BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 123611 O=C(C1CCNCC1)N1CC[C@@H]2CC1c1cc(-c3cccc(OC(F)(F)F)c3)ccc12 InChI=1S/C24H25F3N2O2/c25-24(26,27)31-19-3-1-2-16(12-19)17-4-5-20-18-8-11-29(22(14-18)21(20)13-17)23(30)15-6-9-28-10-7-15/h1-5,12-13,15,18,22,28H,6-11,14H2 WIXVSONBRNMVHP-UHFFFAOYSA-N 75879 US20250387403, Example Table1.1 Sigma intracellular receptor 2 Homo sapiens 35.4 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75879 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75879&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597771 252653072 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123612 O=C(C1CCNCC1)N1CC[C@H]2CC1c1cc(-c3cccc(OC(F)(F)F)c3)ccc12 InChI=1S/C24H25F3N2O2/c25-24(26,27)31-19-3-1-2-16(12-19)17-4-5-20-18-8-11-29(22(14-18)21(20)13-17)23(30)15-6-9-28-10-7-15/h1-5,12-13,15,18,22,28H,6-11,14H2 WIXVSONBRNMVHP-UHFFFAOYSA-N 77582 US20250387403, Example Table1.2 Sigma intracellular receptor 2 Homo sapiens 37.1 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77582 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77582&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597747 252654613 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123613 O=C(C1CCN(CCO)CC1)N1CCC2CC1c1cc(-c3cccc(C(F)(F)F)c3)ccc12 InChI=1S/C26H29F3N2O2/c27-26(28,29)21-3-1-2-18(14-21)19-4-5-22-20-8-11-31(24(16-20)23(22)15-19)25(33)17-6-9-30(10-7-17)12-13-32/h1-5,14-15,17,20,24,32H,6-13,16H2 VXRCTLWGVSPXOL-UHFFFAOYSA-N 77583 US20250387403, Example Table1.3 Sigma intracellular receptor 2 Homo sapiens 32.3 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77583 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77583&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289502 252654614 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123614 CN1CCC(C(=O)N2CCC3CC2c2cc(-c4cccc(OC(F)(F)F)c4)ccc23)CC1 InChI=1S/C25H27F3N2O2/c1-29-10-7-16(8-11-29)24(31)30-12-9-19-15-23(30)22-14-18(5-6-21(19)22)17-3-2-4-20(13-17)32-25(26,27)28/h2-6,13-14,16,19,23H,7-12,15H2,1H3 GMEDTCVXKNAWNU-UHFFFAOYSA-N 77584 US20250387403, Example Table1.4 Sigma intracellular receptor 2 Homo sapiens 30.4 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77584 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77584&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170341218 252654615 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123615 CN1CCC(C(=O)N2CCC3CC2c2cc(-c4ccc(C(F)(F)F)cc4)ccc23)CC1 InChI=1S/C25H27F3N2O/c1-29-11-8-17(9-12-29)24(31)30-13-10-19-15-23(30)22-14-18(4-7-21(19)22)16-2-5-20(6-3-16)25(26,27)28/h2-7,14,17,19,23H,8-13,15H2,1H3 ISQCBLHLZAKTIV-UHFFFAOYSA-N 77586 US20250387403, Example Table1.5 Sigma intracellular receptor 2 Homo sapiens 32.8 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77586 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77586&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289503 252654617 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123616 CN1CCC(C(=O)N2CCC3C[C@@H]2c2cc(-c4ccc(C(F)(F)F)cc4)ccc23)CC1 InChI=1S/C25H27F3N2O/c1-29-11-8-17(9-12-29)24(31)30-13-10-19-15-23(30)22-14-18(4-7-21(19)22)16-2-5-20(6-3-16)25(26,27)28/h2-7,14,17,19,23H,8-13,15H2,1H3 ISQCBLHLZAKTIV-UHFFFAOYSA-N 77590 US20250387403, Example Table1.6 Sigma intracellular receptor 2 Homo sapiens 35.1 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77590 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77590&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289504 252654621 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123617 O=C(C1CCN(CCO)CC1)N1CCC2C[C@H]1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C26H29F3N2O2/c27-26(28,29)21-4-1-17(2-5-21)19-3-6-22-20-9-12-31(24(16-20)23(22)15-19)25(33)18-7-10-30(11-8-18)13-14-32/h1-6,15,18,20,24,32H,7-14,16H2 YTTLYYZNHHKANY-UHFFFAOYSA-N 77591 US20250387403, Example Table1.7 Sigma intracellular receptor 2 Homo sapiens 13.6 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77591 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77591&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289505 252654622 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123618 Cc1ccc(-c2ccc3c(c2)[C@@H]2CC3CCN2C(=O)C2CCN(CCO)CC2)cc1 InChI=1S/C26H32N2O2/c1-18-2-4-19(5-3-18)21-6-7-23-22-10-13-28(25(17-22)24(23)16-21)26(30)20-8-11-27(12-9-20)14-15-29/h2-7,16,20,22,25,29H,8-15,17H2,1H3 URVCRYDPLFNDCG-UHFFFAOYSA-N 77592 US20250387403, Example Table1.8 Sigma intracellular receptor 2 Homo sapiens 834 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77592 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77592&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289506 252654623 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123619 CS(=O)(=O)c1cccc(-c2ccc3c(c2)C2C[C@H]3CCN2C(=O)C2CCN(CCO)CC2)c1 InChI=1S/C26H32N2O4S/c1-33(31,32)22-4-2-3-19(15-22)20-5-6-23-21-9-12-28(25(17-21)24(23)16-20)26(30)18-7-10-27(11-8-18)13-14-29/h2-6,15-16,18,21,25,29H,7-14,17H2,1H3 KYRYAFVCBFROBG-UHFFFAOYSA-N 77593 US20250387403, Example Table1.9 Sigma intracellular receptor 2 Homo sapiens 277 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77593 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77593&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289507 252654624 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123620 O=C(C1CCN(CCCO)CC1)N1CCC2CC1c1cc(-c3ccc(OC(F)(F)F)cc3)ccc12 InChI=1S/C27H31F3N2O3/c28-27(29,30)35-22-5-2-18(3-6-22)20-4-7-23-21-10-14-32(25(17-21)24(23)16-20)26(34)19-8-12-31(13-9-19)11-1-15-33/h2-7,16,19,21,25,33H,1,8-15,17H2 AYPRJDJJGMHWLX-UHFFFAOYSA-N 77594 US20250387403, Example Table1.10 Sigma intracellular receptor 2 Homo sapiens 79.9 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77594 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77594&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289508 252654625 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123621 O=C(C1CCN(CCCO)CC1)N1CC[C@@H]2CC1c1cc(-c3cccc(OC(F)(F)F)c3)ccc12 InChI=1S/C27H31F3N2O3/c28-27(29,30)35-22-4-1-3-19(15-22)20-5-6-23-21-9-13-32(25(17-21)24(23)16-20)26(34)18-7-11-31(12-8-18)10-2-14-33/h1,3-6,15-16,18,21,25,33H,2,7-14,17H2 ZLJSHDGEHPORQA-UHFFFAOYSA-N 77595 US20250387403, Example Table1.11 Sigma intracellular receptor 2 Homo sapiens 264 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77595 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77595&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289509 252654626 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123622 O=C(N1CCN(CCO)CC1)N1CCC2C[C@H]1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C25H28F3N3O2/c26-25(27,28)20-4-1-17(2-5-20)18-3-6-21-19-7-8-31(23(16-19)22(21)15-18)24(33)30-11-9-29(10-12-30)13-14-32/h1-6,15,19,23,32H,7-14,16H2 OJLBTEXNOIGSTG-UHFFFAOYSA-N 77597 US20250387403, Example Table1.12 Sigma intracellular receptor 2 Homo sapiens 955 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77597 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77597&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170402719 252654628 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123623 COCCN1CCC(C(=O)N2CCC3C[C@H]2c2cc(-c4ccc(C(F)(F)F)cc4)ccc23)CC1 InChI=1S/C27H31F3N2O2/c1-34-15-14-31-11-8-19(9-12-31)26(33)32-13-10-21-17-25(32)24-16-20(4-7-23(21)24)18-2-5-22(6-3-18)27(28,29)30/h2-7,16,19,21,25H,8-15,17H2,1H3 WWNDFNWSVGNCGL-UHFFFAOYSA-N 77598 US20250387403, Example Table1.13 Sigma intracellular receptor 2 Homo sapiens 10.3 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77598 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77598&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170403626 252654629 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123624 O=C(C1CCN(CCCO)CC1)N1CCC2C[C@H]1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C27H31F3N2O2/c28-27(29,30)22-5-2-18(3-6-22)20-4-7-23-21-10-14-32(25(17-21)24(23)16-20)26(34)19-8-12-31(13-9-19)11-1-15-33/h2-7,16,19,21,25,33H,1,8-15,17H2 IIYYYENWQYAWIR-UHFFFAOYSA-N 77599 US20250387403, Example Table1.14 Sigma intracellular receptor 2 Homo sapiens 7.70 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77599 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77599&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289510 252654630 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123625 COCCCN1CC(C(=O)N2CCC3CC2c2cc(-c4ccc(C(F)(F)F)cc4)ccc23)C1 InChI=1S/C26H29F3N2O2/c1-33-12-2-10-30-15-20(16-30)25(32)31-11-9-19-14-24(31)23-13-18(5-8-22(19)23)17-3-6-21(7-4-17)26(27,28)29/h3-8,13,19-20,24H,2,9-12,14-16H2,1H3 PRRBVSNRVIKTMH-UHFFFAOYSA-N 77600 US20250387403, Example Table1.15 Sigma intracellular receptor 2 Homo sapiens 4.60 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77600 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77600&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289511 252654631 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123626 COCCN1CC(C(=O)N2CCC3C[C@H]2c2cc(-c4ccc(C(F)(F)F)cc4)ccc23)C1 InChI=1S/C25H27F3N2O2/c1-32-11-10-29-14-19(15-29)24(31)30-9-8-18-13-23(30)22-12-17(4-7-21(18)22)16-2-5-20(6-3-16)25(26,27)28/h2-7,12,18-19,23H,8-11,13-15H2,1H3 KETFKDYGLYZLHL-UHFFFAOYSA-N 77601 US20250387403, Example Table1.16 Sigma intracellular receptor 2 Homo sapiens 17.6 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77601 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77601&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170402950 252654632 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123627 O=C(C1CN(CCO)C1)N1CCC2C[C@H]1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C24H25F3N2O2/c25-24(26,27)19-4-1-15(2-5-19)16-3-6-20-17-7-8-29(22(12-17)21(20)11-16)23(31)18-13-28(14-18)9-10-30/h1-6,11,17-18,22,30H,7-10,12-14H2 NIAFQHUTNZCVTH-UHFFFAOYSA-N 77602 US20250387403, Example Table1.17 Sigma intracellular receptor 2 Homo sapiens 15.3 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77602 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77602&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597789 252654633 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123628 O=C(C1CN(CCCO)C1)N1CCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C25H27F3N2O2/c26-25(27,28)20-5-2-16(3-6-20)17-4-7-21-18-8-10-30(23(13-18)22(21)12-17)24(32)19-14-29(15-19)9-1-11-31/h2-7,12,18-19,23,31H,1,8-11,13-15H2 AWRXSPQHWZZIHE-UHFFFAOYSA-N 77603 US20250387403, Example Table1.18 Sigma intracellular receptor 2 Homo sapiens 11.9 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77603 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77603&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597762 252654634 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123629 O=C(C1CN(CCCF)C1)N1CCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C25H26F4N2O/c26-9-1-10-30-14-19(15-30)24(32)31-11-8-18-13-23(31)22-12-17(4-7-21(18)22)16-2-5-20(6-3-16)25(27,28)29/h2-7,12,18-19,23H,1,8-11,13-15H2 OGKSELHIGPDNEA-UHFFFAOYSA-N 77604 US20250387403, Example Table1.19 Sigma intracellular receptor 2 Homo sapiens 14.7 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77604 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77604&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289512 252654635 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123630 OCCCN1CCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C21H22F3NO/c22-21(23,24)17-5-2-14(3-6-17)15-4-7-18-16-8-10-25(9-1-11-26)20(13-16)19(18)12-15/h2-7,12,16,20,26H,1,8-11,13H2 DYYGKMZHHOOCGT-UHFFFAOYSA-N 77607 US20250387403, Example Table1.20 Sigma intracellular receptor 2 Homo sapiens 30.6 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77607 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77607&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289513 252654638 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123631 CC(C)Oc1ccc(-c2ccc3c(c2)C2C[C@H]3CCN2CCCO)cc1 InChI=1S/C23H29NO2/c1-16(2)26-20-7-4-17(5-8-20)18-6-9-21-19-10-12-24(11-3-13-25)23(15-19)22(21)14-18/h4-9,14,16,19,23,25H,3,10-13,15H2,1-2H3 WJJWRNAAIKIHHE-UHFFFAOYSA-N 77608 US20250387403, Example Table1.21 Sigma intracellular receptor 2 Homo sapiens 65.9 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77608 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77608&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289514 252654639 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123632 OCCCN1CC[C@@H]2CC1c1cc(-c3ccnc(F)c3)ccc12 InChI=1S/C19H21FN2O/c20-19-12-14(4-6-21-19)13-2-3-16-15-5-8-22(7-1-9-23)18(11-15)17(16)10-13/h2-4,6,10,12,15,18,23H,1,5,7-9,11H2 FIEZIMGZPFNZAP-UHFFFAOYSA-N 77609 US20250387403, Example Table1.22 Sigma intracellular receptor 2 Homo sapiens 802 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77609 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77609&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289515 252654640 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123633 Cc1ccc(-c2ccc3c(c2)C2C[C@H]3CCN2CCCO)cc1 InChI=1S/C21H25NO/c1-15-3-5-16(6-4-15)17-7-8-19-18-9-11-22(10-2-12-23)21(14-18)20(19)13-17/h3-8,13,18,21,23H,2,9-12,14H2,1H3 IDRWZOBISMPKDC-UHFFFAOYSA-N 77687 US20250387403, Example Table1.23 Sigma intracellular receptor 2 Homo sapiens 1181 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77687 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77687&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289516 252654682 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123634 OCCCN1CC[C@@H]2CC1c1cc(-c3cccc(OC(F)(F)F)c3)ccc12 InChI=1S/C21H22F3NO2/c22-21(23,24)27-17-4-1-3-14(11-17)15-5-6-18-16-7-9-25(8-2-10-26)20(13-16)19(18)12-15/h1,3-6,11-12,16,20,26H,2,7-10,13H2 VHDRRMWVSJCLLM-UHFFFAOYSA-N 77798 US20250387403, Example Table1.24 Sigma intracellular receptor 2 Homo sapiens 48.3 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77798 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77798&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289517 252654704 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123635 CS(=O)(=O)c1cccc(-c2ccc3c(c2)C2C[C@H]3CCN2CCCO)c1 InChI=1S/C21H25NO3S/c1-26(24,25)18-5-2-4-15(12-18)16-6-7-19-17-8-10-22(9-3-11-23)21(14-17)20(19)13-16/h2,4-7,12-13,17,21,23H,3,8-11,14H2,1H3 SGNSISVIJZXPBI-UHFFFAOYSA-N 77835 US20250387403, Example Table1.25 Sigma intracellular receptor 2 Homo sapiens 1848 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77835 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77835&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289518 252654709 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123636 N[C@H]1CC[C@@H](N2CCC3C[C@H]2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1 InChI=1S/C24H27F3N2/c25-24(26,27)18-3-1-2-15(12-18)16-4-9-21-17-10-11-29(23(14-17)22(21)13-16)20-7-5-19(28)6-8-20/h1-4,9,12-13,17,19-20,23H,5-8,10-11,14,28H2 NSNYNXHVYHCKFB-UHFFFAOYSA-N 77836 US20250387403, Example Table1.26 Sigma intracellular receptor 2 Homo sapiens 30.8 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77836 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77836&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289519 252654710 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123637 CN(C)[C@H]1CC[C@@H](N2CCC3C[C@H]2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1 InChI=1S/C26H31F3N2/c1-30(2)21-7-9-22(10-8-21)31-13-12-19-16-25(31)24-15-18(6-11-23(19)24)17-4-3-5-20(14-17)26(27,28)29/h3-6,11,14-15,19,21-22,25H,7-10,12-13,16H2,1-2H3 ZTOYCIBXBPGBKN-UHFFFAOYSA-N 77929 US20250387403, Example Table1.27 Sigma intracellular receptor 2 Homo sapiens 9.50 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77929 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77929&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597731 242053623 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123638 N[C@H]1CC[C@@H](N2CCC3CC2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1 InChI=1S/C24H27F3N2/c25-24(26,27)18-3-1-2-15(12-18)16-4-9-21-17-10-11-29(23(14-17)22(21)13-16)20-7-5-19(28)6-8-20/h1-4,9,12-13,17,19-20,23H,5-8,10-11,14,28H2 NSNYNXHVYHCKFB-UHFFFAOYSA-N 79450 US20250387403, Example Table1.28 Sigma intracellular receptor 2 Homo sapiens 7.90 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79450 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79450&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170341180 252656105 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123639 N[C@H]1CC[C@H](N2CCC3CC2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1 InChI=1S/C24H27F3N2/c25-24(26,27)18-3-1-2-15(12-18)16-4-9-21-17-10-11-29(23(14-17)22(21)13-16)20-7-5-19(28)6-8-20/h1-4,9,12-13,17,19-20,23H,5-8,10-11,14,28H2 NSNYNXHVYHCKFB-UHFFFAOYSA-N 79451 US20250387403, Example Table1.29 Sigma intracellular receptor 2 Homo sapiens 70.5 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79451&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170341180 252656106 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123640 OCCCN1CCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C21H22F3NO/c22-21(23,24)17-5-2-14(3-6-17)15-4-7-18-16-8-10-25(9-1-11-26)20(13-16)19(18)12-15/h2-7,12,16,20,26H,1,8-11,13H2 DYYGKMZHHOOCGT-UHFFFAOYSA-N 79452 US20250387403, Example Table1.30 Sigma intracellular receptor 2 Homo sapiens 11.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79452 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79452&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 123821136 252656107 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123641 OCCN1CCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C20H20F3NO/c21-20(22,23)16-4-1-13(2-5-16)14-3-6-17-15-7-8-24(9-10-25)19(12-15)18(17)11-14/h1-6,11,15,19,25H,7-10,12H2 CFONTNQODDPETI-UHFFFAOYSA-N 79454 US20250387403, Example Table1.31 Sigma intracellular receptor 2 Homo sapiens 32.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79454 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79454&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597752 252656109 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123642 FC(F)(F)c1ccc(-c2ccc3c(c2)C2CC3CCN2C2CCCC2)cc1 InChI=1S/C23H24F3N/c24-23(25,26)18-8-5-15(6-9-18)16-7-10-20-17-11-12-27(19-3-1-2-4-19)22(14-17)21(20)13-16/h5-10,13,17,19,22H,1-4,11-12,14H2 GXWCXSDDKPPYAJ-UHFFFAOYSA-N 79455 US20250387403, Example Table1.32 Sigma intracellular receptor 2 Homo sapiens 82.3 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79455 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79455&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 123521021 252656110 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123643 FC(F)(F)c1ccc(-c2ccc3c(c2)C2CC3CCN2C2CCC2)cc1 InChI=1S/C22H22F3N/c23-22(24,25)17-7-4-14(5-8-17)15-6-9-19-16-10-11-26(18-2-1-3-18)21(13-16)20(19)12-15/h4-9,12,16,18,21H,1-3,10-11,13H2 XLPGDCPWAGNEGG-UHFFFAOYSA-N 79456 US20250387403, Example Table1.33 Sigma intracellular receptor 2 Homo sapiens 213 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79456 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79456&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289520 252656111 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123644 CCCN1CCC2CC1c1cc(-c3cccc(C(F)(F)F)c3)ccc12 InChI=1S/C21H22F3N/c1-2-9-25-10-8-16-13-20(25)19-12-15(6-7-18(16)19)14-4-3-5-17(11-14)21(22,23)24/h3-7,11-12,16,20H,2,8-10,13H2,1H3 UDBILFOPWASRIZ-UHFFFAOYSA-N 79457 US20250387403, Example Table1.34 Sigma intracellular receptor 2 Homo sapiens 112 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79457 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79457&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597737 252656112 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123645 O=C(C1CCNCC1)N1CCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C24H25F3N2O/c25-24(26,27)19-4-1-15(2-5-19)17-3-6-20-18-9-12-29(22(14-18)21(20)13-17)23(30)16-7-10-28-11-8-16/h1-6,13,16,18,22,28H,7-12,14H2 BQMRZUNXJBVHDX-UHFFFAOYSA-N 79458 US20250387403, Example Table1.35 Sigma intracellular receptor 2 Homo sapiens 6.80 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79458 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79458&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170341178 252656113 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123646 CCCN1CCC(C(=O)N2CCC3CC2c2cc(-c4ccc(C(F)(F)F)cc4)ccc23)CC1 InChI=1S/C27H31F3N2O/c1-2-12-31-13-9-19(10-14-31)26(33)32-15-11-21-17-25(32)24-16-20(5-8-23(21)24)18-3-6-22(7-4-18)27(28,29)30/h3-8,16,19,21,25H,2,9-15,17H2,1H3 MBWMKQYVELPZQN-UHFFFAOYSA-N 79459 US20250387403, Example Table1.36 Sigma intracellular receptor 2 Homo sapiens 1.30 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79459 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79459&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 165413175 252656114 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123647 OC(CF)CN1CCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C21H21F4NO/c22-11-17(27)12-26-8-7-15-10-20(26)19-9-14(3-6-18(15)19)13-1-4-16(5-2-13)21(23,24)25/h1-6,9,15,17,20,27H,7-8,10-12H2 XXOKXSYVTJCJGX-UHFFFAOYSA-N 79460 US20250387403, Example Table1.37 Sigma intracellular receptor 2 Homo sapiens 34.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79460 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79460&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597775 252656115 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123648 FC(F)(F)c1cccc(-c2ccc3c(c2)C2CC3CCN2)c1 InChI=1S/C18H16F3N/c19-18(20,21)14-3-1-2-11(8-14)12-4-5-15-13-6-7-22-17(10-13)16(15)9-12/h1-5,8-9,13,17,22H,6-7,10H2 DETLFHJJGBIRGR-UHFFFAOYSA-N 79461 US20250387403, Example Table1.38 Sigma intracellular receptor 2 Homo sapiens 57.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79461 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79461&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170341204 252656116 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123649 O=C(C1CCNCC1)N1CCC2CC1c1cc(-c3cccc(C(F)(F)F)c3)ccc12 InChI=1S/C24H25F3N2O/c25-24(26,27)19-3-1-2-16(12-19)17-4-5-20-18-8-11-29(22(14-18)21(20)13-17)23(30)15-6-9-28-10-7-15/h1-5,12-13,15,18,22,28H,6-11,14H2 SWVZQSGDVFSPNF-UHFFFAOYSA-N 79463 US20250387403, Example Table1.39 Sigma intracellular receptor 2 Homo sapiens 5.50 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79463 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79463&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597728 252656117 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123650 CN1CCC(C(=O)N2CCC3CC2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1 InChI=1S/C25H27F3N2O/c1-29-10-7-16(8-11-29)24(31)30-12-9-19-15-23(30)22-14-18(5-6-21(19)22)17-3-2-4-20(13-17)25(26,27)28/h2-6,13-14,16,19,23H,7-12,15H2,1H3 BVYOKHJZYGDDAY-UHFFFAOYSA-N 79466 US20250387403, Example Table1.40 Sigma intracellular receptor 2 Homo sapiens 2.30 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79466 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79466&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597761 252656119 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123651 CC(=O)N[C@H]1CC[C@H](N2CCC3CC2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1 InChI=1S/C26H29F3N2O/c1-16(32)30-21-6-8-22(9-7-21)31-12-11-19-15-25(31)24-14-18(5-10-23(19)24)17-3-2-4-20(13-17)26(27,28)29/h2-5,10,13-14,19,21-22,25H,6-9,11-12,15H2,1H3,(H,30,32) XPHQTRXVCZKOOQ-UHFFFAOYSA-N 79467 US20250387403, Example Table1.41 Sigma intracellular receptor 2 Homo sapiens 4.10 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79467 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79467&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597753 252656120 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123652 O=C(C1CNC1)N1CCC2CC1c1cc(-c3cccc(C(F)(F)F)c3)ccc12 InChI=1S/C22H21F3N2O/c23-22(24,25)17-3-1-2-13(8-17)14-4-5-18-15-6-7-27(20(10-15)19(18)9-14)21(28)16-11-26-12-16/h1-5,8-9,15-16,20,26H,6-7,10-12H2 MTLUCWDJFBHSNS-UHFFFAOYSA-N 79468 US20250387403, Example Table1.42 Sigma intracellular receptor 2 Homo sapiens 16.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79468 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79468&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597720 252656121 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123653 O=C(N1CCC2(CC1)CN(CCO)C2)N1CCC2C[C@H]1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C28H32F3N3O2/c29-28(30,31)22-4-1-19(2-5-22)20-3-6-23-21-7-10-34(25(16-21)24(23)15-20)26(36)33-11-8-27(9-12-33)17-32(18-27)13-14-35/h1-6,15,21,25,35H,7-14,16-18H2 QMBDDUHMCWEOPW-UHFFFAOYSA-N 79469 US20250387403, Example Table1.43 Sigma intracellular receptor 2 Homo sapiens 91.6 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79469 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79469&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597741 252656122 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123654 O=C(N1CC2(CN(CCO)C2)C1)N1CCC2C[C@H]1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C26H28F3N3O2/c27-26(28,29)20-4-1-17(2-5-20)18-3-6-21-19-7-8-32(23(12-19)22(21)11-18)24(34)31-15-25(16-31)13-30(14-25)9-10-33/h1-6,11,19,23,33H,7-10,12-16H2 GMMBMGZBLVSYGT-UHFFFAOYSA-N 79470 US20250387403, Example Table1.44 Sigma intracellular receptor 2 Homo sapiens 441 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79470 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79470&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289522 252656123 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123655 O=C(N1CC2CC(C1)N2CCO)N1CCC2C[C@H]1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C26H28F3N3O2/c27-26(28,29)19-4-1-16(2-5-19)17-3-6-22-18-7-8-32(24(12-18)23(22)11-17)25(34)30-14-20-13-21(15-30)31(20)9-10-33/h1-6,11,18,20-21,24,33H,7-10,12-15H2 LNFSOUFUSKJYTA-UHFFFAOYSA-N 79472 US20250387403, Example Table1.45 Sigma intracellular receptor 2 Homo sapiens 62.9 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79472 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79472&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597715 252656124 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123656 CN(C)CCC(=O)N1CCC2CC1c1cc(-c3cccc(C(F)(F)F)c3)ccc12 InChI=1S/C23H25F3N2O/c1-27(2)10-9-22(29)28-11-8-17-14-21(28)20-13-16(6-7-19(17)20)15-4-3-5-18(12-15)23(24,25)26/h3-7,12-13,17,21H,8-11,14H2,1-2H3 USGQYRWYKGKBPD-UHFFFAOYSA-N 79473 US20250387403, Example Table1.46 Sigma intracellular receptor 2 Homo sapiens 8.70 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79473 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79473&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597748 252656125 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123657 FC(F)(F)Oc1cccc(-c2ccc3c(c2)C2CC3CCN2C2CCCCC2)c1 InChI=1S/C24H26F3NO/c25-24(26,27)29-20-8-4-5-16(13-20)17-9-10-21-18-11-12-28(19-6-2-1-3-7-19)23(15-18)22(21)14-17/h4-5,8-10,13-14,18-19,23H,1-3,6-7,11-12,15H2 PIHWOXLWOLVMKU-UHFFFAOYSA-N 79474 US20250387403, Example Table1.47 Sigma intracellular receptor 2 Homo sapiens 79.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79474 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79474&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597729 252656126 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123658 CN(CCO)CCC(=O)N1CCC2CC1c1cc(-c3cccc(C(F)(F)F)c3)ccc12 InChI=1S/C24H27F3N2O2/c1-28(11-12-30)9-8-23(31)29-10-7-18-15-22(29)21-14-17(5-6-20(18)21)16-3-2-4-19(13-16)24(25,26)27/h2-6,13-14,18,22,30H,7-12,15H2,1H3 FUIGPZVUUTYKOP-UHFFFAOYSA-N 79475 US20250387403, Example Table1.48 Sigma intracellular receptor 2 Homo sapiens 4.30 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79475 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79475&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289523 252656127 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123659 CNCCC(=O)N1CCC2CC1c1cc(-c3cccc(C(F)(F)F)c3)ccc12 InChI=1S/C22H23F3N2O/c1-26-9-7-21(28)27-10-8-16-13-20(27)19-12-15(5-6-18(16)19)14-3-2-4-17(11-14)22(23,24)25/h2-6,11-12,16,20,26H,7-10,13H2,1H3 UYJLRZZCTQTRJI-UHFFFAOYSA-N 79477 US20250387403, Example Table1.49 Sigma intracellular receptor 2 Homo sapiens 4.90 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79477 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79477&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597736 252656128 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123660 Fc1ccc(-c2ccc3c(c2)C2CC3CCCN2C2CCCC2)cc1 InChI=1S/C23H26FN/c24-19-10-7-16(8-11-19)17-9-12-21-18-4-3-13-25(20-5-1-2-6-20)23(15-18)22(21)14-17/h7-12,14,18,20,23H,1-6,13,15H2 IAFPTGQLESNABD-UHFFFAOYSA-N 79478 US20250387403, Example Table1.50 Sigma intracellular receptor 2 Homo sapiens 153 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79478 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79478&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597744 252656129 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123661 Cc1ccc(-c2ccc3c(c2)C2CC3CCCN2C2CCCC2)cc1 InChI=1S/C24H29N/c1-17-8-10-18(11-9-17)19-12-13-22-20-5-4-14-25(21-6-2-3-7-21)24(16-20)23(22)15-19/h8-13,15,20-21,24H,2-7,14,16H2,1H3 FRODIIASTJBLHW-UHFFFAOYSA-N 79479 US20250387403, Example Table1.51 Sigma intracellular receptor 2 Homo sapiens 187 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79479 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79479&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597701 252656130 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123662 N#Cc1ccc(-c2ccc3c(c2)C2CC3CCCN2C2CCCC2)cc1 InChI=1S/C24H26N2/c25-16-17-7-9-18(10-8-17)19-11-12-22-20-4-3-13-26(21-5-1-2-6-21)24(15-20)23(22)14-19/h7-12,14,20-21,24H,1-6,13,15H2 OPMKUPBDVHUJDH-UHFFFAOYSA-N 79480 US20250387403, Example Table1.52 Sigma intracellular receptor 2 Homo sapiens 119 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79480 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79480&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597710 252656131 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123663 COc1ccc(-c2ccc3c(c2)C2CC3CCCN2C2CCCC2)cc1 InChI=1S/C24H29NO/c1-26-21-11-8-17(9-12-21)18-10-13-22-19-5-4-14-25(20-6-2-3-7-20)24(16-19)23(22)15-18/h8-13,15,19-20,24H,2-7,14,16H2,1H3 XLPTURNCCKLJLD-UHFFFAOYSA-N 79481 US20250387403, Example Table1.53 Sigma intracellular receptor 2 Homo sapiens 194 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79481 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79481&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597792 252656132 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123664 FC(F)(F)c1ccc(-c2ccc3c(c2)C2CC3CCCN2C2CCCC2)cn1 InChI=1S/C23H25F3N2/c24-23(25,26)22-10-8-17(14-27-22)15-7-9-19-16-4-3-11-28(18-5-1-2-6-18)21(13-16)20(19)12-15/h7-10,12,14,16,18,21H,1-6,11,13H2 QILATUIQYKUCRF-UHFFFAOYSA-N 79482 US20250387403, Example Table1.54 Sigma intracellular receptor 2 Homo sapiens 336 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79482&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597769 252656133 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123665 FC(F)(F)c1cccc(-c2ccc3c(c2)C2CC3CCCN2C2CCCC2)c1 InChI=1S/C24H26F3N/c25-24(26,27)19-7-3-5-16(13-19)17-10-11-21-18-6-4-12-28(20-8-1-2-9-20)23(15-18)22(21)14-17/h3,5,7,10-11,13-14,18,20,23H,1-2,4,6,8-9,12,15H2 HAYIQTLPIRHQQO-UHFFFAOYSA-N 79483 US20250387403, Example Table1.55 Sigma intracellular receptor 2 Homo sapiens 62.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79483&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289524 252656134 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123666 OC1CCC(N2CCCC3CC2c2cc(-c4ccc(C(F)(F)F)cc4)ccc23)CC1 InChI=1S/C25H28F3NO/c26-25(27,28)19-6-3-16(4-7-19)17-5-12-22-18-2-1-13-29(24(15-18)23(22)14-17)20-8-10-21(30)11-9-20/h3-7,12,14,18,20-21,24,30H,1-2,8-11,13,15H2 HZNNVRLKNPGUJP-UHFFFAOYSA-N 79484 US20250387403, Example Table1.56 Sigma intracellular receptor 2 Homo sapiens 39.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79484 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79484&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289525 252656135 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123667 O=C(C1CCNCC1)N1CCCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C25H27F3N2O/c26-25(27,28)20-6-3-16(4-7-20)18-5-8-21-19-2-1-13-30(23(15-19)22(21)14-18)24(31)17-9-11-29-12-10-17/h3-8,14,17,19,23,29H,1-2,9-13,15H2 LUVHEKUNIFTQQR-UHFFFAOYSA-N 79485 US20250387403, Example Table1.57 Sigma intracellular receptor 2 Homo sapiens 52.5 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79485 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79485&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 178289526 252656136 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123668 CC(C)N1CCCC2CC1c1cc(-c3ccc(C(F)(F)F)cc3)ccc12 InChI=1S/C22H24F3N/c1-14(2)26-11-3-4-17-13-21(26)20-12-16(7-10-19(17)20)15-5-8-18(9-6-15)22(23,24)25/h5-10,12,14,17,21H,3-4,11,13H2,1-2H3 CIZUDCYMWCTVNW-UHFFFAOYSA-N 79486 US20250387403, Example Table1.58 Sigma intracellular receptor 2 Homo sapiens 87.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79486 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79486&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597788 252656137 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123669 FC(F)(F)c1ccc(-c2ccc3c(c2)C2CC3CCCN2CC2CCCC2)cc1 InChI=1S/C25H28F3N/c26-25(27,28)21-10-7-18(8-11-21)19-9-12-22-20-6-3-13-29(16-17-4-1-2-5-17)24(15-20)23(22)14-19/h7-12,14,17,20,24H,1-6,13,15-16H2 GZIRANPLQYFDPZ-UHFFFAOYSA-N 79487 US20250387403, Example Table1.59 Sigma intracellular receptor 2 Homo sapiens 99.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79487&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597750 252656138 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123670 FC(F)(F)c1ccc(-c2ccc3c(c2)C2CC3CCCN2C2CCCCC2)cc1 InChI=1S/C25H28F3N/c26-25(27,28)20-11-8-17(9-12-20)18-10-13-22-19-5-4-14-29(21-6-2-1-3-7-21)24(16-19)23(22)15-18/h8-13,15,19,21,24H,1-7,14,16H2 JLIGDOAFDRGONX-UHFFFAOYSA-N 79488 US20250387403, Example Table1.60 Sigma intracellular receptor 2 Homo sapiens 25.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79488 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79488&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170403222 252656139 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123671 FC(F)(F)c1ccccc1-c1ccc2c(c1)C1CC2CCCN1C1CCCC1 InChI=1S/C24H26F3N/c25-24(26,27)22-10-4-3-9-20(22)17-11-12-19-16-6-5-13-28(18-7-1-2-8-18)23(15-16)21(19)14-17/h3-4,9-12,14,16,18,23H,1-2,5-8,13,15H2 NVQZUXYIWGICEM-UHFFFAOYSA-N 79489 US20250387403, Example Table1.61 Sigma intracellular receptor 2 Homo sapiens 549 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79489 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79489&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 170597767 252656140 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823 123672 FC(F)(F)c1ccc(-c2ccc3c(c2)C2CC3CCCN2)cc1 InChI=1S/C19H18F3N/c20-19(21,22)15-6-3-12(4-7-15)13-5-8-16-14-2-1-9-23-18(11-14)17(16)10-13/h3-8,10,14,18,23H,1-2,9,11H2 NYGRLRGSMDNJTN-UHFFFAOYSA-N 79490 US20250387403, Example Table1.62 Sigma intracellular receptor 2 Homo sapiens 21.0 US Patent 10.7270/Q24B3638 US20250387403 MARTIN, SF; SAHN, JJ 12/25/2025 5/6/2026 University of Texas System http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79490 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=554&target=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79490&enzyme=Sigma+intracellular+receptor+2&column=ki&startPg=0&Increment=50&submit=Search 144777803 252656141 1 MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK Sigma intracellular receptor 2 SGMR2_HUMAN Q5BJF2 B4DS02 Q07823