(21)25(27)28-26(30)32-24-16-29-10-7-17(24)8-11-29/h3-6,13-14,17,24-25H,7-12,15-16H2,1-2H3,(H,28,30) LTOWKOMTHGHDBJ-UHFFFAOYSA-N 276148 (S)-quinuclidin-3-yl (5-(2,3-dihydrobenzofuran-5-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 113 Mannosyl-oligosaccharide glucosidase 6.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276148 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276148&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302325 378157820 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166225 CC1(C)Cc2cc(-c3cccc(OCCN4CCOCC4)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C31H41N3O4/c1-31(2)20-25-18-24(23-4-3-5-26(19-23)37-17-14-33-12-15-36-16-13-33)6-7-27(25)29(31)32-30(35)38-28-21-34-10-8-22(28)9-11-34/h3-7,18-19,22,28-29H,8-17,20-21H2,1-2H3,(H,32,35) AXRSMWIGJRLKNA-UHFFFAOYSA-N 276149 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(3-(2-morpholinoethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 114 Mannosyl-oligosaccharide glucosidase 3.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276149 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276149&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309417 378157821 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166226 CC1(C)Cc2cc(-c3ccc(OCCF)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H33FN2O3/c1-27(2)16-21-15-20(18-3-6-22(7-4-18)32-14-11-28)5-8-23(21)25(27)29-26(31)33-24-17-30-12-9-19(24)10-13-30/h3-8,15,19,24-25H,9-14,16-17H2,1-2H3,(H,29,31) RERDNTHXWLASFA-UHFFFAOYSA-N 276150 (S)-quinuclidin-3-yl (5-(4-(2-fluoroethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 115 Mannosyl-oligosaccharide glucosidase 3.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276150 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276150&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302222 378157822 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166227 CC1(C)Cc2cc(-c3ccc(OCC(F)(F)F)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H31F3N2O3/c1-26(2)14-20-13-19(17-3-6-21(7-4-17)34-16-27(28,29)30)5-8-22(20)24(26)31-25(33)35-23-15-32-11-9-18(23)10-12-32/h3-8,13,18,23-24H,9-12,14-16H2,1-2H3,(H,31,33) OOTWCLBNGQTKOI-UHFFFAOYSA-N 276151 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-(2,2,2-trifluoroethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 116 Mannosyl-oligosaccharide glucosidase 1.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276151 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276151&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302382 378157823 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166228 CC1(C)Cc2cc(-c3ccc(OCCN4CCOCC4)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C31H41N3O4/c1-31(2)20-25-19-24(22-3-6-26(7-4-22)37-18-15-33-13-16-36-17-14-33)5-8-27(25)29(31)32-30(35)38-28-21-34-11-9-23(28)10-12-34/h3-8,19,23,28-29H,9-18,20-21H2,1-2H3,(H,32,35) VJBBBVPRBJUVOZ-UHFFFAOYSA-N 276152 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-(2-morpholinoethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 117 Mannosyl-oligosaccharide glucosidase 3.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276152 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276152&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309418 378157824 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166229 CC1(C)Cc2cc(-c3ccnc(C(F)(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F3N3O2/c1-24(2)13-18-11-16(17-5-8-29-21(12-17)25(26,27)28)3-4-19(18)22(24)30-23(32)33-20-14-31-9-6-15(20)7-10-31/h3-5,8,11-12,15,20,22H,6-7,9-10,13-14H2,1-2H3,(H,30,32) KLTNEMZIZMZMMY-UHFFFAOYSA-N 276153 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(2-(trifluoromethyl)pyridin-4-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 118 Mannosyl-oligosaccharide glucosidase 14.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276153 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276153&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309419 378157825 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166230 CC1(C)Cc2cc(-c3cc(Cl)ncc3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C24H27Cl2N3O2/c1-24(2)11-16-9-15(18-10-21(26)27-12-19(18)25)3-4-17(16)22(24)28-23(30)31-20-13-29-7-5-14(20)6-8-29/h3-4,9-10,12,14,20,22H,5-8,11,13H2,1-2H3,(H,28,30) JNDXPKBDYIEBTO-UHFFFAOYSA-N 276154 (S)-quinuclidin-3-yl (5-(2,5-dichloropyridin-4-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 119 Mannosyl-oligosaccharide glucosidase 10.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276154 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276154&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309421 378157826 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166231 CN1CCOc2cc(-c3ccc4c(c3)CC(C)(C)C4NC(=O)O[C@H]3CN4CCC3CC4)ccc21 InChI=1S/C28H35N3O3/c1-28(2)16-21-14-19(20-5-7-23-24(15-20)33-13-12-30(23)3)4-6-22(21)26(28)29-27(32)34-25-17-31-10-8-18(25)9-11-31/h4-7,14-15,18,25-26H,8-13,16-17H2,1-3H3,(H,29,32) PLMBQIHWQGQYJO-UHFFFAOYSA-N 276155 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 120 Mannosyl-oligosaccharide glucosidase 4.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276155 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276155&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309422 378157827 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166232 COc1ccc(Cl)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H31ClN2O3/c1-26(2)14-18-12-17(21-13-19(31-3)5-7-22(21)27)4-6-20(18)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) ATCRQFMBJVSCBA-UHFFFAOYSA-N 276158 (S)-quinuclidin-3-yl (5-(2-chloro-5-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 121 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276158 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276158&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309424 378157830 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166233 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1Cl InChI=1S/C26H31ClN2O3/c1-26(2)14-19-12-17(18-5-7-22(31-3)21(27)13-18)4-6-20(19)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) FNQYXOJODJBUDU-UHFFFAOYSA-N 276159 (S)-quinuclidin-3-yl (5-(3-chloro-4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 122 Mannosyl-oligosaccharide glucosidase 6.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276159 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276159&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309425 378157831 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166234 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(Cl)c1 InChI=1S/C26H31ClN2O3/c1-26(2)14-18-12-17(20-7-5-19(31-3)13-22(20)27)4-6-21(18)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) HICWIKOBCXWNJI-UHFFFAOYSA-N 276160 (S)-quinuclidin-3-yl (5-(2-chloro-4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 123 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276160 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276160&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309426 378157832 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166235 COc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1Cl InChI=1S/C26H31ClN2O3/c1-26(2)14-18-13-17(19-5-4-6-21(31-3)23(19)27)7-8-20(18)24(26)28-25(30)32-22-15-29-11-9-16(22)10-12-29/h4-8,13,16,22,24H,9-12,14-15H2,1-3H3,(H,28,30) UVNSSDBUXXTEGZ-UHFFFAOYSA-N 276161 (S)-quinuclidin-3-yl (5-(2-chloro-3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 124 Mannosyl-oligosaccharide glucosidase 3.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276161 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276161&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309427 378157833 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166236 COc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccc1Cl InChI=1S/C26H31ClN2O3/c1-26(2)14-19-12-17(18-5-7-21(27)22(13-18)31-3)4-6-20(19)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) DSJNKBQTBTUJSO-UHFFFAOYSA-N 276162 (S)-quinuclidin-3-yl (5-(4-chloro-3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 125 Mannosyl-oligosaccharide glucosidase 17.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276162 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276162&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302414 378157834 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166237 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(Cl)c1Cl InChI=1S/C26H30Cl2N2O3/c1-26(2)13-17-12-16(18-6-7-20(32-3)23(28)22(18)27)4-5-19(17)24(26)29-25(31)33-21-14-30-10-8-15(21)9-11-30/h4-7,12,15,21,24H,8-11,13-14H2,1-3H3,(H,29,31) GHLNROAGMFBRPO-UHFFFAOYSA-N 276163 (S)-quinuclidin-3-yl (5-(2,3-dichloro-4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 126 Mannosyl-oligosaccharide glucosidase 14.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276163 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276163&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309428 378157835 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166238 CC(C)Oc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1Cl InChI=1S/C28H35ClN2O3/c1-17(2)33-24-8-6-20(14-23(24)29)19-5-7-22-21(13-19)15-28(3,4)26(22)30-27(32)34-25-16-31-11-9-18(25)10-12-31/h5-8,13-14,17-18,25-26H,9-12,15-16H2,1-4H3,(H,30,32) NEOCZESTJWROQI-UHFFFAOYSA-N 276164 (S)-quinuclidin-3-yl (5-(3-chloro-4-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 127 Mannosyl-oligosaccharide glucosidase 5.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276164 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276164&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309429 378157836 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166239 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(F)c1 InChI=1S/C26H31FN2O3/c1-26(2)14-18-12-17(20-7-5-19(31-3)13-22(20)27)4-6-21(18)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) MCADAJVQUFULHD-UHFFFAOYSA-N 276165 (S)-quinuclidin-3-yl (5-(2-fluoro-4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 128 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276165 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276165&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311759 378157837 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166240 CN(C)c1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccc1F InChI=1S/C27H34FN3O2/c1-27(2)15-20-13-18(19-6-8-22(28)23(14-19)30(3)4)5-7-21(20)25(27)29-26(32)33-24-16-31-11-9-17(24)10-12-31/h5-8,13-14,17,24-25H,9-12,15-16H2,1-4H3,(H,29,32) HEPHXSUIONKUEY-UHFFFAOYSA-N 276166 (S)-quinuclidin-3-yl (5-(3-(dimethylamino)-4-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 129 Mannosyl-oligosaccharide glucosidase 5.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276166&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311752 378157838 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166241 CC1(C)Cc2cc(-c3ccc4c(c3)CCCO4)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H34N2O3/c1-28(2)16-22-15-19(20-6-8-24-21(14-20)4-3-13-32-24)5-7-23(22)26(28)29-27(31)33-25-17-30-11-9-18(25)10-12-30/h5-8,14-15,18,25-26H,3-4,9-13,16-17H2,1-2H3,(H,29,31) VYARJWJBCVJEJT-UHFFFAOYSA-N 276167 (S)-quinuclidin-3-yl (5-(chroman-6-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 130 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276167&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311800 378157839 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166242 CC1(C)Cc2cc(-c3ccc(C4CC4)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H34N2O2/c1-28(2)16-23-15-22(20-7-5-19(6-8-20)18-3-4-18)9-10-24(23)26(28)29-27(31)32-25-17-30-13-11-21(25)12-14-30/h5-10,15,18,21,25-26H,3-4,11-14,16-17H2,1-2H3,(H,29,31) YBDOUWANXDISRZ-UHFFFAOYSA-N 276168 (S)-quinuclidin-3-yl (5-(4-cyclopropylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 131 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276168 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276168&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311754 378157840 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166243 CN(C)c1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C27H35N3O2/c1-27(2)16-21-15-20(18-5-8-22(9-6-18)29(3)4)7-10-23(21)25(27)28-26(31)32-24-17-30-13-11-19(24)12-14-30/h5-10,15,19,24-25H,11-14,16-17H2,1-4H3,(H,28,31) GPDWOWVOPQIVGR-UHFFFAOYSA-N 276169 (S)-quinuclidin-3-yl (5-(4-(dimethylamino)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 132 Mannosyl-oligosaccharide glucosidase 3.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276169 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276169&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311753 378157841 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166244 CCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1F InChI=1S/C27H33FN2O3/c1-4-32-23-8-6-19(14-22(23)28)18-5-7-21-20(13-18)15-27(2,3)25(21)29-26(31)33-24-16-30-11-9-17(24)10-12-30/h5-8,13-14,17,24-25H,4,9-12,15-16H2,1-3H3,(H,29,31) XQEBBAWGOVERCS-UHFFFAOYSA-N 276170 (S)-quinuclidin-3-yl (5-(4-ethoxy-3-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 133 Mannosyl-oligosaccharide glucosidase 4.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276170 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276170&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309435 378157842 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166245 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C(F)(F)F InChI=1S/C27H31F3N2O3/c1-26(2)14-19-12-17(18-5-7-22(34-3)21(13-18)27(28,29)30)4-6-20(19)24(26)31-25(33)35-23-15-32-10-8-16(23)9-11-32/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,31,33) HSBDKYMIJCBAEV-UHFFFAOYSA-N 276171 (S)-quinuclidin-3-yl (5-(4-methoxy-3-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 134 Mannosyl-oligosaccharide glucosidase 6.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276171 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276171&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309438 378157843 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166246 CCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C28H36N2O3/c1-4-15-32-23-8-5-19(6-9-23)21-7-10-24-22(16-21)17-28(2,3)26(24)29-27(31)33-25-18-30-13-11-20(25)12-14-30/h5-10,16,20,25-26H,4,11-15,17-18H2,1-3H3,(H,29,31) BLHOOEWEUSEQSL-UHFFFAOYSA-N 276172 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-propoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 135 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276172 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276172&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309436 378157844 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166247 CC(C)COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H38N2O3/c1-19(2)18-33-24-8-5-20(6-9-24)22-7-10-25-23(15-22)16-29(3,4)27(25)30-28(32)34-26-17-31-13-11-21(26)12-14-31/h5-10,15,19,21,26-27H,11-14,16-18H2,1-4H3,(H,30,32) VUMVXWNKUAQFMP-UHFFFAOYSA-N 276173 (S)-quinuclidin-3-yl (5-(4-isobutoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 136 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276173&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309437 378157845 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166248 CC1(C)Cc2cc(-c3ccsc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C23H28N2O2S/c1-23(2)12-18-11-16(17-7-10-28-14-17)3-4-19(18)21(23)24-22(26)27-20-13-25-8-5-15(20)6-9-25/h3-4,7,10-11,14-15,20-21H,5-6,8-9,12-13H2,1-2H3,(H,24,26) JERBVOXAKREEIA-UHFFFAOYSA-N 276174 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(thiophen-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 137 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276174 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276174&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311714 378157846 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166249 Cc1cscc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C24H30N2O2S/c1-15-13-29-14-20(15)17-4-5-19-18(10-17)11-24(2,3)22(19)25-23(27)28-21-12-26-8-6-16(21)7-9-26/h4-5,10,13-14,16,21-22H,6-9,11-12H2,1-3H3,(H,25,27) YXYKMONCOMUWOH-UHFFFAOYSA-N 276175 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-methylthiophen-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 138 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276175 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276175&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309439 378157847 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166250 CN(C)CCOc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C29H39N3O3/c1-29(2)18-23-16-22(21-6-5-7-24(17-21)34-15-14-31(3)4)8-9-25(23)27(29)30-28(33)35-26-19-32-12-10-20(26)11-13-32/h5-9,16-17,20,26-27H,10-15,18-19H2,1-4H3,(H,30,33) KXMDFMGSOMIETL-UHFFFAOYSA-N 276176 (S)-quinuclidin-3-yl (5-(3-(2-(dimethylamino)ethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 139 Mannosyl-oligosaccharide glucosidase 10.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276176&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311801 378157848 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166251 CC1(C)Cc2cc(-c3cccc4ccncc34)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H31N3O2/c1-28(2)15-21-14-20(22-5-3-4-18-8-11-29-16-24(18)22)6-7-23(21)26(28)30-27(32)33-25-17-31-12-9-19(25)10-13-31/h3-8,11,14,16,19,25-26H,9-10,12-13,15,17H2,1-2H3,(H,30,32) MFUJQRSVPHALLE-UHFFFAOYSA-N 276177 (S)-quinuclidin-3-yl (5-(isoquinolin-8-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 140 Mannosyl-oligosaccharide glucosidase 1.000 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276177&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311713 378157849 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166252 CC1(C)Cc2cc(-c3cccc4cnccc34)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H31N3O2/c1-28(2)15-21-14-19(22-5-3-4-20-16-29-11-8-23(20)22)6-7-24(21)26(28)30-27(32)33-25-17-31-12-9-18(25)10-13-31/h3-8,11,14,16,18,25-26H,9-10,12-13,15,17H2,1-2H3,(H,30,32) YTNWMGIATYIXBB-UHFFFAOYSA-N 276178 (S)-quinuclidin-3-yl (5-(isoquinolin-5-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 141 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276178 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276178&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309442 378157850 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166253 CC1(C)Cc2cc(-c3cncc4ccccc34)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H31N3O2/c1-28(2)14-21-13-19(24-16-29-15-20-5-3-4-6-22(20)24)7-8-23(21)26(28)30-27(32)33-25-17-31-11-9-18(25)10-12-31/h3-8,13,15-16,18,25-26H,9-12,14,17H2,1-2H3,(H,30,32) WWUOALATOUDLHO-UHFFFAOYSA-N 276179 (S)-quinuclidin-3-yl (5-(isoquinolin-4-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 142 Mannosyl-oligosaccharide glucosidase 1.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276179 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276179&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309444 378157851 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166254 CC1(C)Cc2cc(-c3cnc4ccccc4c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H31N3O2/c1-28(2)15-21-13-19(22-14-20-5-3-4-6-24(20)29-16-22)7-8-23(21)26(28)30-27(32)33-25-17-31-11-9-18(25)10-12-31/h3-8,13-14,16,18,25-26H,9-12,15,17H2,1-2H3,(H,30,32) DVLKBVWZCYTQKY-UHFFFAOYSA-N 276180 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(quinolin-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 143 Mannosyl-oligosaccharide glucosidase 4.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276180 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276180&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311760 378157852 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166255 CC(C)Oc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C28H36N2O3/c1-18(2)32-23-8-5-19(6-9-23)21-7-10-24-22(15-21)16-28(3,4)26(24)29-27(31)33-25-17-30-13-11-20(25)12-14-30/h5-10,15,18,20,25-26H,11-14,16-17H2,1-4H3,(H,29,31) WHEBNHRXEYUDHD-UHFFFAOYSA-N 276181 (S)-quinuclidin-3-yl (5-(4-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 144 Mannosyl-oligosaccharide glucosidase 1.000 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276181 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276181&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311761 378157853 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166256 CC(C)Oc1ccccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H36N2O3/c1-18(2)32-24-8-6-5-7-22(24)20-9-10-23-21(15-20)16-28(3,4)26(23)29-27(31)33-25-17-30-13-11-19(25)12-14-30/h5-10,15,18-19,25-26H,11-14,16-17H2,1-4H3,(H,29,31) XFAIVPGOTQWBDZ-UHFFFAOYSA-N 276183 (S)-quinuclidin-3-yl (5-(2-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 145 Mannosyl-oligosaccharide glucosidase 4.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276183 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276183&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309447 378157855 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166257 CC(C)(C)c1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H38N2O2/c1-28(2,3)23-9-6-19(7-10-23)21-8-11-24-22(16-21)17-29(4,5)26(24)30-27(32)33-25-18-31-14-12-20(25)13-15-31/h6-11,16,20,25-26H,12-15,17-18H2,1-5H3,(H,30,32) SLPPLHIZTZIXRA-UHFFFAOYSA-N 276184 (S)-quinuclidin-3-yl (5-(4-(tert-butyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 146 Mannosyl-oligosaccharide glucosidase 3.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276184 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276184&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309448 378157856 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166258 CCc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C27H34N2O2/c1-4-18-5-7-19(8-6-18)21-9-10-23-22(15-21)16-27(2,3)25(23)28-26(30)31-24-17-29-13-11-20(24)12-14-29/h5-10,15,20,24-25H,4,11-14,16-17H2,1-3H3,(H,28,30) UQLSSNAATVYKGP-UHFFFAOYSA-N 276185 (S)-quinuclidin-3-yl (5-(4-ethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 147 Mannosyl-oligosaccharide glucosidase 1.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276185 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276185&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309449 378157857 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166259 CC1(C)Cc2cc(-c3ccc(N4CCOCC4)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H37N3O3/c1-29(2)18-23-17-22(20-3-6-24(7-4-20)32-13-15-34-16-14-32)5-8-25(23)27(29)30-28(33)35-26-19-31-11-9-21(26)10-12-31/h3-8,17,21,26-27H,9-16,18-19H2,1-2H3,(H,30,33) UYHHAZYGYHGHDP-UHFFFAOYSA-N 276186 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-morpholinophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 148 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276186 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276186&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309451 378157858 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166260 COCc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C27H34N2O3/c1-27(2)15-22-14-21(19-6-4-18(5-7-19)17-31-3)8-9-23(22)25(27)28-26(30)32-24-16-29-12-10-20(24)11-13-29/h4-9,14,20,24-25H,10-13,15-17H2,1-3H3,(H,28,30) UUJABKPULYOXEG-UHFFFAOYSA-N 276187 (S)-quinuclidin-3-yl (5-(4-(methoxymethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 149 Mannosyl-oligosaccharide glucosidase 1.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276187 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276187&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309452 378157859 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166261 CC1(C)Cc2cc(-c3ccc(OCC(F)F)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H32F2N2O3/c1-27(2)14-20-13-19(17-3-6-21(7-4-17)33-16-24(28)29)5-8-22(20)25(27)30-26(32)34-23-15-31-11-9-18(23)10-12-31/h3-8,13,18,23-25H,9-12,14-16H2,1-2H3,(H,30,32) GRPXZDWQHCUHRE-UHFFFAOYSA-N 276188 (S)-quinuclidin-3-yl (5-(4-(2,2-difluoroethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 150 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276188 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276188&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309453 378157860 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166262 Cc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccc1N1CCOCC1 InChI=1S/C30H39N3O3/c1-20-16-22(5-7-26(20)33-12-14-35-15-13-33)23-4-6-25-24(17-23)18-30(2,3)28(25)31-29(34)36-27-19-32-10-8-21(27)9-11-32/h4-7,16-17,21,27-28H,8-15,18-19H2,1-3H3,(H,31,34) NBSBWLWJQFLBPR-UHFFFAOYSA-N 276189 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(3-methyl-4-morpholinophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 151 Mannosyl-oligosaccharide glucosidase 2.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276189 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276189&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309454 378157861 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166263 CC1(C)Cc2cc(-c3ccc(N4CCOCC4)c(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H36FN3O3/c1-29(2)17-22-15-20(21-4-6-25(24(30)16-21)33-11-13-35-14-12-33)3-5-23(22)27(29)31-28(34)36-26-18-32-9-7-19(26)8-10-32/h3-6,15-16,19,26-27H,7-14,17-18H2,1-2H3,(H,31,34) UMZJVYBZLUIIBS-UHFFFAOYSA-N 276192 (S)-quinuclidin-3-yl (5-(3-fluoro-4-morpholinophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 152 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276192 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276192&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309455 378157864 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166264 CC1(C)Cc2cc(-c3ccc(N4CCOCC4)c(Cl)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H36ClN3O3/c1-29(2)17-22-15-20(21-4-6-25(24(30)16-21)33-11-13-35-14-12-33)3-5-23(22)27(29)31-28(34)36-26-18-32-9-7-19(26)8-10-32/h3-6,15-16,19,26-27H,7-14,17-18H2,1-2H3,(H,31,34) INNPJPBJHFQCDU-UHFFFAOYSA-N 276193 (S)-quinuclidin-3-yl (5-(3-chloro-4-morpholinophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 153 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276193 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276193&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309457 378157865 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166265 CC1(C)Cc2cc(-c3ccc4c(c3)OCCCO4)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H34N2O4/c1-28(2)16-21-14-19(20-5-7-23-24(15-20)33-13-3-12-32-23)4-6-22(21)26(28)29-27(31)34-25-17-30-10-8-18(25)9-11-30/h4-7,14-15,18,25-26H,3,8-13,16-17H2,1-2H3,(H,29,31) GJFDJWALXCQRID-UHFFFAOYSA-N 276194 (S)-quinuclidin-3-yl (5-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 154 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276194 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276194&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309458 378157866 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166266 CC1(C)Cc2cc(-c3cccc(C(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H30F2N2O2/c1-26(2)14-20-13-18(17-4-3-5-19(12-17)24(27)28)6-7-21(20)23(26)29-25(31)32-22-15-30-10-8-16(22)9-11-30/h3-7,12-13,16,22-24H,8-11,14-15H2,1-2H3,(H,29,31) PJAFASDUMWLDFL-UHFFFAOYSA-N 276195 (S)-quinuclidin-3-yl (5-(3-(difluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 155 Mannosyl-oligosaccharide glucosidase 1.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276195 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276195&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309462 378157867 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166267 CC1(C)Cc2cc(-c3cccc4cccnc34)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H31N3O2/c1-28(2)16-21-15-20(22-7-3-5-19-6-4-12-29-25(19)22)8-9-23(21)26(28)30-27(32)33-24-17-31-13-10-18(24)11-14-31/h3-9,12,15,18,24,26H,10-11,13-14,16-17H2,1-2H3,(H,30,32) IQQWCYHICZQDRG-UHFFFAOYSA-N 276196 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(quinolin-8-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 156 Mannosyl-oligosaccharide glucosidase 2.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276196 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276196&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309460 378157868 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166268 CC1(C)Cc2cc(-c3coc4ccccc34)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H30N2O3/c1-27(2)14-19-13-18(22-16-31-23-6-4-3-5-21(22)23)7-8-20(19)25(27)28-26(30)32-24-15-29-11-9-17(24)10-12-29/h3-8,13,16-17,24-25H,9-12,14-15H2,1-2H3,(H,28,30) BRHNZCHDQMRRDU-UHFFFAOYSA-N 276197 (S)-quinuclidin-3-yl (5-(benzofuran-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 157 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276197 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276197&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309461 378157869 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166269 CC1(C)Cc2cc(-c3cc4ccccc4o3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H30N2O3/c1-27(2)15-20-13-19(23-14-18-5-3-4-6-22(18)31-23)7-8-21(20)25(27)28-26(30)32-24-16-29-11-9-17(24)10-12-29/h3-8,13-14,17,24-25H,9-12,15-16H2,1-2H3,(H,28,30) IOBACOGYGRKFNX-UHFFFAOYSA-N 276198 (S)-quinuclidin-3-yl (5-(benzofuran-2-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 158 Mannosyl-oligosaccharide glucosidase 3.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276198 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276198&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309464 378157870 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 166270 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C26H32N2O3/c1-26(2)15-20-14-19(17-4-7-21(30-3)8-5-17)6-9-22(20)24(26)27-25(29)31-23-16-28-12-10-18(23)11-13-28/h4-9,14,18,23-24H,10-13,15-16H2,1-3H3,(H,27,29) SMMYMQKPIZWMJT-UHFFFAOYSA-N 276199 (S)-quinuclidin-3-yl (5-(4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 159 Mannosyl-oligosaccharide glucosidase 4.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276199 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276199&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311755 378157871 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167199 CCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C27H34N2O3/c1-4-31-22-8-5-18(6-9-22)20-7-10-23-21(15-20)16-27(2,3)25(23)28-26(30)32-24-17-29-13-11-19(24)12-14-29/h5-10,15,19,24-25H,4,11-14,16-17H2,1-3H3,(H,28,30) KFOJWNOTBSGZOG-UHFFFAOYSA-N 276200 (S)-quinuclidin-3-yl (5-(4-ethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 160 Mannosyl-oligosaccharide glucosidase 2.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276200 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276200&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309463 378157872 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167200 CC(C)Cc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H38N2O2/c1-19(2)15-20-5-7-21(8-6-20)23-9-10-25-24(16-23)17-29(3,4)27(25)30-28(32)33-26-18-31-13-11-22(26)12-14-31/h5-10,16,19,22,26-27H,11-15,17-18H2,1-4H3,(H,30,32) KOTNGMMTDHNRER-UHFFFAOYSA-N 276201 (S)-quinuclidin-3-yl (5-(4-isobutylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 161 Mannosyl-oligosaccharide glucosidase 1.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276201 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276201&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130311715 378157873 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167201 COc1c(Cl)ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1Cl InChI=1S/C26H30Cl2N2O3/c1-26(2)13-17-12-16(18-6-7-20(27)23(32-3)22(18)28)4-5-19(17)24(26)29-25(31)33-21-14-30-10-8-15(21)9-11-30/h4-7,12,15,21,24H,8-11,13-14H2,1-3H3,(H,29,31) GRKXOEXXPSPSNO-UHFFFAOYSA-N 276202 (S)-quinuclidin-3-yl (5-(2,4-dichloro-3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 162 Mannosyl-oligosaccharide glucosidase 7.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276202 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276202&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309468 378157874 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167202 CCCc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C28H36N2O2/c1-4-5-19-6-8-20(9-7-19)22-10-11-24-23(16-22)17-28(2,3)26(24)29-27(31)32-25-18-30-14-12-21(25)13-15-30/h6-11,16,21,25-26H,4-5,12-15,17-18H2,1-3H3,(H,29,31) NEMJNJLWNNTONV-UHFFFAOYSA-N 276203 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(4-propylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 163 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276203 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276203&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309466 378157875 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167203 CCCCc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H38N2O2/c1-4-5-6-20-7-9-21(10-8-20)23-11-12-25-24(17-23)18-29(2,3)27(25)30-28(32)33-26-19-31-15-13-22(26)14-16-31/h7-12,17,22,26-27H,4-6,13-16,18-19H2,1-3H3,(H,30,32) IMUUEOMJGUOGOC-UHFFFAOYSA-N 276204 (S)-quinuclidin-3-yl (5-(4-butylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 164 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276204 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276204&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309471 378157876 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167204 COc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1OC InChI=1S/C27H34N2O4/c1-27(2)15-19-14-18(20-6-5-7-22(31-3)24(20)32-4)8-9-21(19)25(27)28-26(30)33-23-16-29-12-10-17(23)11-13-29/h5-9,14,17,23,25H,10-13,15-16H2,1-4H3,(H,28,30) KJYYRAHVJVKFAV-UHFFFAOYSA-N 276205 (S)-quinuclidin-3-yl (5-(2,3-dimethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 165 Mannosyl-oligosaccharide glucosidase 13.7 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276205 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276205&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309469 378157877 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167205 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(OC)c1 InChI=1S/C27H34N2O4/c1-27(2)15-19-13-18(21-8-6-20(31-3)14-23(21)32-4)5-7-22(19)25(27)28-26(30)33-24-16-29-11-9-17(24)10-12-29/h5-8,13-14,17,24-25H,9-12,15-16H2,1-4H3,(H,28,30) JEJGEZBLTIRDHK-UHFFFAOYSA-N 276206 (S)-quinuclidin-3-yl (5-(2,4-dimethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 166 Mannosyl-oligosaccharide glucosidase 1.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276206 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276206&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309470 378157878 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167206 COc1ccc(OC)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O4/c1-27(2)15-19-13-18(22-14-20(31-3)6-8-23(22)32-4)5-7-21(19)25(27)28-26(30)33-24-16-29-11-9-17(24)10-12-29/h5-8,13-14,17,24-25H,9-12,15-16H2,1-4H3,(H,28,30) HLKYUGCZTDJNCR-UHFFFAOYSA-N 276207 (S)-quinuclidin-3-yl (5-(2,5-dimethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 167 Mannosyl-oligosaccharide glucosidase 0.500 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276207 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276207&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309472 378157879 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167207 COc1cccc(OC)c1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H34N2O4/c1-27(2)15-19-14-18(24-21(31-3)6-5-7-22(24)32-4)8-9-20(19)25(27)28-26(30)33-23-16-29-12-10-17(23)11-13-29/h5-9,14,17,23,25H,10-13,15-16H2,1-4H3,(H,28,30) IFPIFXZRNCNWLS-UHFFFAOYSA-N 276208 (S)-quinuclidin-3-yl (5-(2,6-dimethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 168 Mannosyl-oligosaccharide glucosidase 2.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276208 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276208&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309473 378157880 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167208 COc1cc(OC)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O4/c1-27(2)15-20-11-18(19-12-21(31-3)14-22(13-19)32-4)5-6-23(20)25(27)28-26(30)33-24-16-29-9-7-17(24)8-10-29/h5-6,11-14,17,24-25H,7-10,15-16H2,1-4H3,(H,28,30) LELKQCZIXJQOFS-UHFFFAOYSA-N 276209 (S)-quinuclidin-3-yl (5-(3,5-dimethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 169 Mannosyl-oligosaccharide glucosidase 1.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276209 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276209&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309474 378157881 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167209 CCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C(F)(F)F InChI=1S/C28H33F3N2O3/c1-4-35-23-8-6-19(14-22(23)28(29,30)31)18-5-7-21-20(13-18)15-27(2,3)25(21)32-26(34)36-24-16-33-11-9-17(24)10-12-33/h5-8,13-14,17,24-25H,4,9-12,15-16H2,1-3H3,(H,32,34) NGPATADPDNWQAZ-UHFFFAOYSA-N 276210 (S)-quinuclidin-3-yl (5-(4-ethoxy-3-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 170 Mannosyl-oligosaccharide glucosidase 6.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276210 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276210&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302402 378157882 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167210 COc1cc(F)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1F InChI=1S/C26H30F2N2O3/c1-26(2)13-17-10-16(19-11-21(28)22(32-3)12-20(19)27)4-5-18(17)24(26)29-25(31)33-23-14-30-8-6-15(23)7-9-30/h4-5,10-12,15,23-24H,6-9,13-14H2,1-3H3,(H,29,31) VHTFSPUZGVEQPV-UHFFFAOYSA-N 276211 (S)-quinuclidin-3-yl (5-(2,5-difluoro-4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 171 Mannosyl-oligosaccharide glucosidase 2.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276211 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276211&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309475 378157883 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167211 CC(C)Oc1ccc(F)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C28H35FN2O3/c1-17(2)33-21-6-8-24(29)23(14-21)19-5-7-22-20(13-19)15-28(3,4)26(22)30-27(32)34-25-16-31-11-9-18(25)10-12-31/h5-8,13-14,17-18,25-26H,9-12,15-16H2,1-4H3,(H,30,32) OFSIFMAVNANBOW-UHFFFAOYSA-N 276212 (S)-quinuclidin-3-yl (5-(2-fluoro-5-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 172 Mannosyl-oligosaccharide glucosidase 1.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276212 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276212&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309483 378157884 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167212 CCCOc1c(C)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C InChI=1S/C30H40N2O3/c1-6-13-34-27-19(2)14-23(15-20(27)3)22-7-8-25-24(16-22)17-30(4,5)28(25)31-29(33)35-26-18-32-11-9-21(26)10-12-32/h7-8,14-16,21,26,28H,6,9-13,17-18H2,1-5H3,(H,31,33) COBUMULQBSIHBD-UHFFFAOYSA-N 276213 (S)-quinuclidin-3-yl (5-(3,5-dimethyl-4-propoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 173 Mannosyl-oligosaccharide glucosidase 7.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276213 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276213&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302246 378157885 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167213 CCOc1c(C)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C InChI=1S/C29H38N2O3/c1-6-33-26-18(2)13-22(14-19(26)3)21-7-8-24-23(15-21)16-29(4,5)27(24)30-28(32)34-25-17-31-11-9-20(25)10-12-31/h7-8,13-15,20,25,27H,6,9-12,16-17H2,1-5H3,(H,30,32) XDCSHXVZSHMGHM-UHFFFAOYSA-N 276217 (S)-quinuclidin-3-yl (5-(4-ethoxy-3,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 174 Mannosyl-oligosaccharide glucosidase 4.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276217 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276217&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309497 378157887 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167214 CCc1ccccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H34N2O2/c1-4-18-7-5-6-8-22(18)20-9-10-23-21(15-20)16-27(2,3)25(23)28-26(30)31-24-17-29-13-11-19(24)12-14-29/h5-10,15,19,24-25H,4,11-14,16-17H2,1-3H3,(H,28,30) PGZNSRCWLUGPPO-UHFFFAOYSA-N 276218 (S)-quinuclidin-3-yl (5-(2-ethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 175 Mannosyl-oligosaccharide glucosidase 2.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276218 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276218&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309498 378157888 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167215 COc1ccccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H32N2O3/c1-26(2)15-19-14-18(20-6-4-5-7-22(20)30-3)8-9-21(19)24(26)27-25(29)31-23-16-28-12-10-17(23)11-13-28/h4-9,14,17,23-24H,10-13,15-16H2,1-3H3,(H,27,29) DLXCGUSXRFQATR-UHFFFAOYSA-N 276219 (S)-quinuclidin-3-yl (5-(2-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 176 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276219 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276219&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309499 378157889 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167216 CCOc1ccccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H34N2O3/c1-4-31-23-8-6-5-7-21(23)19-9-10-22-20(15-19)16-27(2,3)25(22)28-26(30)32-24-17-29-13-11-18(24)12-14-29/h5-10,15,18,24-25H,4,11-14,16-17H2,1-3H3,(H,28,30) GPLUGHKHCSZBFS-UHFFFAOYSA-N 276220 (S)-quinuclidin-3-yl (5-(2-ethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 177 Mannosyl-oligosaccharide glucosidase 3.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276220 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276220&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309500 378157890 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167217 CC1(C)Cc2cc(-c3cc(OC(F)(F)F)ccc3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28ClF3N2O3/c1-25(2)13-17-11-16(20-12-18(4-6-21(20)27)35-26(28,29)30)3-5-19(17)23(25)31-24(33)34-22-14-32-9-7-15(22)8-10-32/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,31,33) UYUJMAQGEPYRNF-UHFFFAOYSA-N 276221 (S)-quinuclidin-3-yl (5-(2-chloro-5-(trifluoromethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 178 Mannosyl-oligosaccharide glucosidase 3.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276221 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276221&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309506 378157891 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167218 COc1cc(F)ccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31FN2O3/c1-26(2)14-18-12-17(20-7-5-19(27)13-22(20)31-3)4-6-21(18)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) CTBLSVWYONCPJA-UHFFFAOYSA-N 276222 (S)-quinuclidin-3-yl (5-(4-fluoro-2-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 179 Mannosyl-oligosaccharide glucosidase 4.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276222 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276222&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309501 378157892 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167219 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(C)c1 InChI=1S/C27H34N2O3/c1-17-13-21(31-4)6-8-22(17)19-5-7-23-20(14-19)15-27(2,3)25(23)28-26(30)32-24-16-29-11-9-18(24)10-12-29/h5-8,13-14,18,24-25H,9-12,15-16H2,1-4H3,(H,28,30) AQAVVRQKIXQYFB-UHFFFAOYSA-N 276223 (S)-quinuclidin-3-yl (5-(4-methoxy-2-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 180 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276223 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276223&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309502 378157893 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167220 CC(C)(C)OCc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C30H40N2O3/c1-29(2,3)34-19-20-6-8-21(9-7-20)23-10-11-25-24(16-23)17-30(4,5)27(25)31-28(33)35-26-18-32-14-12-22(26)13-15-32/h6-11,16,22,26-27H,12-15,17-19H2,1-5H3,(H,31,33) BKBDTSVKRAKTBX-UHFFFAOYSA-N 276224 (S)-quinuclidin-3-yl (5-(4-(tert-butoxymethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 181 Mannosyl-oligosaccharide glucosidase 0.300 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276224 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276224&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309503 378157894 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167221 CC1(C)Cc2cc(-c3cccc(C(F)(F)F)c3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28ClF3N2O2/c1-25(2)13-17-12-16(18-4-3-5-20(22(18)27)26(28,29)30)6-7-19(17)23(25)31-24(33)34-21-14-32-10-8-15(21)9-11-32/h3-7,12,15,21,23H,8-11,13-14H2,1-2H3,(H,31,33) IBGXQKUCUFECGH-UHFFFAOYSA-N 276225 (S)-quinuclidin-3-yl (5-(2-chloro-3-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 182 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276225 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276225&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309504 378157895 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167222 CC1(C)Cc2cc(-c3ccc(C(F)(F)F)cc3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28ClF3N2O2/c1-25(2)13-17-11-16(19-6-4-18(12-21(19)27)26(28,29)30)3-5-20(17)23(25)31-24(33)34-22-14-32-9-7-15(22)8-10-32/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,31,33) PUYFELZTWXZPGG-UHFFFAOYSA-N 276226 (S)-quinuclidin-3-yl (5-(2-chloro-4-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 183 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276226 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276226&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309505 378157896 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167223 COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(OC)n1 InChI=1S/C26H33N3O4/c1-26(2)14-18-13-17(20-7-8-22(31-3)27-24(20)32-4)5-6-19(18)23(26)28-25(30)33-21-15-29-11-9-16(21)10-12-29/h5-8,13,16,21,23H,9-12,14-15H2,1-4H3,(H,28,30) QSGBVSGZWQWYIM-UHFFFAOYSA-N 276228 (S)-quinuclidin-3-yl (5-(2,6-dimethoxypyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 184 Mannosyl-oligosaccharide glucosidase 6.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276228 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276228&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309508 378157898 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167224 CC1(C)Cc2cc(-c3ccc(OCC4CC4)nc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H35N3O3/c1-28(2)14-22-13-20(21-6-8-25(29-15-21)33-17-18-3-4-18)5-7-23(22)26(28)30-27(32)34-24-16-31-11-9-19(24)10-12-31/h5-8,13,15,18-19,24,26H,3-4,9-12,14,16-17H2,1-2H3,(H,30,32) UCMIQZPUQCFNLT-UHFFFAOYSA-N 276230 (S)-quinuclidin-3-yl (5-(6-(cyclopropylmethoxy)pyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 185 Mannosyl-oligosaccharide glucosidase 0.500 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276230 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276230&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309510 378157900 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167225 CC1(C)Cc2cc(-c3cc4ccccc4s3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H30N2O2S/c1-27(2)15-20-13-19(24-14-18-5-3-4-6-23(18)32-24)7-8-21(20)25(27)28-26(30)31-22-16-29-11-9-17(22)10-12-29/h3-8,13-14,17,22,25H,9-12,15-16H2,1-2H3,(H,28,30) OGMIOQQOGCRAGA-UHFFFAOYSA-N 276231 (S)-quinuclidin-3-yl (5-(benzo[b]thiophen-2-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 186 Mannosyl-oligosaccharide glucosidase 9.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276231 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276231&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309509 378157901 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167226 CC(C)(C)Oc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccn1 InChI=1S/C28H37N3O3/c1-27(2,3)34-24-15-20(8-11-29-24)19-6-7-22-21(14-19)16-28(4,5)25(22)30-26(32)33-23-17-31-12-9-18(23)10-13-31/h6-8,11,14-15,18,23,25H,9-10,12-13,16-17H2,1-5H3,(H,30,32) MUFPXQUESVUAAB-UHFFFAOYSA-N 276232 (S)-quinuclidin-3-yl (5-(2-(tert-butoxy)pyridin-4-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 187 Mannosyl-oligosaccharide glucosidase 4.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276232 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276232&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309511 378157902 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167227 COc1ncc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C(F)(F)F InChI=1S/C26H30F3N3O3/c1-25(2)12-17-10-16(18-11-20(26(27,28)29)23(34-3)30-13-18)4-5-19(17)22(25)31-24(33)35-21-14-32-8-6-15(21)7-9-32/h4-5,10-11,13,15,21-22H,6-9,12,14H2,1-3H3,(H,31,33) SSZPVEBRRBKLMC-UHFFFAOYSA-N 276233 (S)-quinuclidin-3-yl (5-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 188 Mannosyl-oligosaccharide glucosidase 8.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276233 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276233&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309512 378157903 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167228 COc1ccc2cc(-c3ccc4c(c3)CC(C)(C)C4NC(=O)O[C@H]3CN4CCC3CC4)ccc2c1 InChI=1S/C30H34N2O3/c1-30(2)17-24-15-22(20-4-5-23-16-25(34-3)8-6-21(23)14-20)7-9-26(24)28(30)31-29(33)35-27-18-32-12-10-19(27)11-13-32/h4-9,14-16,19,27-28H,10-13,17-18H2,1-3H3,(H,31,33) VPGZTYVVVILJHZ-UHFFFAOYSA-N 276234 (S)-quinuclidin-3-yl (5-(6-methoxynaphthalen-2-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 189 Mannosyl-oligosaccharide glucosidase 2.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276234 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276234&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309514 378157904 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167229 CC1(C)Cc2cc(-c3cccc(-c4ccccc4)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C31H34N2O2/c1-31(2)19-26-18-25(24-10-6-9-23(17-24)21-7-4-3-5-8-21)11-12-27(26)29(31)32-30(34)35-28-20-33-15-13-22(28)14-16-33/h3-12,17-18,22,28-29H,13-16,19-20H2,1-2H3,(H,32,34) XZZBDKWXTQDDKT-UHFFFAOYSA-N 276235 (S)-quinuclidin-3-yl (5-([1,1'-biphenyl]-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 190 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276235 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276235&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309513 378157905 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167230 CC1(C)Cc2cc(-c3ccc4nccnc4c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H30N4O2/c1-27(2)15-20-13-18(19-4-6-22-23(14-19)29-10-9-28-22)3-5-21(20)25(27)30-26(32)33-24-16-31-11-7-17(24)8-12-31/h3-6,9-10,13-14,17,24-25H,7-8,11-12,15-16H2,1-2H3,(H,30,32) JWYBWRVFFLLPHU-UHFFFAOYSA-N 276236 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(quinoxalin-6-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 191 Mannosyl-oligosaccharide glucosidase 9.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276236 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276236&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309515 378157906 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167231 Cc1cc(C)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O2/c1-17-11-18(2)13-21(12-17)20-5-6-23-22(14-20)15-27(3,4)25(23)28-26(30)31-24-16-29-9-7-19(24)8-10-29/h5-6,11-14,19,24-25H,7-10,15-16H2,1-4H3,(H,28,30) PSZCTTYVBBHALB-UHFFFAOYSA-N 276238 (S)-quinuclidin-3-yl (5-(3,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 192 Mannosyl-oligosaccharide glucosidase 3.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276238 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276238&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309517 378157908 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167232 CC1(C)Cc2cc(-c3ccco3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C23H28N2O3/c1-23(2)13-17-12-16(19-4-3-11-27-19)5-6-18(17)21(23)24-22(26)28-20-14-25-9-7-15(20)8-10-25/h3-6,11-12,15,20-21H,7-10,13-14H2,1-2H3,(H,24,26) QWOZXUYEIGNSBM-UHFFFAOYSA-N 276239 (S)-quinuclidin-3-yl (5-(furan-2-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 193 Mannosyl-oligosaccharide glucosidase 2.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276239 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276239&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309518 378157909 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167233 Cc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc(C)c1OC(C)C InChI=1S/C30H40N2O3/c1-18(2)34-27-19(3)13-23(14-20(27)4)22-7-8-25-24(15-22)16-30(5,6)28(25)31-29(33)35-26-17-32-11-9-21(26)10-12-32/h7-8,13-15,18,21,26,28H,9-12,16-17H2,1-6H3,(H,31,33) RWNBPUQFHMPNES-UHFFFAOYSA-N 276240 (S)-quinuclidin-3-yl (5-(4-isopropoxy-3,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 194 Mannosyl-oligosaccharide glucosidase 10.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276240 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276240&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309519 378157910 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167234 COc1c(C)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C InChI=1S/C28H36N2O3/c1-17-12-21(13-18(2)25(17)32-5)20-6-7-23-22(14-20)15-28(3,4)26(23)29-27(31)33-24-16-30-10-8-19(24)9-11-30/h6-7,12-14,19,24,26H,8-11,15-16H2,1-5H3,(H,29,31) CVFMNHDYDQRTGJ-UHFFFAOYSA-N 276241 (S)-quinuclidin-3-yl (5-(4-methoxy-3,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 195 Mannosyl-oligosaccharide glucosidase 6.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276241 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276241&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309520 378157911 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167235 CC(C)Oc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cn1 InChI=1S/C27H35N3O3/c1-17(2)32-24-8-6-20(15-28-24)19-5-7-22-21(13-19)14-27(3,4)25(22)29-26(31)33-23-16-30-11-9-18(23)10-12-30/h5-8,13,15,17-18,23,25H,9-12,14,16H2,1-4H3,(H,29,31) UTKACZGGUIBKTP-UHFFFAOYSA-N 276242 (S)-quinuclidin-3-yl (5-(6-isopropoxypyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 196 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276242 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276242&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309521 378157912 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167236 CC1(C)Cc2cc(-c3cccc(OCCF)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H33FN2O3/c1-27(2)16-21-14-20(19-4-3-5-22(15-19)32-13-10-28)6-7-23(21)25(27)29-26(31)33-24-17-30-11-8-18(24)9-12-30/h3-7,14-15,18,24-25H,8-13,16-17H2,1-2H3,(H,29,31) FKUJBPGLZGQXSV-UHFFFAOYSA-N 276243 (S)-quinuclidin-3-yl (5-(3-(2-fluoroethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 197 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276243 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276243&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309522 378157913 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167237 CCOc1ccc(C)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H36N2O3/c1-5-32-24-9-6-18(2)14-23(24)20-7-8-22-21(15-20)16-28(3,4)26(22)29-27(31)33-25-17-30-12-10-19(25)11-13-30/h6-9,14-15,19,25-26H,5,10-13,16-17H2,1-4H3,(H,29,31) AYVCJMOTXIVKLN-UHFFFAOYSA-N 276244 (S)-quinuclidin-3-yl (5-(2-ethoxy-5-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 198 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276244 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276244&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309523 378157914 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167238 CCCOc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C28H36N2O3/c1-4-14-32-23-7-5-6-20(16-23)21-8-9-24-22(15-21)17-28(2,3)26(24)29-27(31)33-25-18-30-12-10-19(25)11-13-30/h5-9,15-16,19,25-26H,4,10-14,17-18H2,1-3H3,(H,29,31) CLJPWYDRABDYAO-UHFFFAOYSA-N 276245 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(3-propoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 199 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276245 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276245&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302348 378157915 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167239 COc1ccc(C)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H34N2O3/c1-17-5-8-23(31-4)22(13-17)19-6-7-21-20(14-19)15-27(2,3)25(21)28-26(30)32-24-16-29-11-9-18(24)10-12-29/h5-8,13-14,18,24-25H,9-12,15-16H2,1-4H3,(H,28,30) GUVDGAJVDFKVOS-UHFFFAOYSA-N 276246 (S)-quinuclidin-3-yl (5-(2-methoxy-5-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 200 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276246 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276246&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309524 378157916 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167240 CCCCOc1ccc(F)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H37FN2O3/c1-4-5-14-34-25-9-7-22(30)16-24(25)20-6-8-23-21(15-20)17-29(2,3)27(23)31-28(33)35-26-18-32-12-10-19(26)11-13-32/h6-9,15-16,19,26-27H,4-5,10-14,17-18H2,1-3H3,(H,31,33) XZATWHUNJDMYLD-UHFFFAOYSA-N 276247 (S)-quinuclidin-3-yl (5-(2-butoxy-5-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 201 Mannosyl-oligosaccharide glucosidase 3.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276247 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276247&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 136214426 378157917 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167241 CCCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1Cl InChI=1S/C29H37ClN2O3/c1-4-5-14-34-25-9-7-21(16-24(25)30)20-6-8-23-22(15-20)17-29(2,3)27(23)31-28(33)35-26-18-32-12-10-19(26)11-13-32/h6-9,15-16,19,26-27H,4-5,10-14,17-18H2,1-3H3,(H,31,33) AOFUBGAXKZJJNH-UHFFFAOYSA-N 276248 (S)-quinuclidin-3-yl (5-(4-butoxy-3-chlorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 202 Mannosyl-oligosaccharide glucosidase 6.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276248 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276248&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309525 378157918 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167242 CCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(OCCC)c1 InChI=1S/C31H42N2O4/c1-5-15-35-24-8-10-25(27(18-24)36-16-6-2)22-7-9-26-23(17-22)19-31(3,4)29(26)32-30(34)37-28-20-33-13-11-21(28)12-14-33/h7-10,17-18,21,28-29H,5-6,11-16,19-20H2,1-4H3,(H,32,34) YHLLGNREMDKWGQ-UHFFFAOYSA-N 276249 (S)-quinuclidin-3-yl (5-(2,4-dipropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 203 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276249 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276249&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309526 378157919 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167243 CCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1Cl InChI=1S/C27H33ClN2O3/c1-4-32-23-8-6-19(14-22(23)28)18-5-7-21-20(13-18)15-27(2,3)25(21)29-26(31)33-24-16-30-11-9-17(24)10-12-30/h5-8,13-14,17,24-25H,4,9-12,15-16H2,1-3H3,(H,29,31) NZNFLNXMZYIZHF-UHFFFAOYSA-N 276250 (S)-quinuclidin-3-yl (5-(3-chloro-4-ethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 204 Mannosyl-oligosaccharide glucosidase 8.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276250 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276250&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302223 378157920 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167244 CC(C)COc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C29H38N2O3/c1-19(2)18-33-24-7-5-6-21(15-24)22-8-9-25-23(14-22)16-29(3,4)27(25)30-28(32)34-26-17-31-12-10-20(26)11-13-31/h5-9,14-15,19-20,26-27H,10-13,16-18H2,1-4H3,(H,30,32) GCMKJTIAWBWWJD-UHFFFAOYSA-N 276251 (S)-quinuclidin-3-yl (5-(3-isobutoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 205 Mannosyl-oligosaccharide glucosidase 1.000 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276251 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276251&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309527 378157921 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167245 CCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(C)c1 InChI=1S/C28H36N2O3/c1-5-32-22-7-9-23(18(2)14-22)20-6-8-24-21(15-20)16-28(3,4)26(24)29-27(31)33-25-17-30-12-10-19(25)11-13-30/h6-9,14-15,19,25-26H,5,10-13,16-17H2,1-4H3,(H,29,31) PDAIAFWLTQMYLV-UHFFFAOYSA-N 276252 (S)-quinuclidin-3-yl (5-(4-ethoxy-2-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 206 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276252 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276252&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302422 378157922 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167246 CCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1Cl InChI=1S/C28H35ClN2O3/c1-4-13-33-24-8-6-20(15-23(24)29)19-5-7-22-21(14-19)16-28(2,3)26(22)30-27(32)34-25-17-31-11-9-18(25)10-12-31/h5-8,14-15,18,25-26H,4,9-13,16-17H2,1-3H3,(H,30,32) BYJCCKWTTZWKJS-UHFFFAOYSA-N 276253 (S)-quinuclidin-3-yl (5-(3-chloro-4-propoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 207 Mannosyl-oligosaccharide glucosidase 6.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276253 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276253&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309528 378157923 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167247 CC(C)Oc1ccc(F)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H35FN2O3/c1-17(2)33-24-8-6-21(29)14-23(24)19-5-7-22-20(13-19)15-28(3,4)26(22)30-27(32)34-25-16-31-11-9-18(25)10-12-31/h5-8,13-14,17-18,25-26H,9-12,15-16H2,1-4H3,(H,30,32) CRQIODOJZHGMGE-UHFFFAOYSA-N 276254 (S)-quinuclidin-3-yl (5-(5-fluoro-2-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 208 Mannosyl-oligosaccharide glucosidase 3.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276254 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276254&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309529 378157924 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167248 CC(C)Oc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1F InChI=1S/C28H35FN2O3/c1-17(2)33-24-8-6-20(14-23(24)29)19-5-7-22-21(13-19)15-28(3,4)26(22)30-27(32)34-25-16-31-11-9-18(25)10-12-31/h5-8,13-14,17-18,25-26H,9-12,15-16H2,1-4H3,(H,30,32) JTEMCRDTMRDKPS-UHFFFAOYSA-N 276255 (S)-quinuclidin-3-yl (5-(3-fluoro-4-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 209 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276255 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276255&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309530 378157925 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167249 COc1ccc(Cl)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31ClN2O3/c1-26(2)14-18-12-17(21-13-19(27)5-7-22(21)31-3)4-6-20(18)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) JYJKSBQYJNRDIL-UHFFFAOYSA-N 276256 (S)-quinuclidin-3-yl (5-(5-chloro-2-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 210 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276256 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276256&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302377 378157926 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167250 Cc1ccc(F)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H31FN2O2/c1-16-4-7-22(27)21(12-16)18-5-6-20-19(13-18)14-26(2,3)24(20)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) UAXRAAOPXSKEDA-UHFFFAOYSA-N 276257 (S)-quinuclidin-3-yl (5-(2-fluoro-5-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 211 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276257 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276257&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309532 378157927 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167251 CCOc1ccc(Cl)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H33ClN2O3/c1-4-32-23-8-6-20(28)14-22(23)18-5-7-21-19(13-18)15-27(2,3)25(21)29-26(31)33-24-16-30-11-9-17(24)10-12-30/h5-8,13-14,17,24-25H,4,9-12,15-16H2,1-3H3,(H,29,31) IMPDFFBYKBUOKC-UHFFFAOYSA-N 276258 (S)-quinuclidin-3-yl (5-(5-chloro-2-ethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 212 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276258 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276258&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309531 378157928 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167252 CCCOc1ccc(F)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H35FN2O3/c1-4-13-33-24-8-6-21(29)15-23(24)19-5-7-22-20(14-19)16-28(2,3)26(22)30-27(32)34-25-17-31-11-9-18(25)10-12-31/h5-8,14-15,18,25-26H,4,9-13,16-17H2,1-3H3,(H,30,32) WGRUFGYICZHUTB-UHFFFAOYSA-N 276259 (S)-quinuclidin-3-yl (5-(5-fluoro-2-propoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 213 Mannosyl-oligosaccharide glucosidase 2.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276259 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276259&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309533 378157929 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167253 CCCOc1cccc(F)c1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H35FN2O3/c1-4-14-33-23-7-5-6-22(29)25(23)19-8-9-21-20(15-19)16-28(2,3)26(21)30-27(32)34-24-17-31-12-10-18(24)11-13-31/h5-9,15,18,24,26H,4,10-14,16-17H2,1-3H3,(H,30,32) NEFDSSDMNVMQCN-UHFFFAOYSA-N 276260 (S)-quinuclidin-3-yl (5-(2-fluoro-6-propoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 214 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276260 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276260&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309534 378157930 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167254 Cc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1F InChI=1S/C26H31FN2O2/c1-16-4-5-19(13-22(16)27)18-6-7-21-20(12-18)14-26(2,3)24(21)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) VJHWHBBZHOTICT-UHFFFAOYSA-N 276261 (S)-quinuclidin-3-yl (5-(3-fluoro-4-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 215 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276261 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276261&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309535 378157931 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167255 CCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1F InChI=1S/C28H35FN2O3/c1-4-13-33-24-8-6-20(15-23(24)29)19-5-7-22-21(14-19)16-28(2,3)26(22)30-27(32)34-25-17-31-11-9-18(25)10-12-31/h5-8,14-15,18,25-26H,4,9-13,16-17H2,1-3H3,(H,30,32) DTZHZUGBDBQIDQ-UHFFFAOYSA-N 276262 (S)-quinuclidin-3-yl (5-(3-fluoro-4-propoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 216 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276262 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276262&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309536 378157932 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167256 CC(C)Oc1ccc(Cl)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H35ClN2O3/c1-17(2)33-24-8-6-21(29)14-23(24)19-5-7-22-20(13-19)15-28(3,4)26(22)30-27(32)34-25-16-31-11-9-18(25)10-12-31/h5-8,13-14,17-18,25-26H,9-12,15-16H2,1-4H3,(H,30,32) GQMGOYMRYLRJHZ-UHFFFAOYSA-N 276263 (S)-quinuclidin-3-yl (5-(5-chloro-2-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 217 Mannosyl-oligosaccharide glucosidase 2.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276263 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276263&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309537 378157933 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167257 CCCCOc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C29H38N2O3/c1-4-5-15-33-24-8-6-7-21(17-24)22-9-10-25-23(16-22)18-29(2,3)27(25)30-28(32)34-26-19-31-13-11-20(26)12-14-31/h6-10,16-17,20,26-27H,4-5,11-15,18-19H2,1-3H3,(H,30,32) BFYURJVAPMTABU-UHFFFAOYSA-N 276264 (S)-quinuclidin-3-yl (5-(3-butoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 218 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276264 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276264&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309538 378157934 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167258 Cc1cc(F)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H31FN2O2/c1-16-10-19(13-21(27)11-16)18-4-5-22-20(12-18)14-26(2,3)24(22)28-25(30)31-23-15-29-8-6-17(23)7-9-29/h4-5,10-13,17,23-24H,6-9,14-15H2,1-3H3,(H,28,30) PAEMNBTWUNAJKO-UHFFFAOYSA-N 276265 (S)-quinuclidin-3-yl (5-(3-fluoro-5-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 219 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276265 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276265&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309541 378157935 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167259 Cc1ccc(F)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31FN2O2/c1-16-4-6-20(27)13-22(16)18-5-7-21-19(12-18)14-26(2,3)24(21)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) HUBBKQLZCPJXRQ-UHFFFAOYSA-N 276266 (S)-quinuclidin-3-yl (5-(5-fluoro-2-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 220 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276266 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276266&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309539 378157936 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167260 CC1(C)Cc2cc(-c3cc(C(F)(F)F)ccc3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28ClF3N2O2/c1-25(2)13-17-11-16(20-12-18(26(28,29)30)4-6-21(20)27)3-5-19(17)23(25)31-24(33)34-22-14-32-9-7-15(22)8-10-32/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,31,33) UBJFIGJGTKHCQD-UHFFFAOYSA-N 276267 (S)-quinuclidin-3-yl (5-(2-chloro-5-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 221 Mannosyl-oligosaccharide glucosidase 1.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276267 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276267&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309540 378157937 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167261 COc1cc(F)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H31FN2O3/c1-26(2)14-19-10-17(18-11-20(27)13-21(12-18)31-3)4-5-22(19)24(26)28-25(30)32-23-15-29-8-6-16(23)7-9-29/h4-5,10-13,16,23-24H,6-9,14-15H2,1-3H3,(H,28,30) AQIIQDTYIQMVMT-UHFFFAOYSA-N 276268 (S)-quinuclidin-3-yl (5-(3-fluoro-5-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 222 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276268 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276268&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309542 378157938 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167262 Cc1ccc(Cl)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H31ClN2O2/c1-16-4-7-22(27)21(12-16)18-5-6-20-19(13-18)14-26(2,3)24(20)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) LFBPUBREJSHLPV-UHFFFAOYSA-N 276269 (S)-quinuclidin-3-yl (5-(2-chloro-5-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 223 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276269 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276269&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309546 378157939 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167263 COc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc(C(F)(F)F)c1 InChI=1S/C27H31F3N2O3/c1-26(2)14-19-10-17(18-11-20(27(28,29)30)13-21(12-18)34-3)4-5-22(19)24(26)31-25(33)35-23-15-32-8-6-16(23)7-9-32/h4-5,10-13,16,23-24H,6-9,14-15H2,1-3H3,(H,31,33) KSIPEAVCKHHVAB-UHFFFAOYSA-N 276270 (S)-quinuclidin-3-yl (5-(3-methoxy-5-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 224 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276270 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276270&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309543 378157940 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167264 CC1(C)Cc2cc(-c3ccc(F)cc3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28ClFN2O2/c1-25(2)13-17-11-16(19-6-4-18(27)12-21(19)26)3-5-20(17)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) PCHMEUMQASKEOM-UHFFFAOYSA-N 276271 (S)-quinuclidin-3-yl (5-(2-chloro-4-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 225 Mannosyl-oligosaccharide glucosidase 2.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276271 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276271&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309547 378157941 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167265 COc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccc1F InChI=1S/C26H31FN2O3/c1-26(2)14-19-12-17(18-5-7-21(27)22(13-18)31-3)4-6-20(19)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) FJYCLYMFSOMULI-UHFFFAOYSA-N 276272 (S)-quinuclidin-3-yl (5-(4-fluoro-3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 226 Mannosyl-oligosaccharide glucosidase 6.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276272 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276272&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309544 378157942 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167266 Cc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C InChI=1S/C27H34N2O2/c1-17-5-6-20(13-18(17)2)21-7-8-23-22(14-21)15-27(3,4)25(23)28-26(30)31-24-16-29-11-9-19(24)10-12-29/h5-8,13-14,19,24-25H,9-12,15-16H2,1-4H3,(H,28,30) FUTYVKMJLXRIFQ-UHFFFAOYSA-N 276273 (S)-quinuclidin-3-yl (5-(3,4-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 227 Mannosyl-oligosaccharide glucosidase 2.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276273 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276273&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309545 378157943 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167267 Cc1cc(F)ccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31FN2O2/c1-16-12-20(27)5-7-21(16)18-4-6-22-19(13-18)14-26(2,3)24(22)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) BEUAHAFJUYQGLI-UHFFFAOYSA-N 276274 (S)-quinuclidin-3-yl (5-(4-fluoro-2-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 228 Mannosyl-oligosaccharide glucosidase 3.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276274 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276274&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309548 378157944 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167268 CC1(C)Cc2cc(-c3ccc(C(F)(F)F)cc3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28F4N2O2/c1-25(2)13-17-11-16(19-6-4-18(12-21(19)27)26(28,29)30)3-5-20(17)23(25)31-24(33)34-22-14-32-9-7-15(22)8-10-32/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,31,33) JQXLGINIJYQBSB-UHFFFAOYSA-N 276275 (S)-quinuclidin-3-yl (5-(2-fluoro-4-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 229 Mannosyl-oligosaccharide glucosidase 4.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276275 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276275&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309549 378157945 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167269 COc1ccc(F)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C26H31FN2O3/c1-26(2)14-18-12-17(21-13-19(31-3)5-7-22(21)27)4-6-20(18)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) FRJZGVOJJGBGAK-UHFFFAOYSA-N 276276 (S)-quinuclidin-3-yl (5-(2-fluoro-5-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 230 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276276 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276276&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309550 378157946 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167270 COc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1F InChI=1S/C26H31FN2O3/c1-26(2)14-18-13-17(19-5-4-6-21(31-3)23(19)27)7-8-20(18)24(26)28-25(30)32-22-15-29-11-9-16(22)10-12-29/h4-8,13,16,22,24H,9-12,14-15H2,1-3H3,(H,28,30) CVIJZXXUWAYBLR-UHFFFAOYSA-N 276277 (S)-quinuclidin-3-yl (5-(2-fluoro-3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 231 Mannosyl-oligosaccharide glucosidase 0.500 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276277 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276277&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302291 378157947 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167271 COc1ccc(C(C)C)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O3/c1-18(2)20-7-9-25(33-5)24(15-20)21-6-8-23-22(14-21)16-29(3,4)27(23)30-28(32)34-26-17-31-12-10-19(26)11-13-31/h6-9,14-15,18-19,26-27H,10-13,16-17H2,1-5H3,(H,30,32) ICUPHIDJCFMHIE-UHFFFAOYSA-N 276278 (S)-quinuclidin-3-yl (5-(5-isopropyl-2-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 232 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276278 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276278&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302292 378157948 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167272 Cc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c(F)c1 InChI=1S/C26H31FN2O2/c1-16-4-6-20(22(27)12-16)18-5-7-21-19(13-18)14-26(2,3)24(21)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) YICSJXLIQBUDAE-UHFFFAOYSA-N 276279 (S)-quinuclidin-3-yl (5-(2-fluoro-4-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 233 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276279 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276279&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302180 378157949 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167273 COc1ccc(F)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31FN2O3/c1-26(2)14-18-12-17(21-13-19(27)5-7-22(21)31-3)4-6-20(18)24(26)28-25(30)32-23-15-29-10-8-16(23)9-11-29/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,28,30) ACCAYOMUSNUSHO-UHFFFAOYSA-N 276280 (S)-quinuclidin-3-yl (5-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 234 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276280 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276280&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302366 378157950 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167274 Cc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)co1 InChI=1S/C24H30N2O3/c1-15-10-19(14-28-15)17-4-5-20-18(11-17)12-24(2,3)22(20)25-23(27)29-21-13-26-8-6-16(21)7-9-26/h4-5,10-11,14,16,21-22H,6-9,12-13H2,1-3H3,(H,25,27) XSBZOFCOIUTODM-UHFFFAOYSA-N 276281 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(5-methylfuran-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 235 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276281 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276281&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302249 378157951 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167275 COc1c(F)cccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31FN2O3/c1-26(2)14-18-13-17(19-5-4-6-21(27)23(19)31-3)7-8-20(18)24(26)28-25(30)32-22-15-29-11-9-16(22)10-12-29/h4-8,13,16,22,24H,9-12,14-15H2,1-3H3,(H,28,30) QVDHSWBXZZXWRY-UHFFFAOYSA-N 276282 (S)-quinuclidin-3-yl (5-(3-fluoro-2-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 236 Mannosyl-oligosaccharide glucosidase 3.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276282 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276282&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302231 378157952 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167276 CC1(C)Cc2cc(-c3cccc(F)c3Cl)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28ClFN2O2/c1-25(2)13-17-12-16(18-4-3-5-20(27)22(18)26)6-7-19(17)23(25)28-24(30)31-21-14-29-10-8-15(21)9-11-29/h3-7,12,15,21,23H,8-11,13-14H2,1-2H3,(H,28,30) WMQHBSMEMHLKAH-UHFFFAOYSA-N 276283 (S)-quinuclidin-3-yl (5-(2-chloro-3-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 237 Mannosyl-oligosaccharide glucosidase 5.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276283 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276283&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302282 378157953 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167277 CC1(C)Cc2cc(-c3csc4ccccc34)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H30N2O2S/c1-27(2)14-19-13-18(22-16-32-24-6-4-3-5-21(22)24)7-8-20(19)25(27)28-26(30)31-23-15-29-11-9-17(23)10-12-29/h3-8,13,16-17,23,25H,9-12,14-15H2,1-2H3,(H,28,30) UVOKHGDNHLFKDI-UHFFFAOYSA-N 276284 (S)-quinuclidin-3-yl (5-(benzo[b]thiophen-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 238 Mannosyl-oligosaccharide glucosidase 2.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276284 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276284&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302240 378157954 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167278 CCCOc1cc(F)ccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H35FN2O3/c1-4-13-33-24-15-21(29)6-8-22(24)19-5-7-23-20(14-19)16-28(2,3)26(23)30-27(32)34-25-17-31-11-9-18(25)10-12-31/h5-8,14-15,18,25-26H,4,9-13,16-17H2,1-3H3,(H,30,32) RWLFISSUYVYAQV-UHFFFAOYSA-N 276285 (S)-quinuclidin-3-yl (5-(4-fluoro-2-propoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 239 Mannosyl-oligosaccharide glucosidase 7.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276285 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276285&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302229 378157955 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167279 Cc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc(C(C)(C)C)c1 InChI=1S/C30H40N2O2/c1-19-13-22(16-24(14-19)29(2,3)4)21-7-8-25-23(15-21)17-30(5,6)27(25)31-28(33)34-26-18-32-11-9-20(26)10-12-32/h7-8,13-16,20,26-27H,9-12,17-18H2,1-6H3,(H,31,33) GVLBGOKGPNFFRV-UHFFFAOYSA-N 276286 (S)-quinuclidin-3-yl (5-(3-(tert-butyl)-5-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 240 Mannosyl-oligosaccharide glucosidase 3.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276286 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276286&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302238 378157956 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167280 CCOc1ccc(Cl)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H33ClN2O3/c1-4-32-20-6-8-23(28)22(14-20)18-5-7-21-19(13-18)15-27(2,3)25(21)29-26(31)33-24-16-30-11-9-17(24)10-12-30/h5-8,13-14,17,24-25H,4,9-12,15-16H2,1-3H3,(H,29,31) KCJMEHLGTQUTBK-UHFFFAOYSA-N 276287 (S)-quinuclidin-3-yl (5-(2-chloro-5-ethoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 241 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276287 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276287&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309552 378157957 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167281 CC1(C)Cc2cc(-c3ccc(Cl)c(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28ClFN2O2/c1-25(2)13-18-11-16(17-4-6-20(26)21(27)12-17)3-5-19(18)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) KQNNPKGTZPRGSY-UHFFFAOYSA-N 276288 (S)-quinuclidin-3-yl (5-(4-chloro-3-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 242 Mannosyl-oligosaccharide glucosidase 5.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276288 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276288&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309551 378157958 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167282 Cc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1F InChI=1S/C26H31FN2O2/c1-16-5-4-6-20(23(16)27)18-7-8-21-19(13-18)14-26(2,3)24(21)28-25(30)31-22-15-29-11-9-17(22)10-12-29/h4-8,13,17,22,24H,9-12,14-15H2,1-3H3,(H,28,30) HJHBLQSTOWEDAJ-UHFFFAOYSA-N 276289 (S)-quinuclidin-3-yl (5-(2-fluoro-3-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 243 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276289 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276289&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309555 378157959 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167283 COc1ccc(C#N)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H31N3O3/c1-27(2)14-20-13-19(22-12-17(15-28)4-7-23(22)32-3)5-6-21(20)25(27)29-26(31)33-24-16-30-10-8-18(24)9-11-30/h4-7,12-13,18,24-25H,8-11,14,16H2,1-3H3,(H,29,31) WTWLGZZZNRTEGI-UHFFFAOYSA-N 276290 (S)-quinuclidin-3-yl (5-(5-cyano-2-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 244 Mannosyl-oligosaccharide glucosidase 1.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276290 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276290&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309553 378157960 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167284 CCOc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc(C(F)(F)F)c1 InChI=1S/C28H33F3N2O3/c1-4-35-22-13-19(12-21(14-22)28(29,30)31)18-5-6-23-20(11-18)15-27(2,3)25(23)32-26(34)36-24-16-33-9-7-17(24)8-10-33/h5-6,11-14,17,24-25H,4,7-10,15-16H2,1-3H3,(H,32,34) MLKHFARXUPLJCV-UHFFFAOYSA-N 276291 (S)-quinuclidin-3-yl (5-(3-ethoxy-5-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 245 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276291 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276291&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309554 378157961 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167285 CC1(C)Cc2cc(-c3cc(F)cc(C(F)(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28F4N2O2/c1-25(2)13-18-9-16(17-10-19(26(28,29)30)12-20(27)11-17)3-4-21(18)23(25)31-24(33)34-22-14-32-7-5-15(22)6-8-32/h3-4,9-12,15,22-23H,5-8,13-14H2,1-2H3,(H,31,33) KQQHPZWRTKPHDR-UHFFFAOYSA-N 276292 (S)-quinuclidin-3-yl (5-(3-fluoro-5-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 246 Mannosyl-oligosaccharide glucosidase 3.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276292 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276292&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309556 378157962 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167286 Cc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccc1OC(F)(F)F InChI=1S/C27H31F3N2O3/c1-16-12-18(5-7-22(16)35-27(28,29)30)19-4-6-21-20(13-19)14-26(2,3)24(21)31-25(33)34-23-15-32-10-8-17(23)9-11-32/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,31,33) KHPZRQGJCFJZSG-UHFFFAOYSA-N 276293 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(3-methyl-4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 247 Mannosyl-oligosaccharide glucosidase 11.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276293 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276293&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309557 378157963 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167287 CSc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc(C(F)(F)F)c1 InChI=1S/C27H31F3N2O2S/c1-26(2)14-19-10-17(18-11-20(27(28,29)30)13-21(12-18)35-3)4-5-22(19)24(26)31-25(33)34-23-15-32-8-6-16(23)7-9-32/h4-5,10-13,16,23-24H,6-9,14-15H2,1-3H3,(H,31,33) PLTYKTSOERZEEN-UHFFFAOYSA-N 276294 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(3-(methylthio)-5-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 248 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276294 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276294&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309558 378157964 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167288 CC1(C)Cc2cc(-c3ccc(OC(F)(F)F)c(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H28F4N2O3/c1-25(2)13-18-11-16(17-4-6-21(20(27)12-17)35-26(28,29)30)3-5-19(18)23(25)31-24(33)34-22-14-32-9-7-15(22)8-10-32/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,31,33) JWXPFXQMFWEIBI-UHFFFAOYSA-N 276295 (S)-quinuclidin-3-yl (5-(3-fluoro-4-(trifluoromethoxy)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 249 Mannosyl-oligosaccharide glucosidase 9.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276295 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276295&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309559 378157965 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167289 CCOc1cc(C(F)(F)F)ccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H33F3N2O3/c1-4-35-23-14-20(28(29,30)31)6-8-21(23)18-5-7-22-19(13-18)15-27(2,3)25(22)32-26(34)36-24-16-33-11-9-17(24)10-12-33/h5-8,13-14,17,24-25H,4,9-12,15-16H2,1-3H3,(H,32,34) JYPDRSPPSIGFKI-UHFFFAOYSA-N 276296 (S)-quinuclidin-3-yl (5-(2-ethoxy-4-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 250 Mannosyl-oligosaccharide glucosidase 4.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276296 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276296&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309560 378157966 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167290 COc1ccc(C(F)(F)F)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H31F3N2O3/c1-26(2)14-18-12-17(21-13-19(27(28,29)30)5-7-22(21)34-3)4-6-20(18)24(26)31-25(33)35-23-15-32-10-8-16(23)9-11-32/h4-7,12-13,16,23-24H,8-11,14-15H2,1-3H3,(H,31,33) JDIFHLRFBJVEMC-UHFFFAOYSA-N 276297 (S)-quinuclidin-3-yl (5-(2-methoxy-5-(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 251 Mannosyl-oligosaccharide glucosidase 1.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276297 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276297&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309562 378157967 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167291 CC1(C)Cc2cc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H28F6N2O2/c1-25(2)13-17-11-16(19-6-4-18(26(28,29)30)12-21(19)27(31,32)33)3-5-20(17)23(25)34-24(36)37-22-14-35-9-7-15(22)8-10-35/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,34,36) DKWZPMVTLHTMCM-UHFFFAOYSA-N 276298 (S)-quinuclidin-3-yl (5-(2,4-bis(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 252 Mannosyl-oligosaccharide glucosidase 7.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276298 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276298&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309563 378157968 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167292 Cc1c(Cl)cccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31ClN2O2/c1-16-20(5-4-6-22(16)27)18-7-8-21-19(13-18)14-26(2,3)24(21)28-25(30)31-23-15-29-11-9-17(23)10-12-29/h4-8,13,17,23-24H,9-12,14-15H2,1-3H3,(H,28,30) OEKKYJKRMYOIQP-UHFFFAOYSA-N 276299 (S)-quinuclidin-3-yl (5-(3-chloro-2-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 253 Mannosyl-oligosaccharide glucosidase 3.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276299 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276299&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309564 378157969 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167293 COc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccc1C InChI=1S/C27H34N2O3/c1-17-5-6-20(14-23(17)31-4)19-7-8-22-21(13-19)15-27(2,3)25(22)28-26(30)32-24-16-29-11-9-18(24)10-12-29/h5-8,13-14,18,24-25H,9-12,15-16H2,1-4H3,(H,28,30) BSRPUSADLXOIQH-UHFFFAOYSA-N 276300 (S)-quinuclidin-3-yl (5-(3-methoxy-4-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 254 Mannosyl-oligosaccharide glucosidase 7.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276300 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276300&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309565 378157970 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167294 Cc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccc1F InChI=1S/C26H31FN2O2/c1-16-12-18(5-7-22(16)27)19-4-6-21-20(13-19)14-26(2,3)24(21)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) IFRDBMIWCGGYQM-UHFFFAOYSA-N 276301 (S)-quinuclidin-3-yl (5-(4-fluoro-3-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 255 Mannosyl-oligosaccharide glucosidase 6.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276301 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276301&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309570 378157971 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167295 CCOc1ccc(F)cc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H33FN2O3/c1-4-32-23-8-6-20(28)14-22(23)18-5-7-21-19(13-18)15-27(2,3)25(21)29-26(31)33-24-16-30-11-9-17(24)10-12-30/h5-8,13-14,17,24-25H,4,9-12,15-16H2,1-3H3,(H,29,31) NYPRIMISKSUCDU-UHFFFAOYSA-N 276302 (S)-quinuclidin-3-yl (5-(2-ethoxy-5-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 256 Mannosyl-oligosaccharide glucosidase 1.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276302 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276302&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309566 378157972 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167296 CCCOc1cc(F)cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C28H35FN2O3/c1-4-11-33-23-14-20(13-22(29)15-23)19-5-6-24-21(12-19)16-28(2,3)26(24)30-27(32)34-25-17-31-9-7-18(25)8-10-31/h5-6,12-15,18,25-26H,4,7-11,16-17H2,1-3H3,(H,30,32) VOAIUIFDPGPXFE-UHFFFAOYSA-N 276303 (S)-quinuclidin-3-yl (5-(3-fluoro-5-propoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 257 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276303 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276303&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309567 378157973 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167297 CC1(C)Cc2cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H28F6N2O2/c1-25(2)13-18-9-16(17-10-19(26(28,29)30)12-20(11-17)27(31,32)33)3-4-21(18)23(25)34-24(36)37-22-14-35-7-5-15(22)6-8-35/h3-4,9-12,15,22-23H,5-8,13-14H2,1-2H3,(H,34,36) RLQTWJFTFIFIPR-UHFFFAOYSA-N 276304 (S)-quinuclidin-3-yl (5-(3,5-bis(trifluoromethyl)phenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 258 Mannosyl-oligosaccharide glucosidase 5.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276304 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276304&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309568 378157974 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167298 Cc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1Cl InChI=1S/C26H31ClN2O2/c1-16-4-5-19(13-22(16)27)18-6-7-21-20(12-18)14-26(2,3)24(21)28-25(30)31-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) WQCYRDOUIHZRLB-UHFFFAOYSA-N 276305 (S)-quinuclidin-3-yl (5-(3-chloro-4-methylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 259 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276305 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276305&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309569 378157975 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167299 Cc1ccc(C)c(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O2/c1-17-5-6-18(2)23(13-17)20-7-8-22-21(14-20)15-27(3,4)25(22)28-26(30)31-24-16-29-11-9-19(24)10-12-29/h5-8,13-14,19,24-25H,9-12,15-16H2,1-4H3,(H,28,30) LCTGLTUNKQJPFX-UHFFFAOYSA-N 276306 (S)-quinuclidin-3-yl (5-(2,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 260 Mannosyl-oligosaccharide glucosidase 1.000 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276306 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276306&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309571 378157976 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167300 CC1(C)Cc2cc(-c3ccc(F)c(Cl)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28ClFN2O2/c1-25(2)13-18-11-16(17-4-6-21(27)20(26)12-17)3-5-19(18)23(25)28-24(30)31-22-14-29-9-7-15(22)8-10-29/h3-6,11-12,15,22-23H,7-10,13-14H2,1-2H3,(H,28,30) MRIZLMKDLZQVBH-UHFFFAOYSA-N 276307 (S)-quinuclidin-3-yl (5-(3-chloro-4-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 261 Mannosyl-oligosaccharide glucosidase 3.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276307 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276307&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309572 378157977 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167301 CCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cn1 InChI=1S/C26H33N3O3/c1-4-31-23-8-6-19(15-27-23)18-5-7-21-20(13-18)14-26(2,3)24(21)28-25(30)32-22-16-29-11-9-17(22)10-12-29/h5-8,13,15,17,22,24H,4,9-12,14,16H2,1-3H3,(H,28,30) YCDHOIRDBJPDHV-UHFFFAOYSA-N 276308 (S)-quinuclidin-3-yl (5-(6-ethoxypyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 262 Mannosyl-oligosaccharide glucosidase 1.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276308 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276308&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309573 378157978 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167302 CCOc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccn1 InChI=1S/C26H33N3O3/c1-4-31-23-14-19(7-10-27-23)18-5-6-21-20(13-18)15-26(2,3)24(21)28-25(30)32-22-16-29-11-8-17(22)9-12-29/h5-7,10,13-14,17,22,24H,4,8-9,11-12,15-16H2,1-3H3,(H,28,30) PSJRLKIBFVPOGT-UHFFFAOYSA-N 276309 (S)-quinuclidin-3-yl (5-(2-ethoxypyridin-4-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 263 Mannosyl-oligosaccharide glucosidase 2.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276309 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276309&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309574 378157979 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167303 CC(C)Oc1cc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)ccn1 InChI=1S/C27H35N3O3/c1-17(2)32-24-14-20(7-10-28-24)19-5-6-22-21(13-19)15-27(3,4)25(22)29-26(31)33-23-16-30-11-8-18(23)9-12-30/h5-7,10,13-14,17-18,23,25H,8-9,11-12,15-16H2,1-4H3,(H,29,31) XDIZSLQKXOWCEO-UHFFFAOYSA-N 276310 (S)-quinuclidin-3-yl (5-(2-isopropoxypyridin-4-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 264 Mannosyl-oligosaccharide glucosidase 3.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276310 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276310&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309580 378157980 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167304 CCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cn1 InChI=1S/C27H35N3O3/c1-4-13-32-24-8-6-20(16-28-24)19-5-7-22-21(14-19)15-27(2,3)25(22)29-26(31)33-23-17-30-11-9-18(23)10-12-30/h5-8,14,16,18,23,25H,4,9-13,15,17H2,1-3H3,(H,29,31) YGVHKQUPYHOVQN-UHFFFAOYSA-N 276311 (S)-quinuclidin-3-yl (2,2-dimethyl-5-(6-propoxypyridin-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 265 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276311 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276311&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309575 378157981 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167305 CCCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cn1 InChI=1S/C28H37N3O3/c1-4-5-14-33-25-9-7-21(17-29-25)20-6-8-23-22(15-20)16-28(2,3)26(23)30-27(32)34-24-18-31-12-10-19(24)11-13-31/h6-9,15,17,19,24,26H,4-5,10-14,16,18H2,1-3H3,(H,30,32) ZTSKLDRZYHVONE-UHFFFAOYSA-N 276312 (S)-quinuclidin-3-yl (5-(6-butoxypyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 266 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276312 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276312&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309583 378157982 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167306 COCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cn1 InChI=1S/C27H35N3O4/c1-27(2)15-21-14-19(20-5-7-24(28-16-20)33-13-12-32-3)4-6-22(21)25(27)29-26(31)34-23-17-30-10-8-18(23)9-11-30/h4-7,14,16,18,23,25H,8-13,15,17H2,1-3H3,(H,29,31) LJQNHYZEMGZCSJ-UHFFFAOYSA-N 276313 (S)-quinuclidin-3-yl (5-(6-(2-methoxyethoxy)pyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 267 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276313 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276313&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309584 378157983 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167307 CC(C)COc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cn1 InChI=1S/C28H37N3O3/c1-18(2)17-33-25-8-6-21(15-29-25)20-5-7-23-22(13-20)14-28(3,4)26(23)30-27(32)34-24-16-31-11-9-19(24)10-12-31/h5-8,13,15,18-19,24,26H,9-12,14,16-17H2,1-4H3,(H,30,32) FEKWNCNKNNUVKE-UHFFFAOYSA-N 276314 (S)-quinuclidin-3-yl (5-(6-isobutoxypyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 268 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276314 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276314&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309578 378157984 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167308 CC(C)Cc1cccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C29H38N2O2/c1-19(2)14-20-6-5-7-22(15-20)23-8-9-25-24(16-23)17-29(3,4)27(25)30-28(32)33-26-18-31-12-10-21(26)11-13-31/h5-9,15-16,19,21,26-27H,10-14,17-18H2,1-4H3,(H,30,32) XONNJFBTVODVLS-UHFFFAOYSA-N 276315 (S)-quinuclidin-3-yl (5-(3-isobutylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 269 Mannosyl-oligosaccharide glucosidase 5.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276315 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276315&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309585 378157985 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167309 CCCCOc1ccc(-c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H38N2O3/c1-4-5-16-33-24-9-6-20(7-10-24)22-8-11-25-23(17-22)18-29(2,3)27(25)30-28(32)34-26-19-31-14-12-21(26)13-15-31/h6-11,17,21,26-27H,4-5,12-16,18-19H2,1-3H3,(H,30,32) DRLIIURGVYYCQH-UHFFFAOYSA-N 276316 (S)-quinuclidin-3-yl (5-(4-butoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 270 Mannosyl-oligosaccharide glucosidase 1.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276316 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276316&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309576 378157986 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167310 COc1ccnc(OC)c1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H33N3O4/c1-26(2)14-18-13-17(22-20(31-3)7-10-27-24(22)32-4)5-6-19(18)23(26)28-25(30)33-21-15-29-11-8-16(21)9-12-29/h5-7,10,13,16,21,23H,8-9,11-12,14-15H2,1-4H3,(H,28,30) CKIXZOOQNYIIIF-UHFFFAOYSA-N 276317 (S)-quinuclidin-3-yl (5-(2,4-dimethoxypyridin-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 271 Mannosyl-oligosaccharide glucosidase 5.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276317 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276317&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309586 378157987 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167311 CC(=O)c1sccc1-c1ccc2c(c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H30N2O3S/c1-15(28)22-19(8-11-31-22)17-4-5-20-18(12-17)13-25(2,3)23(20)26-24(29)30-21-14-27-9-6-16(21)7-10-27/h4-5,8,11-12,16,21,23H,6-7,9-10,13-14H2,1-3H3,(H,26,29) ZISXFLVXHZHILP-UHFFFAOYSA-N 276318 (S)-quinuclidin-3-yl (5-(2-acetylthiophen-3-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 272 Mannosyl-oligosaccharide glucosidase 9.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276318 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276318&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309577 378157988 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167312 CC1(C)Cc2cc(/C=C/c3cccc(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H31FN2O2/c1-27(2)16-21-14-19(7-6-18-4-3-5-22(28)15-18)8-9-23(21)25(27)29-26(31)32-24-17-30-12-10-20(24)11-13-30/h3-9,14-15,20,24-25H,10-13,16-17H2,1-2H3,(H,29,31) GLECQJCPSXHWPB-UHFFFAOYSA-N 276319 (S)-quinuclidin-3-yl (5-((E)-3-fluorostyryl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 273 Mannosyl-oligosaccharide glucosidase 5.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276319 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276319&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309579 378157989 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167313 CCc1ccc(/C=C/c2ccc3c(c2)CC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H36N2O2/c1-4-20-5-7-21(8-6-20)9-10-22-11-12-25-24(17-22)18-29(2,3)27(25)30-28(32)33-26-19-31-15-13-23(26)14-16-31/h5-12,17,23,26-27H,4,13-16,18-19H2,1-3H3,(H,30,32) IDQIEHRNDQIGKK-UHFFFAOYSA-N 276320 (S)-quinuclidin-3-yl (5-((E)-4-ethylstyryl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 274 Mannosyl-oligosaccharide glucosidase 2.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276320 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276320&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309581 378157990 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167314 CC1(C)Cc2cc(/C=C/C3CCCCC3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H38N2O2/c1-27(2)17-22-16-20(9-8-19-6-4-3-5-7-19)10-11-23(22)25(27)28-26(30)31-24-18-29-14-12-21(24)13-15-29/h8-11,16,19,21,24-25H,3-7,12-15,17-18H2,1-2H3,(H,28,30) VIZHYOXENAYBJI-UHFFFAOYSA-N 276321 (S)-quinuclidin-3-yl (5-((E)-2-cyclohexylvinyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 275 Mannosyl-oligosaccharide glucosidase 5.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276321 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276321&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309582 378157991 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167315 CCC1(CC)Cc2cc(-c3ccc(F)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H33FN2O2/c1-3-27(4-2)16-21-15-20(18-5-8-22(28)9-6-18)7-10-23(21)25(27)29-26(31)32-24-17-30-13-11-19(24)12-14-30/h5-10,15,19,24-25H,3-4,11-14,16-17H2,1-2H3,(H,29,31) UFPCAJXLIMKEBC-UHFFFAOYSA-N 276322 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 276 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276322 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276322&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309590 378157992 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167316 CCc1ccc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H38N2O2/c1-4-20-7-9-21(10-8-20)23-11-12-25-24(17-23)18-29(5-2,6-3)27(25)30-28(32)33-26-19-31-15-13-22(26)14-16-31/h7-12,17,22,26-27H,4-6,13-16,18-19H2,1-3H3,(H,30,32) IKEPOVMSSXDYKT-UHFFFAOYSA-N 276323 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-ethylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 277 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276323 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276323&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302288 378157993 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167317 CCCc1ccc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C30H40N2O2/c1-4-7-21-8-10-22(11-9-21)24-12-13-26-25(18-24)19-30(5-2,6-3)28(26)31-29(33)34-27-20-32-16-14-23(27)15-17-32/h8-13,18,23,27-28H,4-7,14-17,19-20H2,1-3H3,(H,31,33) QYAQZJKVYYWGGL-UHFFFAOYSA-N 276324 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-propylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 278 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276324 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276324&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309593 378157994 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167318 CCC1(CC)Cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C31H42N2O2/c1-6-31(7-2)19-24-18-23(21-8-11-25(12-9-21)30(3,4)5)10-13-26(24)28(31)32-29(34)35-27-20-33-16-14-22(27)15-17-33/h8-13,18,22,27-28H,6-7,14-17,19-20H2,1-5H3,(H,32,34) NPVGMJCBIQPGFQ-UHFFFAOYSA-N 276325 (S)-quinuclidin-3-yl (5-(4-(tert-butyl)phenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 279 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276325 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276325&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302343 378157995 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167319 CCCCc1ccc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C31H42N2O2/c1-4-7-8-22-9-11-23(12-10-22)25-13-14-27-26(19-25)20-31(5-2,6-3)29(27)32-30(34)35-28-21-33-17-15-24(28)16-18-33/h9-14,19,24,28-29H,4-8,15-18,20-21H2,1-3H3,(H,32,34) PBSGIOQVNXTGAU-UHFFFAOYSA-N 276326 (S)-quinuclidin-3-yl (5-(4-butylphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 280 Mannosyl-oligosaccharide glucosidase 0.400 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276326 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276326&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309591 378157996 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167320 CCC1(CC)Cc2cc(-c3ccc(C4CC4)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H38N2O2/c1-3-30(4-2)18-25-17-24(22-9-7-21(8-10-22)20-5-6-20)11-12-26(25)28(30)31-29(33)34-27-19-32-15-13-23(27)14-16-32/h7-12,17,20,23,27-28H,3-6,13-16,18-19H2,1-2H3,(H,31,33) LIPANDNMULHPDS-UHFFFAOYSA-N 276327 (S)-quinuclidin-3-yl (5-(4-cyclopropylphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 281 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276327 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276327&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302443 378157997 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167321 CCC1(CC)Cc2cc(-c3ccc(C(C)C)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O2/c1-5-30(6-2)18-25-17-24(22-9-7-21(8-10-22)20(3)4)11-12-26(25)28(30)31-29(33)34-27-19-32-15-13-23(27)14-16-32/h7-12,17,20,23,27-28H,5-6,13-16,18-19H2,1-4H3,(H,31,33) SGXJVYGYILNTRT-UHFFFAOYSA-N 276328 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-isopropylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 282 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276328 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276328&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309587 378157998 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167322 CCC1(CC)Cc2cc(-c3ccc(OC)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H36N2O3/c1-4-28(5-2)17-22-16-21(19-6-9-23(32-3)10-7-19)8-11-24(22)26(28)29-27(31)33-25-18-30-14-12-20(25)13-15-30/h6-11,16,20,25-26H,4-5,12-15,17-18H2,1-3H3,(H,29,31) VREDUMGRTHRHJN-UHFFFAOYSA-N 276329 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-methoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 283 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276329 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276329&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309594 378157999 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167323 CCOc1ccc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C29H38N2O3/c1-4-29(5-2)18-23-17-22(20-7-10-24(11-8-20)33-6-3)9-12-25(23)27(29)30-28(32)34-26-19-31-15-13-21(26)14-16-31/h7-12,17,21,26-27H,4-6,13-16,18-19H2,1-3H3,(H,30,32) OZCKQZLYUNNFBV-UHFFFAOYSA-N 276330 (S)-quinuclidin-3-yl (5-(4-ethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 284 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276330&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309588 378158000 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167324 CCCOc1ccc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C30H40N2O3/c1-4-17-34-25-10-7-21(8-11-25)23-9-12-26-24(18-23)19-30(5-2,6-3)28(26)31-29(33)35-27-20-32-15-13-22(27)14-16-32/h7-12,18,22,27-28H,4-6,13-17,19-20H2,1-3H3,(H,31,33) COKUQBRKXXMTLH-UHFFFAOYSA-N 276331 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-propoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 285 Mannosyl-oligosaccharide glucosidase 0.500 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276331 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276331&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309589 378158001 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167325 CCC1(CC)Cc2cc(-c3ccc(OC(C)C)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O3/c1-5-30(6-2)18-24-17-23(21-7-10-25(11-8-21)34-20(3)4)9-12-26(24)28(30)31-29(33)35-27-19-32-15-13-22(27)14-16-32/h7-12,17,20,22,27-28H,5-6,13-16,18-19H2,1-4H3,(H,31,33) LNEOQBUVVQZUHF-UHFFFAOYSA-N 276332 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-isopropoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 286 Mannosyl-oligosaccharide glucosidase 0.400 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276332 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276332&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309596 378158002 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167326 CCC1(CC)Cc2cc(-c3ccc(CC(C)C)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C31H42N2O2/c1-5-31(6-2)19-26-18-25(23-9-7-22(8-10-23)17-21(3)4)11-12-27(26)29(31)32-30(34)35-28-20-33-15-13-24(28)14-16-33/h7-12,18,21,24,28-29H,5-6,13-17,19-20H2,1-4H3,(H,32,34) XCIIKCKKBPLGQC-UHFFFAOYSA-N 276333 (S)-quinuclidin-3-yl (2,2-diethyl-5-(4-isobutylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 287 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276333 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276333&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309592 378158003 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167327 CCC1(CC)Cc2cc(-c3cccc(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C27H33FN2O2/c1-3-27(4-2)16-21-14-20(19-6-5-7-22(28)15-19)8-9-23(21)25(27)29-26(31)32-24-17-30-12-10-18(24)11-13-30/h5-9,14-15,18,24-25H,3-4,10-13,16-17H2,1-2H3,(H,29,31) AXIFOMDLYYENBW-UHFFFAOYSA-N 276334 (S)-quinuclidin-3-yl (2,2-diethyl-5-(3-fluorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 288 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276334 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276334&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309595 378158004 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167328 CCC1(CC)Cc2cc(-c3cccc(OC)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H36N2O3/c1-4-28(5-2)17-22-15-21(20-7-6-8-23(16-20)32-3)9-10-24(22)26(28)29-27(31)33-25-18-30-13-11-19(25)12-14-30/h6-10,15-16,19,25-26H,4-5,11-14,17-18H2,1-3H3,(H,29,31) SVKGSMPCCGXEPW-UHFFFAOYSA-N 276335 (S)-quinuclidin-3-yl (2,2-diethyl-5-(3-methoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 289 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276335 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276335&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309598 378158005 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167329 CCOc1cccc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C29H38N2O3/c1-4-29(5-2)18-23-16-22(21-8-7-9-24(17-21)33-6-3)10-11-25(23)27(29)30-28(32)34-26-19-31-14-12-20(26)13-15-31/h7-11,16-17,20,26-27H,4-6,12-15,18-19H2,1-3H3,(H,30,32) GAHBHFRAAFAQFN-UHFFFAOYSA-N 276336 (S)-quinuclidin-3-yl (5-(3-ethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 290 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276336 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276336&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309597 378158006 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167330 CCC1(CC)Cc2cc(-c3cccc(OC(C)C)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O3/c1-5-30(6-2)18-24-16-23(22-8-7-9-25(17-22)34-20(3)4)10-11-26(24)28(30)31-29(33)35-27-19-32-14-12-21(27)13-15-32/h7-11,16-17,20-21,27-28H,5-6,12-15,18-19H2,1-4H3,(H,31,33) USFGQTWVYSIEHE-UHFFFAOYSA-N 276337 (S)-quinuclidin-3-yl (2,2-diethyl-5-(3-isopropoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 291 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276337 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276337&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309599 378158007 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167331 CCc1cccc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C29H38N2O2/c1-4-20-8-7-9-22(16-20)23-10-11-25-24(17-23)18-29(5-2,6-3)27(25)30-28(32)33-26-19-31-14-12-21(26)13-15-31/h7-11,16-17,21,26-27H,4-6,12-15,18-19H2,1-3H3,(H,30,32) GVAKOPRERNKGAL-UHFFFAOYSA-N 276338 (S)-quinuclidin-3-yl (2,2-diethyl-5-(3-ethylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 292 Mannosyl-oligosaccharide glucosidase 1.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276338 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276338&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309600 378158008 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167332 CCC1(CC)Cc2cc(-c3cccc(C(C)C)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O2/c1-5-30(6-2)18-25-17-24(23-9-7-8-22(16-23)20(3)4)10-11-26(25)28(30)31-29(33)34-27-19-32-14-12-21(27)13-15-32/h7-11,16-17,20-21,27-28H,5-6,12-15,18-19H2,1-4H3,(H,31,33) XLQRPBJYTKLPCW-UHFFFAOYSA-N 276339 (S)-quinuclidin-3-yl (2,2-diethyl-5-(3-isopropylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 293 Mannosyl-oligosaccharide glucosidase 2.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276339 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276339&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309601 378158009 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167333 CCC1(CC)Cc2cc(-c3cccc(C(C)(C)C)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C31H42N2O2/c1-6-31(7-2)19-24-17-23(22-9-8-10-25(18-22)30(3,4)5)11-12-26(24)28(31)32-29(34)35-27-20-33-15-13-21(27)14-16-33/h8-12,17-18,21,27-28H,6-7,13-16,19-20H2,1-5H3,(H,32,34) SMIPZGLMIXQBLV-UHFFFAOYSA-N 276340 (S)-quinuclidin-3-yl (5-(3-(tert-butyl)phenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 294 Mannosyl-oligosaccharide glucosidase 4.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276340 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276340&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309602 378158010 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167334 CCC1(CC)Cc2cc(-c3cccc(OC)c3OC)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-5-29(6-2)17-21-16-20(22-8-7-9-24(33-3)26(22)34-4)10-11-23(21)27(29)30-28(32)35-25-18-31-14-12-19(25)13-15-31/h7-11,16,19,25,27H,5-6,12-15,17-18H2,1-4H3,(H,30,32) PIXWQCLRXZWDRB-UHFFFAOYSA-N 276341 (S)-quinuclidin-3-yl (5-(2,3-dimethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 295 Mannosyl-oligosaccharide glucosidase 2.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276341 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276341&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309603 378158011 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167335 CCC1(CC)Cc2cc(-c3ccc(OC)cc3OC)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-5-29(6-2)17-21-15-20(23-10-8-22(33-3)16-25(23)34-4)7-9-24(21)27(29)30-28(32)35-26-18-31-13-11-19(26)12-14-31/h7-10,15-16,19,26-27H,5-6,11-14,17-18H2,1-4H3,(H,30,32) AIUJJCNFTWKTJV-UHFFFAOYSA-N 276342 (S)-quinuclidin-3-yl (5-(2,4-dimethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 296 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276342 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276342&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309604 378158012 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167336 CCC1(CC)Cc2cc(-c3cc(OC)ccc3OC)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-5-29(6-2)17-21-15-20(24-16-22(33-3)8-10-25(24)34-4)7-9-23(21)27(29)30-28(32)35-26-18-31-13-11-19(26)12-14-31/h7-10,15-16,19,26-27H,5-6,11-14,17-18H2,1-4H3,(H,30,32) WHUYXPMOFLCDFB-UHFFFAOYSA-N 276343 (S)-quinuclidin-3-yl (5-(2,5-dimethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 297 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276343 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276343&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309605 378158013 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167337 CCC1(CC)Cc2cc(-c3ccc(OC)c(OC)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-5-29(6-2)17-22-15-20(21-8-10-24(33-3)25(16-21)34-4)7-9-23(22)27(29)30-28(32)35-26-18-31-13-11-19(26)12-14-31/h7-10,15-16,19,26-27H,5-6,11-14,17-18H2,1-4H3,(H,30,32) GUVWQVXBZXPHJK-UHFFFAOYSA-N 276344 (S)-quinuclidin-3-yl (5-(3,4-dimethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 298 Mannosyl-oligosaccharide glucosidase 6.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276344 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276344&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309608 378158014 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167338 CCC1(CC)Cc2cc(-c3cc(OC)cc(OC)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-5-29(6-2)17-22-13-20(21-14-23(33-3)16-24(15-21)34-4)7-8-25(22)27(29)30-28(32)35-26-18-31-11-9-19(26)10-12-31/h7-8,13-16,19,26-27H,5-6,9-12,17-18H2,1-4H3,(H,30,32) MHIFPUDSODJCGW-UHFFFAOYSA-N 276345 (S)-quinuclidin-3-yl (5-(3,5-dimethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 299 Mannosyl-oligosaccharide glucosidase 2.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276345 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276345&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309606 378158015 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167339 CCC1(CC)Cc2cc(-c3c(OC)cccc3OC)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-5-29(6-2)17-21-16-20(26-23(33-3)8-7-9-24(26)34-4)10-11-22(21)27(29)30-28(32)35-25-18-31-14-12-19(25)13-15-31/h7-11,16,19,25,27H,5-6,12-15,17-18H2,1-4H3,(H,30,32) MYYURAWOHKCTPI-UHFFFAOYSA-N 276346 (S)-quinuclidin-3-yl (5-(2,6-dimethoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 300 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276346 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276346&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309607 378158016 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167340 CCC1(CC)Cc2cc(-c3cccc(C(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H34F2N2O2/c1-3-28(4-2)16-22-15-20(19-6-5-7-21(14-19)26(29)30)8-9-23(22)25(28)31-27(33)34-24-17-32-12-10-18(24)11-13-32/h5-9,14-15,18,24-26H,3-4,10-13,16-17H2,1-2H3,(H,31,33) YOGGTTWEUOVQBC-UHFFFAOYSA-N 276347 (S)-quinuclidin-3-yl (5-(3-(difluoromethyl)phenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 301 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276347 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276347&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309609 378158017 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167341 CCC1(CC)Cc2cc(-c3cccc(N(C)C)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H39N3O2/c1-5-29(6-2)18-23-16-22(21-8-7-9-24(17-21)31(3)4)10-11-25(23)27(29)30-28(33)34-26-19-32-14-12-20(26)13-15-32/h7-11,16-17,20,26-27H,5-6,12-15,18-19H2,1-4H3,(H,30,33) WABNZGFJTMNQON-UHFFFAOYSA-N 276348 (S)-quinuclidin-3-yl (5-(3-(dimethylamino)phenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 302 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276348 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276348&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309610 378158018 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167342 CCOc1c(C)cc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C InChI=1S/C31H42N2O3/c1-6-31(7-2)18-25-17-23(24-15-20(4)28(35-8-3)21(5)16-24)9-10-26(25)29(31)32-30(34)36-27-19-33-13-11-22(27)12-14-33/h9-10,15-17,22,27,29H,6-8,11-14,18-19H2,1-5H3,(H,32,34) JZJDDQUVMBLQJO-UHFFFAOYSA-N 276349 (S)-quinuclidin-3-yl (5-(4-ethoxy-3,5-dimethylphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 303 Mannosyl-oligosaccharide glucosidase 4.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276349 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276349&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309611 378158019 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167343 CCCOc1c(C)cc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C InChI=1S/C32H44N2O3/c1-6-15-36-29-21(4)16-25(17-22(29)5)24-9-10-27-26(18-24)19-32(7-2,8-3)30(27)33-31(35)37-28-20-34-13-11-23(28)12-14-34/h9-10,16-18,23,28,30H,6-8,11-15,19-20H2,1-5H3,(H,33,35) UIRUTCYNPIBGBT-UHFFFAOYSA-N 276350 (S)-quinuclidin-3-yl (5-(3,5-dimethyl-4-propoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 304 Mannosyl-oligosaccharide glucosidase 3.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276350 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276350&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309615 378158020 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167344 CCCCOc1c(C)cc(-c2ccc3c(c2)CC(CC)(CC)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1C InChI=1S/C33H46N2O3/c1-6-9-16-37-30-22(4)17-26(18-23(30)5)25-10-11-28-27(19-25)20-33(7-2,8-3)31(28)34-32(36)38-29-21-35-14-12-24(29)13-15-35/h10-11,17-19,24,29,31H,6-9,12-16,20-21H2,1-5H3,(H,34,36) RMSGTQJPUCVZBO-UHFFFAOYSA-N 276351 (S)-quinuclidin-3-yl (5-(4-butoxy-3,5-dimethylphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 305 Mannosyl-oligosaccharide glucosidase 4.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276351&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309612 378158021 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167345 CCC1(CC)Cc2cc(-c3ccsc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H32N2O2S/c1-3-25(4-2)14-20-13-18(19-9-12-30-16-19)5-6-21(20)23(25)26-24(28)29-22-15-27-10-7-17(22)8-11-27/h5-6,9,12-13,16-17,22-23H,3-4,7-8,10-11,14-15H2,1-2H3,(H,26,28) IDLNRBAXGZYIQX-UHFFFAOYSA-N 276352 (S)-quinuclidin-3-yl (2,2-diethyl-5-(thiophen-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 306 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276352 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276352&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309613 378158022 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167346 CCC1(CC)Cc2cc(-c3ccoc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H32N2O3/c1-3-25(4-2)14-20-13-18(19-9-12-29-16-19)5-6-21(20)23(25)26-24(28)30-22-15-27-10-7-17(22)8-11-27/h5-6,9,12-13,16-17,22-23H,3-4,7-8,10-11,14-15H2,1-2H3,(H,26,28) DJADTLRKYMKVNF-UHFFFAOYSA-N 276353 (S)-quinuclidin-3-yl (2,2-diethyl-5-(furan-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 307 Mannosyl-oligosaccharide glucosidase 1.50 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276353 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276353&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309614 378158023 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167347 CCC1(CC)Cc2cc(-c3ccc(OCC4CC4)nc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H39N3O3/c1-3-30(4-2)16-24-15-22(23-8-10-27(31-17-23)35-19-20-5-6-20)7-9-25(24)28(30)32-29(34)36-26-18-33-13-11-21(26)12-14-33/h7-10,15,17,20-21,26,28H,3-6,11-14,16,18-19H2,1-2H3,(H,32,34) QIEZRZSRCCVHEQ-UHFFFAOYSA-N 276354 (S)-quinuclidin-3-yl (5-(6-(cyclopropylmethoxy)pyridin-3-yl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 308 Mannosyl-oligosaccharide glucosidase 0.300 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276354 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276354&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302432 378158024 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167348 CCC1(CC)Cc2cc(-c3ccc4c(c3)OC(F)(F)O4)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H32F2N2O4/c1-3-27(4-2)15-20-13-18(19-6-8-22-23(14-19)36-28(29,30)35-22)5-7-21(20)25(27)31-26(33)34-24-16-32-11-9-17(24)10-12-32/h5-8,13-14,17,24-25H,3-4,9-12,15-16H2,1-2H3,(H,31,33) QDGAQYDOVNCQPJ-UHFFFAOYSA-N 276355 (S)-quinuclidin-3-yl (5-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 309 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276355&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302436 378158025 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167349 CCC1(CC)Cc2cc(-c3ccc(OC)cc3F)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H35FN2O3/c1-4-28(5-2)16-20-14-19(22-9-7-21(33-3)15-24(22)29)6-8-23(20)26(28)30-27(32)34-25-17-31-12-10-18(25)11-13-31/h6-9,14-15,18,25-26H,4-5,10-13,16-17H2,1-3H3,(H,30,32) APRCLXJUZXRMLP-UHFFFAOYSA-N 276356 (S)-quinuclidin-3-yl (2,2-diethyl-5-(2-fluoro-4-methoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 310 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276356 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276356&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309620 378158026 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167350 CCC1(CC)Cc2cc(-c3ccc(OC(C)C)c(Cl)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H39ClN2O3/c1-5-30(6-2)17-23-15-21(22-8-10-26(25(31)16-22)35-19(3)4)7-9-24(23)28(30)32-29(34)36-27-18-33-13-11-20(27)12-14-33/h7-10,15-16,19-20,27-28H,5-6,11-14,17-18H2,1-4H3,(H,32,34) LKODZTLLQNTYGR-UHFFFAOYSA-N 276357 (S)-quinuclidin-3-yl (5-(3-chloro-4-isopropoxyphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 311 Mannosyl-oligosaccharide glucosidase 2.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276357 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276357&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309616 378158027 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167351 CCc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C28H36N2O3/c1-5-18-6-8-19(9-7-18)22-14-21-16-28(2,3)26(23(21)15-24(22)32-4)29-27(31)33-25-17-30-12-10-20(25)11-13-30/h6-9,14-15,20,25-26H,5,10-13,16-17H2,1-4H3,(H,29,31) ZRFJCSJPUBQHOI-UHFFFAOYSA-N 276358 (S)-quinuclidin-3-yl (5-(4-ethylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 312 Mannosyl-oligosaccharide glucosidase 2.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276358 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276358&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309621 378158028 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167352 CCCc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C29H38N2O3/c1-5-6-19-7-9-20(10-8-19)23-15-22-17-29(2,3)27(24(22)16-25(23)33-4)30-28(32)34-26-18-31-13-11-21(26)12-14-31/h7-10,15-16,21,26-27H,5-6,11-14,17-18H2,1-4H3,(H,30,32) AZQKNIWWTOKYOQ-UHFFFAOYSA-N 276359 (S)-quinuclidin-3-yl (6-methoxy-2,2-dimethyl-5-(4-propylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 313 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276359 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276359&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309617 378158029 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167353 COc1cc2c(cc1-c1ccc(C(C)C)cc1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O3/c1-18(2)19-6-8-20(9-7-19)23-14-22-16-29(3,4)27(24(22)15-25(23)33-5)30-28(32)34-26-17-31-12-10-21(26)11-13-31/h6-9,14-15,18,21,26-27H,10-13,16-17H2,1-5H3,(H,30,32) UJCBQDOSRZIEQQ-UHFFFAOYSA-N 276360 (S)-quinuclidin-3-yl (5-(4-isopropylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 314 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276360 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276360&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309618 378158030 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167354 COc1cc2c(cc1-c1ccc(CC(C)C)cc1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O3/c1-19(2)14-20-6-8-21(9-7-20)24-15-23-17-30(3,4)28(25(23)16-26(24)34-5)31-29(33)35-27-18-32-12-10-22(27)11-13-32/h6-9,15-16,19,22,27-28H,10-14,17-18H2,1-5H3,(H,31,33) LMZVZQPPMWHZGL-UHFFFAOYSA-N 276361 (S)-quinuclidin-3-yl (5-(4-isobutylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 315 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276361 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276361&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309619 378158031 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167355 COc1cc2c(cc1-c1ccc(C(C)(C)C)cc1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O3/c1-29(2,3)22-9-7-19(8-10-22)23-15-21-17-30(4,5)27(24(21)16-25(23)34-6)31-28(33)35-26-18-32-13-11-20(26)12-14-32/h7-10,15-16,20,26-27H,11-14,17-18H2,1-6H3,(H,31,33) VYMJEAFVGMBJNE-UHFFFAOYSA-N 276362 (S)-quinuclidin-3-yl (5-(4-(tert-butyl)phenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 316 Mannosyl-oligosaccharide glucosidase 1.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276362 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276362&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309622 378158032 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167356 COc1cc2c(cc1-c1ccc(C3CC3)cc1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H36N2O3/c1-29(2)16-22-14-23(20-8-6-19(7-9-20)18-4-5-18)25(33-3)15-24(22)27(29)30-28(32)34-26-17-31-12-10-21(26)11-13-31/h6-9,14-15,18,21,26-27H,4-5,10-13,16-17H2,1-3H3,(H,30,32) BYEQPMPVCNYIOT-UHFFFAOYSA-N 276363 (S)-quinuclidin-3-yl (5-(4-cyclopropylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 317 Mannosyl-oligosaccharide glucosidase 2.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276363 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276363&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309623 378158033 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167357 CCOc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C28H36N2O4/c1-5-33-21-8-6-18(7-9-21)22-14-20-16-28(2,3)26(23(20)15-24(22)32-4)29-27(31)34-25-17-30-12-10-19(25)11-13-30/h6-9,14-15,19,25-26H,5,10-13,16-17H2,1-4H3,(H,29,31) UPYWDLUAGCRGGT-UHFFFAOYSA-N 276364 (S)-quinuclidin-3-yl (5-(4-ethoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 318 Mannosyl-oligosaccharide glucosidase 2.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276364&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309624 378158034 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167358 CCCOc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C29H38N2O4/c1-5-14-34-22-8-6-19(7-9-22)23-15-21-17-29(2,3)27(24(21)16-25(23)33-4)30-28(32)35-26-18-31-12-10-20(26)11-13-31/h6-9,15-16,20,26-27H,5,10-14,17-18H2,1-4H3,(H,30,32) KWXDKVMGZOEQAF-UHFFFAOYSA-N 276365 (S)-quinuclidin-3-yl (6-methoxy-2,2-dimethyl-5-(4-propoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 319 Mannosyl-oligosaccharide glucosidase 1.000 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276365 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276365&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309627 378158035 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167359 COc1cc2c(cc1-c1ccc(OC(C)C)cc1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-18(2)34-22-8-6-19(7-9-22)23-14-21-16-29(3,4)27(24(21)15-25(23)33-5)30-28(32)35-26-17-31-12-10-20(26)11-13-31/h6-9,14-15,18,20,26-27H,10-13,16-17H2,1-5H3,(H,30,32) XZGHUBFQTUMMFM-UHFFFAOYSA-N 276366 (S)-quinuclidin-3-yl (5-(4-isopropoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 320 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276366 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276366&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309625 378158036 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167360 CCCOc1c(C)cc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1C InChI=1S/C31H42N2O4/c1-7-12-36-28-19(2)13-22(14-20(28)3)24-15-23-17-31(4,5)29(25(23)16-26(24)35-6)32-30(34)37-27-18-33-10-8-21(27)9-11-33/h13-16,21,27,29H,7-12,17-18H2,1-6H3,(H,32,34) FVPAPHMKNJYWAD-UHFFFAOYSA-N 276367 (S)-quinuclidin-3-yl (5-(3,5-dimethyl-4-propoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 321 Mannosyl-oligosaccharide glucosidase 4.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276367 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276367&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309626 378158037 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167361 COc1cc2c(cc1-c1ccc(OC(C)C)c(Cl)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H37ClN2O4/c1-17(2)35-24-7-6-19(13-23(24)30)21-12-20-15-29(3,4)27(22(20)14-25(21)34-5)31-28(33)36-26-16-32-10-8-18(26)9-11-32/h6-7,12-14,17-18,26-27H,8-11,15-16H2,1-5H3,(H,31,33) DIYAIOKGIFUTKJ-UHFFFAOYSA-N 276368 (S)-quinuclidin-3-yl (5-(3-chloro-4-isopropoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 322 Mannosyl-oligosaccharide glucosidase 4.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276368 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276368&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309628 378158038 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167362 COc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c(F)c1 InChI=1S/C27H33FN2O4/c1-27(2)14-17-11-21(19-6-5-18(32-3)12-22(19)28)23(33-4)13-20(17)25(27)29-26(31)34-24-15-30-9-7-16(24)8-10-30/h5-6,11-13,16,24-25H,7-10,14-15H2,1-4H3,(H,29,31) CTDFCSKEBRZOIU-UHFFFAOYSA-N 276369 (S)-quinuclidin-3-yl (5-(2-fluoro-4-methoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 323 Mannosyl-oligosaccharide glucosidase 5.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276369 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276369&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309632 378158039 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167363 CCCCOc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C30H40N2O4/c1-5-6-15-35-23-9-7-20(8-10-23)24-16-22-18-30(2,3)28(25(22)17-26(24)34-4)31-29(33)36-27-19-32-13-11-21(27)12-14-32/h7-10,16-17,21,27-28H,5-6,11-15,18-19H2,1-4H3,(H,31,33) HYIIZAJGOVKCFT-UHFFFAOYSA-N 276370 (S)-quinuclidin-3-yl (5-(4-butoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 324 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276370 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276370&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309629 378158040 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167364 COc1cc2c(cc1-c1ccc(CC(C)C)cc1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O3/c1-19(2)14-20-6-8-21(9-7-20)24-15-23-17-30(3,4)28(25(23)16-26(24)34-5)31-29(33)35-27-18-32-12-10-22(27)11-13-32/h6-9,15-16,19,22,27-28H,10-14,17-18H2,1-5H3,(H,31,33) LMZVZQPPMWHZGL-UHFFFAOYSA-N 276371 (S)-quinuclidin-3-yl (5-(4-isobutylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 325 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276371 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276371&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309630 378158041 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167365 COc1cc2c(cc1-c1ccc(OCC3CC3)nc1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H37N3O4/c1-29(2)14-21-12-22(20-6-7-26(30-15-20)35-17-18-4-5-18)24(34-3)13-23(21)27(29)31-28(33)36-25-16-32-10-8-19(25)9-11-32/h6-7,12-13,15,18-19,25,27H,4-5,8-11,14,16-17H2,1-3H3,(H,31,33) YWVIQFHHXXTXTO-UHFFFAOYSA-N 276372 (S)-quinuclidin-3-yl (5-(6-(cyclopropylmethoxy)pyridin-3-yl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 326 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276372 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276372&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309631 378158042 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167366 COc1ccc(Cl)cc1-c1cc2c(cc1OC)C(NC(=O)O[C@H]1CN3CCC1CC3)C(C)(C)C2 InChI=1S/C27H33ClN2O4/c1-27(2)14-17-11-20(21-12-18(28)5-6-22(21)32-3)23(33-4)13-19(17)25(27)29-26(31)34-24-15-30-9-7-16(24)8-10-30/h5-6,11-13,16,24-25H,7-10,14-15H2,1-4H3,(H,29,31) VKZCHSIPWRBHKT-UHFFFAOYSA-N 276373 (S)-quinuclidin-3-yl (5-(5-chloro-2-methoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 327 Mannosyl-oligosaccharide glucosidase 1.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276373 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276373&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309633 378158043 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167367 CCCCc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C30H40N2O3/c1-5-6-7-20-8-10-21(11-9-20)24-16-23-18-30(2,3)28(25(23)17-26(24)34-4)31-29(33)35-27-19-32-14-12-22(27)13-15-32/h8-11,16-17,22,27-28H,5-7,12-15,18-19H2,1-4H3,(H,31,33) UIEHXNSDJGYMQZ-UHFFFAOYSA-N 276374 (S)-quinuclidin-3-yl (5-(4-butylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 328 Mannosyl-oligosaccharide glucosidase 0.400 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276374 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276374&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309634 378158044 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167368 COc1cc2c(cc1-c1cc(C)c(OC)c(C)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-17-11-20(12-18(2)26(17)34-6)22-13-21-15-29(3,4)27(23(21)14-24(22)33-5)30-28(32)35-25-16-31-9-7-19(25)8-10-31/h11-14,19,25,27H,7-10,15-16H2,1-6H3,(H,30,32) HBLCRSHXUHIGQG-UHFFFAOYSA-N 276375 (S)-quinuclidin-3-yl (6-methoxy-5-(4-methoxy-3,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 329 Mannosyl-oligosaccharide glucosidase 4.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276375 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276375&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309635 378158045 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167369 CCOc1c(C)cc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1C InChI=1S/C30H40N2O4/c1-7-35-27-18(2)12-21(13-19(27)3)23-14-22-16-30(4,5)28(24(22)15-25(23)34-6)31-29(33)36-26-17-32-10-8-20(26)9-11-32/h12-15,20,26,28H,7-11,16-17H2,1-6H3,(H,31,33) IWEBGBNPZQKCGL-UHFFFAOYSA-N 276376 (S)-quinuclidin-3-yl (5-(4-ethoxy-3,5-dimethylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 330 Mannosyl-oligosaccharide glucosidase 5.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276376 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276376&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309636 378158046 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167370 CCCCOc1c(C)cc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1C InChI=1S/C32H44N2O4/c1-7-8-13-37-29-20(2)14-23(15-21(29)3)25-16-24-18-32(4,5)30(26(24)17-27(25)36-6)33-31(35)38-28-19-34-11-9-22(28)10-12-34/h14-17,22,28,30H,7-13,18-19H2,1-6H3,(H,33,35) FJLIIQVOAHPPNC-UHFFFAOYSA-N 276377 (S)-quinuclidin-3-yl (5-(4-butoxy-3,5-dimethylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 331 Mannosyl-oligosaccharide glucosidase 3.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276377 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276377&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309637 378158047 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167371 COc1cc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)ccn1 InChI=1S/C26H33N3O4/c1-26(2)14-18-11-19(17-5-8-27-23(12-17)32-4)21(31-3)13-20(18)24(26)28-25(30)33-22-15-29-9-6-16(22)7-10-29/h5,8,11-13,16,22,24H,6-7,9-10,14-15H2,1-4H3,(H,28,30) QZTDZRSDNISPBL-UHFFFAOYSA-N 276378 (S)-quinuclidin-3-yl (6-methoxy-5-(2-methoxypyridin-4-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 332 Mannosyl-oligosaccharide glucosidase 5.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276378 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276378&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309638 378158048 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167372 COc1cc2c(cc1-c1cccc(F)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C26H31FN2O3/c1-26(2)14-18-12-20(17-5-4-6-19(27)11-17)22(31-3)13-21(18)24(26)28-25(30)32-23-15-29-9-7-16(23)8-10-29/h4-6,11-13,16,23-24H,7-10,14-15H2,1-3H3,(H,28,30) NPYYQAQQAUGOOK-UHFFFAOYSA-N 276379 (S)-quinuclidin-3-yl (5-(3-fluorophenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 333 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276379 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276379&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309639 378158049 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167373 CCc1cccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C28H36N2O3/c1-5-18-7-6-8-20(13-18)22-14-21-16-28(2,3)26(23(21)15-24(22)32-4)29-27(31)33-25-17-30-11-9-19(25)10-12-30/h6-8,13-15,19,25-26H,5,9-12,16-17H2,1-4H3,(H,29,31) WIMIQVNWSIQJTK-UHFFFAOYSA-N 276380 (S)-quinuclidin-3-yl (5-(3-ethylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 334 Mannosyl-oligosaccharide glucosidase 0.100 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276380 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276380&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309640 378158050 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167374 COc1cc2c(cc1-c1cccc(CC(C)C)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O3/c1-19(2)13-20-7-6-8-22(14-20)24-15-23-17-30(3,4)28(25(23)16-26(24)34-5)31-29(33)35-27-18-32-11-9-21(27)10-12-32/h6-8,14-16,19,21,27-28H,9-13,17-18H2,1-5H3,(H,31,33) RTLWKBFEZZHIMM-UHFFFAOYSA-N 276381 (S)-quinuclidin-3-yl (5-(3-isobutylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 335 Mannosyl-oligosaccharide glucosidase 4.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276381 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276381&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302203 378158051 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167375 COc1cc2c(cc1-c1cccc(C(C)C)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O3/c1-18(2)20-7-6-8-21(13-20)23-14-22-16-29(3,4)27(24(22)15-25(23)33-5)30-28(32)34-26-17-31-11-9-19(26)10-12-31/h6-8,13-15,18-19,26-27H,9-12,16-17H2,1-5H3,(H,30,32) MXLMGJVVANSSPM-UHFFFAOYSA-N 276382 (S)-quinuclidin-3-yl (5-(3-isopropylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 336 Mannosyl-oligosaccharide glucosidase 4.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276382 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276382&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309641 378158052 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167376 COc1cc2c(cc1-c1cccc(C(C)(C)C)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O3/c1-29(2,3)22-9-7-8-20(14-22)23-15-21-17-30(4,5)27(24(21)16-25(23)34-6)31-28(33)35-26-18-32-12-10-19(26)11-13-32/h7-9,14-16,19,26-27H,10-13,17-18H2,1-6H3,(H,31,33) JMGXBAARFFKYQK-UHFFFAOYSA-N 276383 (S)-quinuclidin-3-yl (5-(3-(tert-butyl)phenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 337 Mannosyl-oligosaccharide glucosidase 8.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276383 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276383&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309642 378158053 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167377 COc1cccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C27H34N2O4/c1-27(2)15-19-13-21(18-6-5-7-20(12-18)31-3)23(32-4)14-22(19)25(27)28-26(30)33-24-16-29-10-8-17(24)9-11-29/h5-7,12-14,17,24-25H,8-11,15-16H2,1-4H3,(H,28,30) UUUUPMVQPOHYRD-UHFFFAOYSA-N 276384 (S)-quinuclidin-3-yl (6-methoxy-5-(3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 338 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276384 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276384&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309643 378158054 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167378 CCOc1cccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C28H36N2O4/c1-5-33-21-8-6-7-19(13-21)22-14-20-16-28(2,3)26(23(20)15-24(22)32-4)29-27(31)34-25-17-30-11-9-18(25)10-12-30/h6-8,13-15,18,25-26H,5,9-12,16-17H2,1-4H3,(H,29,31) KSXLDGKPGAHZPQ-UHFFFAOYSA-N 276385 (S)-quinuclidin-3-yl (5-(3-ethoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 339 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276385 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276385&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309644 378158055 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167379 CCCOc1cccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C29H38N2O4/c1-5-13-34-22-8-6-7-20(14-22)23-15-21-17-29(2,3)27(24(21)16-25(23)33-4)30-28(32)35-26-18-31-11-9-19(26)10-12-31/h6-8,14-16,19,26-27H,5,9-13,17-18H2,1-4H3,(H,30,32) AFNGRCWDNDHAKH-UHFFFAOYSA-N 276386 (S)-quinuclidin-3-yl (6-methoxy-2,2-dimethyl-5-(3-propoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 340 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276386 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276386&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309645 378158056 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167380 COc1cc2c(cc1-c1cccc(OC(C)C)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C29H38N2O4/c1-18(2)34-22-8-6-7-20(13-22)23-14-21-16-29(3,4)27(24(21)15-25(23)33-5)30-28(32)35-26-17-31-11-9-19(26)10-12-31/h6-8,13-15,18-19,26-27H,9-12,16-17H2,1-5H3,(H,30,32) LOQFPBCJFYAZOJ-UHFFFAOYSA-N 276387 (S)-quinuclidin-3-yl (5-(3-isopropoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 341 Mannosyl-oligosaccharide glucosidase 3.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276387 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276387&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309656 378158057 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167381 CCCCOc1cccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C30H40N2O4/c1-5-6-14-35-23-9-7-8-21(15-23)24-16-22-18-30(2,3)28(25(22)17-26(24)34-4)31-29(33)36-27-19-32-12-10-20(27)11-13-32/h7-9,15-17,20,27-28H,5-6,10-14,18-19H2,1-4H3,(H,31,33) IUKFQDLPUVACOQ-UHFFFAOYSA-N 276388 (S)-quinuclidin-3-yl (5-(3-butoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 342 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276388 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276388&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309646 378158058 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167382 COc1cc2c(cc1-c1cccc(OCC(C)C)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C30H40N2O4/c1-19(2)18-35-23-8-6-7-21(13-23)24-14-22-16-30(3,4)28(25(22)15-26(24)34-5)31-29(33)36-27-17-32-11-9-20(27)10-12-32/h6-8,13-15,19-20,27-28H,9-12,16-18H2,1-5H3,(H,31,33) ZEFMBORZKYVKGO-UHFFFAOYSA-N 276389 (S)-quinuclidin-3-yl (5-(3-isobutoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 343 Mannosyl-oligosaccharide glucosidase 2.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276389 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276389&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309648 378158059 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167383 COc1ccc(OC)c(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C28H36N2O5/c1-28(2)15-18-12-21(22-13-19(32-3)6-7-23(22)33-4)24(34-5)14-20(18)26(28)29-27(31)35-25-16-30-10-8-17(25)9-11-30/h6-7,12-14,17,25-26H,8-11,15-16H2,1-5H3,(H,29,31) UKUOUNNFXCLNIQ-UHFFFAOYSA-N 276390 (S)-quinuclidin-3-yl (5-(2,5-dimethoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 344 Mannosyl-oligosaccharide glucosidase 2.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276390 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276390&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309647 378158060 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167384 COc1cc(OC)cc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C28H36N2O5/c1-28(2)15-19-12-22(18-10-20(32-3)13-21(11-18)33-4)24(34-5)14-23(19)26(28)29-27(31)35-25-16-30-8-6-17(25)7-9-30/h10-14,17,25-26H,6-9,15-16H2,1-5H3,(H,29,31) AAJQJTJYUZNMQG-UHFFFAOYSA-N 276391 (S)-quinuclidin-3-yl (5-(3,5-dimethoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 345 Mannosyl-oligosaccharide glucosidase 3.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276391 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276391&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309649 378158061 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167385 COc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c(Cl)c1 InChI=1S/C27H33ClN2O4/c1-27(2)14-17-11-21(19-6-5-18(32-3)12-22(19)28)23(33-4)13-20(17)25(27)29-26(31)34-24-15-30-9-7-16(24)8-10-30/h5-6,11-13,16,24-25H,7-10,14-15H2,1-4H3,(H,29,31) YYJBRPKOTGMDHZ-UHFFFAOYSA-N 276392 (S)-quinuclidin-3-yl (5-(2-chloro-4-methoxyphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 346 Mannosyl-oligosaccharide glucosidase 2.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276392 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276392&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309650 378158062 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167386 CCOc1ccc(-c2cc3c(cc2OC)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1F InChI=1S/C28H35FN2O4/c1-5-34-23-7-6-18(13-22(23)29)20-12-19-15-28(2,3)26(21(19)14-24(20)33-4)30-27(32)35-25-16-31-10-8-17(25)9-11-31/h6-7,12-14,17,25-26H,5,8-11,15-16H2,1-4H3,(H,30,32) RHQPGEIBLICIPK-UHFFFAOYSA-N 276393 (S)-quinuclidin-3-yl (5-(4-ethoxy-3-fluorophenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 347 Mannosyl-oligosaccharide glucosidase 2.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276393 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276393&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309662 378158063 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167387 COc1cc2c(cc1-c1cc(C)c(OC(C)C)c(C)c1)CC(C)(C)C2NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C31H42N2O4/c1-18(2)36-28-19(3)12-22(13-20(28)4)24-14-23-16-31(5,6)29(25(23)15-26(24)35-7)32-30(34)37-27-17-33-10-8-21(27)9-11-33/h12-15,18,21,27,29H,8-11,16-17H2,1-7H3,(H,32,34) LQEVSTPVRDRRSC-UHFFFAOYSA-N 276394 (S)-quinuclidin-3-yl (5-(4-isopropoxy-3,5-dimethylphenyl)-6-methoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 348 Mannosyl-oligosaccharide glucosidase 6.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276394 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276394&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309668 378158064 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167388 CCc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C27H33FN2O2/c1-4-17-5-7-18(8-6-17)21-13-20-15-27(2,3)25(22(20)14-23(21)28)29-26(31)32-24-16-30-11-9-19(24)10-12-30/h5-8,13-14,19,24-25H,4,9-12,15-16H2,1-3H3,(H,29,31) PGFPEBNEMDTALM-UHFFFAOYSA-N 276395 (S)-quinuclidin-3-yl (5-(4-ethylphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 349 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276395 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276395&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309653 378158065 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167389 CCCc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C28H35FN2O2/c1-4-5-18-6-8-19(9-7-18)22-14-21-16-28(2,3)26(23(21)15-24(22)29)30-27(32)33-25-17-31-12-10-20(25)11-13-31/h6-9,14-15,20,25-26H,4-5,10-13,16-17H2,1-3H3,(H,30,32) BZTPSJVHPHOLCL-UHFFFAOYSA-N 276396 (S)-quinuclidin-3-yl (6-fluoro-2,2-dimethyl-5-(4-propylphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 350 Mannosyl-oligosaccharide glucosidase 0.400 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276396 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276396&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309663 378158066 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167390 CC(C)c1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C28H35FN2O2/c1-17(2)18-5-7-19(8-6-18)22-13-21-15-28(3,4)26(23(21)14-24(22)29)30-27(32)33-25-16-31-11-9-20(25)10-12-31/h5-8,13-14,17,20,25-26H,9-12,15-16H2,1-4H3,(H,30,32) XPHKIVUZAVGSHW-UHFFFAOYSA-N 276397 (S)-quinuclidin-3-yl (6-fluoro-5-(4-isopropylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 351 Mannosyl-oligosaccharide glucosidase 0.500 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276397 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276397&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309651 378158067 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167391 CC(C)Cc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C29H37FN2O2/c1-18(2)13-19-5-7-20(8-6-19)23-14-22-16-29(3,4)27(24(22)15-25(23)30)31-28(33)34-26-17-32-11-9-21(26)10-12-32/h5-8,14-15,18,21,26-27H,9-13,16-17H2,1-4H3,(H,31,33) XYQITLFNMIWFRF-UHFFFAOYSA-N 276398 (S)-quinuclidin-3-yl (6-fluoro-5-(4-isobutylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 352 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276398 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276398&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309658 378158068 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167392 CC(C)(C)c1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C29H37FN2O2/c1-28(2,3)21-8-6-18(7-9-21)22-14-20-16-29(4,5)26(23(20)15-24(22)30)31-27(33)34-25-17-32-12-10-19(25)11-13-32/h6-9,14-15,19,25-26H,10-13,16-17H2,1-5H3,(H,31,33) ZQCRIMUULRVIIS-UHFFFAOYSA-N 276399 (S)-quinuclidin-3-yl (5-(4-(tert-butyl)phenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 353 Mannosyl-oligosaccharide glucosidase 1.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276399 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276399&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309654 378158069 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167393 CC1(C)Cc2cc(-c3ccc(C4CC4)cc3)c(F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H33FN2O2/c1-28(2)15-21-13-22(19-7-5-18(6-8-19)17-3-4-17)24(29)14-23(21)26(28)30-27(32)33-25-16-31-11-9-20(25)10-12-31/h5-8,13-14,17,20,25-26H,3-4,9-12,15-16H2,1-2H3,(H,30,32) NPOIUVOGTUNWDK-UHFFFAOYSA-N 276400 (S)-quinuclidin-3-yl (5-(4-cyclopropylphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 354 Mannosyl-oligosaccharide glucosidase 0.300 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276400 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276400&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309652 378158070 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167394 COc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C26H31FN2O3/c1-26(2)14-18-12-20(16-4-6-19(31-3)7-5-16)22(27)13-21(18)24(26)28-25(30)32-23-15-29-10-8-17(23)9-11-29/h4-7,12-13,17,23-24H,8-11,14-15H2,1-3H3,(H,28,30) NUYXJVKVFKZGNM-UHFFFAOYSA-N 276401 (S)-quinuclidin-3-yl (6-fluoro-5-(4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 355 Mannosyl-oligosaccharide glucosidase 1.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276401 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276401&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309660 378158071 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167395 CCOc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C27H33FN2O3/c1-4-32-20-7-5-17(6-8-20)21-13-19-15-27(2,3)25(22(19)14-23(21)28)29-26(31)33-24-16-30-11-9-18(24)10-12-30/h5-8,13-14,18,24-25H,4,9-12,15-16H2,1-3H3,(H,29,31) BIJMJPXNPQGHRV-UHFFFAOYSA-N 276402 (S)-quinuclidin-3-yl (5-(4-ethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 356 Mannosyl-oligosaccharide glucosidase 0.500 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276402 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276402&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309655 378158072 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167396 CCCOc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C28H35FN2O3/c1-4-13-33-21-7-5-18(6-8-21)22-14-20-16-28(2,3)26(23(20)15-24(22)29)30-27(32)34-25-17-31-11-9-19(25)10-12-31/h5-8,14-15,19,25-26H,4,9-13,16-17H2,1-3H3,(H,30,32) LMQRNUURKLHHGE-UHFFFAOYSA-N 276403 (S)-quinuclidin-3-yl (6-fluoro-2,2-dimethyl-5-(4-propoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 357 Mannosyl-oligosaccharide glucosidase 0.300 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276403 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276403&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309657 378158073 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167397 CC(C)Oc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C28H35FN2O3/c1-17(2)33-21-7-5-18(6-8-21)22-13-20-15-28(3,4)26(23(20)14-24(22)29)30-27(32)34-25-16-31-11-9-19(25)10-12-31/h5-8,13-14,17,19,25-26H,9-12,15-16H2,1-4H3,(H,30,32) XYQYBJRRLCAHJB-UHFFFAOYSA-N 276404 (S)-quinuclidin-3-yl (6-fluoro-5-(4-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 358 Mannosyl-oligosaccharide glucosidase 0.300 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276404&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309659 378158074 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167398 CC(C)Oc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1Cl InChI=1S/C28H34ClFN2O3/c1-16(2)34-24-6-5-18(12-22(24)29)20-11-19-14-28(3,4)26(21(19)13-23(20)30)31-27(33)35-25-15-32-9-7-17(25)8-10-32/h5-6,11-13,16-17,25-26H,7-10,14-15H2,1-4H3,(H,31,33) OIJWQLOVBQAZBR-UHFFFAOYSA-N 276405 (S)-quinuclidin-3-yl (5-(3-chloro-4-isopropoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 359 Mannosyl-oligosaccharide glucosidase 2.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276405 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276405&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309661 378158075 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167399 COc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c(F)c1 InChI=1S/C26H30F2N2O3/c1-26(2)13-16-10-20(18-5-4-17(32-3)11-21(18)27)22(28)12-19(16)24(26)29-25(31)33-23-14-30-8-6-15(23)7-9-30/h4-5,10-12,15,23-24H,6-9,13-14H2,1-3H3,(H,29,31) VTBLRAWPMKIEGF-UHFFFAOYSA-N 276406 (S)-quinuclidin-3-yl (6-fluoro-5-(2-fluoro-4-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 360 Mannosyl-oligosaccharide glucosidase 0.700 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276406 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276406&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309666 378158076 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167400 CCCCOc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C29H37FN2O3/c1-4-5-14-34-22-8-6-19(7-9-22)23-15-21-17-29(2,3)27(24(21)16-25(23)30)31-28(33)35-26-18-32-12-10-20(26)11-13-32/h6-9,15-16,20,26-27H,4-5,10-14,17-18H2,1-3H3,(H,31,33) HWLFGHKBFFSXMS-UHFFFAOYSA-N 276407 (S)-quinuclidin-3-yl (5-(4-butoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 361 Mannosyl-oligosaccharide glucosidase 0.100 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276407 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276407&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309669 378158077 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167401 CC(C)COc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C29H37FN2O3/c1-18(2)17-34-22-7-5-19(6-8-22)23-13-21-15-29(3,4)27(24(21)14-25(23)30)31-28(33)35-26-16-32-11-9-20(26)10-12-32/h5-8,13-14,18,20,26-27H,9-12,15-17H2,1-4H3,(H,31,33) PPLBCQXHUKIWEW-UHFFFAOYSA-N 276408 (S)-quinuclidin-3-yl (6-fluoro-5-(4-isobutoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 362 Mannosyl-oligosaccharide glucosidase 0.200 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276408 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276408&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309665 378158078 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167402 CC1(C)Cc2cc(-c3ccc(OCC4CC4)nc3)c(F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C28H34FN3O3/c1-28(2)13-20-11-21(19-5-6-25(30-14-19)34-16-17-3-4-17)23(29)12-22(20)26(28)31-27(33)35-24-15-32-9-7-18(24)8-10-32/h5-6,11-12,14,17-18,24,26H,3-4,7-10,13,15-16H2,1-2H3,(H,31,33) BVGYNEUSVKZKAC-UHFFFAOYSA-N 276409 (S)-quinuclidin-3-yl (5-(6-(cyclopropylmethoxy)pyridin-3-yl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 363 Mannosyl-oligosaccharide glucosidase 0.100 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276409 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276409&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309664 378158079 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167403 COc1ccc(Cl)cc1-c1cc2c(cc1F)C(NC(=O)O[C@H]1CN3CCC1CC3)C(C)(C)C2 InChI=1S/C26H30ClFN2O3/c1-26(2)13-16-10-19(20-11-17(27)4-5-22(20)32-3)21(28)12-18(16)24(26)29-25(31)33-23-14-30-8-6-15(23)7-9-30/h4-5,10-12,15,23-24H,6-9,13-14H2,1-3H3,(H,29,31) YCDFACRTVWVSSN-UHFFFAOYSA-N 276410 (S)-quinuclidin-3-yl (5-(5-chloro-2-methoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 364 Mannosyl-oligosaccharide glucosidase 0.100 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276410 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276410&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309670 378158080 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167404 CCCCc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1 InChI=1S/C29H37FN2O2/c1-4-5-6-19-7-9-20(10-8-19)23-15-22-17-29(2,3)27(24(22)16-25(23)30)31-28(33)34-26-18-32-13-11-21(26)12-14-32/h7-10,15-16,21,26-27H,4-6,11-14,17-18H2,1-3H3,(H,31,33) NGSYJIQXNNORNW-UHFFFAOYSA-N 276411 (S)-quinuclidin-3-yl (5-(4-butylphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 365 Mannosyl-oligosaccharide glucosidase 0.300 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276411 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276411&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309667 378158081 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167405 COc1c(C)cc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1C InChI=1S/C28H35FN2O3/c1-16-10-19(11-17(2)25(16)33-5)21-12-20-14-28(3,4)26(22(20)13-23(21)29)30-27(32)34-24-15-31-8-6-18(24)7-9-31/h10-13,18,24,26H,6-9,14-15H2,1-5H3,(H,30,32) QGTMCJACBFQKOK-UHFFFAOYSA-N 276412 (S)-quinuclidin-3-yl (6-fluoro-5-(4-methoxy-3,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 366 Mannosyl-oligosaccharide glucosidase 5.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276412 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276412&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309671 378158082 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167406 CCOc1c(C)cc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1C InChI=1S/C29H37FN2O3/c1-6-34-26-17(2)11-20(12-18(26)3)22-13-21-15-29(4,5)27(23(21)14-24(22)30)31-28(33)35-25-16-32-9-7-19(25)8-10-32/h11-14,19,25,27H,6-10,15-16H2,1-5H3,(H,31,33) PLQMQVCIHMFYIB-UHFFFAOYSA-N 276413 (S)-quinuclidin-3-yl (5-(4-ethoxy-3,5-dimethylphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 367 Mannosyl-oligosaccharide glucosidase 4.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276413 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276413&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309672 378158083 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167407 CCCCOc1c(C)cc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1C InChI=1S/C31H41FN2O3/c1-6-7-12-36-28-19(2)13-22(14-20(28)3)24-15-23-17-31(4,5)29(25(23)16-26(24)32)33-30(35)37-27-18-34-10-8-21(27)9-11-34/h13-16,21,27,29H,6-12,17-18H2,1-5H3,(H,33,35) UZHSSNLEWQNRJE-UHFFFAOYSA-N 276414 (S)-quinuclidin-3-yl (5-(4-butoxy-3,5-dimethylphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 368 Mannosyl-oligosaccharide glucosidase 6.20 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276414 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276414&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309673 378158084 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167408 COc1cc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)ccn1 InChI=1S/C25H30FN3O3/c1-25(2)13-17-10-18(16-4-7-27-22(11-16)31-3)20(26)12-19(17)23(25)28-24(30)32-21-14-29-8-5-15(21)6-9-29/h4,7,10-12,15,21,23H,5-6,8-9,13-14H2,1-3H3,(H,28,30) ZGDLSCQDAIMWMS-UHFFFAOYSA-N 276415 (S)-quinuclidin-3-yl (6-fluoro-5-(2-methoxypyridin-4-yl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 369 Mannosyl-oligosaccharide glucosidase 2.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276415 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276415&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302309 378158085 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167409 CC1(C)Cc2cc(-c3cccc(F)c3)c(F)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H28F2N2O2/c1-25(2)13-17-11-19(16-4-3-5-18(26)10-16)21(27)12-20(17)23(25)28-24(30)31-22-14-29-8-6-15(22)7-9-29/h3-5,10-12,15,22-23H,6-9,13-14H2,1-2H3,(H,28,30) OESCFLRGQUJBAO-UHFFFAOYSA-N 276416 (S)-quinuclidin-3-yl (6-fluoro-5-(3-fluorophenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 370 Mannosyl-oligosaccharide glucosidase 1.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276416 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276416&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302295 378158086 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167410 CCc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C27H33FN2O2/c1-4-17-6-5-7-19(12-17)21-13-20-15-27(2,3)25(22(20)14-23(21)28)29-26(31)32-24-16-30-10-8-18(24)9-11-30/h5-7,12-14,18,24-25H,4,8-11,15-16H2,1-3H3,(H,29,31) ZUPXQPDBRXVEPV-UHFFFAOYSA-N 276417 (S)-quinuclidin-3-yl (5-(3-ethylphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 371 Mannosyl-oligosaccharide glucosidase 2.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276417 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276417&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302289 378158087 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167411 CC(C)Cc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C29H37FN2O2/c1-18(2)12-19-6-5-7-21(13-19)23-14-22-16-29(3,4)27(24(22)15-25(23)30)31-28(33)34-26-17-32-10-8-20(26)9-11-32/h5-7,13-15,18,20,26-27H,8-12,16-17H2,1-4H3,(H,31,33) TYPYAPJMDCHORG-UHFFFAOYSA-N 276418 (S)-quinuclidin-3-yl (6-fluoro-5-(3-isobutylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 372 Mannosyl-oligosaccharide glucosidase 3.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276418 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276418&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302271 378158088 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167412 CC(C)c1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C28H35FN2O2/c1-17(2)19-6-5-7-20(12-19)22-13-21-15-28(3,4)26(23(21)14-24(22)29)30-27(32)33-25-16-31-10-8-18(25)9-11-31/h5-7,12-14,17-18,25-26H,8-11,15-16H2,1-4H3,(H,30,32) VBJZNNADLQDEPC-UHFFFAOYSA-N 276419 (S)-quinuclidin-3-yl (6-fluoro-5-(3-isopropylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 373 Mannosyl-oligosaccharide glucosidase 3.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276419 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276419&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302224 378158089 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167413 CC(C)(C)c1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C29H37FN2O2/c1-28(2,3)21-8-6-7-19(13-21)22-14-20-16-29(4,5)26(23(20)15-24(22)30)31-27(33)34-25-17-32-11-9-18(25)10-12-32/h6-8,13-15,18,25-26H,9-12,16-17H2,1-5H3,(H,31,33) WWKDXDHNMVDRAD-UHFFFAOYSA-N 276420 (S)-quinuclidin-3-yl (5-(3-(tert-butyl)phenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 374 Mannosyl-oligosaccharide glucosidase 7.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276420 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276420&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302274 378158090 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167414 COc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C26H31FN2O3/c1-26(2)14-18-12-20(17-5-4-6-19(11-17)31-3)22(27)13-21(18)24(26)28-25(30)32-23-15-29-9-7-16(23)8-10-29/h4-6,11-13,16,23-24H,7-10,14-15H2,1-3H3,(H,28,30) KPYVWRSTOGUSJP-UHFFFAOYSA-N 276421 (S)-quinuclidin-3-yl (6-fluoro-5-(3-methoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 375 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276421 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276421&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309674 378158091 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167415 CCOc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C27H33FN2O3/c1-4-32-20-7-5-6-18(12-20)21-13-19-15-27(2,3)25(22(19)14-23(21)28)29-26(31)33-24-16-30-10-8-17(24)9-11-30/h5-7,12-14,17,24-25H,4,8-11,15-16H2,1-3H3,(H,29,31) KDYTZJUKPMIDNX-UHFFFAOYSA-N 276422 (S)-quinuclidin-3-yl (5-(3-ethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 376 Mannosyl-oligosaccharide glucosidase 2.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276422 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276422&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309675 378158092 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167416 CCCOc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C28H35FN2O3/c1-4-12-33-21-7-5-6-19(13-21)22-14-20-16-28(2,3)26(23(20)15-24(22)29)30-27(32)34-25-17-31-10-8-18(25)9-11-31/h5-7,13-15,18,25-26H,4,8-12,16-17H2,1-3H3,(H,30,32) DDLLQPSCNAAUMQ-UHFFFAOYSA-N 276423 (S)-quinuclidin-3-yl (6-fluoro-2,2-dimethyl-5-(3-propoxyphenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 377 Mannosyl-oligosaccharide glucosidase 1.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276423 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276423&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309676 378158093 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167417 CC(C)Oc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C28H35FN2O3/c1-17(2)33-21-7-5-6-19(12-21)22-13-20-15-28(3,4)26(23(20)14-24(22)29)30-27(32)34-25-16-31-10-8-18(25)9-11-31/h5-7,12-14,17-18,25-26H,8-11,15-16H2,1-4H3,(H,30,32) FDFZRHHOXQJIAW-UHFFFAOYSA-N 276424 (S)-quinuclidin-3-yl (6-fluoro-5-(3-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 378 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276424 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276424&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309677 378158094 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167418 CCCCOc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C29H37FN2O3/c1-4-5-13-34-22-8-6-7-20(14-22)23-15-21-17-29(2,3)27(24(21)16-25(23)30)31-28(33)35-26-18-32-11-9-19(26)10-12-32/h6-8,14-16,19,26-27H,4-5,9-13,17-18H2,1-3H3,(H,31,33) OVVXYINOIKTGIN-UHFFFAOYSA-N 276425 (S)-quinuclidin-3-yl (5-(3-butoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 379 Mannosyl-oligosaccharide glucosidase 0.600 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276425 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276425&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309678 378158095 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167419 CC(C)COc1cccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C29H37FN2O3/c1-18(2)17-34-22-7-5-6-20(12-22)23-13-21-15-29(3,4)27(24(21)14-25(23)30)31-28(33)35-26-16-32-10-8-19(26)9-11-32/h5-7,12-14,18-19,26-27H,8-11,15-17H2,1-4H3,(H,31,33) QRHSMNNMIMSEJB-UHFFFAOYSA-N 276426 (S)-quinuclidin-3-yl (6-fluoro-5-(3-isobutoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 380 Mannosyl-oligosaccharide glucosidase 1.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276426 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276426&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309679 378158096 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167420 COc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c(OC)c1 InChI=1S/C27H33FN2O4/c1-27(2)14-17-11-21(19-6-5-18(32-3)12-23(19)33-4)22(28)13-20(17)25(27)29-26(31)34-24-15-30-9-7-16(24)8-10-30/h5-6,11-13,16,24-25H,7-10,14-15H2,1-4H3,(H,29,31) PWTIEBACKNXBQV-UHFFFAOYSA-N 276427 (S)-quinuclidin-3-yl (5-(2,4-dimethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 381 Mannosyl-oligosaccharide glucosidase 1.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276427 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276427&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309680 378158097 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167421 COc1ccc(OC)c(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C27H33FN2O4/c1-27(2)14-17-11-20(21-12-18(32-3)5-6-23(21)33-4)22(28)13-19(17)25(27)29-26(31)34-24-15-30-9-7-16(24)8-10-30/h5-6,11-13,16,24-25H,7-10,14-15H2,1-4H3,(H,29,31) VWDRCNCNTSFCMS-UHFFFAOYSA-N 276428 (S)-quinuclidin-3-yl (5-(2,5-dimethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 382 Mannosyl-oligosaccharide glucosidase 0.500 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276428 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276428&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309681 378158098 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167422 COc1cccc(OC)c1-c1cc2c(cc1F)C(NC(=O)O[C@H]1CN3CCC1CC3)C(C)(C)C2 InChI=1S/C27H33FN2O4/c1-27(2)14-17-12-19(24-21(32-3)6-5-7-22(24)33-4)20(28)13-18(17)25(27)29-26(31)34-23-15-30-10-8-16(23)9-11-30/h5-7,12-13,16,23,25H,8-11,14-15H2,1-4H3,(H,29,31) ZNEJRLVXBPYDTB-UHFFFAOYSA-N 276429 (S)-quinuclidin-3-yl (5-(2,6-dimethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 383 Mannosyl-oligosaccharide glucosidase 1.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276429&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302391 378158099 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167423 COc1cc(OC)cc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1 InChI=1S/C27H33FN2O4/c1-27(2)14-18-11-21(17-9-19(32-3)12-20(10-17)33-4)23(28)13-22(18)25(27)29-26(31)34-24-15-30-7-5-16(24)6-8-30/h9-13,16,24-25H,5-8,14-15H2,1-4H3,(H,29,31) CFIAQOHGCSNYDZ-UHFFFAOYSA-N 276430 (S)-quinuclidin-3-yl (5-(3,5-dimethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 384 Mannosyl-oligosaccharide glucosidase 1.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276430 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276430&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309682 378158100 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167424 COc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1OC InChI=1S/C27H33FN2O4/c1-27(2)14-18-11-19(17-5-6-22(32-3)23(12-17)33-4)21(28)13-20(18)25(27)29-26(31)34-24-15-30-9-7-16(24)8-10-30/h5-6,11-13,16,24-25H,7-10,14-15H2,1-4H3,(H,29,31) NKBACODWCYGPBZ-UHFFFAOYSA-N 276431 (S)-quinuclidin-3-yl (5-(3,4-dimethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 385 Mannosyl-oligosaccharide glucosidase 6.90 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276431&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302388 378158101 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167425 COc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c(Cl)c1 InChI=1S/C26H30ClFN2O3/c1-26(2)13-16-10-20(18-5-4-17(32-3)11-21(18)27)22(28)12-19(16)24(26)29-25(31)33-23-14-30-8-6-15(23)7-9-30/h4-5,10-12,15,23-24H,6-9,13-14H2,1-3H3,(H,29,31) FTIYKUVJABTRPU-UHFFFAOYSA-N 276432 (S)-quinuclidin-3-yl (5-(2-chloro-4-methoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 386 Mannosyl-oligosaccharide glucosidase 0.200 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276432 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276432&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302381 378158102 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167426 CCOc1ccc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc1F InChI=1S/C27H32F2N2O3/c1-4-33-23-6-5-17(12-22(23)29)19-11-18-14-27(2,3)25(20(18)13-21(19)28)30-26(32)34-24-15-31-9-7-16(24)8-10-31/h5-6,11-13,16,24-25H,4,7-10,14-15H2,1-3H3,(H,30,32) FCBFRIXIJJLCHN-UHFFFAOYSA-N 276433 (S)-quinuclidin-3-yl (5-(4-ethoxy-3-fluorophenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 387 Mannosyl-oligosaccharide glucosidase 1.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276433 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276433&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309683 378158103 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167427 Cc1cc(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)cc(C)c1OC(C)C InChI=1S/C30H39FN2O3/c1-17(2)35-27-18(3)11-21(12-19(27)4)23-13-22-15-30(5,6)28(24(22)14-25(23)31)32-29(34)36-26-16-33-9-7-20(26)8-10-33/h11-14,17,20,26,28H,7-10,15-16H2,1-6H3,(H,32,34) DNTDLZCLAINRCC-UHFFFAOYSA-N 276434 (S)-quinuclidin-3-yl (6-fluoro-5-(4-isopropoxy-3,5-dimethylphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 388 Mannosyl-oligosaccharide glucosidase 11.5 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276434 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276434&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309684 378158104 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167428 O=C(NC1c2ccc(-c3ccc(F)cc3)cc2CC12CC2)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27FN2O2/c26-20-4-1-16(2-5-20)18-3-6-21-19(13-18)14-25(9-10-25)23(21)27-24(29)30-22-15-28-11-7-17(22)8-12-28/h1-6,13,17,22-23H,7-12,14-15H2,(H,27,29) WRXMJWVMDYHABH-UHFFFAOYSA-N 276436 (S)-quinuclidin-3-yl (5'-(4-fluorophenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 389 Mannosyl-oligosaccharide glucosidase 19.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276436 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276436&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302200 378158105 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167429 O=C(NC1c2ccc(-c3ccc(Cl)cc3)cc2CC12CC2)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27ClN2O2/c26-20-4-1-16(2-5-20)18-3-6-21-19(13-18)14-25(9-10-25)23(21)27-24(29)30-22-15-28-11-7-17(22)8-12-28/h1-6,13,17,22-23H,7-12,14-15H2,(H,27,29) DGOXGRBSCPKLSZ-UHFFFAOYSA-N 276438 (S)-quinuclidin-3-yl (5'-(4-chlorophenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 390 Mannosyl-oligosaccharide glucosidase 18.6 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276438 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276438&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302243 378158106 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167430 O=C(NC1c2ccc(-c3ccc(C(F)(F)F)cc3)cc2CC12CC2)O[C@H]1CN2CCC1CC2 InChI=1S/C26H27F3N2O2/c27-26(28,29)20-4-1-16(2-5-20)18-3-6-21-19(13-18)14-25(9-10-25)23(21)30-24(32)33-22-15-31-11-7-17(22)8-12-31/h1-6,13,17,22-23H,7-12,14-15H2,(H,30,32) VIYJTDZTSGKEJA-UHFFFAOYSA-N 276440 (S)-quinuclidin-3-yl (5'-(4-(trifluoromethyl)phenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 391 Mannosyl-oligosaccharide glucosidase 21.4 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276440 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276440&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302188 378158107 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167431 O=C(NC1c2ccc(-c3ccc(OC(F)(F)F)cc3)cc2CC12CC2)O[C@H]1CN2CCC1CC2 InChI=1S/C26H27F3N2O3/c27-26(28,29)34-20-4-1-16(2-5-20)18-3-6-21-19(13-18)14-25(9-10-25)23(21)30-24(32)33-22-15-31-11-7-17(22)8-12-31/h1-6,13,17,22-23H,7-12,14-15H2,(H,30,32) XNKIFCFIEWMYKQ-UHFFFAOYSA-N 276442 (S)-quinuclidin-3-yl (5'-(4-(trifluoromethoxy)phenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 392 Mannosyl-oligosaccharide glucosidase 10.2 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276442 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276442&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309685 378158108 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167432 O=C(NC1c2ccc(-c3cccc(Cl)c3)cc2CC12CC2)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27ClN2O2/c26-20-3-1-2-17(13-20)18-4-5-21-19(12-18)14-25(8-9-25)23(21)27-24(29)30-22-15-28-10-6-16(22)7-11-28/h1-5,12-13,16,22-23H,6-11,14-15H2,(H,27,29) KJDBYAZWWRBXPU-UHFFFAOYSA-N 276443 (S)-quinuclidin-3-yl (5'-(3-chlorophenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 393 Mannosyl-oligosaccharide glucosidase 4.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276443 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276443&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302420 378158109 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167433 O=C(NC1c2ccc(-c3cccc(C(F)(F)F)c3)cc2CC12CC2)O[C@H]1CN2CCC1CC2 InChI=1S/C26H27F3N2O2/c27-26(28,29)20-3-1-2-17(13-20)18-4-5-21-19(12-18)14-25(8-9-25)23(21)30-24(32)33-22-15-31-10-6-16(22)7-11-31/h1-5,12-13,16,22-23H,6-11,14-15H2,(H,30,32) AVKOOEXQOLHWBS-UHFFFAOYSA-N 276444 (S)-quinuclidin-3-yl (5'-(3-(trifluoromethyl)phenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 394 Mannosyl-oligosaccharide glucosidase 5.60 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276444 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276444&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302227 378158110 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167434 COCCOc1ccc(-c2ccc3c(c2)CC2(CC2)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C28H34N2O4/c1-32-14-15-33-23-5-2-19(3-6-23)21-4-7-24-22(16-21)17-28(10-11-28)26(24)29-27(31)34-25-18-30-12-8-20(25)9-13-30/h2-7,16,20,25-26H,8-15,17-18H2,1H3,(H,29,31) MYJVOEKMUBZYMX-UHFFFAOYSA-N 276445 (S)-quinuclidin-3-yl (5'-(4-(2-methoxyethoxy)phenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 395 Mannosyl-oligosaccharide glucosidase 2.40 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276445 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276445&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309686 378158111 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167435 COCCOc1cccc(-c2ccc3c(c2)CC2(CC2)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C28H34N2O4/c1-32-13-14-33-23-4-2-3-20(16-23)21-5-6-24-22(15-21)17-28(9-10-28)26(24)29-27(31)34-25-18-30-11-7-19(25)8-12-30/h2-6,15-16,19,25-26H,7-14,17-18H2,1H3,(H,29,31) VNOMUFMXIPIJDZ-UHFFFAOYSA-N 276446 (S)-quinuclidin-3-yl (5'-(3-(2-methoxyethoxy)phenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 396 Mannosyl-oligosaccharide glucosidase 2.70 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276446 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276446&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309687 378158112 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167436 COCOc1ccc(-c2ccc3c(c2)CC2(CC2)C3NC(=O)O[C@H]2CN3CCC2CC3)cc1 InChI=1S/C27H32N2O4/c1-31-17-32-22-5-2-18(3-6-22)20-4-7-23-21(14-20)15-27(10-11-27)25(23)28-26(30)33-24-16-29-12-8-19(24)9-13-29/h2-7,14,19,24-25H,8-13,15-17H2,1H3,(H,28,30) CLQZVKWQCARUAD-UHFFFAOYSA-N 276447 (S)-quinuclidin-3-yl (5'-(4-(methoxymethoxy)phenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 397 Mannosyl-oligosaccharide glucosidase 0.800 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276447 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276447&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302360 378158113 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167437 COCOc1cccc(-c2ccc3c(c2)CC2(CC2)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H32N2O4/c1-31-17-32-22-4-2-3-19(14-22)20-5-6-23-21(13-20)15-27(9-10-27)25(23)28-26(30)33-24-16-29-11-7-18(24)8-12-29/h2-6,13-14,18,24-25H,7-12,15-17H2,1H3,(H,28,30) OLTKWAHNBPZFQG-UHFFFAOYSA-N 276448 (S)-quinuclidin-3-yl (5'-(3-(methoxymethoxy)phenyl)-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-1'-yl)carbamate::US12522602, Example 398 Mannosyl-oligosaccharide glucosidase 0.900 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276448 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276448&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302220 378158114 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167438 CC1(C)CC(NC(=O)O[C@H]2CN3CCC2CC3)c2ccc(-c3cccc(Cl)c3)cc21 InChI=1S/C25H29ClN2O2/c1-25(2)14-22(27-24(29)30-23-15-28-10-8-16(23)9-11-28)20-7-6-18(13-21(20)25)17-4-3-5-19(26)12-17/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,27,29) PNHBVHNOXLVVDG-UHFFFAOYSA-N 276449 (S)-quinuclidin-3-yl (5-(3-chlorophenyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 399 Mannosyl-oligosaccharide glucosidase 104 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276449 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276449&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309688 378158115 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 167439 CC1(C)CC(NC(=O)O[C@H]2CN3CCC2CC3)c2ccc(-c3ccccc3Cl)cc21 InChI=1S/C25H29ClN2O2/c1-25(2)14-22(27-24(29)30-23-15-28-11-9-16(23)10-12-28)19-8-7-17(13-20(19)25)18-5-3-4-6-21(18)26/h3-8,13,16,22-23H,9-12,14-15H2,1-2H3,(H,27,29) GMHKOJUDGQYUCC-UHFFFAOYSA-N 276450 (S)-quinuclidin-3-yl (5-(2-chlorophenyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 400 Mannosyl-oligosaccharide glucosidase 65.6 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276450 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276450&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309689 378158116 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190825 CC1(C)CC(NC(=O)O[C@H]2CN3CCC2CC3)c2ccc(-c3cccc(C(F)(F)F)c3)cc21 InChI=1S/C26H29F3N2O2/c1-25(2)14-22(30-24(32)33-23-15-31-10-8-16(23)9-11-31)20-7-6-18(13-21(20)25)17-4-3-5-19(12-17)26(27,28)29/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,30,32) QATOYARVOQSCEE-UHFFFAOYSA-N 276451 (S)-quinuclidin-3-yl (3,3-dimethyl-5-(3-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 401 Mannosyl-oligosaccharide glucosidase 73.0 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276451&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302314 378158117 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190826 CC1(C)CC(NC(=O)O[C@H]2CN3CCC2CC3)c2ccc(-c3cccc(OC(F)(F)F)c3)cc21 InChI=1S/C26H29F3N2O3/c1-25(2)14-22(30-24(32)33-23-15-31-10-8-16(23)9-11-31)20-7-6-18(13-21(20)25)17-4-3-5-19(12-17)34-26(27,28)29/h3-7,12-13,16,22-23H,8-11,14-15H2,1-2H3,(H,30,32) NCRJKZJZWKSEOU-UHFFFAOYSA-N 276452 (S)-quinuclidin-3-yl (3,3-dimethyl-5-(3-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 402 Mannosyl-oligosaccharide glucosidase 74.5 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276452 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276452&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302276 378158118 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190827 CC1(C)CC(NC(=O)O[C@H]2CN3CCC2CC3)c2ccc(-c3ccccc3OC(F)(F)F)cc21 InChI=1S/C26H29F3N2O3/c1-25(2)14-21(30-24(32)33-23-15-31-11-9-16(23)10-12-31)19-8-7-17(13-20(19)25)18-5-3-4-6-22(18)34-26(27,28)29/h3-8,13,16,21,23H,9-12,14-15H2,1-2H3,(H,30,32) BTBKNHUKXNKWPA-UHFFFAOYSA-N 276453 (S)-quinuclidin-3-yl (3,3-dimethyl-5-(2-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 403 Mannosyl-oligosaccharide glucosidase 155 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276453 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276453&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302424 378158119 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190828 O=C(NC1COc2cc(-c3cccc(C(F)(F)F)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H23F3N2O3/c24-23(25,26)17-3-1-2-15(10-17)16-4-5-18-19(13-30-20(18)11-16)27-22(29)31-21-12-28-8-6-14(21)7-9-28/h1-5,10-11,14,19,21H,6-9,12-13H2,(H,27,29) YCYMKGFHPFZJGP-UHFFFAOYSA-N 276454 (S)-quinuclidin-3-yl (6-(3-(trifluoromethyl)phenyl)-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 404 Mannosyl-oligosaccharide glucosidase 5.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276454 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276454&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302322 378158120 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190829 O=C(NC1COc2cc(-c3cccc(OC(F)(F)F)c3)ccc21)O[C@H]1CN2CCC1CC2 InChI=1S/C23H23F3N2O4/c24-23(25,26)32-17-3-1-2-15(10-17)16-4-5-18-19(13-30-20(18)11-16)27-22(29)31-21-12-28-8-6-14(21)7-9-28/h1-5,10-11,14,19,21H,6-9,12-13H2,(H,27,29) YKILDLLLJASRKB-UHFFFAOYSA-N 276455 (S)-quinuclidin-3-yl (6-(3-(trifluoromethoxy)phenyl)-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 405 Mannosyl-oligosaccharide glucosidase 7.10 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276455 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276455&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309690 378158121 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190830 CC1(C)Oc2ccc(-c3cccc(F)c3)cc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C24H27FN2O3/c1-24(2)22(26-23(28)29-21-14-27-10-8-15(21)9-11-27)19-13-17(6-7-20(19)30-24)16-4-3-5-18(25)12-16/h3-7,12-13,15,21-22H,8-11,14H2,1-2H3,(H,26,28) OIWDDCXRLMAAOF-UHFFFAOYSA-N 276456 (S)-quinuclidin-3-yl (5-(3-fluorophenyl)-2,2-dimethyl-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 406 Mannosyl-oligosaccharide glucosidase 31.1 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276456 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276456&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309691 378158122 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190831 CC1(C)Oc2cc(-c3cccc(F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C24H27FN2O3/c1-24(2)22(26-23(28)29-21-14-27-10-8-15(21)9-11-27)19-7-6-17(13-20(19)30-24)16-4-3-5-18(25)12-16/h3-7,12-13,15,21-22H,8-11,14H2,1-2H3,(H,26,28) VXJQMNKKVODTRD-UHFFFAOYSA-N 276457 (S)-quinuclidin-3-yl (6-(3-fluorophenyl)-2,2-dimethyl-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 407 Mannosyl-oligosaccharide glucosidase 4.80 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276457 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276457&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309692 378158123 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190832 CC1(C)Oc2cc(-c3cccc(Cl)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C24H27ClN2O3/c1-24(2)22(26-23(28)29-21-14-27-10-8-15(21)9-11-27)19-7-6-17(13-20(19)30-24)16-4-3-5-18(25)12-16/h3-7,12-13,15,21-22H,8-11,14H2,1-2H3,(H,26,28) ZAPUICVGWLCKRQ-UHFFFAOYSA-N 276458 (S)-quinuclidin-3-yl (6-(3-chlorophenyl)-2,2-dimethyl-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 408 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276458 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276458&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309693 378158124 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190833 CC1(C)Oc2cc(-c3cccc(C(F)(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27F3N2O3/c1-24(2)22(29-23(31)32-21-14-30-10-8-15(21)9-11-30)19-7-6-17(13-20(19)33-24)16-4-3-5-18(12-16)25(26,27)28/h3-7,12-13,15,21-22H,8-11,14H2,1-2H3,(H,29,31) BEVFOWXVSANWRE-UHFFFAOYSA-N 276459 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(3-(trifluoromethyl)phenyl)-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 409 Mannosyl-oligosaccharide glucosidase 3.30 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276459 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276459&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130302460 378158125 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190834 CC1(C)Oc2cc(-c3cccc(OC(F)(F)F)c3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2 InChI=1S/C25H27F3N2O4/c1-24(2)22(29-23(31)32-21-14-30-10-8-15(21)9-11-30)19-7-6-17(13-20(19)34-24)16-4-3-5-18(12-16)33-25(26,27)28/h3-7,12-13,15,21-22H,8-11,14H2,1-2H3,(H,29,31) NRUXWBZCLUZZDO-UHFFFAOYSA-N 276460 (S)-quinuclidin-3-yl (2,2-dimethyl-6-(3-(trifluoromethoxy)phenyl)-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 410 Mannosyl-oligosaccharide glucosidase 3.00 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276460 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276460&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309694 378158126 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5 190835 COCCOc1cccc(-c2ccc3c(c2)OC(C)(C)C3NC(=O)O[C@H]2CN3CCC2CC3)c1 InChI=1S/C27H34N2O5/c1-27(2)25(28-26(30)33-24-17-29-11-9-18(24)10-12-29)22-8-7-20(16-23(22)34-27)19-5-4-6-21(15-19)32-14-13-31-3/h4-8,15-16,18,24-25H,9-14,17H2,1-3H3,(H,28,30) NLOFMANHBUDKER-UHFFFAOYSA-N 276461 (S)-quinuclidin-3-yl (6-(3-(2-methoxyethoxy)phenyl)-2,2-dimethyl-2,3-dihydrobenzofuran-3-yl)carbamate::US12522602, Example 411 Mannosyl-oligosaccharide glucosidase 10.9 US Patent 10.7270/Q251442K US12522602 Kim, D; Joo, J; Lee, E; Han, T; Shin, S; Kwon, S; Kim, J 1/13/2026 5/26/2026 Yuhan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=276461 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1690&target=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=276461&enzyme=Mannosyl-oligosaccharide+glucosidase&column=ki&startPg=0&Increment=50&submit=Search 130309695 378158127 1 MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGRWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQALESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGSEQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPRLHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDLRCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTKAVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSRHLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARAAKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY Mannosyl-oligosaccharide glucosidase MOGS_HUMAN Q13724 A8K938 F5H6D0 Q17RN9 Q8TCT5